Basic Information

Insect: Anopheles epiroticus
Gene Symbol: Zfy2
Assembly: GCA_000349105.1
Location: KB670536:262-5961[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.88 54 4.0 2.1 3 23 63 80 62 80 0.91

2 19 0.00065 0.04 13.8 0.1 3 23 88 109 86 109 0.97

3 19 4.7e-05 0.0028 17.4 1.1 2 23 116 138 115 138 0.97

4 19 0.0038 0.23 11.4 1.3 1 23 144 167 144 167 0.98

5 19 0.091 5.6 7.1 0.7 2 14 174 186 174 188 0.90

6 19 4 2.4e+02 1.9 0.9 3 23 478 495 477 497 0.76

7 19 0.00057 0.035 14.0 0.2 1 23 501 524 501 524 0.95

8 19 0.00086 0.053 13.4 2.7 2 23 531 553 530 553 0.97

9 19 4.9e-06 0.0003 20.5 0.9 3 23 561 582 559 582 0.97

10 19 9.1e-06 0.00056 19.7 1.9 1 23 588 610 588 610 0.98

11 19 0.00015 0.0091 15.8 3.5 1 23 616 638 616 638 0.98

12 19 4.1e-06 0.00025 20.7 2.1 1 23 643 666 643 666 0.98

13 19 7.2 4.4e+02 1.1 0.1 3 12 896 905 895 915 0.78

14 19 0.0074 0.45 10.5 1.8 3 23 921 942 919 942 0.96

15 19 9.6e-05 0.0059 16.4 1.9 2 23 949 971 948 971 0.96

16 19 0.00033 0.02 14.8 4.2 2 23 978 1000 977 1000 0.96

17 19 8e-06 0.00049 19.8 1.4 1 23 1005 1027 1005 1027 0.97

18 19 0.0094 0.58 10.2 2.9 1 23 1033 1055 1033 1055 0.90

19 19 6.9e-05 0.0042 16.9 2.4 1 23 1060 1083 1060 1083 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.88	54	4.0	2.1	3	23	63	80	62	80	0.91
2	19	0.00065	0.04	13.8	0.1	3	23	88	109	86	109	0.97
3	19	4.7e-05	0.0028	17.4	1.1	2	23	116	138	115	138	0.97
4	19	0.0038	0.23	11.4	1.3	1	23	144	167	144	167	0.98
5	19	0.091	5.6	7.1	0.7	2	14	174	186	174	188	0.90
6	19	4	2.4e+02	1.9	0.9	3	23	478	495	477	497	0.76
7	19	0.00057	0.035	14.0	0.2	1	23	501	524	501	524	0.95
8	19	0.00086	0.053	13.4	2.7	2	23	531	553	530	553	0.97
9	19	4.9e-06	0.0003	20.5	0.9	3	23	561	582	559	582	0.97
10	19	9.1e-06	0.00056	19.7	1.9	1	23	588	610	588	610	0.98
11	19	0.00015	0.0091	15.8	3.5	1	23	616	638	616	638	0.98
12	19	4.1e-06	0.00025	20.7	2.1	1	23	643	666	643	666	0.98
13	19	7.2	4.4e+02	1.1	0.1	3	12	896	905	895	915	0.78
14	19	0.0074	0.45	10.5	1.8	3	23	921	942	919	942	0.96
15	19	9.6e-05	0.0059	16.4	1.9	2	23	949	971	948	971	0.96
16	19	0.00033	0.02	14.8	4.2	2	23	978	1000	977	1000	0.96
17	19	8e-06	0.00049	19.8	1.4	1	23	1005	1027	1005	1027	0.97
18	19	0.0094	0.58	10.2	2.9	1	23	1033	1055	1033	1055	0.90
19	19	6.9e-05	0.0042	16.9	2.4	1	23	1060	1083	1060	1083	0.97

Sequence Information

Coding Sequence: ATGGACGACATTGAACCAGAAGCAACACCATCGAAACGAGCGTGTTCATTGAAAGGCATATGTAAACAGATCTCACCTACAGAAACGATAGTTACGGAAGAAACTAAAGAAGTGAACGCTGCTGAAGGTGCCAAAGCACTTGAAAACATAAACCCGGAAAACTGGCGACACTTTGGCAAACGAATGTGTGAAATTTGTGGTCAATCGGTTACCTGTTTGACACGACATCTTCGGAGCCACGCCAAGGAAGGTAAGTACGGCTGTCCGTACTGTACCGTCCAAATGTCGGACAGCTCCAACCTCTTGCGTCATATTCGATCGGTACATCTGAAAATTGTCGTCAAGACGTGCGAATTGTGTGGTAAAGGATTTGTACAATACAACACCTTCAACGATCATATGCGATCCAAGCACGGTATTGGAGAAAAGTACGAATGTAAAATATGCTTCAAAAATTATCTTCACCCGGCTGGGTTGAAGCAGCATCAACAGCGCGCGCACACTGACATAAGGAAAAACGAATGCGAGCTTTGCCACAAACGGTTCAAGAGCAAGTACGAGCAAGGAATCATTTTTGGACACGATTCGAAACTTAACAAGTGCACTTTTTCCATTCTCCTCACAGACGCGAACTGCGGGGTCATGCGCGAGTACATTCCGAAGAAAGACCATTCGCATGTAACCACTGCACAAAACGGTTCAAAAGCATCACATTTCCATGTCAACTCTGCAACAAGTCTTATCGGTACAAGTCTCAGCTCAACGTGCATATCCGGAAGTTTCATACGGAATCGAGTCAAGACAATGATGACGAATCTAATGGTTAGCACTCTGCGGGAAATAACCAATATCTGCCGGCTCTGCTTATGTGAGGAGCTGGAAATCTTAATTCCTACTAAGGATGTGCTCAACACTTCGCTTACCTCGGATGATGTCGAACGAATCACCGGTGTACGGATACCAACCGATGACAACGTACCTTACGTGATGTGTACTACTTGTAGAAATAGTTTAAGAAAATCAGTTGCCTTTCGAAACTCGTGCATTCGCAATGATCGGCTGTACATGCAACTGTTCTCGGAATACATTGATGATATTAGGACCGTAGCGGAAATAAGGCAAATTGCAGATACGATTGACCAACTGGATGTCGGTGATTTCGAGGAAAATAACTATGTAAATGATAAGCAAGAACTGTTAGCATCCCATGGCGAGGATTATTCTGAATTCGGCAATGAAGATGCCGAAGCTTGTGCGAGCGAAAAATCCAAAGAGAAGCCACTAAAAGTAGTGCGCTCAAATAAAAGCAGCAGGAAATCCCGCGCTAAAGTAGCTTTGGTTACAGAAACAAGCGAACAAAATGGCACGCAAAGTGGGAAACTGCTTAAAATCGCAAACTTGCAGGATTGGTCAAATTTTAGCAAACGATTATGTGAATTGTGTGGCCAGATGGTTACCAATTTCAAACGCCATCTCCTCAGTCACACTAAAAATGCCAAGTACGCCTGTCCACATTGTTCCGTGCAAATGACCGATAGCTCCAATCTCATACGTCACATCAATGCAGTCCATAAGAAAACGATCATCAAGACATGTGATATATGTAACCAAGGATTTACGCATTACAACAGCTACAATTCGCACTTGCGCATCAAGCATGGCAAAGGGGAAAAGTATGGATGCAAAATTTGCCCTAAAAAGTTCAACCACCCTAGTGGCTTAAGGGAACACATCAAACGGGTACACACCTTTGAAAGTAAATACGAATGCACACTTTGCCAAAAACGCTTTAAGACCAGCCGATCGTTACGATTACACGGACGCGTACATTCTGACAATCAACCGTACCCATGCAGCCACTGCCCAAAACGGTTCAAGAGTAGCTTCGCGCGCAATACGCACCAACTCACGCACACGGGTGTCATATTTTCCTGCGAGCTCTGCAAAAAGTCCTATCGGTACAAGTCCCTGCTCAGCATCCATATGCGCAAGGATCATCCCGAAGCAGTACGAAGCGCGGAAAACACGGAAGACCAGGACGAAGACATGCTCATCCCGGTAGCAAACGTACTGGATGCCCACATCACCATCGAAAACATAGAACGATTTACGGGCATTGTGATCGACCCGGTCGAAAATATTCTTCATGCCATATGCACCGATTGCGAAGCGCGATTGCAAAAGTGTGCAGCCTTCCGACGATCCTGCCTCAGAAATGATGCCTATCTACGTAAACTTTACTCAGAAGCAAGTGCTGAGGAAAGCGAAGCGGAAATAACTGACACTCACTTTATTGACTCGACTGATGATAAGGTGTATAACCGAACTGTTAAAAGACATTCTTCCTGCGGGAGTACTTCCCAGCAAAGTATGCCAGAGGTTGGTAAAAGGGTCACATCACAATTACAGGACTATCATGCTGCTAGTGCACCGGAGCCCCATCGAAACGGCACACCACTGCCGTTGGCCGCTGATAATGTTGAAGAAGAACTTTATTCGGCCAATTACATTGCGCCTGGTGAAGTGTCGGATGAAGACGAATACTTTTTAACCGATGACGATGAATACTTTGCGCCCGCCCGGAAATCAAAAAGTACCAAAGAAATGCAAATGGATAAGGAGTACATTTCCAACGAAATGTATCATTTGCTCGATCTTTCCAAATATCAGCGCCCGCGAACACTGTGCGAACTGTGCGGGAAGGCGGTAAGTGATATCGTGTCACACCTCTTAAGCCACAGGAAGGAAGCGATCTTTGGGTGTCCGCATTGTAACGTCCGTATGACGCACCAGGCAAATATGATGCGACACATACGAGAAGTACACGAGCGAAGGATCGTGAAATCATGCGACCTGTGTGGCAAGGGTTTCACGCACAATAATAGCTACATTTCGCACATGCTATCGCGTCATGGTATCGGGGAGAAGCAGGAGTGCAAACAGTGTAAACAGAAATTCAATCACAGGAGCGGTCTGCGGGAGCATATAAAGCGGTATCACAATATACAATTCTATGACTGTACGTTGTGCGATAAAACTTTTAAAATGAAGCGAGCACTTAAAACTCATCAGCTCGTGCATAGCTCCGAGAAACCGTACCCGTGTCCGAAGTGTCCGAAACGATTTAAGAGCAGCAAAGCTAGATCTTGCCATCTGCTAACCCACGCCGGTGTGCTCTTCAGTTGCACGCTGTGCAATAAATCCTATCGGTACAAGACGCTGCTCAATTTACACCGACGAAATGCGCACCCGGATGCAACCTTCAGCGAAGGGTAG
Protein Sequence: MDDIEPEATPSKRACSLKGICKQISPTETIVTEETKEVNAAEGAKALENINPENWRHFGKRMCEICGQSVTCLTRHLRSHAKEGKYGCPYCTVQMSDSSNLLRHIRSVHLKIVVKTCELCGKGFVQYNTFNDHMRSKHGIGEKYECKICFKNYLHPAGLKQHQQRAHTDIRKNECELCHKRFKSKYEQGIIFGHDSKLNKCTFSILLTDANCGVMREYIPKKDHSHVTTAQNGSKASHFHVNSATSLIGTSLSSTCISGSFIRNRVKTMMTNLMVSTLREITNICRLCLCEELEILIPTKDVLNTSLTSDDVERITGVRIPTDDNVPYVMCTTCRNSLRKSVAFRNSCIRNDRLYMQLFSEYIDDIRTVAEIRQIADTIDQLDVGDFEENNYVNDKQELLASHGEDYSEFGNEDAEACASEKSKEKPLKVVRSNKSSRKSRAKVALVTETSEQNGTQSGKLLKIANLQDWSNFSKRLCELCGQMVTNFKRHLLSHTKNAKYACPHCSVQMTDSSNLIRHINAVHKKTIIKTCDICNQGFTHYNSYNSHLRIKHGKGEKYGCKICPKKFNHPSGLREHIKRVHTFESKYECTLCQKRFKTSRSLRLHGRVHSDNQPYPCSHCPKRFKSSFARNTHQLTHTGVIFSCELCKKSYRYKSLLSIHMRKDHPEAVRSAENTEDQDEDMLIPVANVLDAHITIENIERFTGIVIDPVENILHAICTDCEARLQKCAAFRRSCLRNDAYLRKLYSEASAEESEAEITDTHFIDSTDDKVYNRTVKRHSSCGSTSQQSMPEVGKRVTSQLQDYHAASAPEPHRNGTPLPLAADNVEEELYSANYIAPGEVSDEDEYFLTDDDEYFAPARKSKSTKEMQMDKEYISNEMYHLLDLSKYQRPRTLCELCGKAVSDIVSHLLSHRKEAIFGCPHCNVRMTHQANMMRHIREVHERRIVKSCDLCGKGFTHNNSYISHMLSRHGIGEKQECKQCKQKFNHRSGLREHIKRYHNIQFYDCTLCDKTFKMKRALKTHQLVHSSEKPYPCPKCPKRFKSSKARSCHLLTHAGVLFSCTLCNKSYRYKTLLNLHRRNAHPDATFSEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -