Adir005956.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- grau
- Assembly
- GCA_000349145.1
- Location
- KB672491.1:6667981-6672234[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 6.2 3.5e+02 1.5 0.1 3 11 201 209 199 213 0.58 2 16 3.8 2.1e+02 2.1 0.1 9 23 226 241 224 241 0.85 3 16 0.024 1.3 9.1 1.7 6 23 250 267 250 267 0.99 4 16 0.043 2.4 8.3 1.0 1 23 273 296 273 296 0.87 5 16 0.00021 0.012 15.5 1.5 1 23 304 326 304 326 0.96 6 16 0.01 0.57 10.2 0.4 3 23 336 356 334 357 0.93 7 16 3.1 1.7e+02 2.4 0.0 2 21 413 432 412 435 0.86 8 16 2.6 1.5e+02 2.6 0.9 6 23 445 462 445 462 0.88 9 16 1.9e-05 0.0011 18.8 0.8 1 23 468 491 468 491 0.96 10 16 9.2e-05 0.0051 16.7 2.7 1 23 499 521 499 521 0.95 11 16 3.9e-05 0.0022 17.8 1.4 2 23 530 552 530 552 0.97 12 16 0.00086 0.048 13.6 0.2 2 23 559 580 558 580 0.96 13 16 1.4 79 3.5 8.2 1 23 590 613 590 613 0.96 14 16 0.00065 0.037 14.0 1.9 2 23 620 641 619 642 0.94 15 16 5.3e-05 0.003 17.4 1.9 1 23 648 670 648 670 0.97 16 16 0.02 1.1 9.3 1.4 1 23 676 699 676 699 0.91
Sequence Information
- Coding Sequence
- ATGGAGACGGAGAGCGACGTAAATCAGCCGGCTTGCGAAGAGCTGTGCGTGCTGTGTCTGCTGGAAAGCAACGAACGGCATTCCCTAGCCGAGCAGACGAACGTGTGCCATGGTTCGATCCTGGACGCGCTGTGCAAACACTTTTGGATCACGGAAACTGGTTGCCGGGGGCGCTACGTCTGTGCCGCGTGCTGGGAGATGCTGTACCCGTTTCACAAATTCTACATCGAGATCGAACGACTGCACGCCGCCAAACTGCCGGCCAGGATCAAGCGGGAGCAACATTCCACCGGCcaggacgaggaggagcacTTGCCGCAGCACGGCAGCACCATCCAGTTCGAGGCACTGCACGATGCGAACGGGTTCATCACGAGCCTGAACGAGGTGTACGTGAAGGAAAGCTACTCCCACAGCGAGTCGGACGGTACGAACGGGGACGACGGGTCGGACGCTGACTCGGACGTGCCGTTATCGGAGCTGCGGAAGGCAGCTGCCGGTAACGGCAGGGTAGCGCGCTCCTCGCAGCACACCTCCGCACTGTTCGACGGTATCGGCCTGTCGCTGTGCCGCatcaacgaaaacaaactccagATCGTGTGCCACGAGTGCTTCCGCCAGTCGAAGCGGGCGGCCGACGAAGCGGTCGATaacgacgagctgctgcaggacgCCACGTACTACACGTTCGCCGGGTTGATGAAGCACTACCGCAAGGAGCACCGGACGGCCGGCTACGCCGTGTGCTGCAGTCGCAAGTACACGCGGCGCCGCACGCTCAAGATACACGTGCGATCGCACGGGAAGCGTGTGGTGCACCGGTGCCTGCCCTGCGGGATCAAGTTCCGCAAGCAGGAGTCCCTGAACGACCACAACCTGCTGATGCACACGGCGGAGGAAGCGAAGCAGCACAAGTGCGACAAGTGCAGCAAGGCGTTCGCTACGGAGGACCTGCTGAGCTCGCACCGCACCTGGCACGAGAACGTCGAGCGGAAGAACATCGCCTGCAACGTCTGCAACGTGTTTTTCGCCAGCTTCCCTGCGCTGGAGAAGCACCGCACGCTGCACCACCCGGGACCGGACGGGCCGGAGGGAACGGCGTCGCTGTCGCCGGCCGATCCGCACGGCACGCCCGACCCGACGGACGACAAGCTGACGGAGTCGCAGTACCGGACGCGCGTCTCGGCGGAGGAGATCAGCGCCCAGGACGAGTTCATCAAGCGCTACTGCGTGCTGAGCTGCGCGCAGTGCGACTACATCGCGGACACGTTCGCGCTGCTGCGGCAGCACGCGACGGACGCGCACGAGGCGCGCACGAGCGAGGTGCTGTGCTGCGACCGCACGTACAGCAAGCGCCAGTCGCTGTACGAGCACTGTCTCGTGCACGAGAACCCGGactgcttccggtgcggcgTGTGCGGCAAGCAGTACTCGAGCAGCCGGAGCCTGCAGGCGCACAAGACGCGCATCCACACGCCCGCAGCCGAGCGGCCGTTCTGCTGCGAGGTGTGCGGCGAAACGTTCGTCAAGTCGTACCTGCTGATGCAGCACATGGTGCACCATCtggcgaagcagaagaagctgAACTACTGCAGCGAGTGCCAGCGGTCGTTCACGACCGCGCGCGTCCTCAAGAACCACCAGCAGACGTACCACGGGGCGAGCTTCAGCTGGATCTGCGACGTGTGCGCGAAGGGCTTCAACAGCCGGCCGCAGTTCGAGAACCACCGGCTGACGCACTCCGTCGAGGGCAAGACGCAGCTCAAGCACCAGTGCGAGGAGTGCCACAAGTGGCTGCGGAACAAGAAGTCCTACCAGCAGCATCGCATCCGCTGCCACGCCAACACCGGCCCGGTCAGCTGCCAGTTCTGCGGCAAGAAGTCGGTGAACGCGAGCGCCCTGCAGTCGCACATCCACCTGCACCACGTCGAGCGCCCGGACTATCCCTGCAAGTACTGCAAGAAGAGCTTCAAGACGTCGCTGCGGCTGCGCGAGCACGAGGCGAcgcacaccggcaccgtccTCTACCGGTGCCCGTGGTGTCCGCGCACCTTCGCCTGCGGCTCCAACATGTACAAGCACAAAAAGGCGGGCCACCCGAGCGAGTGGGCGGCCTCGGTGAACAAGCGGTTCGGGGAGCGATGA
- Protein Sequence
- METESDVNQPACEELCVLCLLESNERHSLAEQTNVCHGSILDALCKHFWITETGCRGRYVCAACWEMLYPFHKFYIEIERLHAAKLPARIKREQHSTGQDEEEHLPQHGSTIQFEALHDANGFITSLNEVYVKESYSHSESDGTNGDDGSDADSDVPLSELRKAAAGNGRVARSSQHTSALFDGIGLSLCRINENKLQIVCHECFRQSKRAADEAVDNDELLQDATYYTFAGLMKHYRKEHRTAGYAVCCSRKYTRRRTLKIHVRSHGKRVVHRCLPCGIKFRKQESLNDHNLLMHTAEEAKQHKCDKCSKAFATEDLLSSHRTWHENVERKNIACNVCNVFFASFPALEKHRTLHHPGPDGPEGTASLSPADPHGTPDPTDDKLTESQYRTRVSAEEISAQDEFIKRYCVLSCAQCDYIADTFALLRQHATDAHEARTSEVLCCDRTYSKRQSLYEHCLVHENPDCFRCGVCGKQYSSSRSLQAHKTRIHTPAAERPFCCEVCGETFVKSYLLMQHMVHHLAKQKKLNYCSECQRSFTTARVLKNHQQTYHGASFSWICDVCAKGFNSRPQFENHRLTHSVEGKTQLKHQCEECHKWLRNKKSYQQHRIRCHANTGPVSCQFCGKKSVNASALQSHIHLHHVERPDYPCKYCKKSFKTSLRLREHEATHTGTVLYRCPWCPRTFACGSNMYKHKKAGHPSEWAASVNKRFGER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -