Adir008788.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- -
- Assembly
- GCA_000349145.1
- Location
- KB672857.1:3035656-3038780[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 8.6 4.8e+02 1.0 0.3 2 11 46 55 45 59 0.77 2 11 0.073 4.1 7.5 8.3 1 23 191 215 191 215 0.96 3 11 0.0014 0.079 12.9 0.1 1 19 229 247 229 249 0.95 4 11 0.28 16 5.7 1.5 2 23 279 300 278 301 0.92 5 11 5.3 3e+02 1.7 1.1 2 15 315 328 314 334 0.76 6 11 5.3e-05 0.0029 17.4 0.1 1 23 342 364 342 364 0.97 7 11 3.3e-05 0.0018 18.1 2.7 1 23 370 392 370 392 0.96 8 11 5.4e-05 0.003 17.4 4.2 2 23 398 419 398 419 0.97 9 11 5.2e-05 0.0029 17.4 7.7 2 23 426 447 425 447 0.96 10 11 0.0021 0.12 12.4 1.0 3 23 455 475 453 475 0.96 11 11 0.088 4.9 7.3 0.9 6 20 485 499 483 501 0.92
Sequence Information
- Coding Sequence
- ATGAGCCTACAGTGTCGCGTTTGCTTGGATTATGCCAAACATTGTACCTCACTGTTCGTCTGCACCGATGGGACAACTCTTGCACAGATCATCCAGTTTTGTGCCGATATCCAGATtgctgaagatgatgattTACCTTGCCATATTTGTCTCAAGTGTTCTGAAGATGCCAAGCTTGCCTACATGTTTGTGAAGAAATGCCGACAATCAAACAACGAGCTGCATGCGCAACATATTCTCAGCAAGCTAATAAACACCACGACTGAGGACAGATCGGACTTATCATCACCAGCAGGCAGTGAGAGACAAAGAACCTGCGAACTGTTGGTAGAGTTTGTAGTAGAGCCCACCGAGGTCGAGAAGGAAGTGCTTCAAATTGAGACACTGGACGAGCATCTAGATGAAGAAGGTGGGCATATTGCATCGCACGGCAGTACGACCGATAATGATGATTACATCGAAGCGGAGTACCTGGAGGAAAGTTCGGATCTAGACCAAACCAACGAGGACATCCGTGACTCACCTATCGTTTTCGATTGCTCTGAAGGTGATACATTCACCCGGGCGCACTACTGTTGCCATAGCGACTGCGTATTAATGTTCTACACTAAGCATGACTTAAAAGAGCATATTCACTCGCAACACGTACTTGATGTAGCGCAAGAAACACCCTCAAACGAACGGTATAGCTGCGGAAATTGTGACCAATCGTTCTTCACTGCGAGCGAACTCGACACCCACGAAGCACTGCTAGCGCTTAAAAGAAGCATCGTCAATCCAACCACCAAGGGACGCCCCAAAACCTATCCCTGCCTGTTCACTGCCGCGGAGAAGAAGTGCTGCGATTGTTACGCTCCCTTTTCAACGGTCGAAGCCCTGCTCGAGCACAGCGCCCAGCACCATTCCGTTCGCCAGACGGTGCAGGATCCGGCACGCCCTATAAGGTGCCCCGTATGCTTCAAGCTGTTTCGCTGCAAGGCAACACTCATTTTCCACCAGAACGCACCGTACAAACCGCGCAACTACCGGTGCCGGACGTGCGGGGTCGCCTACCGAACGCCCTCCCAACTTGCCACCCACGAAGCGGTCCACACGGCAGGACAGAAGTACGTGTGTGCGGAGTGCGATACGTGCTTCAAGAGCGAACACAACCTCAAATCGCATGCCCTGCTGCACCGCGAGAAGCGGGAGGTGTGCGGGACGTGCGGGATGTGCTTCCACCGGAAGTCGAACCTACGCATGCACGAACGCATCCACTCCGAGGCGTACTACTGCGTGTGTCCGCACTGCGATCGGAAGTGCAAGAACCGGTCGCAGCTCCGGGAGCACCAGAAGGTGCACACGCAGAAGAAGACGCTCGATTGCCGGTACTGTTCAAGGTCGTTCGCGTACATCAGTGACCGGAAGCGGCACGAGATGACGCATACGGGCGACTATCCGTTCGTGTGCAGTTGCTCGAAGATGTTTTCCCGGAGCCGTCTGTATGAGAAGCATGTGAGCAAGTGCAAAGTGGCAATGGACAGCCAAGAAAAGGAGATGCATTTCCTGCTACTCGTTCTCTTCCTGGCGTAG
- Protein Sequence
- MSLQCRVCLDYAKHCTSLFVCTDGTTLAQIIQFCADIQIAEDDDLPCHICLKCSEDAKLAYMFVKKCRQSNNELHAQHILSKLINTTTEDRSDLSSPAGSERQRTCELLVEFVVEPTEVEKEVLQIETLDEHLDEEGGHIASHGSTTDNDDYIEAEYLEESSDLDQTNEDIRDSPIVFDCSEGDTFTRAHYCCHSDCVLMFYTKHDLKEHIHSQHVLDVAQETPSNERYSCGNCDQSFFTASELDTHEALLALKRSIVNPTTKGRPKTYPCLFTAAEKKCCDCYAPFSTVEALLEHSAQHHSVRQTVQDPARPIRCPVCFKLFRCKATLIFHQNAPYKPRNYRCRTCGVAYRTPSQLATHEAVHTAGQKYVCAECDTCFKSEHNLKSHALLHREKREVCGTCGMCFHRKSNLRMHERIHSEAYYCVCPHCDRKCKNRSQLREHQKVHTQKKTLDCRYCSRSFAYISDRKRHEMTHTGDYPFVCSCSKMFSRSRLYEKHVSKCKVAMDSQEKEMHFLLLVLFLA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -