Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB671325:133967-142881[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.019 1.2 9.2 6.3 1 20 347 366 347 370 0.95

2 21 0.00089 0.055 13.4 0.8 2 23 378 399 377 399 0.97

3 21 3.7e-05 0.0022 17.7 0.2 1 23 407 429 407 429 0.98

4 21 0.00026 0.016 15.1 6.9 1 23 435 457 435 457 0.98

5 21 3.5e-06 0.00021 21.0 2.8 1 23 463 486 463 486 0.97

6 21 1.1 70 3.6 3.5 1 23 511 535 511 535 0.98

7 21 2.8 1.7e+02 2.4 1.0 2 11 540 549 539 553 0.86

8 21 7.9 4.8e+02 1.0 2.6 2 23 770 791 769 791 0.93

9 21 0.25 15 5.7 1.1 1 23 797 828 797 828 0.90

10 21 0.94 57 3.9 2.2 2 23 833 855 832 855 0.88

11 21 0.037 2.3 8.3 0.4 1 23 864 886 864 886 0.98

12 21 3.6e-05 0.0022 17.8 0.7 1 23 894 916 894 916 0.98

13 21 5.6e-05 0.0034 17.2 2.4 1 23 922 944 922 944 0.96

14 21 3e-05 0.0018 18.0 1.1 1 23 950 972 950 972 0.97

15 21 0.0088 0.54 10.3 0.1 1 17 1017 1033 1017 1034 0.92

16 21 2.8 1.7e+02 2.4 0.1 2 23 1446 1467 1445 1467 0.94

17 21 0.36 22 5.2 0.1 2 23 1524 1548 1523 1548 0.95

18 21 6.5e-05 0.004 17.0 2.9 1 23 1552 1574 1552 1574 0.97

19 21 6.3e-07 3.9e-05 23.3 1.4 1 23 1580 1602 1580 1602 0.98

20 21 6.2e-08 3.8e-06 26.5 1.2 1 23 1608 1630 1608 1630 0.98

21 21 0.0012 0.074 13.0 0.6 1 23 1636 1659 1636 1659 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.019	1.2	9.2	6.3	1	20	347	366	347	370	0.95
2	21	0.00089	0.055	13.4	0.8	2	23	378	399	377	399	0.97
3	21	3.7e-05	0.0022	17.7	0.2	1	23	407	429	407	429	0.98
4	21	0.00026	0.016	15.1	6.9	1	23	435	457	435	457	0.98
5	21	3.5e-06	0.00021	21.0	2.8	1	23	463	486	463	486	0.97
6	21	1.1	70	3.6	3.5	1	23	511	535	511	535	0.98
7	21	2.8	1.7e+02	2.4	1.0	2	11	540	549	539	553	0.86
8	21	7.9	4.8e+02	1.0	2.6	2	23	770	791	769	791	0.93
9	21	0.25	15	5.7	1.1	1	23	797	828	797	828	0.90
10	21	0.94	57	3.9	2.2	2	23	833	855	832	855	0.88
11	21	0.037	2.3	8.3	0.4	1	23	864	886	864	886	0.98
12	21	3.6e-05	0.0022	17.8	0.7	1	23	894	916	894	916	0.98
13	21	5.6e-05	0.0034	17.2	2.4	1	23	922	944	922	944	0.96
14	21	3e-05	0.0018	18.0	1.1	1	23	950	972	950	972	0.97
15	21	0.0088	0.54	10.3	0.1	1	17	1017	1033	1017	1034	0.92
16	21	2.8	1.7e+02	2.4	0.1	2	23	1446	1467	1445	1467	0.94
17	21	0.36	22	5.2	0.1	2	23	1524	1548	1523	1548	0.95
18	21	6.5e-05	0.004	17.0	2.9	1	23	1552	1574	1552	1574	0.97
19	21	6.3e-07	3.9e-05	23.3	1.4	1	23	1580	1602	1580	1602	0.98
20	21	6.2e-08	3.8e-06	26.5	1.2	1	23	1608	1630	1608	1630	0.98
21	21	0.0012	0.074	13.0	0.6	1	23	1636	1659	1636	1659	0.93

Sequence Information

Coding Sequence: ATGTCTGCCGAATGTTCAGACTCCAATAGTGACCGGAAGCTGCTGCTTTATCGAGACCTATTCTGTCGAATATGTCTCCAGTACAGCAAAGGTGCGCTGATTCCGATCGATGCGGAGATAAAGAAAACGACACTGCTAGATATGTTTATACAGCTCACCACCTTTGAGATCGATCATAATGATGCATATCCAAGGTTCATGTGTGAACAGTGTGTCAGCAAGCTGACACTGGCCTACAGTATTCGGGAGGAGTTCATATCCCAAACAGACCTACTGCTAAAGCTAGTGGCACAGAAGCAAATAATTAAATACTATGAACAGTTTCCACTGGACGAAAATGCAAGCGTGCCGGCCCCGAAAACACAGCCCTCCGAATATGCACCCTTTCGGGACGTAAAACCTCCGAAGGCGGCAAAACCAAAGGGATCATCGATCACGGCAGTGCGACCGGAAAATTTGGTAATACCGGAAAATGAAAAACACGAATCAATGGAGGTGTTAGAAGAGGCTGAGGATCTCGTTCGGGAGGAATACCTTAACGAAACTAGCTTGCCATCGCAGAACGTGAGCAGTTTAACGGACTTTAGTAAGGACTGGGAGTCGTCCAGTACGACTACCTCGCTCGATGAGGATGATTGGAGCTACTCGCTCAATCCGATAACACCCCAAAAGCTAGAGGAGCTGAAACCCGTCAAACCAGTGCGCAAAAAGTACCCGAGCAGTACGCGCAAACGTGTCAAAGCGGAGGCAGGAAACCAGGAAAAGAAGCAAAGGAAAAATCAATACTCTACCACCACGTGCTACATTTGTGATACGCAGCACGAGACGATTGCGGAGCGTGATGATCACTTCCGCCACCACATTCATATGCTACCGTACGAATGTACGGAGTGTGTAGCCGATCCGACACCAGAAGACTCCCCGACCAAAGAGGAAAGTCAACCTGCGGATACGACGACGACGGCACCAACCACCAAACACATTGTGCTGCGCAGCGTGATCCAGCTCAACAGCCATATGATGATGCACGGTTTTCCGCACAAGTGTGAACATTGTTACAGACGGTTCACCACCACTTACCTGTTGAATCACCACCTCTGGAACTACCACCAGCACTCGAAGGAGGGGCTGACGTGTGAATGGTGCGGCAAGCGGTACTACTCACGACGGCCCTTCCAGGAGCACGTGAGGCGCCATCGGCATTCCGTTACCGAGCGGTTCAAGTGTGTAACGTGTGGCCGGGCGTTCGGTTCGAACGCACTGCTCAGACGGCATGAGATGGTGCATACGGGCGAGCGTAGCCATAAATGCACCTACTGCTCGCGTATGTTCAGTCGTCGATGCAATCTGCTCGATCATCTGCGTCTCCACACCGGCGAACGATGTCACAAGTGTAACGAATGTCCACAATCTTTCAACTCGAAAGCATCGCTTGAAAAGCACCAGCGCAACTATCACAGCGATCTGGCCGTGGTGCCACCACGTGGCGATCGTAATATTTACACACTGCAAGCGGACGGTACGCGGCTTTACCGCTGCAAGCACGAGGGATGCACGTTTACGAGCGTGTCCAGCACAACCATGACCCAGCACAGACTGCGGCACAATAAGCCATGCGTTTGTGAGGAGTGTGGCCAACGTTTCGTTGCACCGAAGTACTCCTACGCTACGCCACCTCAAACCACCGTCCTACAGCGATTCTGCCGGCTTTGTTTGCGAGAACATCCATTTCTGTTGCCGTTCAATGCCACCCTCGAGGACACCACGCTGGCCGACATGCTGGAACGGCTGCTGGGTTCATTCAAGCTAAAGCAAACGCCAAATCTGCCGAACGGTGTTTGCTCGCACTGTGTGACGAAGTTAAACTATGCGTACCAGGTGCAGAAAGAACTGGTACGAAACGAGCAACGTTTAAGACATTATCATCGAGGTGGAAACGTTCTGGAGAGGTTGTTTGAATATCAAACTAAAATTACTGCAACGAAAGAGGGTAGAGTTGTGAATCGAATGGTGGCCCAGCATGGTGATGGACTGCTAACAGAAACCATTAGCGTTGAAGCAAGCGTGGACGCACCGGATATGCGAGAGGAGGATACGCGAGCTGCAGCGATAGCTAAAACGTTAGTACCAACAGGCGGTTGGGCTGTTATAGCGTGCGATTGCCCGGCGAAACCAGTGGCAGTGACTCGGCGTCCAGTAAAACCTGTGCGTGCGGTAAAGCGAACTTTGCGCAGTCGACGGGTGCTGCGGCAAGCCATAGACGCAGGGAATCCTACCGCTTTGAATGCTTCCCCAATTGATCCCTGTAAATGCTACATATGCAATACCGTGCTAGAGTCGGAGGCATCCTGTAGGACTCATTTGGCTATGCATGTGGACATGCTGCCACACATCTGTCCGGATTGCGGCACACCGGATGAGGAAGGTGCTACGAACAGACCGATCACTTCGTTGGCAATGTTGCAGCGCCATTATCGGACGCATTCCTATCCTCTGAAGTGTCCGCACTGTCCGCAACGGTTCTTAAAGTACACATCCGTCTACTCGCACGTACGCTACCGACACGAGCTGTTCGACAGTCCGGAAGGATTCACGTGCGACGTGTGTGGCGTCACGATGCAATACCGTCCTTCCTTTATGTACCACATGCGCATTCACTACCACGAACAGATGGGCACGTTCCGGTGCCAGTACTGCGACCGTGTGTTTGGAACGCGCGCCCGTCTGGAACGTCACGAACGAGCGCATACTGGCGAGCGTCCGTTCGCTTGCCACCAGTGCCCGAAAACGTTCGCGCACAGGGGCCAACTGGCAACACATACCGCGCGACACAATAACGAACGCGGTCATCAGTGTGCCCAATGCGGAAAGGCGTTCTTTAACAAAGCAATGCTACGACAGCATCTGGCATCTCATGAAACGCTCGAAACGCGTAAAACGAGCAGCGTAGCAAAGGTACGCCAAAGGCCCTGTTCGTATGCGGGCTGTACACACGTTGCCCACACGTACCAGGCGTACTACATGCATCGATTACGCCACGAAATGGCACATCGATGTGACGAATGTGGAAGACGTTTTGCACAACATGGGACGTTGACGGAGGGGGAGGACGACGAAGGGGATGAGCAAAAGATTGTGCTGATGAATGCAGAAGATCCGATAATGGATGTAATACTGGAGGAAAGTGCACCGCAGGGCATACTGATCAATGAAGACATTGAGCTGGATGGTACGTACGAAGAGGAAATAGAAACGGTGGAAGAATCGATCGTCGTGGAGCAACCGATCGTTAGCATTGGCATCGATGAGGTGACCAAGCAAGAGTACATTATAGACATGGAAAAAGTCGACACAAGAAGGCCGAGCCTTTGCATCAGCGCAACGTCGTCCGCTGAAGCGACTTCAGGCGACTTTTGTCGAATATGTTTGCTGAAACGGCCCCACCTAACGTCGCTGATGGAGCGCATCGACGGTGTGATGATTCCGGAGATGCTGTACAAGCTGTGCGGACGGCAGATCGAGGTGCAGGATAACTACCCGCGCAGCATCTGCCAACGGTGCCTGTGCCAGTTGGACTGTGCATATAAATTTTTGAACGAGTTCCACCAGCAGGACGAACGTTTACGAAGCTTCTACTGGAGCGGTTCGGTGGTGAAACGATTGCAAGAGTATCAACCCGAAGGGGCCAAGACGGTGGAAAAGCGAATGGCCGAACTGGTCAGCCGTAATACGGCGCTGTTCACCCCACCAGCGAAGGAGATGTGCCACAAGCAGACAAACACGAAGCGTCACCCGAAGCTGGTAGATGTAGGCACGGTAACTGATAAGGTGTTGGAGGTGGATATGTCATTGATTAAAACGGAATCGGCGGACGAAGATATACTGCTAGAGCAATATGTTATGGAGGATGAAAATGAGGACCGATATCTTGACTACACTGACGATCAAGATTCGAGCTCAGTGAATGAACAGCATCTGGTATCGATGAAAATAGACGTACTCCGGGGGCTGGACGCAACGGAACCGCACAGTAGCGAAATGAAAACGCGCAGAAAGAAGGAAAAGCAGGAACCCGTCAGCCAGCGAACACCACGACAACGGGAAGCAAAATCAAGGCATGCTTTGATGCAAAAGGTGAAACAGCCAAGCCTACCAAGCACTCCAAGCGAAACAGACGATCAGGGAACGGAGGAAGATTTTAAGGAGCTGTTTGAGGACAGTGATGCAGCAGACGCCaaggaggaagaagaagaggaggaggaagaggaaAAGTATGCAGACGAAGTGCAAGAAGATAATGACGAGGGACAAGAAATAGAACCACTCGATCCACTGCGCTGCTATATATGCGAACAAACCGAAGAAACGGAGGCAATGCTTGAACAGCACCTCGACATGCACAGCCTGATGCTGCCGTTTGAATGCAAATCGTGCAAGGTGGAGGGGGCTCCCGCCCCCCTCGACGAGCACAAGGTCGAGAAGCATTTGCGCGGTGCCGAACTGGAAGCGTTTTTAGCGCGCAAGGAAAAGCAGCGCACTGTGAAGCGCCCGGCAAGCTTGAAGGATAAGGAGTGTCCGTATCCCGATTGCGATTACGTGGCAAACACGTATGGGGCCATGTATGTGCACAAGCGCACCAAGCATCAGCCGGTGCATCGGTGCGATATGTGCAACAAATCGTTCGCCTTTCTTAACCAACTGAACATGCACATGAAGCTACACACTGGAGAGAAACCGTTTCAGTGTGAAATTTGTGGGCGTAGCTTCCGCCGTAGCTTTAGCTACCGGGAGCACATGGAGATGCACGTCACGGACGCGACCTACAACTGTCCCACGTGCAACAAAAGCTTCAAACGGCCACGGTATCTGCAAGCGCACATGCTTACGCACTCGACGGTGCGCAAATTTGCGTGCTTAATCTGTGGCAACGCTTACAAGACGAACGGGGAGCTAAAGAAGCACAACAAGAACAAGCACGGGCTTGACGTTGTggaggaggaggaggaggTGCGCGAGCTGATCATTGATTCGGAAGATCAGTCGTTCATTGTGGAGTATGTTTAA
Protein Sequence: MSAECSDSNSDRKLLLYRDLFCRICLQYSKGALIPIDAEIKKTTLLDMFIQLTTFEIDHNDAYPRFMCEQCVSKLTLAYSIREEFISQTDLLLKLVAQKQIIKYYEQFPLDENASVPAPKTQPSEYAPFRDVKPPKAAKPKGSSITAVRPENLVIPENEKHESMEVLEEAEDLVREEYLNETSLPSQNVSSLTDFSKDWESSSTTTSLDEDDWSYSLNPITPQKLEELKPVKPVRKKYPSSTRKRVKAEAGNQEKKQRKNQYSTTTCYICDTQHETIAERDDHFRHHIHMLPYECTECVADPTPEDSPTKEESQPADTTTTAPTTKHIVLRSVIQLNSHMMMHGFPHKCEHCYRRFTTTYLLNHHLWNYHQHSKEGLTCEWCGKRYYSRRPFQEHVRRHRHSVTERFKCVTCGRAFGSNALLRRHEMVHTGERSHKCTYCSRMFSRRCNLLDHLRLHTGERCHKCNECPQSFNSKASLEKHQRNYHSDLAVVPPRGDRNIYTLQADGTRLYRCKHEGCTFTSVSSTTMTQHRLRHNKPCVCEECGQRFVAPKYSYATPPQTTVLQRFCRLCLREHPFLLPFNATLEDTTLADMLERLLGSFKLKQTPNLPNGVCSHCVTKLNYAYQVQKELVRNEQRLRHYHRGGNVLERLFEYQTKITATKEGRVVNRMVAQHGDGLLTETISVEASVDAPDMREEDTRAAAIAKTLVPTGGWAVIACDCPAKPVAVTRRPVKPVRAVKRTLRSRRVLRQAIDAGNPTALNASPIDPCKCYICNTVLESEASCRTHLAMHVDMLPHICPDCGTPDEEGATNRPITSLAMLQRHYRTHSYPLKCPHCPQRFLKYTSVYSHVRYRHELFDSPEGFTCDVCGVTMQYRPSFMYHMRIHYHEQMGTFRCQYCDRVFGTRARLERHERAHTGERPFACHQCPKTFAHRGQLATHTARHNNERGHQCAQCGKAFFNKAMLRQHLASHETLETRKTSSVAKVRQRPCSYAGCTHVAHTYQAYYMHRLRHEMAHRCDECGRRFAQHGTLTEGEDDEGDEQKIVLMNAEDPIMDVILEESAPQGILINEDIELDGTYEEEIETVEESIVVEQPIVSIGIDEVTKQEYIIDMEKVDTRRPSLCISATSSAEATSGDFCRICLLKRPHLTSLMERIDGVMIPEMLYKLCGRQIEVQDNYPRSICQRCLCQLDCAYKFLNEFHQQDERLRSFYWSGSVVKRLQEYQPEGAKTVEKRMAELVSRNTALFTPPAKEMCHKQTNTKRHPKLVDVGTVTDKVLEVDMSLIKTESADEDILLEQYVMEDENEDRYLDYTDDQDSSSVNEQHLVSMKIDVLRGLDATEPHSSEMKTRRKKEKQEPVSQRTPRQREAKSRHALMQKVKQPSLPSTPSETDDQGTEEDFKELFEDSDAADAKEEEEEEEEEEKYADEVQEDNDEGQEIEPLDPLRCYICEQTEETEAMLEQHLDMHSLMLPFECKSCKVEGAPAPLDEHKVEKHLRGAELEAFLARKEKQRTVKRPASLKDKECPYPDCDYVANTYGAMYVHKRTKHQPVHRCDMCNKSFAFLNQLNMHMKLHTGEKPFQCEICGRSFRRSFSYREHMEMHVTDATYNCPTCNKSFKRPRYLQAHMLTHSTVRKFACLICGNAYKTNGELKKHNKNKHGLDVVEEEEEVRELIIDSEDQSFIVEYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -