Aepi002236.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles epiroticus
Gene Symbol
-
Assembly
GCA_000349105.1
Location
KB671724:88611-95518[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0013 0.078 12.9 2.9 2 23 417 438 416 438 0.97
2 25 0.0026 0.16 11.9 2.2 2 23 445 466 444 466 0.98
3 25 0.044 2.7 8.1 1.8 1 23 476 498 476 498 0.96
4 25 0.96 59 3.8 0.3 3 23 526 550 521 550 0.74
5 25 0.65 39 4.4 1.3 2 23 557 578 556 578 0.89
6 25 0.6 36 4.5 0.3 1 23 584 604 584 604 0.85
7 25 0.00013 0.0081 16.0 0.3 1 20 616 635 616 636 0.97
8 25 0.0065 0.4 10.7 1.0 2 23 645 666 644 666 0.97
9 25 1.4e-05 0.00083 19.1 0.6 2 23 672 693 671 693 0.96
10 25 0.22 14 5.8 2.3 2 23 702 723 701 723 0.95
11 25 0.00019 0.012 15.5 1.9 2 21 730 749 729 750 0.94
12 25 0.0025 0.15 12.0 3.1 1 23 761 783 761 783 0.98
13 25 0.00072 0.044 13.7 2.5 1 23 789 812 789 812 0.98
14 25 0.0033 0.2 11.6 3.4 2 23 1225 1246 1224 1246 0.97
15 25 0.014 0.85 9.6 2.8 2 23 1253 1274 1252 1274 0.98
16 25 0.056 3.4 7.7 1.1 1 23 1284 1306 1284 1306 0.95
17 25 2.2 1.4e+02 2.7 0.0 9 23 1343 1358 1330 1358 0.83
18 25 0.29 18 5.5 2.0 1 23 1392 1412 1392 1412 0.95
19 25 0.00024 0.015 15.2 0.5 1 20 1424 1443 1424 1444 0.96
20 25 0.0046 0.28 11.2 1.3 2 23 1453 1474 1452 1474 0.96
21 25 0.0003 0.019 14.9 0.4 2 23 1480 1501 1479 1501 0.95
22 25 5.1 3.1e+02 1.6 2.4 3 23 1511 1531 1509 1531 0.91
23 25 0.0033 0.2 11.6 1.9 3 21 1539 1557 1537 1558 0.94
24 25 1.6e-05 0.00097 18.9 0.6 1 23 1569 1591 1569 1591 0.99
25 25 0.00072 0.044 13.7 2.5 1 23 1597 1620 1597 1620 0.98

Sequence Information

Coding Sequence
ATGGCGTACAATGCTACCTGTGCGCTTTGTTTAACGACCGACGCTCAATGGTTCATGGAAGTGTTCGATGAAACCAACAGGACGCTCGATATGGCACTGATTATATCTAAACATCTATGGTTCGATCTAAAACCAGCAGCACAGCCTTGCATCTGTGGGGATTGCTGGACCAGCATACACGATTTCCATCTATTCTACACCAAGCTGGAGAGTATTCACAGTGATGAGATACACGCTGTGAATTCGTCCGAGCAACAAACTACTGAACTTGAGGTACAAGAACCGCAGCACCACGAGGAGCACTTGCAAGAGAAAATTGTAGACGAGCAAGAAGACAGGAGCTCTAAAATAATTGAAACCGGTGTGAAAATGATACCATCGATTGCCAGTACTAACGTGGTGTTGCAATACCATGCAACGGAAACATCTGACACAATGACCACATCGGAAAAGAAGCATTTTGTAGAGGTGGAAGATTATGATAGCAACGATAATGAAGATGATTGCGAAGCATATTGTCCATCGGATGATAATATGCTCGACCATGATACACTGAATTCCGACAGCAAGGAAAAAATATTAGCAGGAATGTCAAAAAGAAGCAACGTACCTATGGTCACTGTCGTTCCCGCAGAACAACCCGCAAAACGGGGCAGAGGACGCCCGCCAAAGCAAAAAGTGGAACTGCGAAATGAAGCATTAAGCATAACAGAAACCATTATTGATTCATGTGCTTCAGAACCGCCTGTAAAACGTCCCAGAGGACGGCCACCAAAACGGAAGCAGGACACTCTGAACAAGGAATTAAAAGTTGAAGAACCTCAAGCTATCATTCATACGCCTGTCCCTGCAATAAACGAACCCATTAAGCGACGAAGAGGTCGGCCACCTAAAAATTCATTTGCCGCTGATCCCATTCAGTCTATCGCTGCAGTGCATGCTAATGGTAAGATAAAAATTGAAAAAGATAGCCAATCACCATCGGAAGAGCAACACACAAAAGCAAGCCGAAAGGTAATTCGTGGTCAGAAATTAAATGAAGAGAGTGAAAACGAACTGGACAATGAATCAGACTATGAGGTTCGAAAGCAGAGGCCAGTAAAGCGTGAGAAAAGTGATCGGGATGAGCGAATATTCAAGTACGTGGACGAATTTTGTTGCCACTATTGTGTGGAAAACGTATCGTTCAAACGGTTCATCGATGCGGACCGCCACTACAAGCTGGTACACAACGAGCCGGGCTTTTTGAAGTGTACCAAGTGTGACAAGAAATGTTTTACGCCCGGTATGTTCGTGAGCCACATGGAGACGCACGAAGATCCGGaaaaaaaTAAATGCAACATTTGCGGTAAAATTACGGACTGTAACATCTCTCTCAAAAAGCACATGCGTGTGCATTTGAGTCAACTGGAGGAGAATTTACCGTTCCCTTGCAGTCGCTGCAAACGAAAGTTTGAAACGGAGGAGCTGCGAAACAAGCATGAAAAGCTGCACGTCCCCAAACCGTTGGTAAAACGTGAAAAGGGTCCCGATCTGGAGCTGCTTGCGTTCTACAAACGCATCTACTGTGATGTGTGCGAAAAGCAATGTCCCGAATCGACCTCGTTTGAAAACTTCTGGGACCTGCGGGTACATATGGAGCAAGAGCACAACAAGGGAGCATACCTGAAGTGTCCAATTTGTAACAAGCGGAATTTGTACCGGCAACATCTTATCACACATATCGACATGCACAACAATCCGGAGAAGTATCGGTGTGAAGTTTGTAAGGAAGTCTATCAGAATCTAGATTCGCATATGATTAAAGCCCATACGCCCACCACTGCCATTCCGGCGGATAAGAAGTACAAATGTGAGCAATGTGGACGAATGTTTAACTTCCTTGCTAATTTGAAAATGCATCTCGACTGCGTCCACGGCTCGAAAGACGTTCGTTGCAATGTGTGTAATAAATACTTCAATCTGAAAGCCTTCCAAGTGCACAAGCGAACAGCTCACACCGATCAGATGCTGATGTGCGAACATTGTCCTAAAATGTTTAAAACACGTGGCGCGCTAGAAGCGCACAAAGCCACGCACGACGATAGTTTAGTGCAGTTTACGACCTGTAAGCTCTGTAACAAGCAGATCAAGAACAGCAACGTCAAGAAGCACATGACCTCACAGCACTCCGAGGATGGACCGGTGAGCTGTGAGCTGTGCGGCAAAACGTTCCGCACCATGTTCCACATGAAGCGGCACCAGAAGAACACCTGTGAGGCGACGATCGATTCGCGCAAACACAAATGTGAGGTGTGTGGGAAGGGTTTCTGTTTGAAGCTAACCATGATCGAGCATATGACGACACACACGCGCACAAACAAGTACCAATGTGCGTTCTGCTTTAAATCGTTTGGTTACATCTCGAATCTGTACAAACACCGGAAGAAGGCGCATCCACTCGAGTGGCAAGAAATACTGGCCCGCCCGGAGGAGGGCATCGCGTCGGTTATCATGCTGATTCCCGCCAACGAACCACACATTTGCATGGATTGCTGGACCACCATACATAACTTTCATCGATACTACACAAAACTGGAAGACATCCATGGCTGTTTTTCGGATGATTGTATCAAAACCGATGAGACGACCACGGATTACGGTATAGAAGAGTTGGAAAATATTGAGTTCCTGGAGGAAGATGCAGAGGAACTGCGCATGCAGATGAAGCACTTGAATGATGATTCCTCGTTATACGAGATCGGTGAGCACGGTAACCCCAAAACAAATAATTCTCAAGAGCAGCGCACCAGTTCTTCAGCATTCTGGAATAAAGAAGAGATAAAGGTTTTGGAGATCGAAGTAGAGGATGACGAGCGAGGGGGAATGATTTACCGTTTGGATGGTTTTCAAGACGATGCAACGGACGGTACGGCCAAATCGGAAATCCTTCGGGGGCCCGTTATACTAAACGGTCAAATGAAGATGAATCCCGCCACGGAAAGTTCTACCATTGACATCGACGTCTTGGCAGCCGAACAACAGCCCGTTAAGCGTGGTCGAGGTCGCCCACGGAAACATCCGAAACCCGACCTGCAGCTGCCTATACAAAGTGTGAAGCAAGAACACAATTCAAGCATCGACGAAAATAACACTTCCATGGATTCGACCGGCAACGATGAGGAAGTGCCCGTGAAACGTCGCCGAGGTCGTCCACCAAAGAATGCAAACGCTCAGCAAACTGCTTCTCCTGTCGAATCGACCCCACAGTATATCAAGAAAGAGATAAAGACGGAAAGTCAGGACGAGGAATCATCAGACGCTCAACATAACGCACGAGCGGAACGGAGATCGACCCGCAGACGGAAGCCAAAACACTACAGTGATATGGAACAGGGTAGCGAGCTGGACGAGGAGGAAAGTGCGGAAGGGGAGGAACAAAATGAATATCAGCCAGGAGACGATCCGGAGTATGACGCAAGGCTCGAGCTGCAAAAGTCCCTAAACATGGACGATTTTGCCTTCTACGAGTATCAGTGCAACATGGAATCGGAACAGGCGGCACGCGATAATAAGATCTTCCAGTACGTGGACGAGTTTGTGTGTCATATCTGCATGGAGAAGGTTACATTCAAAAAGTTCGCCGAGGCACACCTGCACTACCGGGTCGAACACAACCAGCCGCCGTTCTTGAAGTGTCCAAAGTGTGAGAAGAAATGTCACACACCGGGCATGTTCGTAAGCCACATGGAGACCCACGACGATCCGGAGAAGAATAAGTGCCAGATTTGCGGAAAGTACACCGATTGTAACATATCGCTTAAGAAGCACATGCGAGTGCACCAGAGCGAACTGGAGGAGAACCTACCGTTCCCGTGCAGTTTGTGCAAGCGAAAGTTCCAGACGGAGGATCTGCGGGCCAAGCACGAGAAGCTGCACGTACCAAAGCCGTACGTACCGAAGGAAAAGGGTCCGGATCAGGAAGTGCTGGACTTTTACAAAGTGATCGTGTGCGATGTGTGCGAAGAGGAACAGGTCGGGTCGCCGACGTACGATAACTTGAGCGATCTCCGCACGCACATGGTGAAGGTGCACAACAAGAATATGTACGTGCGGTGTCCCGTTTGCTTAACCAGACAGGTAAACCGCCAGCAAATCATCACGCACATCGACATGCACAATAATCCGGACAAATATCGATGCGAAGTGTGCAAAGAGGTGTACCAAAATCTGCACCAGCACATGATGAAGGCACACGCGGCAAATACGGCGGAACCGGCGGAGAAACAGCACAAGTGCGACCAGTGCGGTAGGATGTTCAACTTCCTTGCCAACTTGAAGATGCACATTGATTGCGTCCACGGTGTGAAGGACGTTCGATGTAACATTTGCGACAAGTACTTCAACTACCGAGCCTACAAAACCCACAAACGTACCGCTCACACCGACCTGATGCTGATGTGCGAACTCTGTCCGAAGATGTTCAAGAATCGGAAAGCGTTCGAGGCACACAAAGCTTCGCACGACGGTATCCTGCTGCGCATGACCAACTGTGAGCTGTGCGGCAAGCTCATCCGTACCTGCAGCATGTCGAAGCACATGAAAACGATCcactcgaacgaagatccggtcaattgcgatctgtgcgggaagctgttccgcaccacgttccacatgaagcggcaccagaagaacacgtgcgaggtgacgatgaattcgcgctcgttcaagtgcgacgtctgcgggaagggtttctccACTAAGCTGACGATGGTGGAGCATATGACGACGCACACGCGCACCAATCAGTATCAGTGTGCGTTCTGCTTCAAATCGTTTGGCTACATCTCGAACCTGTACAAGCACCGGAAGAAGGCGCATTCGTTCGAGTGGCAGGAGGTACAGGCGCACCCGGAAGAAAACATTGCCTCGGTGATCATTGTTGGCACGTGA
Protein Sequence
MAYNATCALCLTTDAQWFMEVFDETNRTLDMALIISKHLWFDLKPAAQPCICGDCWTSIHDFHLFYTKLESIHSDEIHAVNSSEQQTTELEVQEPQHHEEHLQEKIVDEQEDRSSKIIETGVKMIPSIASTNVVLQYHATETSDTMTTSEKKHFVEVEDYDSNDNEDDCEAYCPSDDNMLDHDTLNSDSKEKILAGMSKRSNVPMVTVVPAEQPAKRGRGRPPKQKVELRNEALSITETIIDSCASEPPVKRPRGRPPKRKQDTLNKELKVEEPQAIIHTPVPAINEPIKRRRGRPPKNSFAADPIQSIAAVHANGKIKIEKDSQSPSEEQHTKASRKVIRGQKLNEESENELDNESDYEVRKQRPVKREKSDRDERIFKYVDEFCCHYCVENVSFKRFIDADRHYKLVHNEPGFLKCTKCDKKCFTPGMFVSHMETHEDPEKNKCNICGKITDCNISLKKHMRVHLSQLEENLPFPCSRCKRKFETEELRNKHEKLHVPKPLVKREKGPDLELLAFYKRIYCDVCEKQCPESTSFENFWDLRVHMEQEHNKGAYLKCPICNKRNLYRQHLITHIDMHNNPEKYRCEVCKEVYQNLDSHMIKAHTPTTAIPADKKYKCEQCGRMFNFLANLKMHLDCVHGSKDVRCNVCNKYFNLKAFQVHKRTAHTDQMLMCEHCPKMFKTRGALEAHKATHDDSLVQFTTCKLCNKQIKNSNVKKHMTSQHSEDGPVSCELCGKTFRTMFHMKRHQKNTCEATIDSRKHKCEVCGKGFCLKLTMIEHMTTHTRTNKYQCAFCFKSFGYISNLYKHRKKAHPLEWQEILARPEEGIASVIMLIPANEPHICMDCWTTIHNFHRYYTKLEDIHGCFSDDCIKTDETTTDYGIEELENIEFLEEDAEELRMQMKHLNDDSSLYEIGEHGNPKTNNSQEQRTSSSAFWNKEEIKVLEIEVEDDERGGMIYRLDGFQDDATDGTAKSEILRGPVILNGQMKMNPATESSTIDIDVLAAEQQPVKRGRGRPRKHPKPDLQLPIQSVKQEHNSSIDENNTSMDSTGNDEEVPVKRRRGRPPKNANAQQTASPVESTPQYIKKEIKTESQDEESSDAQHNARAERRSTRRRKPKHYSDMEQGSELDEEESAEGEEQNEYQPGDDPEYDARLELQKSLNMDDFAFYEYQCNMESEQAARDNKIFQYVDEFVCHICMEKVTFKKFAEAHLHYRVEHNQPPFLKCPKCEKKCHTPGMFVSHMETHDDPEKNKCQICGKYTDCNISLKKHMRVHQSELEENLPFPCSLCKRKFQTEDLRAKHEKLHVPKPYVPKEKGPDQEVLDFYKVIVCDVCEEEQVGSPTYDNLSDLRTHMVKVHNKNMYVRCPVCLTRQVNRQQIITHIDMHNNPDKYRCEVCKEVYQNLHQHMMKAHAANTAEPAEKQHKCDQCGRMFNFLANLKMHIDCVHGVKDVRCNICDKYFNYRAYKTHKRTAHTDLMLMCELCPKMFKNRKAFEAHKASHDGILLRMTNCELCGKLIRTCSMSKHMKTIHSNEDPVNCDLCGKLFRTTFHMKRHQKNTCEVTMNSRSFKCDVCGKGFSTKLTMVEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHSFEWQEVQAHPEENIASVIIVGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-