Aepi000455.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles epiroticus
Gene Symbol
-
Assembly
GCA_000349105.1
Location
KB671916:28255-42817[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 34 0.3 19 5.4 0.5 1 23 296 320 296 320 0.96
2 34 0.053 3.2 7.8 2.8 2 20 326 344 326 347 0.94
3 34 0.0022 0.13 12.2 2.2 1 23 353 375 353 375 0.97
4 34 3.6e-06 0.00022 20.9 1.9 1 23 381 403 381 403 0.94
5 34 0.00029 0.018 14.9 1.5 3 23 411 431 409 431 0.97
6 34 0.0012 0.074 13.0 2.6 1 23 437 459 437 459 0.98
7 34 0.19 12 6.1 0.1 1 23 658 683 658 683 0.94
8 34 0.039 2.4 8.2 3.5 3 20 690 707 689 710 0.94
9 34 0.00067 0.041 13.8 0.7 1 23 716 738 716 738 0.97
10 34 1.2e-06 7.3e-05 22.4 2.2 1 23 744 766 744 766 0.93
11 34 0.0014 0.083 12.8 5.9 2 23 773 794 772 794 0.97
12 34 0.0033 0.2 11.6 2.0 1 23 800 822 800 822 0.98
13 34 0.05 3 7.9 5.5 1 20 1144 1163 1144 1166 0.94
14 34 0.00035 0.021 14.7 2.4 1 23 1172 1194 1172 1194 0.96
15 34 7e-05 0.0043 16.9 2.1 1 23 1200 1222 1200 1222 0.94
16 34 0.00035 0.022 14.6 1.2 3 23 1230 1250 1228 1250 0.96
17 34 0.0089 0.55 10.2 3.0 1 23 1256 1278 1256 1278 0.97
18 34 3.4e-05 0.0021 17.8 1.0 3 23 1286 1306 1284 1306 0.98
19 34 3.1e-06 0.00019 21.1 2.0 1 23 1312 1334 1312 1334 0.99
20 34 0.0021 0.13 12.2 0.9 1 23 1340 1362 1340 1362 0.98
21 34 0.052 3.2 7.8 4.3 1 20 1646 1665 1646 1668 0.94
22 34 3.4e-05 0.0021 17.9 2.5 1 23 1674 1696 1674 1696 0.97
23 34 4.6e-06 0.00028 20.6 2.6 1 23 1702 1724 1702 1724 0.95
24 34 0.00069 0.042 13.7 1.9 2 23 1731 1752 1730 1752 0.97
25 34 0.00095 0.058 13.3 2.3 1 23 1758 1780 1758 1780 0.98
26 34 1.5 89 3.3 0.2 1 23 2035 2059 2035 2059 0.93
27 34 0.4 24 5.0 5.5 1 20 2064 2083 2064 2086 0.94
28 34 0.00052 0.032 14.1 1.6 1 23 2092 2114 2092 2114 0.97
29 34 9.6e-06 0.00059 19.6 1.4 1 23 2120 2142 2120 2142 0.93
30 34 0.00013 0.0077 16.1 0.3 3 23 2150 2170 2148 2170 0.97
31 34 0.00062 0.038 13.9 2.0 1 23 2176 2198 2176 2198 0.97
32 34 7.7e-06 0.00047 19.9 1.8 1 23 2204 2226 2204 2226 0.98
33 34 9.4e-06 0.00058 19.6 1.2 1 23 2232 2254 2232 2254 0.99
34 34 0.0061 0.37 10.8 0.1 1 23 2258 2280 2258 2280 0.97

Sequence Information

Coding Sequence
ATGGACGTGAAGGAAGAGCGCATTCCTTCGGTGGGAATCGAGGTGCAGTGCTGTCGCGTGTGTGTAATCGAGTCGGAGGCAAAACACTGCATGGACGAGATCATCGTCCCCGAAGGCTCCCTCAGCTTGAACATGATGCTGCAGACAATGTTTCCAACGTTTGATTTTGGTGAAAACTCTAAGCTTATCAagcagcagcagcagcagcagcagcagcaTTTGTTTTTGTCCAAAAAGGTTTGTGAAAACTGCAAGCACAAAGTGCTGGTCGCTTACGAGCTGTACATGCTGCTGGCTGAAAGCGAGGAACGGCTGCAGCAGTACCTGGATGAGGCCGATTTAATCAAATCGGAACAAAGCTGTGCTCCATACGAGGTGCTAATTGAGTGCAGCTATAATGATGACGATACAGCCTTCGCGGTGGAGGAAGAACAACCAGTTGTGGAAATGGTGGAGGTATTATCTGCAGATGAAGAAGCCATCCCAGAGCTCGAGGTGTTGGATGAGGTGACCGGTAAGCGTCGGTCGGGCAGAAAGCAACGGGCGGAACCGACAAAAACAGAAGCAGAGAACAAACGAACGCCTAGTAAGAAAATTAAAAAGGAACGCACGGACTCAGGCAGTGGGGCAGAGGATGGGATGGATGTGATTCCGGAAGGAGGTAACGATCAGCTGGATGAGTCGAATGTGGACGAACAAATCATAAAGCCAGTGGCAAAGAAGAGAGGTCGTAAACCTAAAATCAAGACGGAAAGCACCTCCGAGAGCACAAACTTGCCAGAGGTTAAGAAGGAAAGGAAGAAAAGAGCAAGAACTGAAGCGGCGGACGGGGCAGACGGTTCATCGGATCCGACTGGAGGAGAACTACAGTCCAAGGTAGATGTGTATCAGTGTCAGCTATGTGAAGGACACACATACGGATCGCCGATGGAGCTTACCGTGCATCTGAAGAAGGAACATCCGGACCTAATCCGAACGTGTGACAAGTGTCCGAAGGTATTTATGACTGAAGCTGCGTACCAGCATCACCAGTATTGTCACGCAACCCTGCGCTCCTACTTCTGCATGTTCTGCGACAAAGGCTTTCAGACCGAGAATCTCCTCAAAAGTCACACGCGGTCTCATACGCATCTGGTCGAGTTTTTATGCTCGCTGTGTGGTAAAAAGTTTAACAACAAAAGTAACCTACGCCAGCATCTGGTGCGACATTCGGGCGTTAAACCGTGGGCCTGTACGCAATGCCCTAGTCGCTTCTGTACCAAAGGAGCATTGAATTTGCACCAGAGAACACATTCAAAGTTAAAACCATTCAGCTGCGACACGTGTGGCTCTCAGTTCCACACGCGATACTCACTGATCAAGCATCAGCTAATCCATACGGAGTGTCGCATGCACGAACCACTGCACGAAAATGGTTCCCAAAGTTTGCAAATTGTACTGGAGAAACTGTTTCCGGGCGTGTTCAACGAGGAGCAGGTACAGCACGACTACACCATGAACTGGCCGATGGTTGTCTGCCAGGAATGTAAGCGAAAGGAGAACGAGGAGGAATGTGCGATCGATGTACAGGCGCAGGAGTTTTTGGAATGTGATCTCATTCCCGAAACCGAGCCAGAGCCAGAAACCAAACCGCTGACCGTAACACTCCAACGGTCAACGAATTCGCACAAAAGCGAGCCCCCGGCAAAGGTGACGCGGACGAAGAAAGGTTTCACCGCAACGGAGGTTACGGACATCAAGAATGAGTTAGCGCAGCTGGATGAGCAGAACGCATTAACTCTCCAAGAGGATGATGAGATAGAATTTGATACAGTAAAAATCATGGACGAGCCAGAATGGAAGCCCCCGAAGGGTAGGGGACGAAAACCAAGAACTCCCAAAGTGAAAGTggaaaaggttccacaggaaaggaaaaagcgagaacgaaaggcgaaaccgaaggaacaggaaacggaatccaaaacggaGCTGTATAAATGTCAGCTGTGTAGCGCTGGACCAACGTACGATACTCCCGGCGAGCTAACGGAACATCTTAAGACGGAACACATGCATCAGATACGGCCCTGTGACAAGTGTCCGAAGGTGTTTGTCAGCGAGCAGACGTTCCAACATCACCAGTACTGCCATGCAACGGGACGCTCGTTCTTCTGCGACTTTTGTGACAAAGGCTTTCAAACGGAGCCCTTGCTGACAAGCCACGTAAAGACGCACACCCGTGGTCCGAAGTTCCTGTGTTCGTACTGCGGAAAGGGCTTCACTAGCAAGAGCAGTCTGCAGAAGCATATGACATTCCACACCGACAGCAAATCGTGGCCCTGCAAATTGTGCCCATGTCGATTCAACACGAAAGCTTGTCTGCACGTTCATATGCGCACCCATACCAAAACGAAGATTTATACCTGCCCTACCTGTGGATCGCAGTTTAACAAGCACTACTCGATGGTAAAGCATCAGATAATCCACACAGACGATAAGGACATTCGATTTACCAGCACGGAAATATTGAAGCTGAGATACCAAAAAGAGATGGGACAGTGTAGCCAAAACATGGACGAGGAGCAAAGTGAAGAGCTGGTAAGCTGCTGCCGTATCTGCATTTCAACCAGGAATGTGGAGTATTGCATACACGAACGTGTCAATCAGGAGGCATCTCTAAGTTTGCAATACATGCTGGAGAAACTGTTTCCGTCCGCGTTCAATGCGGTCCAGGTAAGGCACGATGGCAAAATGCGCTGGCCGTCCAAAATATGTCAAGAGTGTAAGCGGAAGGTGTTGGTAGCGTACGATTTGTACGCGCAATGTCTAGTAAGTGCCGATCGCTTGGAAAGAATGTTAAGCGCGCTGAAGGATGGAACTACAATCCGGGAAGATATAAATGTTAACATGATTGAGGAGGAAACAGCTAAAATGAACGATGTTCCCAAAGAAAACCCCCTCGATGGTTATCGTGTTCCGGTTACAGCACACCAAGAACAGGAGGAATCGAATGATAAAAGTCATACAGAAGGCCATACTTCTAAGAGACCGAGAAGCCAACGAAAACGAACGGTGGCCGATACAGCCCTATGTACAGAGAGTCAAAATGTTGCTTCAGAGATAACACGAGGTAAATGGAGACAGACCAAGACAGATCACACTTCCAACAGTGGAACCGTTGAAAGCAGCGAGGAATACTTAAGTTCTGGTGGCCTTAAGCTTAACGAGAAACATGAAAATGGAAACCACACTCTGGAAATTATAAATATTCGAGATGACGATATTGGTGTCCAGCTACAGAACGAATCGGCGCAACAAGAAACACTAACGGGTGTGGATAAGCTTGAACAGAGGAACGATCTGTACAGTTGTTTGCTTTGTGATGCACCGACGTACTCCTCGCCGGACGAACGTACCGAACATTTGAAGGAAACCCATCCGGATCAGATTCATAGCTGTAAGCTATGCCCGAAAGTGTTCATGACCAAAGCGGCATTCGAGCATCATCAATACTGTCACGCGACGGGACGGTCACACTTTTGTTCATTTTGTGACAAGGGATTTCAGACGGAAGCGCTGCTAAAGAACCACGTGCGAACTCATACGGATCCGTCGGATTATCTTTGCTCGCTGTGTGGTAAGGAGTTTAACCATAAGAACAAGCTGCGGCAGCACATGATTGGTCATACGGGTCAAAAACCGTGGGCTTGCATGCTGTGCCCATGTCGATTCAGCACGAAAGGAGGATTAACAAATCATCAGAATACGCACACGAAATTTAAAGCATTCAGTTGCGACACTTGTGGATCTCAGTTCAATAAGCATTACTCTCTAATTAAACACAAACTTATCCACACAGGTGAGCGTCCGTTTGGGTGTGAAATATGCAAAATGAGGTTTGTTAACAACTACCTGGTGAAGCGACACATGCGTACGCACACGGGGGAAAAACCGTTCAAGTGTACGTATTGCGAACGCAGCTTCGCCCAAAGCAACGACATGGTGAAGCACATGAAAACGCACGTCGGTAGCAATCCGTACCAATGCGATCGTTGCGAAGCCTCCTTCCGGCTACTGACGGATCTGCGTAACCATTACAAGGAGCATTATCAGGCGGGCGAGCATGGAGCCGGTTCGTCAGCGGAAGAGGATAAAGGGATGCGGTTCACCAGTCTGGATTCTTCACTCGTTGAAACGTCAAAGAGCAAGCGCAAACAAAACCCGTCCGTGTGTTGTTTATTTTGTCTCGAATTCTGCCACCAAACAACATCGGCCAACGCAATGGAGGAAGAGTATCTGCTTTCGAATTTAAAACACGCAATTTGTCGCATTTGTAGCATCCAATCCACCGACCAGTACTGCATGTACGAGATCATCTTCAAGGACGGCACGCTAAGCATGCACATGATGCTGGAAAAGTTAGTCCCATCGGTGTTCAACGCGGAGCAAATGAAGGTGGACGAGTACATGGGTTGGCCTAGGAAAATTTGTGAAGACTGCAGAGTCAAAGTGCTGGAAGCGTATGGTTTGTACGAGCAGTGCATGATGAGTGGCGATCTAGGAAAAAGAATGACGACGAAACAAAGGGTTACGCATGTGACAGAACCGCGTACACCTACACCGACCGATGACATTCAGTATCTAGCGGATGAAAGTGATGAACAAACGGTTAACACTAGGAAATCAGCAAGCAAAAAAGTAACTCGAAAAACAACCACTCGAAGAAGTACAAGCAGCAAGAGCAAATCGACTAGCGGTGGAAGTGGAAAGGTGCAGCGAAGTACAAGAACGTCCGCAAGAAAGGCAACGGAGAAGATCAAGGAAGAGAGCACGAACGAAACAGATGAACCACAGACAAAGATCGATCTTTACCGGTGCCTTCTTTGCGATGCACCAACGTACACCTCACCAAAGGAGCACACTGAACACCTGAAGCAGGAGCATCCGGATCAGATTCATAGCTGTGAGCTGTGCCCGAAAGTGTTCATGACCAAAGCGGCCTACGAGCATCACCAGTACTGTCATGCGACGGGACGCTCGTTCTTTTGCACGTTCTGTGATAAGGGCTTTCAAACGGAGCAGCTGCTTAAGAACCACATGCGAACGCACACGCACGGGACCGGCTTTCTGTGTTCGCACTGTGGACAGGAGTTTAGCAACCGTAGCAATCTGCGTCAGCATCTGATACGTCATACTGGAGAAAAACCGTGGCAATGTGAACTATGTCCGAGTCGTTTCAGTATGAAAAGTTATCTCGACAGGCATATGCACACCCATACGAAAGCCAAATTCTTCAGCTGTGACTCATGTGGATCTCAATTCAGCCGACACTATTCACTGGTGAAGCATCAGCTTATCCACACAGCCATTCCTACACACGCGACGCAAAGTCCAGCGGCTTGCACTTCCAATTGTCCCACGATGGAAAAAGAAAAGCCTGAAGAGGAGCTGATGACAATACAGTTAACGTTCTGTCGTATCTGTGCGGTCCTGAGCACCGAGGACCATTCCATCTACGAAGCCGTGTACAAAAACGGCACCCAAAGCATACACGCAATGATGGAAAAGTTGGTTCCCTCGGTGTTCAATGCGGAACAGGTAAAGGTGGACGAGTTCATGTCCTTTCCCACCAAAGTATGTGGCGGATGTGAAGCAAAAGTGCTGGCAGCTTACGCACTGTACGAGCAGTGCGTAAAGAGTGGCGATCTGTTGCGCAAATGTTTAGCACGAAAGAAACATGCAACGTTTGTTGTGAACATTACCGGTGGCGAGATGGATGCTTCGGAAGCTCTTTCGTCTGTCCCGTTACATGTAGAGGAAGCTCATGTCGGTATGTTAACGAGCCACAAATCCCAGACAACCGTTGTAGAGATAGTGACGGAAGAAGCCTCTTCCGAGGATGCACATTGTAAGGAAGAAATGGCAAACGAAGAAGTGATGGAATTAGTTCCAGTGCTGGATGACGATCAAGAAGTTGGATTGGAGAACGAAGATCAGGATACCGAGAGATTGCCGGAGGAATTTGAAACGGTTAAAGCGAAATTGAAACGAGAAAGAGTTTCAATCAAGCAACAAGACGATCATTTGGAGAAGCCGGAGGAAGGCGAAGTAGTTGTAACAAAATTTCGCTGCTTGCTCTGTACCGATACTACTTATTCGGCACCGGTCGACCTTACGGAGCACCTCAAAAAGATACATCCGGAACAGATTTACACTTGCAGCCAGTGTTCGAAAGTGTTCATGACTAAAGGGGTCTTCGAGCATCACCGGTATTGTCATGCGACGGGCCGTTCGTTCTTTTGCACGTTTTGCGATAAAGGCTTTCAAACGGAGCAGCTGCTCAGCAACCATGTGCGAACCCATACCCACGGGACGGGCTTTCTGTGCTCGCAGTGTGGCAAAGAGTTTAGCGACAGAAGTAACCTCCGGCAGCACGAATATCGTCATACTGGTAACAAACCGTGGGCATGCACCATGTGTCCGAGCCGGTTTAGTACGAAAGGGTATTTGACGGTGCATCTTAATACACACACGAAGGCGAAATTACATAGTTGCGACACGTGTGGCTCTCAGTTCAACAGACGCTACTCGCTAGTGAAGCACCAAATTATTCACACAGGAGAGCGCCACTACGCATGTGAAGTTTGCAACACGAAATTCACGTCTGCGTATCATGTGAAAATACACATGCGAACTCACACCGGTGAAAAGCCCTACAAATGTGGATACTGTGGTCGGGGTTTTGCACAGAAGAACGATATGTTGAAGCATACTAAAACGCACGGGAAACCATATCCTTGCGGTAGGTGCGATGCCTCTTTCCAGCAGATCGAGGACTTGCGAGTACACGTGAAGGAACATGATCGTGCAATGAAGCGCGAGGAGGCCGGTGGTTCTTCGGCGGAACAGTAA
Protein Sequence
MDVKEERIPSVGIEVQCCRVCVIESEAKHCMDEIIVPEGSLSLNMMLQTMFPTFDFGENSKLIKQQQQQQQQHLFLSKKVCENCKHKVLVAYELYMLLAESEERLQQYLDEADLIKSEQSCAPYEVLIECSYNDDDTAFAVEEEQPVVEMVEVLSADEEAIPELEVLDEVTGKRRSGRKQRAEPTKTEAENKRTPSKKIKKERTDSGSGAEDGMDVIPEGGNDQLDESNVDEQIIKPVAKKRGRKPKIKTESTSESTNLPEVKKERKKRARTEAADGADGSSDPTGGELQSKVDVYQCQLCEGHTYGSPMELTVHLKKEHPDLIRTCDKCPKVFMTEAAYQHHQYCHATLRSYFCMFCDKGFQTENLLKSHTRSHTHLVEFLCSLCGKKFNNKSNLRQHLVRHSGVKPWACTQCPSRFCTKGALNLHQRTHSKLKPFSCDTCGSQFHTRYSLIKHQLIHTECRMHEPLHENGSQSLQIVLEKLFPGVFNEEQVQHDYTMNWPMVVCQECKRKENEEECAIDVQAQEFLECDLIPETEPEPETKPLTVTLQRSTNSHKSEPPAKVTRTKKGFTATEVTDIKNELAQLDEQNALTLQEDDEIEFDTVKIMDEPEWKPPKGRGRKPRTPKVKVEKVPQERKKRERKAKPKEQETESKTELYKCQLCSAGPTYDTPGELTEHLKTEHMHQIRPCDKCPKVFVSEQTFQHHQYCHATGRSFFCDFCDKGFQTEPLLTSHVKTHTRGPKFLCSYCGKGFTSKSSLQKHMTFHTDSKSWPCKLCPCRFNTKACLHVHMRTHTKTKIYTCPTCGSQFNKHYSMVKHQIIHTDDKDIRFTSTEILKLRYQKEMGQCSQNMDEEQSEELVSCCRICISTRNVEYCIHERVNQEASLSLQYMLEKLFPSAFNAVQVRHDGKMRWPSKICQECKRKVLVAYDLYAQCLVSADRLERMLSALKDGTTIREDINVNMIEEETAKMNDVPKENPLDGYRVPVTAHQEQEESNDKSHTEGHTSKRPRSQRKRTVADTALCTESQNVASEITRGKWRQTKTDHTSNSGTVESSEEYLSSGGLKLNEKHENGNHTLEIINIRDDDIGVQLQNESAQQETLTGVDKLEQRNDLYSCLLCDAPTYSSPDERTEHLKETHPDQIHSCKLCPKVFMTKAAFEHHQYCHATGRSHFCSFCDKGFQTEALLKNHVRTHTDPSDYLCSLCGKEFNHKNKLRQHMIGHTGQKPWACMLCPCRFSTKGGLTNHQNTHTKFKAFSCDTCGSQFNKHYSLIKHKLIHTGERPFGCEICKMRFVNNYLVKRHMRTHTGEKPFKCTYCERSFAQSNDMVKHMKTHVGSNPYQCDRCEASFRLLTDLRNHYKEHYQAGEHGAGSSAEEDKGMRFTSLDSSLVETSKSKRKQNPSVCCLFCLEFCHQTTSANAMEEEYLLSNLKHAICRICSIQSTDQYCMYEIIFKDGTLSMHMMLEKLVPSVFNAEQMKVDEYMGWPRKICEDCRVKVLEAYGLYEQCMMSGDLGKRMTTKQRVTHVTEPRTPTPTDDIQYLADESDEQTVNTRKSASKKVTRKTTTRRSTSSKSKSTSGGSGKVQRSTRTSARKATEKIKEESTNETDEPQTKIDLYRCLLCDAPTYTSPKEHTEHLKQEHPDQIHSCELCPKVFMTKAAYEHHQYCHATGRSFFCTFCDKGFQTEQLLKNHMRTHTHGTGFLCSHCGQEFSNRSNLRQHLIRHTGEKPWQCELCPSRFSMKSYLDRHMHTHTKAKFFSCDSCGSQFSRHYSLVKHQLIHTAIPTHATQSPAACTSNCPTMEKEKPEEELMTIQLTFCRICAVLSTEDHSIYEAVYKNGTQSIHAMMEKLVPSVFNAEQVKVDEFMSFPTKVCGGCEAKVLAAYALYEQCVKSGDLLRKCLARKKHATFVVNITGGEMDASEALSSVPLHVEEAHVGMLTSHKSQTTVVEIVTEEASSEDAHCKEEMANEEVMELVPVLDDDQEVGLENEDQDTERLPEEFETVKAKLKRERVSIKQQDDHLEKPEEGEVVVTKFRCLLCTDTTYSAPVDLTEHLKKIHPEQIYTCSQCSKVFMTKGVFEHHRYCHATGRSFFCTFCDKGFQTEQLLSNHVRTHTHGTGFLCSQCGKEFSDRSNLRQHEYRHTGNKPWACTMCPSRFSTKGYLTVHLNTHTKAKLHSCDTCGSQFNRRYSLVKHQIIHTGERHYACEVCNTKFTSAYHVKIHMRTHTGEKPYKCGYCGRGFAQKNDMLKHTKTHGKPYPCGRCDASFQQIEDLRVHVKEHDRAMKREEAGGSSAEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-