Aepi007864.1
Basic Information
- Insect
- Anopheles epiroticus
- Gene Symbol
- -
- Assembly
- GCA_000349105.1
- Location
- KB671843:300629-302327[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00017 0.011 15.6 1.4 2 23 175 196 174 196 0.97 2 9 2.3e-06 0.00014 21.6 0.6 3 23 204 225 203 225 0.97 3 9 0.011 0.69 9.9 0.9 1 23 233 257 233 257 0.96 4 9 3.1e-07 1.9e-05 24.3 0.8 2 23 270 291 269 291 0.96 5 9 0.00015 0.0093 15.8 6.1 1 23 297 319 297 319 0.97 6 9 2.2e-05 0.0014 18.4 1.8 1 23 325 347 325 347 0.98 7 9 0.0004 0.025 14.5 0.2 2 23 354 376 353 376 0.96 8 9 7e-07 4.3e-05 23.2 1.8 1 23 382 404 382 404 0.99 9 9 0.0001 0.0062 16.4 4.0 1 23 410 432 410 432 0.99
Sequence Information
- Coding Sequence
- ATGAAATTTTCCTGCGTTATTTGCGTGGAGGTGCACAATTTAGCGCATGTTACGAAGTTGATCGACGTTTCGGACATATTTTTCAAGCTCACATCGCTGGAGGTATCAGCTTTGCAAGATATTCAACTGCTGAGAATTTGTGAAATATGCCACCAGAAGTTGGAGGATTTCGATCGCTTTCGCACTCTGTGTGTGGCTGCACACACTAAACTCACGGAGGAAAACGAGAAGCTGTCGAAGCTCTCCATCGTCAAGTTTGATGAAGTAGAAGAGCAATCCGAGCCGATTGCGGCAGATGATGGTAACGATGCATCAACAGACGATGAAATCCCCGCGGACGAACCTCAGTTTGACATTGAACCACTTGATAATGTCGCCGTGAAGGAAGAACTGGAAGCATCCGAAGATGGTGAGGAGCTACACGCGGAGGAGCTATCTCCACCTCCGGAGAAAAGCAAACGTGGAAGAAAAAAGGGGAGCACCACCGTGAAGAAACCAGCAGCAACACCTCGGGTGGAGCTGTCGTGTCACTTGTGCGATGAAAAGTTCCGCTCGCAGATCCGTCTGGAAGGGCACCTTCGCATGCACAAAGGGTTGAAACCGGCGCTCTGTAAAGAGTGCGGTAAAGAGTTTGCCGGATGGCGTAGCTTGCGACGGCATATGAAGGAGAAACATTTGAAGCTCGATATTGGGTATTTTCCGTGCGATTACGAGGGCTGCACCTATGCGTACACCACCCGGAAGGTGTTGCTACAGCACAAGAAAAAGCACGAGCCGGGATGGGTGAAACCGGTGCCGAAGAAGTGTGTTTGTGAAATGTGCGGCAAAACGTTTTCCTCTGCCGGTGCGCTGAAGAAACACACAATGATTCACACGGGTGAGTTGCAATTCCACTGTGAAATTTGTGACAAGCGTTACTGTACTGCCTACAAGCTGAAGGTGCACAAGATGCGCCACCAGGGCATTCGAAACTACGAATGTTCTTACTGCGGACAGAAGAAAACTACGTCCGACGAACTGAAAAGGCACATGAACTACCACACCAAGGAGAAGGTGCTCACCTGTGACCTTTGCGGGCAAGTGTTTCTTTCCTCAGGAAATTACTCACGCCACCTAAAGGTCGTACACTGCGGGATAAAGAACTTCAAATGTCCCCACTGTGAGCGTACCTTCGGTAAGGCGGAGACGCTTAAAAACCACATCAtgacacacaccggggaaaagccgtaccaatgtacggtgtgctcgaagcgcttcatccaactgtgtgcgctgaaaacacactccaagacgcacGACAAGGTACGGAAACAGTCTAAGCAGTGCAATTTAAACGAAAACAACAGCGGTAGCACTACCAACAGCAGCGCTACAGAGGTGCAATAG
- Protein Sequence
- MKFSCVICVEVHNLAHVTKLIDVSDIFFKLTSLEVSALQDIQLLRICEICHQKLEDFDRFRTLCVAAHTKLTEENEKLSKLSIVKFDEVEEQSEPIAADDGNDASTDDEIPADEPQFDIEPLDNVAVKEELEASEDGEELHAEELSPPPEKSKRGRKKGSTTVKKPAATPRVELSCHLCDEKFRSQIRLEGHLRMHKGLKPALCKECGKEFAGWRSLRRHMKEKHLKLDIGYFPCDYEGCTYAYTTRKVLLQHKKKHEPGWVKPVPKKCVCEMCGKTFSSAGALKKHTMIHTGELQFHCEICDKRYCTAYKLKVHKMRHQGIRNYECSYCGQKKTTSDELKRHMNYHTKEKVLTCDLCGQVFLSSGNYSRHLKVVHCGIKNFKCPHCERTFGKAETLKNHIMTHTGEKPYQCTVCSKRFIQLCALKTHSKTHDKVRKQSKQCNLNENNSGSTTNSSATEVQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -