Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB673423.1:3910922-3914173[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.4 1.9e+02 2.3 1.0 2 23 191 213 191 213 0.92

2 17 0.0003 0.017 15.1 0.2 2 21 223 242 222 243 0.95

3 17 0.07 3.9 7.6 2.4 1 20 250 269 250 271 0.93

4 17 4.7 2.7e+02 1.8 2.4 2 23 393 415 392 415 0.91

5 17 0.061 3.4 7.8 0.0 2 20 426 444 426 446 0.94

6 17 0.046 2.6 8.2 3.8 1 20 453 472 453 474 0.94

7 17 0.57 32 4.7 1.1 3 23 556 577 555 577 0.92

8 17 0.4 22 5.2 0.1 1 19 590 608 590 610 0.94

9 17 0.00045 0.025 14.5 0.2 1 21 620 640 620 645 0.95

10 17 0.045 2.5 8.2 0.9 2 23 704 728 703 728 0.87

11 17 0.78 44 4.3 0.7 2 20 745 763 745 765 0.93

12 17 8.8e-06 0.00049 19.9 0.3 1 23 772 795 772 795 0.93

13 17 2.9e-07 1.6e-05 24.5 0.1 1 23 802 824 802 824 0.98

14 17 9.5e-05 0.0053 16.6 0.3 1 23 830 853 830 853 0.95

15 17 1.1e-05 0.0006 19.6 2.1 1 23 859 881 859 881 0.98

16 17 0.13 7.4 6.7 4.1 3 23 889 910 887 910 0.92

17 17 0.0014 0.079 12.9 4.4 1 23 916 938 916 938 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.4	1.9e+02	2.3	1.0	2	23	191	213	191	213	0.92
2	17	0.0003	0.017	15.1	0.2	2	21	223	242	222	243	0.95
3	17	0.07	3.9	7.6	2.4	1	20	250	269	250	271	0.93
4	17	4.7	2.7e+02	1.8	2.4	2	23	393	415	392	415	0.91
5	17	0.061	3.4	7.8	0.0	2	20	426	444	426	446	0.94
6	17	0.046	2.6	8.2	3.8	1	20	453	472	453	474	0.94
7	17	0.57	32	4.7	1.1	3	23	556	577	555	577	0.92
8	17	0.4	22	5.2	0.1	1	19	590	608	590	610	0.94
9	17	0.00045	0.025	14.5	0.2	1	21	620	640	620	645	0.95
10	17	0.045	2.5	8.2	0.9	2	23	704	728	703	728	0.87
11	17	0.78	44	4.3	0.7	2	20	745	763	745	765	0.93
12	17	8.8e-06	0.00049	19.9	0.3	1	23	772	795	772	795	0.93
13	17	2.9e-07	1.6e-05	24.5	0.1	1	23	802	824	802	824	0.98
14	17	9.5e-05	0.0053	16.6	0.3	1	23	830	853	830	853	0.95
15	17	1.1e-05	0.0006	19.6	2.1	1	23	859	881	859	881	0.98
16	17	0.13	7.4	6.7	4.1	3	23	889	910	887	910	0.92
17	17	0.0014	0.079	12.9	4.4	1	23	916	938	916	938	0.99

Sequence Information

Coding Sequence: ATGCAACGATCttcgaagcgaaaaaaagtgtcCGATCCCAAAGAGGGCGCGATGCGGTGTTGCTGCATCTGCTCCAAACAACCTACGGAATCTTTACTCGAACTGGCAACAGTTGTTGTAAAAAGCAACGCAACAACGATTGCCGATATAGTCGAGCAAGTGGCTGGCATAAAAGTAAAGCACGTGCAGCAAAGCATTTGCAGCGTTTGCTGGAGCAAGATAAAGGCAGCCTACACAATACAGAACGAAATTCGTGGCTCGCGATGCATTTATGACGGCACGAAAGAGGAGGCTGAAAGCGATGAGGAGTCAAGCGGGGTAATAAATGTGGACCTGGGCGTGAAAGATGAATCCGTGGAGTGTGAATATTTGATCGAATATCTCGAATCAGACGCAGACGATTCGCAGCAGCGGGACGAAGTAGAAGATGTTGACCACGAACGGCGCGTCATTGAACGGAAAGAGAAAGCGCCGAGTAAAGTAACCCGCCAGTTCGAGATGCCTCGCCTAACGTCGATCGTGAAGGATGTGCTGTACGGGCAGTACCGAGCGCTGGAAGTGTCGGGCGAACGCTGCTGTGGTTGCAGTTTCGTGGCTGAAACGCGCAAGGAACTATTGCAGCACTCGGAAATGGTGCACGCCGTCGAGATAAAGGATTGTGGCGATTACTGTCCGATCTGTTTCTACAAATTCTCTTCCGATCGACAGCTCGAACGACATATCCGCGAGTTTCAGCAGGCGACGATGTTCGTCTGCCTGCGCTGCAATCGGTTCTTCAATCGACATAGTAGGCTCGTCACCCACTTTCTGCGCTGCGGGGAAAAGGTGGCTACGGACCTGTGTTTAAGTGAAATCGAAGACACGGAATCGCacgacgaagaggaggagggtGTGCAAGAGCAGGAGTTGGAGGATGCCGAGAGTGGCGAGTATTACTTTCCCGAACAGGTCAATCAAACTGGTCGGGATACGTTCGGCGGAACGAGTGAAGATCGCCCTCAGAAAACACTATCCGACCCGCGGATGATGCACCGCTATCGGACGaagtttgaagaaatatttgcCAACGAAGAACTCTCCTGCGAACTGAACGAGGAGGGGTTGAACGTGCATGAAATACAGATTGCTACGCAGCAATCGTTTGAAACGTTCAAATTCGTCCGTCTGCGTGGTTTACGGTGCTGCGGATGTAGCTATACGTGCTTCTCCAGTGCGATGATGATCGAACACGGGAAGCTGGTGCATCTGGCCGAGGAAAGCTCCGGAGACGCTCGAACATGTGGGCTGTGCGGTGTACAGTTCTCGGACGAGCTGGAGCTCGTCAAACATCTGAGCTTTTTCACCACCAAACAGTTGTTCTTCTGTACGGTTTGCGATGAATCGTTTCTTACGCATGACAGCTTGCGACACCATCAGACACATAAcgaacggcaccggcagcttCAGCTCGACAAGTATCAGCAGGCGGGCGTTGAAATGATCGAGACGGATGCGTTCATCGAGCTCGACCAGCAAGACGTGGCGGATGAGCTACATAagctgctggcggagaagGTCACGTACCGACCAAAGTTTGTACGGAACATTGCAATGCCTGAGGACCGTTTCATACTGGGCGTGGAGGAGTACAACAACTACCGGATCCTTAACGTCCAGGGAGAGAGTTGCTGCGGGTGTGCCCGACTATTCGATTCCGTGGCGGACCTCAAGCGGCATTCCAAACTGGAGCACTACCTGCCACTGGTATCGAGTGGCCGTTCCTACGGACACCAGTGCGATATCTGTTACGCCGTGTTTGACTTTGAGCGTGGGCTTATCGTGCACAACGCTATAAGACGTGCGGGTAGGAAGCGGCTCTTTGTATGCAAGCTGTGTGGGTTGCTGTTCTCCAAAAAGTTCGGACTCGCACGACACATGCAACTGGCACCGAACCATCTGTCGCGGTTGATTGTGGATGCGGAGCGAAACGGAGACGATTCCGAGGCGTCGTGCAgtggtgcagctgcagccgatCCCGTCGAATCGGATCCACGCGTGCAAGAGGCATTACAGTTGCACCGTTCGGTAGAGGAGGCAGGAGTGGAAAAGGTGGGTCATCTCGTTTGGTTCCACTGCTGTCTGCCCAAGTGCCCGGAAATGTTCACCGAAGAGGAGGCCCTGCTGGAGCACACACGAGAAGAGCACAACGGACGGCGCAGGGAAAACGAGGTGGAACGCAAGCAGCACGCAAACGTGTGTCCCGGCTGCTGCAAATCGTTCCAATCGTTGCCCAAGCTGATGTGGCACCGCTTTCAGCGGTTTGTGCCGCGCCAGTACGATTGCAACCAGTGTGGCAAGGCGTTCAACAGGTGGTCCAGGCTGAGGGAGCACGTCGAACAGGAGCACAGCGAATCGCCACCGCGCTTCGAGTGTCCGGAGTGCGGGAAGGCGTTCGTGGTACGTTCGCGGCTGAAGGCTCACATGCAGATACACAGCAACCGGAAGGACCACGTGTGCGATGTGTGCGGCGATGCATTCGTCAACAAGGGACTGCTGAAGCGCCATCGCCGCGCGCTTCACTCGACGGAGTTGCTGTTTGAGTGTAAGCACTGCACGAAGAAGTTTGCAGTGGCGGAGAAGCTCAAGATCCACCAGCGAGTGCACACCGGGGAGCGGCCGTACGGATGCGGTTTTTGCCATCGAACGTTCAGTCACTACACGGACCGGAAACGGCACGAAATGGCGTCCCACACGGGGGAGCGACCGTACAAGTGTGAGCACTGCCCATCGACGTACATACGCAAGCATGAGCTGGTGATGCACACGCAGAAGCATGCGACTGGGGGCAGCAGCACAAGCGCTGGGGATGTTcgggaggaagcgaaaaaaagttgGTAG
Protein Sequence: MQRSSKRKKVSDPKEGAMRCCCICSKQPTESLLELATVVVKSNATTIADIVEQVAGIKVKHVQQSICSVCWSKIKAAYTIQNEIRGSRCIYDGTKEEAESDEESSGVINVDLGVKDESVECEYLIEYLESDADDSQQRDEVEDVDHERRVIERKEKAPSKVTRQFEMPRLTSIVKDVLYGQYRALEVSGERCCGCSFVAETRKELLQHSEMVHAVEIKDCGDYCPICFYKFSSDRQLERHIREFQQATMFVCLRCNRFFNRHSRLVTHFLRCGEKVATDLCLSEIEDTESHDEEEEGVQEQELEDAESGEYYFPEQVNQTGRDTFGGTSEDRPQKTLSDPRMMHRYRTKFEEIFANEELSCELNEEGLNVHEIQIATQQSFETFKFVRLRGLRCCGCSYTCFSSAMMIEHGKLVHLAEESSGDARTCGLCGVQFSDELELVKHLSFFTTKQLFFCTVCDESFLTHDSLRHHQTHNERHRQLQLDKYQQAGVEMIETDAFIELDQQDVADELHKLLAEKVTYRPKFVRNIAMPEDRFILGVEEYNNYRILNVQGESCCGCARLFDSVADLKRHSKLEHYLPLVSSGRSYGHQCDICYAVFDFERGLIVHNAIRRAGRKRLFVCKLCGLLFSKKFGLARHMQLAPNHLSRLIVDAERNGDDSEASCSGAAAADPVESDPRVQEALQLHRSVEEAGVEKVGHLVWFHCCLPKCPEMFTEEEALLEHTREEHNGRRRENEVERKQHANVCPGCCKSFQSLPKLMWHRFQRFVPRQYDCNQCGKAFNRWSRLREHVEQEHSESPPRFECPECGKAFVVRSRLKAHMQIHSNRKDHVCDVCGDAFVNKGLLKRHRRALHSTELLFECKHCTKKFAVAEKLKIHQRVHTGERPYGCGFCHRTFSHYTDRKRHEMASHTGERPYKCEHCPSTYIRKHELVMHTQKHATGGSSTSAGDVREEAKKSW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -