Basic Information

Insect: Anopheles epiroticus
Gene Symbol: ZNF219
Assembly: GCA_000349105.1
Location: KB671528:133507-139537[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.7e-05 0.0016 18.2 0.6 1 23 131 153 131 153 0.99

2 11 7.2e-05 0.0044 16.8 2.8 1 23 159 182 159 182 0.96

3 11 1.6e-06 9.9e-05 22.0 0.4 1 23 188 210 188 210 0.99

4 11 4.6e-06 0.00028 20.6 0.2 1 23 216 238 216 238 0.98

5 11 0.0063 0.38 10.7 3.0 1 23 244 266 244 266 0.98

6 11 7e-06 0.00043 20.0 3.1 1 20 272 291 272 295 0.95

7 11 0.022 1.3 9.0 5.5 1 23 301 321 301 321 0.97

8 11 8.5e-06 0.00052 19.7 0.1 3 23 329 349 328 349 0.98

9 11 1.2e-05 0.00073 19.3 1.1 1 23 355 377 355 377 0.99

10 11 2.6e-05 0.0016 18.2 0.7 1 23 383 406 383 406 0.97

11 11 0.012 0.73 9.8 1.2 1 20 412 431 412 432 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.7e-05	0.0016	18.2	0.6	1	23	131	153	131	153	0.99
2	11	7.2e-05	0.0044	16.8	2.8	1	23	159	182	159	182	0.96
3	11	1.6e-06	9.9e-05	22.0	0.4	1	23	188	210	188	210	0.99
4	11	4.6e-06	0.00028	20.6	0.2	1	23	216	238	216	238	0.98
5	11	0.0063	0.38	10.7	3.0	1	23	244	266	244	266	0.98
6	11	7e-06	0.00043	20.0	3.1	1	20	272	291	272	295	0.95
7	11	0.022	1.3	9.0	5.5	1	23	301	321	301	321	0.97
8	11	8.5e-06	0.00052	19.7	0.1	3	23	329	349	328	349	0.98
9	11	1.2e-05	0.00073	19.3	1.1	1	23	355	377	355	377	0.99
10	11	2.6e-05	0.0016	18.2	0.7	1	23	383	406	383	406	0.97
11	11	0.012	0.73	9.8	1.2	1	20	412	431	412	432	0.92

Sequence Information

Coding Sequence: ATGAAGAAATCAACGCGCCAAACTCGAATGTCCCGGTACGTGGGTAAGCACTCGCCTAAGATCGCGACACCGGAAGAAAGCAACAATAACATCAAACCAACCAGCAAAAAACCAATCGAAACTGTCGCTACAATAGTCAGTGGTGATGACGAGATGTCGATGGTGGACCTTTCTTCTTACATTGCGGAAAAACCGATTACATACGACGAATCGTCCGTAGACGATGAGGAGGATGACAAATCGGTTGTGAAGAAGCTGGTGAACGCGAGTGACGATACGGCAGAGGGAAGAGATGGTGTAGAGTCTGGTAGCGGAACTGATGCGACATTTTCATCTACTGGTGGGTCTTCGTCATCGAAACGTGGACGAAAACGACGAGAGCGGAAATTATATCAGTGCGAGGTGTGCCAAAAGGACTTTATGGGCACGAACGATTTGCGCAAGCATTTGCGAATACATAATGATGAACGGCCGTATCCATGTCCACACTGCAAAAACCGCTTCCGACAGGCGGGATGCCTGAAAAATCACATTGCTTCACAACACGGTACGGATGAGCAATATACGTGCGATCTGTGCGGTAAGTCATTTCCGATCAAGGAACGGCTACGGTTACACATGCGCATCCATACCGGTGAAAAACCATACAGTTGTTCGCTTTGTCCAAAAACCTTCGCGCGTGGCGGACAGCTGACGCAGCATCTTGCTACTCATAATGGCGTGAAGAAGCACAAATGCGATCAATGCACCGCTGCTTTCTCCTGTGCAGCTAACCTGAAGATGCACCTTAAAAGTCATATGGATATTCGCGACTACACGTGCCATATCTGCGGACGAGGATTCTATCGACCAGATGCACTGAAAAAACATTTGCTTTGTTATCATGCTAATCTGAAGGCATTTCATTGCAATATATGCAATAAAATGTTTAAGGGACACTTGCCACAACACATGCGAACGCATATGAAGGTACGTCCTCATGGTTGTGCAGTGTGCGGTTCGGTATTCTCCCAACGATCACAGCTGATCGTGCACCAGCGAATTCATAGCGGTGAACGCCCTTATCGCTGTCAGGTTTGCTGGCAAGCATTTGCACACTCAAGTGTGCTGAAGTTGCACATCCGAAAGCATACTGGCGAAAAACCATTTGAGTGCCCACTTTGTGTATCAAGTTTCTCGCAGCTACCACATTTAAAGAAGCATATGCTATCTATCCATCAGCAGGACAAATCTTACCTTTGTCAAAAGTGCAAAGAGTTTTTCAAAACTAAGATGGACTACCAACTGCACGTTACAGCTTGCTACAAGGACCCGGCAGCTTTGAAGAATCTCGACAATATGATGGATCCAATGTACCGACCGACCGAAAACAACGGGATTGACCCACCCATGACTATCTCTCGAATGCGATTTCTAGTGGCCATTTTGCTaaaaaaaaTTTCTAACGATGATCGTTTGAAGGAGCTGGGCTTCGATAAGCGATTGATTGACAATGTACTAATTGATTCATTGAAATGTGCTGGACGCAAGGTATGCGATGACAAATCGTACGATCCACTGGAACGATTGAAGTTAAATGTGCAAGAGCTTCTCGAGTGGACAGTACCATCCAATTACATGGAAGAGTTTCGCGGAGCGAATCGCAGTACTGAAGAGTTACTTGAAGAATTAACAAACTAA
Protein Sequence: MKKSTRQTRMSRYVGKHSPKIATPEESNNNIKPTSKKPIETVATIVSGDDEMSMVDLSSYIAEKPITYDESSVDDEEDDKSVVKKLVNASDDTAEGRDGVESGSGTDATFSSTGGSSSSKRGRKRRERKLYQCEVCQKDFMGTNDLRKHLRIHNDERPYPCPHCKNRFRQAGCLKNHIASQHGTDEQYTCDLCGKSFPIKERLRLHMRIHTGEKPYSCSLCPKTFARGGQLTQHLATHNGVKKHKCDQCTAAFSCAANLKMHLKSHMDIRDYTCHICGRGFYRPDALKKHLLCYHANLKAFHCNICNKMFKGHLPQHMRTHMKVRPHGCAVCGSVFSQRSQLIVHQRIHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFECPLCVSSFSQLPHLKKHMLSIHQQDKSYLCQKCKEFFKTKMDYQLHVTACYKDPAALKNLDNMMDPMYRPTENNGIDPPMTISRMRFLVAILLKKISNDDRLKELGFDKRLIDNVLIDSLKCAGRKVCDDKSYDPLERLKLNVQELLEWTVPSNYMEEFRGANRSTEELLEELTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100454;
90% Identity: iTF_00105288;
80% Identity: -