Aepi001809.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles epiroticus
Gene Symbol
grau
Assembly
GCA_000349105.1
Location
KB669726:159593-165072[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.43 26 4.9 0.0 2 23 161 183 160 183 0.96
2 30 0.52 32 4.7 0.1 6 23 192 209 192 209 0.96
3 30 0.00044 0.027 14.3 0.6 2 23 214 236 213 236 0.94
4 30 0.00055 0.034 14.0 1.8 1 23 244 266 244 266 0.93
5 30 0.0032 0.2 11.6 1.0 2 23 270 292 269 292 0.92
6 30 1.7e-05 0.001 18.8 0.2 1 23 298 320 298 320 0.97
7 30 0.002 0.12 12.3 0.9 2 23 330 352 329 352 0.95
8 30 0.071 4.3 7.4 0.5 1 23 359 382 359 382 0.96
9 30 4.9e-07 3e-05 23.6 0.6 1 23 387 409 387 409 0.97
10 30 0.0069 0.42 10.6 3.0 1 23 415 439 415 439 0.97
11 30 0.42 26 5.0 0.2 1 23 683 706 683 706 0.96
12 30 0.34 21 5.2 0.1 6 23 715 732 715 732 0.96
13 30 3.3e-05 0.002 17.9 0.8 2 23 737 759 736 759 0.96
14 30 0.0087 0.53 10.3 7.3 1 23 767 789 767 789 0.97
15 30 0.0002 0.012 15.4 0.4 2 23 793 815 793 815 0.93
16 30 1.8e-05 0.0011 18.7 0.2 3 23 823 843 821 843 0.96
17 30 0.017 1.1 9.3 4.2 2 23 853 875 852 875 0.95
18 30 0.19 12 6.1 0.5 1 23 882 905 882 905 0.97
19 30 4.1e-06 0.00025 20.7 0.8 1 23 910 932 910 932 0.98
20 30 0.03 1.8 8.6 2.4 1 23 938 961 938 961 0.97
21 30 8.4 5.2e+02 0.9 0.0 2 23 1170 1192 1169 1192 0.90
22 30 4.2 2.6e+02 1.8 0.6 6 23 1201 1218 1201 1218 0.96
23 30 4.7e-05 0.0029 17.4 0.6 2 23 1223 1245 1222 1245 0.96
24 30 0.0005 0.03 14.2 0.7 1 23 1253 1275 1253 1275 0.99
25 30 0.00029 0.018 14.9 0.2 2 23 1279 1301 1279 1301 0.95
26 30 3.6e-05 0.0022 17.8 0.4 3 23 1309 1329 1307 1329 0.96
27 30 0.001 0.064 13.2 1.4 2 23 1339 1361 1338 1361 0.95
28 30 0.011 0.68 9.9 0.9 1 23 1368 1391 1368 1391 0.97
29 30 1.1e-06 6.9e-05 22.5 0.8 1 23 1396 1418 1396 1418 0.98
30 30 0.27 17 5.6 6.2 1 23 1424 1447 1424 1447 0.95

Sequence Information

Coding Sequence
ATGAATGAAATATGTCGTCTTTGCCTTGAAAGTCTACCATTCGAGACAGCGATATCGATACGGGACCAAGATTTTCAGGAGAAGTTAAAGGGTGTGTTTCATTTTGAAATTGCACACGACGCGCTGCTTCCGGAACATGTTTGTCACGACTGCAGAAGTACCGTGCTGTACTGCCACTCTTACTTCCTCCAGGTTCGAACCAATCAAGATCAGCTGGTACAGGAAGCAAAGGAACTCATCCTGCAGCCCGAAGAAAATGACAACCTGGAATCACTGTTCGATGCGAATTGTTTCGAGATGGAAGAGCACAAATTGGAAGATGGGTCGGATATTATGCAAGAGGACGCGTTTGGCCCTTTAGAGGGATTGGAACAGGTCGATCTTCCTGAACGGACGGCAGAGCAGGACACATGTGCAAAAGAAGAATCGAAATCTAGATGGCTGGAAAACGATCAGATCATAAAAGATTTCATTAGACTGGAGTGCGAGATATGTGCGGCAACGTCTGAAAGCTTCGCGCTGCTGCTAGACCACTACCGAACGGTGCATGAAACGAAGGGATATGTGCGGTGCTGCGAAAAGCAATTTTTTCGACGCTACATGCTTGTGGATCACATTGCGGCCCATCGCGGTACGATACGGTGTGACATTTGCCAGAAGGCGTACAAAACGAAGCGGTATCTAGCGTTGCACACTGCCAAAAGCCACAGCCGGGTGGAAGATCGACCGTTTAAGTGCAGCAAGTGTCACGTGTCCTTCCCGAAGCAGTACTTGCTACGGGCGCACGAAGTCCTGCACATCCAGCAACGGTGCCAGATCTGCCATAAGGTGCTCTCCAGCATCCAGTCACTGAAGGTGCACATGGTGCAGATGCACAGTGACGACGGGAAGTACATTTGCGATACTTGCGGGAAAGTGTTCCGTACGAAACCGGCGATGGATCGGCACATTAACGAACATTTGGGGCTGGATGTGGTGCAACGCGTGCAGTGTGAGTACTGCCAGAAATGGTTCAACGGGAAGTACAACCTAAGCAAGCACGTTCGCTTCCTGCACAAGGAGGGCGGCCAGCTGTTTCCGTGCGATTCCTGCCAACACGTGAGTCCCAACAGTCGGGCGCTGGCGAATCACAAACAACGTGTGCACGTGGAGGAACGGTTCGAGTGCGAGTACTGTGGCAAGCGGTTCAAACGGCGGCCCAATCTGCGGGAACACGTCGCTTCGCACACGAACGTTCCGCTGTACTCGTGCGAGATTTGCAACAATCGAACGTTTAACTCGAAGGCGAACTACTTTACGCACCGGAAAAGCAAACATCCACACGAGTGGGAGGCACAGAAGCCGGCGCCATCCGAAATGGATGAAAAATGCCGTCTGTGTTCGGCAGGCTGCAATTCCACCGGTACAACACCGATCACGGACGTGGAGTTTGGCGCGAAGCTAGAAATGGTGTTCACATTTCCGGTACTTCCAGAAGAGCCACTTCCAGAACGAGTTTGTCAGGAGTGCGTGGCGATCGTGTCAGATTTTCACACGTACAGCCAACGGGTTAAATCCCATCAGGAGCAGCTGCGGGCCAATTTGAAGGAGCAAAAATTTGAACCCTTCGAGGTAGTGAAAATTGAAGCTCTAGAAGACGACGATTACTATGACATCGAGATGGAGGAACAGATGGAGGTGTTGCAGCAACACGAGGAGATTCGCGTTACCGTAACACGTAAGCCAGCCAAGCAGGTGCTTCCTAGTCACACTGCCGATAGCAAGAGTGTTCCAAATGCACAGGAAGAGgatgatcccgaggaagagggcgaggaggtcgatgatgacgaggacgatgatgacgaggacgatgaagacTTTGTACCGAAAGTTGATCCCAAGGATGGCACCCTCAAGGTACCGGTTCGCCGTCGACGACACATGAAGCAAATGAAGGTGCCACCAAAGAAGCGAACCGTAAAGACAGAAAAACAATCGGAAAAGCTGGAACCGGAGGAACTGGACAAACAAAACGAGGAAGACAAACGGATACAGGAGTTTTATAAATTTGAATGCGAAATTTGCTCCCAGCCGATGGATAGCTTCGTTTACCTGCAGGGCCACTATCGGCGTGAGCACGGCACGAAGGGCTACATACGGTGCTGCGACAAGCTGTTCTACCGGCGCTTCCAGCTGTTGGACCATATCGCGGCGCACCAAGGCACGATCAAGTGCGAGGTGTGCCAGAAGAGCTACAAAAGCAGTCGCTATCTGGCACTGCACATGATGAAGAGCCACAGCCGCGAGGAGGACCGGCCGTTCAAGTGCGACAAGTGCCATCAATCGTTCCACAAGGAGCACCTGCTGAAGGCGCACCAAGCGAACCATCTGTCGGAGAAGTGTCCGATCTGCGAGAAGGTGGTATCATCCAAGTATGCGCTCAAGGCGCACGTCTCGCACATGCACGGTAGCGACAGCAACCAGATCTGTGACGTGTGCGGGAAGGAGTTCCGCACCAAGCAGGCCATGGAGCGGCACATTAACGAGCATATGGGGGTGGAAGTGGTGCAGAAGGTGCAGTGCCATGTGTGTCAGCGCTGGTTCCACGGGAAGTACAATCTGCGCAAGCACATACGCTTCATGCACATTGAAGGCGGGAAGGTGTTTCCATGCGATTTGTGTTCGCACGAAAGTCCGAACAGCCGGGCGCTGCTGGATCACAAGAAGCGAGTACACGTGGTCGAGCGGTTCGAGTGTGAGCTGTGCGGGAAGCGGTTCAAGCGCAAGCTGTATCTGCGGGAACACATTGCGTCACACACGGGGCAACCGCTGTACGAGTGCGGGATCTGTGATGCCAAGTTTAACTCGAACGCAAACTGTTACAACCACCGGAAGAGCAAGCACCCGGAGGAGTGGCAGGCACGAAGGCAAGCATTTTTCGAGGCACAACGTAAGGCGCCGGACACTGCGCTTAAGAAGGAACAGGAGCTGGAGTGTACCATCGGCGTATCGATAACGGACGAATCATTTCAACGCAAGCTACAAACAGTGTTTTCGTTCGAGCTCTCGACGGAACAGGCCCTACCGGAACAGGTATGCCAGCAATGTCAGACGACGGTGGACGAGTTTCACGTGTACAGCCAGCAGGTGGAAGCGAACCAGCAGCAGCTAAAATCAGCACAGCCGGTGGAAGATGTTGCACAGAGCCGCTCGTTCGACAGTGTGAAGGAAGAGCCCGACTTTAAGATTGAAATCATTTCCACGAATGAGACGGCAGAGGAGCTACCGCTGGGTATTGAGTGTGTGGATGTGAAGGAAGAGTACGATGAAGGCATGTTCCCCGAATCCGATCTGGAGATCGGGTCGGAATCGGGGATATCTGCTGCTGAAGCGGAGGCGGAAGCACCTCGACGCAAGGGTCGTCGTAAAGCGAGGGAAAGAAAGGTGAAGAACAAGGAAAAGGAGGATGGAAACAGTCAGGCTAGACTGCAGGAGAAAGACGAACGGATCAAGGAGTTCTATACGCTCGAGTGTGAGATATGTTCCATTCTTTTGGACGACTTTGTGCAGTTGCTGGAACATTATCAGCTGGTGCATGACACCCGTGGGTACATACGGTGCTGTAATAAGCAACTGTTTCATCGCTACACCCTGCTCGACCATATCGCCGTCCATCGGGGTACGATCCGGTGTGAGGTGTGCGACCGGACGTACAAAACGAAGCGCTATCTGGCGCTGCACATGGCTAAAAGCCACGGCACGGACGAGGAGCGCCCGTACAAGTGCAGCAAGTGCGCGCTGTCCTACCCGAAGGAGTATTTGCTTCGTTCGCACATGCTAATGCACGTGCAGGCCGAGTGTAACATCTGCAGCAAGGTGTTGTCGAGCAATTACGCCCTCAAGGTGCACCTGAACCAGGTGCACAGCGACGACGCGAATCAGATCTGTGCGACGTGTGGCAAAATGTTCCGCACCAAGGCGGCCATGTTTCGGCACATCAAGGAGCACATGGGACTGGAACCGATCGAGCGGATGAAGTGCGAGTACTGCCAGAAATGGTTCAACGGGAAGTACAATCTGAACAAGCATGTTCGCTTCCTGCACAACGAACAGGGGCAGGTGTTCCGGTGCGATATCTGTGGGCACGAAAGTCCCAACAGTCGGGCACTGTCGTATCACAAGCAGCGGGTGCACGTGGAGGAACGATTTGAGTGCGAGTACTGTGGCAAACGGTTTAAGCGGAAGCTGTATCTGCGGGAGCACATCGCTGTGCACACGAACGTTCCGCTGTACACGTGTGAGTACTGTGGGATGCAGTTTAATTCGCACGCGAACCACTTTACGCACCGAAAAAACAAGCACCCGGAAGAGTGGGAAGCGCACAAGCGGATGAGGATGCAAAAGAAGATGAGCAAAAACCAGGCGGATGGAAGGCCGTGTGCAATGGATTAG
Protein Sequence
MNEICRLCLESLPFETAISIRDQDFQEKLKGVFHFEIAHDALLPEHVCHDCRSTVLYCHSYFLQVRTNQDQLVQEAKELILQPEENDNLESLFDANCFEMEEHKLEDGSDIMQEDAFGPLEGLEQVDLPERTAEQDTCAKEESKSRWLENDQIIKDFIRLECEICAATSESFALLLDHYRTVHETKGYVRCCEKQFFRRYMLVDHIAAHRGTIRCDICQKAYKTKRYLALHTAKSHSRVEDRPFKCSKCHVSFPKQYLLRAHEVLHIQQRCQICHKVLSSIQSLKVHMVQMHSDDGKYICDTCGKVFRTKPAMDRHINEHLGLDVVQRVQCEYCQKWFNGKYNLSKHVRFLHKEGGQLFPCDSCQHVSPNSRALANHKQRVHVEERFECEYCGKRFKRRPNLREHVASHTNVPLYSCEICNNRTFNSKANYFTHRKSKHPHEWEAQKPAPSEMDEKCRLCSAGCNSTGTTPITDVEFGAKLEMVFTFPVLPEEPLPERVCQECVAIVSDFHTYSQRVKSHQEQLRANLKEQKFEPFEVVKIEALEDDDYYDIEMEEQMEVLQQHEEIRVTVTRKPAKQVLPSHTADSKSVPNAQEEDDPEEEGEEVDDDEDDDDEDDEDFVPKVDPKDGTLKVPVRRRRHMKQMKVPPKKRTVKTEKQSEKLEPEELDKQNEEDKRIQEFYKFECEICSQPMDSFVYLQGHYRREHGTKGYIRCCDKLFYRRFQLLDHIAAHQGTIKCEVCQKSYKSSRYLALHMMKSHSREEDRPFKCDKCHQSFHKEHLLKAHQANHLSEKCPICEKVVSSKYALKAHVSHMHGSDSNQICDVCGKEFRTKQAMERHINEHMGVEVVQKVQCHVCQRWFHGKYNLRKHIRFMHIEGGKVFPCDLCSHESPNSRALLDHKKRVHVVERFECELCGKRFKRKLYLREHIASHTGQPLYECGICDAKFNSNANCYNHRKSKHPEEWQARRQAFFEAQRKAPDTALKKEQELECTIGVSITDESFQRKLQTVFSFELSTEQALPEQVCQQCQTTVDEFHVYSQQVEANQQQLKSAQPVEDVAQSRSFDSVKEEPDFKIEIISTNETAEELPLGIECVDVKEEYDEGMFPESDLEIGSESGISAAEAEAEAPRRKGRRKARERKVKNKEKEDGNSQARLQEKDERIKEFYTLECEICSILLDDFVQLLEHYQLVHDTRGYIRCCNKQLFHRYTLLDHIAVHRGTIRCEVCDRTYKTKRYLALHMAKSHGTDEERPYKCSKCALSYPKEYLLRSHMLMHVQAECNICSKVLSSNYALKVHLNQVHSDDANQICATCGKMFRTKAAMFRHIKEHMGLEPIERMKCEYCQKWFNGKYNLNKHVRFLHNEQGQVFRCDICGHESPNSRALSYHKQRVHVEERFECEYCGKRFKRKLYLREHIAVHTNVPLYTCEYCGMQFNSHANHFTHRKNKHPEEWEAHKRMRMQKKMSKNQADGRPCAMD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-