Basic Information

Insect: Anopheles epiroticus
Gene Symbol: -
Assembly: GCA_000349105.1
Location: KB671058:143443-147831[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.26 16 5.6 0.7 8 23 225 241 208 241 0.73

2 18 8.3e-05 0.0051 16.6 1.2 2 23 250 271 249 271 0.96

3 18 5.7e-05 0.0035 17.2 2.0 1 23 302 325 302 325 0.97

4 18 5.8 3.6e+02 1.4 0.1 2 11 331 340 330 344 0.89

5 18 1.2e-05 0.00071 19.3 1.4 1 23 353 375 353 375 0.97

6 18 7.5e-05 0.0046 16.8 0.4 2 23 386 408 385 408 0.96

7 18 2.6e-05 0.0016 18.2 0.4 3 20 416 433 415 435 0.93

8 18 5e-06 0.00031 20.5 0.9 1 23 442 464 442 464 0.98

9 18 1.1e-05 0.00065 19.4 2.7 1 23 470 493 470 493 0.98

10 18 8.9 5.4e+02 0.8 0.8 9 23 745 760 727 760 0.74

11 18 0.017 1.1 9.3 0.3 2 23 768 789 767 789 0.96

12 18 8.2e-05 0.005 16.6 4.0 1 23 820 843 820 843 0.97

13 18 0.027 1.7 8.7 0.4 3 23 850 870 848 870 0.94

14 18 5e-05 0.0031 17.3 2.2 1 23 874 896 874 896 0.97

15 18 0.012 0.74 9.8 0.1 2 23 907 929 906 929 0.95

16 18 0.0022 0.13 12.2 2.2 2 20 936 954 935 956 0.94

17 18 9.9e-08 6.1e-06 25.8 1.3 1 23 965 987 965 987 0.98

18 18 0.0038 0.23 11.4 5.1 1 23 993 1016 993 1016 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.26	16	5.6	0.7	8	23	225	241	208	241	0.73
2	18	8.3e-05	0.0051	16.6	1.2	2	23	250	271	249	271	0.96
3	18	5.7e-05	0.0035	17.2	2.0	1	23	302	325	302	325	0.97
4	18	5.8	3.6e+02	1.4	0.1	2	11	331	340	330	344	0.89
5	18	1.2e-05	0.00071	19.3	1.4	1	23	353	375	353	375	0.97
6	18	7.5e-05	0.0046	16.8	0.4	2	23	386	408	385	408	0.96
7	18	2.6e-05	0.0016	18.2	0.4	3	20	416	433	415	435	0.93
8	18	5e-06	0.00031	20.5	0.9	1	23	442	464	442	464	0.98
9	18	1.1e-05	0.00065	19.4	2.7	1	23	470	493	470	493	0.98
10	18	8.9	5.4e+02	0.8	0.8	9	23	745	760	727	760	0.74
11	18	0.017	1.1	9.3	0.3	2	23	768	789	767	789	0.96
12	18	8.2e-05	0.005	16.6	4.0	1	23	820	843	820	843	0.97
13	18	0.027	1.7	8.7	0.4	3	23	850	870	848	870	0.94
14	18	5e-05	0.0031	17.3	2.2	1	23	874	896	874	896	0.97
15	18	0.012	0.74	9.8	0.1	2	23	907	929	906	929	0.95
16	18	0.0022	0.13	12.2	2.2	2	20	936	954	935	956	0.94
17	18	9.9e-08	6.1e-06	25.8	1.3	1	23	965	987	965	987	0.98
18	18	0.0038	0.23	11.4	5.1	1	23	993	1016	993	1016	0.96

Sequence Information

Coding Sequence: ATGGCGTGTGTGAAGATGGAAGACAATCCTGGTGGAGCAGGAAGCAAAGAGTCTGTGTGTGATGTGTGTCTTCGCAGCAGTGGCGCTTGCTTCAGCAAAACGGATCCCATTTTCCGCGGCAAAGATGTGCTGGCGATGATTGCACGGTATCTGGATATGAATATCATACCAACGCTCGTCTGTCAGTGCTGTTGGCGCAAGCTGGACGAGTTCGATGAGTTCTACAGAATGGTTAGCGAGCAGCACAATAACTTCATCGATACGCTCAAACCGAGCTCTACGCTCGCGGACACCCGGGAGAACAGTCCCGCAGGAAAACGGGAGGAACAAGTGTTTGGGATGGAATTTGTGGAGATTAAACACGAACCATTGATGGAGGATATGAATTTGAGTGTAAAGGAGGAAAAGGAACCACTTCCGGAGTGTGACGACTACGATAAGCTATCACCCGAACGGTCAATGGCGGAGGAAGATGATGAAGACGATCCGGTGGATGATGATACGCACTCCCTTTCATCGAGCGATAGTGAATATTCTTCCGGACGGCGGAATGGCGGGAAGGTATCAGCTGCCAAGCGAGAGCCCGTGGTCGATACCGAGCTGTTGGAGTTTTACAAACGGTTGGTGTGCGAGATTTGCGATGCCGAACGGATGCTGGCTGGTGAACCGTCGATCGAGTACAGCAATCTGCGAGAGTTTAACAAGCACATGCGAAAAGCACACGATAAGGCAGGCGGGTGCAGAATCAAGTGTCCGATGTGCGAAAAGAAATTCCGTTACCGGAGGCAGCTGCTGGAACACCGGGATATGCACCTAAATCCGGATCAATTTCGTTGTGTGGTATGCGAGGAGGTGCATCAGAATATGGTGCAGCACATGCGGAACAAACACCAAGAGCGAACGTACTGCTGTGAGGAGTGTGGGAAGCGGTTCCCGTTCAAGGCTCGCCTAACGGCTCATGTGAAGAAAATGCACACCTCCAAGGACGTTGTATGTGATCAGTGTCAGAAAAGATACACAATAGACGACCATAAGCGGGCCGTTCACGAGTCGAAGTACATCTGTGAACACTGTCCGCGTACGTTCAAGTCGCGTATCTCACTGTCGCAACACATGGAAGAACACGTGGAGGGGTTGCGCAAGTCGGTGGCCGTCACCTGTGATAAGTGTGGCGTGGTGCTGCGCGACAAGTACACTCTTCAGACGCACATCAAGCGAATGCACACAGAACATCCGCCCGCTAGCTGTGGATCGTGCGGTAAGGTGTTCAAATCGAAACACAGCCTCAACGCTCATATGGCAAACGTGTGCACCGAGCGCACGTTTCCTTGTCCGATCTGTGAGAAGCAGTTTAAAAAGAAGATTAAACTGACGGAACACATGACGACGCACACGAAGAGTGTGCTCTACCAGTGTCCGTACTGTTCAAAGACTTTCAGCTTTGAGACGCAGTTGTACACACACCGGAAGCGGGCCCACTACGAGCAGTGGCTCGAGATGCAGCAAAAGCGGAAGGAGGGCGTACGCGAGACGCAAGAGTATGCTGCAATGGCCACAGAAGCAAGATGCGAAGTGTGCTTCTTCACGGTGGACGACTTTTGTAAGAAAGTGTTCGCGGAGGAAAACAAACATATTGTTGAAATCGTAGCGAAGCATTTGTGGTTTGAGATACCACCGGCATTAAAGGATGCATCAATGTGCAGGAGATGCTGGAATGCATTGGAAGGTTTTCACCATTTTTATTGTGAAATTGAGAGAGCACGACGGCAAGAACTAACATCAGTTATGATTGACGTACAGCAGCAGGCAGAAGTTCCTATTGCTTGTGAAAGCTCGGAACTAGCCCACAATACAGAATTTTTCGAGGTGAAGATAGAAGAACCATTCGAATCGGCGAACATGCTTGAGCAGGAAAGCTGCGACGAGCAACCGTTGCAGTGTGAGTTTGTGAAGTGTGAAGAACTGAATGAACTTCAGGATCCGACGGCGCCATCGTCGGAAGAGGACGTGCCGCATGAAGGCAGCAGGTCGGACTCGTCGTCCACAGACGGTAGAAAGAGAGGTGGGCGCGAGAAGAAACCCAAACCGGGGCTGCAAATAAGCGACAGTGAGACGAAGCTTTGTAAGGCGGCCGCTCAGAAGGAGGAAGATGAAAGTTTGCACAACTTCTACAAACGGATCGTCTGCGAGGTGTGCGATCAGCAGCGCATGTTGGTGGGTGAGCCACAGATCGACTTTGGCACGTGGCGAGCACTGTTGCGCCACACGAAAGAGGTACACAAGCACGACAAGGTGTTCGTTAAGTGCCCGGTGTGCGAGATGAAGATGCGAACGAAGCAAACCCTGCTGCAGCACATGGATTGGCACGAAAATCCGGAAAACTATCGCTGTGAGCTGTGTGGCGAGAAGCATCAAAACATGAAGGAACACATTCAGAACAAGCACCAGGAGAGACAGTTCTGTTGCGATGTTTGTGGGAAAAAGTTTCCGTTCAAGAAGAGGCTTACTGTGCATATGAAAAAGATGCACGTAGAGAAGGACATCATTTGCGACCAGTGCCAGAAACCCTTCACAAAGTACACAATCGAAGACCACAAACGTTCGGTGCATTCGGCCCGATTTGTCTGCGAGCATTGCCCGAAAACGTTTAACAGTCGCTTCCGGTTGCTGCAGCACATGGAGGAGCACGATGAAAGCTTGCGTAATTCCACCTCCGTACCGTGCACCATATGTGGACAGGTGATGCGTGACAAGTACATCCTTACGAGACACATCAAGCTGATGCACACGGTACAACCGGCGGTCAGTTGTACCACCTGTGGGAAAACGTTCAAATGCAAGCGCAACCTTTCCGTGCACATGACGAACGTATGCATGGAGCCGACGCGCCTGTATCCGTGCACCATCTGTGGGAAGGAGTTTCGGCGTAAGAACAAACTCAAGGAGCACATGTCGACGCACACCGGCAAACCGCTGTACATGTGTTCCTTCTGCCCGGAAACATTCCGCCAGGATACGCACCTGTACCACCATCGGAAGAATGCGCACTACGAACGATGGTTGGAGATGCAGCAGCAGCGCAAGGAGGGCGTACGTTTCAAATTGACTGAACTGCCGTAG
Protein Sequence: MACVKMEDNPGGAGSKESVCDVCLRSSGACFSKTDPIFRGKDVLAMIARYLDMNIIPTLVCQCCWRKLDEFDEFYRMVSEQHNNFIDTLKPSSTLADTRENSPAGKREEQVFGMEFVEIKHEPLMEDMNLSVKEEKEPLPECDDYDKLSPERSMAEEDDEDDPVDDDTHSLSSSDSEYSSGRRNGGKVSAAKREPVVDTELLEFYKRLVCEICDAERMLAGEPSIEYSNLREFNKHMRKAHDKAGGCRIKCPMCEKKFRYRRQLLEHRDMHLNPDQFRCVVCEEVHQNMVQHMRNKHQERTYCCEECGKRFPFKARLTAHVKKMHTSKDVVCDQCQKRYTIDDHKRAVHESKYICEHCPRTFKSRISLSQHMEEHVEGLRKSVAVTCDKCGVVLRDKYTLQTHIKRMHTEHPPASCGSCGKVFKSKHSLNAHMANVCTERTFPCPICEKQFKKKIKLTEHMTTHTKSVLYQCPYCSKTFSFETQLYTHRKRAHYEQWLEMQQKRKEGVRETQEYAAMATEARCEVCFFTVDDFCKKVFAEENKHIVEIVAKHLWFEIPPALKDASMCRRCWNALEGFHHFYCEIERARRQELTSVMIDVQQQAEVPIACESSELAHNTEFFEVKIEEPFESANMLEQESCDEQPLQCEFVKCEELNELQDPTAPSSEEDVPHEGSRSDSSSTDGRKRGGREKKPKPGLQISDSETKLCKAAAQKEEDESLHNFYKRIVCEVCDQQRMLVGEPQIDFGTWRALLRHTKEVHKHDKVFVKCPVCEMKMRTKQTLLQHMDWHENPENYRCELCGEKHQNMKEHIQNKHQERQFCCDVCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHTVQPAVSCTTCGKTFKCKRNLSVHMTNVCMEPTRLYPCTICGKEFRRKNKLKEHMSTHTGKPLYMCSFCPETFRQDTHLYHHRKNAHYERWLEMQQQRKEGVRFKLTELP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -