Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB671743:522230-527052[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.17 10 6.2 4.5 3 23 357 378 355 378 0.92

2 11 1.6e-05 0.00095 18.9 0.4 1 23 383 405 383 405 0.98

3 11 0.0007 0.043 13.7 3.1 1 23 411 433 411 433 0.97

4 11 1.3e-05 0.00078 19.2 1.6 1 23 439 461 439 461 0.98

5 11 5.2e-05 0.0032 17.3 0.5 1 23 467 489 467 489 0.97

6 11 8.2e-09 5e-07 29.2 0.2 1 23 495 517 495 517 0.99

7 11 3e-05 0.0019 18.0 2.3 1 23 523 545 523 545 0.99

8 11 7.9e-06 0.00048 19.8 0.7 3 23 556 576 555 576 0.98

9 11 0.00013 0.0078 16.0 1.5 3 23 584 604 582 604 0.98

10 11 0.00012 0.0073 16.1 0.5 1 23 610 632 610 632 0.94

11 11 2e-05 0.0012 18.6 2.5 1 23 638 660 638 660 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.17	10	6.2	4.5	3	23	357	378	355	378	0.92
2	11	1.6e-05	0.00095	18.9	0.4	1	23	383	405	383	405	0.98
3	11	0.0007	0.043	13.7	3.1	1	23	411	433	411	433	0.97
4	11	1.3e-05	0.00078	19.2	1.6	1	23	439	461	439	461	0.98
5	11	5.2e-05	0.0032	17.3	0.5	1	23	467	489	467	489	0.97
6	11	8.2e-09	5e-07	29.2	0.2	1	23	495	517	495	517	0.99
7	11	3e-05	0.0019	18.0	2.3	1	23	523	545	523	545	0.99
8	11	7.9e-06	0.00048	19.8	0.7	3	23	556	576	555	576	0.98
9	11	0.00013	0.0078	16.0	1.5	3	23	584	604	582	604	0.98
10	11	0.00012	0.0073	16.1	0.5	1	23	610	632	610	632	0.94
11	11	2e-05	0.0012	18.6	2.5	1	23	638	660	638	660	0.99

Sequence Information

Coding Sequence: ATGTACAAGTCTTTCAGCACTAAGGCGGATTCAAAAGCAGTTGCAACAAAACTTGCGTCGATAAAAACTGAAATATCACGAACGGCGAATGCTACAAGTGCCTCCGATCCAAAAATAATCTATTTAGACCGAGTGTGTCGAACGTGCTTGATGGAGAGGGAAAAAGACCAGCTTAAAGATCTGTTCCAATGTCGTTTGGCGGAAACTATCATGAGCTGTACCCGTATTATGGTAGCTAATGCGTTAGTCACGTTTCCCCTCAAGATGAGCACTCACGTGGCTGTGACCGAATCCGATGGTCTTCCGTGCCATATCTGTACAAGTTGTTGTGAAGAATTGGAAAGATGCTTCAACTTTCAGCAAATGACCAAAGCATCAGATGCCACCATACGATCGCTAATCGAAAAATCTGTCGTTATCAAACAAGACAGCGAAACTAAGTATGAAGTGTTGAATGTGGTGCTAACCGATTCGCAAGGTAACGCGGAAGCGTCCGCCATTGTTGTGCCTCTTGAGGAACTTCGATTTCAGCTTATAAATTCAAACAATTCGGTAGAACAGGAGCTGCAGAACATCAAGCCGGATAGCGAGTCGGAGAAATCGATCGAAAACTGCCCACTTGCAATTGAAAGCAGCGTTAAAGGTACCGACGATTGCCCACTAAATATTAATCCTGTTAGCTTGGCAAACGAGTCGACAGCTACGGTCCCACCGAACAATGATGCCTCCGAGCATCTTTCGGCAGCACGAGAATCTACCATTCTTAGGAACTTGAAGCAGGAGCTTTCAGAATTCATCGGAAGCAACTGCACTGCCATCTCGAAAGAAGTAGAGATCGTAGACGTACATGAGGACGACGAGATGATCAACGTGGACTATCTGAAAGATGCACTCACTGAGGAGTACATTCAAATCATGGAAACTCAGCTTGCACCCACATTGCCCAGCAGCAAGGAGGAACAGCTAGAGCAAGAGCATCTGCACAATCTCATTCACGCTTCGATGGAAGCGGAGGAACCTCGCGATAGGCAGCAAAGGGAGCATGCTAACGAAAGCGACACAATGCATTGCAAAATATGTGATGTACAATTTAATAAACGCAGGTTGTACTGGAAACACGTCCACCAAAAGCACTCCGAGAAACGGTTCGAATGTCAGCTGTGTTCGAAAAAATTTGCGGAAAATGCTGCCCTGAAAAGTCACATGCTTCGCCACACAGGAGAGAAAACGCACGTGTGCGATGTTTGCAATGCACGTTTCTACGAAAAAACTCTTCTAAACTTACATATGCGCCATCACTCAGGTTTGCGACCATACGCTTGTAAGCTGTGTGATAAACGTTTTACTACTCGAAGCATTCTCAACACgcaccaaaaggtacatactgatccgcggccccacgtgtgcgatgtttgccagaaaggattcaaattgtcttggcagctcaaggcacacggccgaattcacacgaacgaaaagccctacgaatgcccttactgcccaaaacgattcaatcagaacggcaatctcgtagtgcacatacgaacgcactccggagagaaaccattcaaatgtaaaatctgtgaaaaagcgtatcCAAGCCAAGGAGAACTAAGGTGCCATATGCGAAAACACACCGGTGAGGAAAAAGCAAAGAAGGTCGCGTGCTCCATATGCAGCAAAGCGTTTTCCGCCAATCACGATTTGCTCATCCACATGCGAACACACACAAAGGAAAAACCGTACGGATGTTCGGTTTGCGAAAAACGTTTTATGCTACGCGTGCATCTCACCGTTCATATGCGGTCCCACACAGGCGAAAAACCGTTCGCTTGTAGTTTGTGCGAAAAAGCATTCCCTACCAATTATCAATTAAAAATGCACAGCTATGTACATACGGGAGAGAAAAATTATTCATGTGACGTGTGTAACCGAAAATTCAGCAGCTCTGCTAACCGCAACACTCATCGTAAGACACACGATCGAAAGAAAAATTAG
Protein Sequence: MYKSFSTKADSKAVATKLASIKTEISRTANATSASDPKIIYLDRVCRTCLMEREKDQLKDLFQCRLAETIMSCTRIMVANALVTFPLKMSTHVAVTESDGLPCHICTSCCEELERCFNFQQMTKASDATIRSLIEKSVVIKQDSETKYEVLNVVLTDSQGNAEASAIVVPLEELRFQLINSNNSVEQELQNIKPDSESEKSIENCPLAIESSVKGTDDCPLNINPVSLANESTATVPPNNDASEHLSAARESTILRNLKQELSEFIGSNCTAISKEVEIVDVHEDDEMINVDYLKDALTEEYIQIMETQLAPTLPSSKEEQLEQEHLHNLIHASMEAEEPRDRQQREHANESDTMHCKICDVQFNKRRLYWKHVHQKHSEKRFECQLCSKKFAENAALKSHMLRHTGEKTHVCDVCNARFYEKTLLNLHMRHHSGLRPYACKLCDKRFTTRSILNTHQKVHTDPRPHVCDVCQKGFKLSWQLKAHGRIHTNEKPYECPYCPKRFNQNGNLVVHIRTHSGEKPFKCKICEKAYPSQGELRCHMRKHTGEEKAKKVACSICSKAFSANHDLLIHMRTHTKEKPYGCSVCEKRFMLRVHLTVHMRSHTGEKPFACSLCEKAFPTNYQLKMHSYVHTGEKNYSCDVCNRKFSSSANRNTHRKTHDRKKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -