Aepi000453.1
Basic Information
- Insect
- Anopheles epiroticus
- Gene Symbol
- -
- Assembly
- GCA_000349105.1
- Location
- KB671916:15753-27275[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 1.2 73 3.5 7.8 1 23 765 788 765 788 0.96 2 26 0.0016 0.1 12.6 3.8 1 23 794 816 794 816 0.99 3 26 0.02 1.2 9.1 0.9 1 23 860 883 860 883 0.96 4 26 0.00057 0.035 14.0 1.0 2 23 891 912 890 912 0.96 5 26 0.004 0.24 11.3 0.1 1 23 944 967 944 967 0.96 6 26 0.051 3.1 7.9 0.1 1 23 980 1003 980 1003 0.95 7 26 0.00014 0.0086 15.9 2.1 1 23 1069 1091 1069 1091 0.99 8 26 6.7e-05 0.0041 16.9 1.0 1 23 1178 1200 1178 1200 0.98 9 26 0.00048 0.03 14.2 3.5 1 23 1207 1229 1207 1229 0.98 10 26 8.4e-05 0.0051 16.6 0.9 1 23 1241 1264 1241 1264 0.94 11 26 9.7e-06 0.00059 19.6 0.9 1 23 1310 1332 1310 1332 0.98 12 26 3.2 2e+02 2.2 0.2 1 21 1346 1366 1346 1369 0.87 13 26 0.27 16 5.6 2.0 1 23 1451 1473 1451 1473 0.98 14 26 0.00089 0.055 13.4 1.1 2 23 1502 1523 1501 1523 0.98 15 26 0.0033 0.2 11.6 5.2 2 23 1554 1575 1553 1576 0.94 16 26 5e-05 0.003 17.3 5.3 1 23 1582 1604 1582 1604 0.98 17 26 3.9e-05 0.0024 17.7 0.3 1 23 1706 1728 1706 1728 0.99 18 26 0.13 8.2 6.5 11.3 2 23 1758 1779 1758 1780 0.95 19 26 0.049 3 7.9 7.6 1 23 1786 1808 1786 1809 0.95 20 26 0.00012 0.0071 16.2 0.8 1 23 1886 1908 1886 1908 0.98 21 26 0.00092 0.056 13.3 1.2 2 23 1943 1964 1942 1964 0.96 22 26 0.24 15 5.8 3.2 2 23 2180 2201 2179 2202 0.94 23 26 0.005 0.3 11.0 5.8 1 23 2208 2231 2208 2231 0.96 24 26 0.0028 0.17 11.8 0.4 3 23 2249 2270 2247 2270 0.92 25 26 0.00067 0.041 13.8 1.5 1 23 2276 2298 2276 2298 0.96 26 26 0.086 5.3 7.1 2.6 1 20 2307 2326 2307 2328 0.89
Sequence Information
- Coding Sequence
- ATGGAATGGGGCGACAGTTTGGCAACAGATCGCGTCATTGCCGGCGGTGGCGCTAGCGTCACTTCCGGCTCGCCGATGACACCGGGAATCGGGCATCATCTGCAGGGTGCGGCGGATGTTGGTGTCGTTGGACCGAACGCGTTCGTCACGCACGGTGGCTACGGCAATGAGACGGGCACGCAGAGCCACCAGCGCCGGATGATAGCGGCGGCCGGTGTAAACCAGTATGCCGGCGGTCGTGGTGTTGACGGGTCGGCAGGTACATCCGCTGCTGGATACTTCCACGATCAGCTTGGCCAGTCCGTGGTCGTCGGTACAACGATGGGACACTTCGTTGGAGTGGAAGCGACTGGTGCGGGTGCTTACGCAACGGCCGGTGTGGTGACGGGTGGCATGGTTCCCGGTGGCGGTGGCCGAACGGTCGGTCCAATGGTGGCAAGCCCGAACGCTGCCTCACCTACCGGCGTTCCTGGGATGGGTGGTGGCAACACGTATGGACATTCGACACCAACCCATGTGGCGTCGTATCTTCAGCAGCAAGGTTCCCCAAGCGGCATGCAGCGAATGAACGACATGAGCGCACTGCAAACACCCGTCGTTGTAGCCCAGCAACAACAACAGCAGCAGCAAATGGTGCCGGAACATCGGCGGGCCCAGCTACCGATGCATTCCGACTTTTCATCCGGGGCTTCCAGATCACCTTTTCCAGCAGCCGTGTCGCTTCCGTCGTCGAGCCCGTGTTTGGTTGACGCGACAGTTGCCGGTGGACAAATGGCCGCCTGCTCGAAACCTGCCGAGATGGTCATGAACAATGATCCGTTGAAAGCGGGCAACCAAATGCCGGTAATTGGTCAGCAGCAGCAACAGACAAGAGCATCGCAAATTGAGGCCACCGAAGAAACGGAGAATCTAGAAGACGTGCTAGACAGCAAGCTGCTTCCGGAAGCGAGTGGAATAAAGGCAAACAACATTCTCACCCAGTCGGGTGGCGCAAACGATGGGCAGTTGACACCGGCCATGGTGCTGCCGCACTCGACGGAGCAACCACGGAAGCGCTCCGTAAAGCATGTACGCTTTGTAGAACCGAACGAGGAGAACTCGTTCGATGGAATGCGACAATCGCGGGGTAACGTCGTTTCACCGCATCCGCTCGGTCTCGGCCATCGGAACGATGAGGAAGGCGATGAGGATGAGGAGGAGGAAGAAGAAGAGGACGACGATATGGATGAGCTGTCGTTGATGCAGAATCTGCCCCCGGTTGAGAGTTTACTGGTGGAAATGGATGAACCGCTGGACGATGAGGACAACGATGATGAGGAGGTGGAGATGGAAGACGACGATGACAATGGGGGTAGACGCCGGATGCCGGGACGTCGCCGAAGGGGAGGACACCATCTGTCGATGCATCGTACGCCACGTTCGAAGCACAGCGAGTCGATTGAGCTCGAGCTGGAACCGCTGCTGCCGGAGATCGAAATGGGCGAGGGTACTGCTGGGGACGAGAAGGGCGATGACAATCGGATTGCACCGGTGGCGCATGTGTGCCGGGTGTGCCTGTGTGACGAAAAGCCGGACGGCGAGGATGGCGAAACACGACCAATGGAGTCGCTCTACTGCACGGTGGTACCGGAGTACCAGTCGCGCAGCCTGTACTCGATCCTGGTGGCCGTGTGCCATCCGTTGCACCTTGGCAGCAATGCCGGCATGCCGGATCGGATATGCGGACCGTGCAAGACGAAGCTGCTGGCCGCGTACGAGCTGTACGATATGTGCCTGCGCAACGACGAGATGCTGCGCCGCAAGTACCAGGAAAAGCTGCTGCTTGCGTCCAGTGCGGCCGGTGGCGGTGGAGAGATGCGTCGCATCAAGAAGGAAAAGCTGGACAACAACGGCGTTGATGCGATCGGGGATGACGACGAGGACGACTATTACCGTGGCGGTACCGGTAAGCGCGGTCCCATGCGTATGAATGATCAAGATGATACATATCTGTACGATCGCCAGTACCCACTGCATGCGGCCAGCACGGCCGGCAGAAACTCTACCTTCGCAGCCTTGCCATCCCGTTTCCAGCAGCCGCAGCAGCAAGCGCACGGACGGTGGGGTAAATATCAGCGGCACCAATCGCACCTTTCCAACCAGATGCGCATCCAACATCAGGTAGCGAATGGTCCGGAAGCGTTGCGCCAGCTGCACGATGGCAGGAGTAAACAAGCGGCGAGCGGGCAGGCGGCCCGTTCGGCTGCTTCCTACGACTACAACTCATTCCACCGAGTGCTTCCGAACGGAAGCCACCAGTGTACGAAATGTATGCGTGAGTTCAAGTATCACAGCTACTACAAAAATCACTACATCAGTCAGCACGATCCGAGCAAACCGTTCAAGTGCCGTAAATGCCATTACACCTTCCTCACTGAACGGTGGTTAATCGTGCACATGCGTACCCACCTGGCGGCGGGTGACGTGATGTCGATGACGACGAGTGGCGGAGCGTCGATGGGAACCGATGCCGGCGCTATGGATTCGTTTGATTCATCGATGGATGGAAGCGTAGATCGTCGCAAGGGAGCGAGGGGCTTCGATTGTTACTACTGCGACATGACGTTCCCGGCACATGCTCTGCAAAAGCGTCACATGCTTTCCGCACACGCGGACAAGCACCGCGGCTTGGAGTGTCCTATTTGTCAGTGCCGGTTCGCTAACCAGTCCAGCTTCTTGTTGCATCTGCAAGAGCACAAGGATCAGAAGCGATTGCGGAAGACCATCAAGACGGAAGACGGTGGCAAAGGTGAGGAGGGTGCGGGTGGTGGTATGCAGGTGAAGCGGGAGTACAATTGCACCGTCTGTACGGCAATATTTGGCCGGGAGGTGCAACTGAACGAGCACATGCAGGAGCAACATCCGGACGCATTTTTGGCGATGCACACCGAGCTGGCCTTCATGTGTGGTGTCTGTTTGGCGGAGTTTAACGATCGTGCCGCGCTTGAAAATCACACAAGCAGCACGCACACCGAGGCGGAGCTGGCGGAAGCTGCGGCAAAGGGCATGTCGCAATCACCGGAAGCTGAGAGTGGGTCGCAAAATGAAGTCAAGCAGGAAGAGGAAAACAATGGAAACGGCACGAATGCCGAAATGACGACAAACGATGCTTCTGCGGAGGAAACCAATGGTACTGATAAACCACCCGAAGGGTGCTCCTTGGTGTACAAGTGTAAATTGTGCCAATCTCGCTTTGTTACGAAGAGTTCGCTGTCCTCGCATCTGGAAACGCATGTAGCTGCGATGAAGCGCGCGGCCACTAAGCGACCGTACAGCgaaacgggtgataatgacggtgcagatggggcagatggagcgatcgatgatgatgactacagtggtgaggaagatgatgatgatgatgaGCATTCGGCCGGTGGAGAGAAACGTTCGAAACGCTCCAAACTGCAGGACGAGGACGATGATACGACGGAAGAAATGCCGATCGATCCGGACGAGATTTCGTTCAATCCCGATACGGGTGAGCAGGTGTTTACGTGCCAGGTGTGCGGTAAGGTTATTAACACTGTATCCCAGTTCCGGCGGCACAAGCGTGTCCACTCGCCAAAGGGTCGCCCGTTTGAGTGTCACATCTGCTTCTATCGGTTTGCAATGAAGTACAGCTACACGGCGCACATGCTGCGGCACGAGCTCGGCTGCAATCCGACGCAACCAACGACTTACCGCTGCTCCAAGTGCTCTGAGACTTTCACGCGCCGGAAACTGCTCAGCCAGCACATTGCGGCCATGCACGGTCGCTGGTCAGACCCATCCGGCGGCAGTCCGATGTACGGTGTTTCGATGGGTGGTTCGTCTAGCATGTCCGCCCGTGCCGCAATGGGTCAGATAGCTGCTATGTCGACAGGTAGCGGCAGTGGTAGAGGCACACACACCTGTCCGATCTGTTCGGAGTCATTTACGCGCGAAAGCGTCCTTAATGGGCATATGAAAACGCACAATCTGGAGGCGGCCCAAATGCAAAACTCGGAGGTGTGCTACCTGTGCCGGGTGTGCAGCAACGAGTTTGAATCGCGCGAGCTTTACGAAGCGCACTCCACGGAAGCCCATCCGGGGATGAAAATGGAACTTGTCGAGTCGGGTGTTGCGTCGGATGATATGGACAAGCCGGATGATCAGACGGAAACTGGTGCACAGGAAGGTGGCGACGGTATTGTAAAGAATCAAGAACAAGTTGTAAAGGCCGAAGAAGGTGGGGATGGCATCAAGACAGAGGGTGGAGAGAAGAAAGAGGGCGACGAGGAGGACGAGGAGCAAAAGAGCAGTGCAGAGAGTGGTGGATTTACCCTAATTTTCAAGTGTAAACTGTGCTCTGGTCGGTTCTTGAAGAAAAAGTCGCTCGATTGGCATCTGCAAACACATCGCTCGATTGCGAAACAAGGGGACGGAGTCGCCATTCTTCCCGATATTGGTCCGGACGCGATTGCTGATCAGCCGAAGATGAACAAGTGCACGGTTTGTGGCCAGATATTCGACAATGAGATTCTTTTCCACGAGCACATGCGTTCACACCAGCGAGGTTCCCGTATAGTATCCATGGGGGGATACATGACGCAAACGCCGCCGACTAGACGCCGGCGCACGGGTGGCCGTAGCCTCATACAGTGCGATTTGTGCAAAAAGACGTTCATGTACCGTAGCCAGCTGCATCAGCACACCATGCTGCACCATCAGCCGGGCAAGCCGTATGAGTGCAAAATCTGTCACTATAGCTTCGTACACAAGCTGAACCTGAAGCGTCACGAGCTGACCCACTTGCGAGAACCACCACGACCGCAGGACAATGCGATGGGTACTTCGTCCATGCTCGATCAGCAGGATAACGATCAAGATGATCAGCTCGACAACTCGCATCTTTTGCAGCCGCTTGTGCTATTGGATGGGCCAGAGGATGAAACGAACGGTGCTACCGGTGGTCGGGATGGTAGTAGTGGCACCACCGGTCAAAACGATGGTGATGGTGCGGACCAGTCGGGATCGGCAATGGATGGTCGAACATCGGTAAACGTTGCTGACGATGGTACGGGTGGCAGTGGACGCGGATGGACACAGAAAAAGTTCAAGTGCGTCGTTTGCTCGCTAGTGTTTACCAGACAGAACGAGCTGGTCGTGCATCTGCAGACGCACATCGAGCGAATCAACGAGGCAAAGAACCGCACAGCGGCTGTCGCCGCTTCAACGCTCGCAGAGACAGGCATTGCGCCCACTGATCGGCAGTGCAAGCTGTGCCACAAGGTGTTCAAGTTTAGCTGCCAGCTCAAGCAACACCATCTGCTGCACCATGCGCGTGAAAAGCCGTTTGAGTGTCGCACCTGTCACTATCGATTCGAGTTCAAGGGTCACCTGGTGCGGCACCGCGCCAACCATCATCCAAACGAGGTTAAAGACGAACCAGGTGCGGATGGGTCCAGTCCGTTCCTTACTTCCACCCCGATTCGCGGGACTGCCGGTCGCGGAGTCGGTGGTGCAACAGCGTACGGTGAGGGCAGCAGCCAAGCGAGTGTGCCAAAGTATGGTGGTTTAGTAACGGACGATGTCATTATCGCTCCGACAACGTCATCCCCACGTTCGGAAAGTGGGTCGGCCGGTGTGCCGACGCACCAGTGCCCGATGTGCTCGCTAAAGTTTATCAAAGCGCGCTCGCTGGCCATGCACATGCGGATACATCTTGGTGGACGGAAGTTGCGCCGTGTCATTCCGGCGTCTGCGACAGAACCATCACCACCGACGGATGCACAAACCGTCGTTGGCACTGGTGCCGATAAGCTCGTCTGCCGGTTCTGCTCCGGCACCTTCCCGACGGCACACGAGCTAAAGACCCACATGATGACGCATATTGGTAGTGAAGCGATGGATCTGGAGGCGCCGTTTGGCATAAGTGCGTTCAACATGCTACACGAGAACATGTTTAACGATTCGATGGGCGGTGAAGGTGGCTCTTCCGGTGGTCCGCTCGGTGCGGAAGATCACAGCAGTATGGGCGGTGAGGGAGGTAGCAACAGCCGGGCGGAAGGGGGTAGTACGGATGGTGACTACCAGCATGATGACGGTGAAGATGGTAGCGGGGGCGATCCGCTGTTCGATAGCTCCAATCTGGAGCTCGTGCTGGAGGATAATATTCTCGATAAAGATTTTAACATGCGATATCAGCCACAAAAGCGTAGATCCTCCAAAACAGGCCAGAacaatggggacggtggtgatgacgatgatggggaagaggaggacgatgatgatggagataacgatgacgacattacggacacgaacgatggtgacggtggtgccggtgaggacgacgacgaggaggacgaGGGTGAGCAGTCGTCCGCTTCGACGATGGCCAGCTTCCAGCGACACATGAACCTGATGGCAACGCATCGCTCGCGTTTGGCCGCGACGGCAGCATTGTCAGCCCGCCTTCAAGCAACGCCGTCTGCATCTTCCTCGCAGTCATCGTCCTCGGCCAAGGGCAAGATTGTGTGCGAGCTGTGCAAGAAGGAGTTCCTGTATCCGTGTAATCTCAACCAGCACAAGCAGCTGCACCATTCAAAGGAGAAACCGCACGAGTGCCGCGTCTGTCACTATCGCTTCGAGTATGTTGGGCACCTGCAGCGACACATACGGCAGCAGCACGAAAAGATGGCAGAGGAACTTTTAACGCCGGCGGAACCACAAACGTTCGGTTGTAACTTTTGCGGCGAATCGTTTGATTCCAAGCCTCTATTAACTGCACACGTTCACGCAATGCACAGAGGCGAGAAACCGTTCCAGTGTGACAAATGTCCGGCAACGTTTAGTTATAAGAAATCGTACGAAACTCACCGAGAGGAACATTACTTGAAAGCAAGTAATGGAGCCTTCAAGTGCAGTTTCTGCaaaaaaaCTTTCAACAGCGCACAAAAAGTAGACAACCATGTTTGCATTCAATAG
- Protein Sequence
- MEWGDSLATDRVIAGGGASVTSGSPMTPGIGHHLQGAADVGVVGPNAFVTHGGYGNETGTQSHQRRMIAAAGVNQYAGGRGVDGSAGTSAAGYFHDQLGQSVVVGTTMGHFVGVEATGAGAYATAGVVTGGMVPGGGGRTVGPMVASPNAASPTGVPGMGGGNTYGHSTPTHVASYLQQQGSPSGMQRMNDMSALQTPVVVAQQQQQQQQMVPEHRRAQLPMHSDFSSGASRSPFPAAVSLPSSSPCLVDATVAGGQMAACSKPAEMVMNNDPLKAGNQMPVIGQQQQQTRASQIEATEETENLEDVLDSKLLPEASGIKANNILTQSGGANDGQLTPAMVLPHSTEQPRKRSVKHVRFVEPNEENSFDGMRQSRGNVVSPHPLGLGHRNDEEGDEDEEEEEEEDDDMDELSLMQNLPPVESLLVEMDEPLDDEDNDDEEVEMEDDDDNGGRRRMPGRRRRGGHHLSMHRTPRSKHSESIELELEPLLPEIEMGEGTAGDEKGDDNRIAPVAHVCRVCLCDEKPDGEDGETRPMESLYCTVVPEYQSRSLYSILVAVCHPLHLGSNAGMPDRICGPCKTKLLAAYELYDMCLRNDEMLRRKYQEKLLLASSAAGGGGEMRRIKKEKLDNNGVDAIGDDDEDDYYRGGTGKRGPMRMNDQDDTYLYDRQYPLHAASTAGRNSTFAALPSRFQQPQQQAHGRWGKYQRHQSHLSNQMRIQHQVANGPEALRQLHDGRSKQAASGQAARSAASYDYNSFHRVLPNGSHQCTKCMREFKYHSYYKNHYISQHDPSKPFKCRKCHYTFLTERWLIVHMRTHLAAGDVMSMTTSGGASMGTDAGAMDSFDSSMDGSVDRRKGARGFDCYYCDMTFPAHALQKRHMLSAHADKHRGLECPICQCRFANQSSFLLHLQEHKDQKRLRKTIKTEDGGKGEEGAGGGMQVKREYNCTVCTAIFGREVQLNEHMQEQHPDAFLAMHTELAFMCGVCLAEFNDRAALENHTSSTHTEAELAEAAAKGMSQSPEAESGSQNEVKQEEENNGNGTNAEMTTNDASAEETNGTDKPPEGCSLVYKCKLCQSRFVTKSSLSSHLETHVAAMKRAATKRPYSETGDNDGADGADGAIDDDDYSGEEDDDDDEHSAGGEKRSKRSKLQDEDDDTTEEMPIDPDEISFNPDTGEQVFTCQVCGKVINTVSQFRRHKRVHSPKGRPFECHICFYRFAMKYSYTAHMLRHELGCNPTQPTTYRCSKCSETFTRRKLLSQHIAAMHGRWSDPSGGSPMYGVSMGGSSSMSARAAMGQIAAMSTGSGSGRGTHTCPICSESFTRESVLNGHMKTHNLEAAQMQNSEVCYLCRVCSNEFESRELYEAHSTEAHPGMKMELVESGVASDDMDKPDDQTETGAQEGGDGIVKNQEQVVKAEEGGDGIKTEGGEKKEGDEEDEEQKSSAESGGFTLIFKCKLCSGRFLKKKSLDWHLQTHRSIAKQGDGVAILPDIGPDAIADQPKMNKCTVCGQIFDNEILFHEHMRSHQRGSRIVSMGGYMTQTPPTRRRRTGGRSLIQCDLCKKTFMYRSQLHQHTMLHHQPGKPYECKICHYSFVHKLNLKRHELTHLREPPRPQDNAMGTSSMLDQQDNDQDDQLDNSHLLQPLVLLDGPEDETNGATGGRDGSSGTTGQNDGDGADQSGSAMDGRTSVNVADDGTGGSGRGWTQKKFKCVVCSLVFTRQNELVVHLQTHIERINEAKNRTAAVAASTLAETGIAPTDRQCKLCHKVFKFSCQLKQHHLLHHAREKPFECRTCHYRFEFKGHLVRHRANHHPNEVKDEPGADGSSPFLTSTPIRGTAGRGVGGATAYGEGSSQASVPKYGGLVTDDVIIAPTTSSPRSESGSAGVPTHQCPMCSLKFIKARSLAMHMRIHLGGRKLRRVIPASATEPSPPTDAQTVVGTGADKLVCRFCSGTFPTAHELKTHMMTHIGSEAMDLEAPFGISAFNMLHENMFNDSMGGEGGSSGGPLGAEDHSSMGGEGGSNSRAEGGSTDGDYQHDDGEDGSGGDPLFDSSNLELVLEDNILDKDFNMRYQPQKRRSSKTGQNNGDGGDDDDGEEEDDDDGDNDDDITDTNDGDGGAGEDDDEEDEGEQSSASTMASFQRHMNLMATHRSRLAATAALSARLQATPSASSSQSSSSAKGKIVCELCKKEFLYPCNLNQHKQLHHSKEKPHECRVCHYRFEYVGHLQRHIRQQHEKMAEELLTPAEPQTFGCNFCGESFDSKPLLTAHVHAMHRGEKPFQCDKCPATFSYKKSYETHREEHYLKASNGAFKCSFCKKTFNSAQKVDNHVCIQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -