Adir011868.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- L
- Assembly
- GCA_000349145.1
- Location
- KB672946.1:629457-652431[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00021 0.012 15.5 3.6 1 23 175 197 175 197 0.97 2 11 0.32 18 5.5 5.7 1 23 203 225 203 225 0.98 3 11 2.6e-06 0.00015 21.5 3.7 1 23 231 253 231 253 0.99 4 11 8e-06 0.00045 20.0 0.3 1 23 259 281 259 281 0.98 5 11 2.5 1.4e+02 2.7 0.1 2 23 376 399 375 399 0.82 6 11 0.043 2.4 8.3 0.3 2 23 454 476 453 476 0.96 7 11 0.11 6.2 7.0 0.2 1 23 822 844 822 844 0.95 8 11 3.8 2.1e+02 2.1 0.5 1 23 892 914 892 914 0.90 9 11 0.00017 0.0097 15.8 0.2 1 23 959 982 959 982 0.93 10 11 0.0008 0.045 13.7 0.8 1 23 989 1012 989 1012 0.98 11 11 0.0018 0.1 12.6 1.6 1 23 1044 1066 1044 1067 0.96
Sequence Information
- Coding Sequence
- ATGGCCCTGAAGATGCTCTACCGTGGGCCGAGTACGCGATTGGAAACATTGATCGAGAAGATTCAGCAGAGCACGAACGGAGCAGGCGGTGGGAGCATGATTGCGCCCGGTGCTATAGGTGCTAGTTTCGGTGGTGTGAAGGAATTTTCCCTCGGGCAAGAACTCTACTCATCGCACACGTCCTCCAGCTTTTCGCCCTCCATTTCGGACGGTATGACAACGCCGAACTCGATCACGAACGATACGAACGACGGCTCCATGCTAGCGTTGGAGCACACCGGTGAGAAACCGTTTCGCCAGGGAGGCAATCACCCGCATCACAGTCATCCAtcgcgccatcatcatcatcttcaccatcGACGAacggcggtgggtggtggacATGCCGCGTCCGGCAAGGACGGTGGCAAGTCGTCCTCGAAGCATCATCAGcacaatcacaacaacaacaatagtaGCAACCACAATCACAATactaacagcaacaaccacgGGAGCAACAGCAAGGGCCTGAGCAGCACCTACCACTGTCAGTTCTGCGAGAAGACGTTCCCGCGGCTGGGTTATCTCAAGAAGCACGAACAgAGCCACACGGAACATATGCCATTCAAGTGTGAATACTGCGCCCGGCTgttcaaacacaaacgctcCCGTGACCGCCATACGAAGTTGCACACGGGCGATCGGCGCTACCGCTGCCTACACTGTGAGGCCGCATTTTCCAGAAGTGACCATCTGAAGATCCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGGGGCTACAACACTGCGGCCGCCCTAACCAGTCACATGCAGAACCACAAGAAGCAGCTGGCACTCACCGGCAGCCCCAACCTGACGTACAGCCCCCGCTCGACTACGAGCTCCCTGTcgagtggtggtggcagtggcggtGGTAAACGAGGTTCCAAATTCTCCTCCTACTCCAGCGACCCGTTGCTGTTGATGGGACGTGGCAGTGCCAAACTGTCGTCGTCACTAGCGAAGTCTGCGTCCGCGCACGCCTCCAGTAATCGGACTCCAACGCCCGGAAGCACTGCGGGCGCAGGCAATGGATCAGGTACGACACACCAGGATCTGCTGTCCTGTCCGTACTGCACGCGCACCGATTTCGGTACGCTCGAGCAGCTGGGAATCCACGTACAGTCGATGCACGGACACGGCACAGCGCTTGGTTTGTTGGCCGGCGATGCACCACTCTCTTACTTTGCGCCCCATTTGCGCGGCAGTCCGAGTGGAGGTGGACGCCGTGCCATAACTCCCGACGCCAGCACACTTTCGCTCGGCGGACTTGGTGGTCCGCCCTATCCGCCGATTACGTGCGAGTTCTGTACGATGAAGTTTCCAACCGTTCCGCTGATGTTTGCACACCTGAAGACATCACATCTGGATCGACTAACCGGTGCGGGAGGAGTCGCAGGACCGGGGGCAGGAGGACAGCAACGGAACTCACCGAATGGAACCGGAAGTTCAATGGGAAGCTCACGCCCACCGAGCGGTTTTCATCCACTGGACCAGCTGCACTTCAACAAGAACCTGCTCGGAACTGCTTTTCCCGCGTTCTACGGCGGAATGAGCGCCGGTTCTTCCACCAATGTGCACGGCATGACGGGTGGCATCGTAAAAGCGGAGCAGCGAGCTTGCGATGCAAATGGGCgcgatgaaaatggcaacgaaCCCGGAAACGTGCCCGGTAGAAGACGCAAACGCGCCCGAGGGGACGACGGACTCGAGGAAAGGCACCACGAAGAGGATAATTTACGCGATCGAGCAAAAGAAGACGGACATCGGGCAGACGCCGCTGCGAACGATGaagacgatgaagatgaagtggCCGATGACGATGCGATGGAGCAAAATGTATCAGCAGCCCTTAAGGAAGAGTCGGCCGAAGCGCTACAAGACACGGAATGTGCACAGATTAAGCAGGAGCGTAAGGAAGAGATAGATCGCACCGTCGCGGAGACCGCATCTGCAGCGAGTTCGGCCCGGTCGTCCCCGTGTGACTCGTTGGAATCGCATACCCGTCCCGTCAGTCATCAATCCGGTCAGAATACACCGCCCATAAGTCCGGTGGAACAGCTCACTCCGACCGATCTCAGCCAACcgaaaattaaacgatttaaGCTAGAGACGGTGGAGGATGAAGACGGTCCGGATGACGAACGGAAACCAGTGTCAGCTACCGGTCGAATCCATGATCGAGAGCATCCCAAGCCACGCTCCAGCACGGTTCGACGGGAAGGTGAGCAAAAGGAGCTACATCTTTCCGGTCAGCAGGGCAGCTCGGTTCAGCACCATCACAGTTCCTCCGCACAAATGCATCCAACGGGAGGAGGTTCCGGTGGGATGCAGTATCCTCCAAAGCTGGGCGCCCCTACCCCGAGCGGTTCGCAGCATGGACACCAACCGCCCGGTGCATATCTCTGCAACCAGTGCAATGCCGCCCTGCCAGACTTCGAATCGTTCCGCACGCATCTGAAGGCTCACCTGGAGCAGAGTGCTGCGGCCAgtgcggcggcagcggcggctgcagcagccgctATGCGACTCTCCGGTGAACACGCGCCGGCCGGTGCGGGAGTCACGAGTGCGTCCTCCTCATCCAACAATACCCTCTCGGTGACGGCCTTTCTCTGCCAACAGTGTGGCGCCACGCTGAGCTGCCAGGCGGAGTACGAGCAGCATACGATCGGCCACTACTTGGCGATGGCCGTGGAGTATCGCTGCCAGGCGGCCGGTACTGGTGCGGCCGGTTGCGGCGGTAAGACCACATTCGCGAAGGTGGAAGATCTGCACAAGCACCTGTACGAAGGACACATGCAGCTACTGTACAAATGCACCGTTTGCGGGGAAACGTTCGAATCGAAGGTGCAGGTGCAGGTACATTTTGCGGTCAGCCATTCGGTGGAGGTGAAGCTGTACCGCTGTTCCGCGTGTGCGGAGGCATTCCGTACGGAACGAGATTTTCGCCAACACATTCGAAGTCGGCACTTGACAGCTGGGGCCGTACAGTGCATGTTCTGTCGTATGGTTTGCTCCTCCGAGCTGGAGATGCACTTTCATCTCGCGTCACACGCCAGAAAGTTCAAATGTCCCGCTTGCCCGGAATCGTTCCACGTGGAGTTCCTGCTCGATCGCCATATCCAGACGCACCACAGTCAGAAAGATTCGAGTTCACCGAACCGCCGAGAGGCTAGCGTGAGCCATACGTTAACATCTGGCGCCAATACGGCCCCCAACGTTGGCGGATCGACATCATCGTCTGCGGCAAATCCGTCAACCACCACACCTTCAACAGCCACGGCCGCATCCACAACAgcaa
- Protein Sequence
- MALKMLYRGPSTRLETLIEKIQQSTNGAGGGSMIAPGAIGASFGGVKEFSLGQELYSSHTSSSFSPSISDGMTTPNSITNDTNDGSMLALEHTGEKPFRQGGNHPHHSHPSRHHHHLHHRRTAVGGGHAASGKDGGKSSSKHHQHNHNNNNSSNHNHNTNSNNHGSNSKGLSSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGKRGSKFSSYSSDPLLLMGRGSAKLSSSLAKSASAHASSNRTPTPGSTAGAGNGSGTTHQDLLSCPYCTRTDFGTLEQLGIHVQSMHGHGTALGLLAGDAPLSYFAPHLRGSPSGGGRRAITPDASTLSLGGLGGPPYPPITCEFCTMKFPTVPLMFAHLKTSHLDRLTGAGGVAGPGAGGQQRNSPNGTGSSMGSSRPPSGFHPLDQLHFNKNLLGTAFPAFYGGMSAGSSTNVHGMTGGIVKAEQRACDANGRDENGNEPGNVPGRRRKRARGDDGLEERHHEEDNLRDRAKEDGHRADAAANDEDDEDEVADDDAMEQNVSAALKEESAEALQDTECAQIKQERKEEIDRTVAETASAASSARSSPCDSLESHTRPVSHQSGQNTPPISPVEQLTPTDLSQPKIKRFKLETVEDEDGPDDERKPVSATGRIHDREHPKPRSSTVRREGEQKELHLSGQQGSSVQHHHSSSAQMHPTGGGSGGMQYPPKLGAPTPSGSQHGHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAAASAAAAAAAAAAMRLSGEHAPAGAGVTSASSSSNNTLSVTAFLCQQCGATLSCQAEYEQHTIGHYLAMAVEYRCQAAGTGAAGCGGKTTFAKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEAFRTERDFRQHIRSRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKFKCPACPESFHVEFLLDRHIQTHHSQKDSSSPNRREASVSHTLTSGANTAPNVGGSTSSSAANPSTTTPSTATAASTTA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -