Adir009848.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- Gzf1
- Assembly
- GCA_000349145.1
- Location
- KB673423.1:3917001-3919269[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 1.7 95 3.2 0.0 2 16 17 31 16 33 0.88 2 14 4 2.3e+02 2.1 0.0 1 11 70 80 70 87 0.77 3 14 1.9 1.1e+02 3.1 1.4 2 23 200 222 200 222 0.93 4 14 0.00062 0.035 14.1 0.2 1 19 232 250 232 253 0.95 5 14 0.00068 0.038 13.9 3.3 1 23 260 283 260 283 0.93 6 14 0.11 5.9 7.0 0.3 2 19 376 393 375 395 0.82 7 14 1.6 91 3.3 2.1 3 23 414 436 410 436 0.88 8 14 0.076 4.3 7.5 0.3 2 20 459 477 458 479 0.93 9 14 0.0045 0.25 11.3 4.2 1 23 486 509 486 509 0.96 10 14 6.3e-07 3.5e-05 23.5 0.7 1 23 516 538 516 538 0.97 11 14 0.0033 0.18 11.8 0.1 3 23 546 569 544 569 0.93 12 14 1.1e-06 6.4e-05 22.7 4.5 1 23 575 597 575 597 0.99 13 14 1.1 60 3.9 1.2 1 23 603 628 603 628 0.90 14 14 0.56 31 4.8 1.0 1 23 634 657 634 657 0.93
Sequence Information
- Coding Sequence
- ATGGCACCAGCAAAACCGCATATACTGGACTCCAGTGGAAATGCCTTACAATGTCGCGTTTGCTACAAAACCCTTCGAACGGCGAGGGCGCTGCACATATTCTCGCTACCGGACGAAACCAACGTGAACGAAGCATCTAGAACTATCGCGGAGCTGCTGGCCGAGTTTGCCGATGTTACGATACGCTACTCCGACGACCGCTCGAAATACATCTGTCCAGTTTGCTTTAAAGCTCTAGATAATGGCATTCAGCTGCGGCAGCAGATTCGCGCCAGTGAGAAAGTTGTATCTACGATGCTGCAATCGATCGAGGTTCAGAACGTCCCAGACCAGGAGTATGATTTCGAATATCTGGAAGAGTTCAAAGATGAGATTGCAATCGAAATTCTTCCACCGGCGTGCGATTCACCCGGGACCGAAGGTGAAGATGAACTGCTGGCCAAGCAGCTAAACTCCCAACTGGCCGAGGAAGAAATCGACTCGCTCGAGGATGGGTTGCGCGAGCAGGGAAAGTTTGCGTTCGTAATGCCCGCCGCCGAGCTCATCGCGAATCGTATCGAGTTTGATGATTTTGAATACTTAGAAATTCGTGGCGAACGTTGCTGCGGCTGTGCGCACATTGCGACGTCCCGGGACGAGCTGATGGCACACGCGAAGGAAAAGCATTCGCAGAACTACTACGCGGACAGTAGCTACACGTGCCCGACGTGCTATCAGAAGTTTGCGACGGCGGAAGCGCTGGAAAAGCACAACCAATACTACCTGTACAGTGATGTGTTCCTGTGCACTATTTGCCAGGAGGCGTTCAACTTCCAGAGTCATTTGATGCTGCACTTGAAGGCATGCCACGGACATGTCACGCCGGACGACGAGGTACAGGAAGCGGACGACGAGACGCCCAAACGAAAGACCCACTGGAAGGCAAATGGAACACCTGCCGATCCCATCGTACTTCCGGATGTTCAGTTCATTAAGGAAACACGAGAATTTCCGCTGTATCGATTATATACAGTGTCGGGCGAACGTTGCTGTGCCTGCAGGCTTTACCCTACCTCACTTGAGGCTCACGCCGCTGAAATTCATCTCGAGTTGGCGGACGTACTGGAACCGTGCTCGGACGACCTGCGATGCAACATTTGCCAGCAAAAGTTCACATCCCATCAGGACCGAGTGTTGCACGAAGAGGAACGCAGAGATCTGAAGCTAATCTATCAATGTGAGGTAGACtatttgtgctgctgctttatGCGCTGCAAAGAGGAGTACGTCACCGAAACGGAGCTGCTCGAGCACGCCCGGCAGGTGCACGACGggcgcagaaaagaaaacgaaagcaaactgACCCAACACGGGTCGGCGGTGGATGAAGCGCTGGTCTGTCCCATCTGCCGACGTTTGTTCGACACGCGCGAGAAGGTTCACAAGCATCGTGCCTACAAACTCGCCCTCTGCAAGCACACCTGCCGCCAGTGTGCACGCGTGTTCATGAAAGCTAGCACCCTCCGGCATCACCAGCTTCGCGAACACCTGAATCTCGAACCGGAGTTCGCGTGCGACGTGTGCGGAAAACAATACGTCACCCGTTCGACGCTGACCAAACATCGGCGGGTGCACGAACCGTCGAAAAATGTTCCCTGCTCGATCGCCGGCTGTGAGGCACGGTTTCGCGACGAGTCGCTGATGCAGCGACACTACCGAAACGTGCATAGGGAGCTGAAGGCGTACACGTGTACGCACTGCCAGAAGTCGTTCCGCACGAAGGAATCGCTCGACATACACCAACGCAGTCATACTGGCGAGCGTCCGTTCGCGTGCCGGTTCGAGGGTTGCACCAAGCGATACGCTCACGGGACGGACCGGAAGCGGCACGAACGAGCGGCGCACACGGGCGAAAAGCCACACACGTGTTCGGTGTGCAAGGCAGGTTTTCTGCGTAAGCGAGAGATGCGGCTGCACGCGGAGAAAGTGCACTGA
- Protein Sequence
- MAPAKPHILDSSGNALQCRVCYKTLRTARALHIFSLPDETNVNEASRTIAELLAEFADVTIRYSDDRSKYICPVCFKALDNGIQLRQQIRASEKVVSTMLQSIEVQNVPDQEYDFEYLEEFKDEIAIEILPPACDSPGTEGEDELLAKQLNSQLAEEEIDSLEDGLREQGKFAFVMPAAELIANRIEFDDFEYLEIRGERCCGCAHIATSRDELMAHAKEKHSQNYYADSSYTCPTCYQKFATAEALEKHNQYYLYSDVFLCTICQEAFNFQSHLMLHLKACHGHVTPDDEVQEADDETPKRKTHWKANGTPADPIVLPDVQFIKETREFPLYRLYTVSGERCCACRLYPTSLEAHAAEIHLELADVLEPCSDDLRCNICQQKFTSHQDRVLHEEERRDLKLIYQCEVDYLCCCFMRCKEEYVTETELLEHARQVHDGRRKENESKLTQHGSAVDEALVCPICRRLFDTREKVHKHRAYKLALCKHTCRQCARVFMKASTLRHHQLREHLNLEPEFACDVCGKQYVTRSTLTKHRRVHEPSKNVPCSIAGCEARFRDESLMQRHYRNVHRELKAYTCTHCQKSFRTKESLDIHQRSHTGERPFACRFEGCTKRYAHGTDRKRHERAAHTGEKPHTCSVCKAGFLRKREMRLHAEKVH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -