Adir012172.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- -
- Assembly
- GCA_000349145.1
- Location
- KB672713.1:3186709-3189021[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0025 0.14 12.1 1.5 1 23 98 121 98 121 0.96 2 13 0.12 6.5 6.9 3.3 1 23 129 152 129 152 0.93 3 13 0.0019 0.11 12.5 5.7 1 23 158 180 158 180 0.98 4 13 0.28 16 5.7 4.4 1 23 211 234 211 234 0.96 5 13 0.093 5.2 7.2 0.0 1 23 241 267 241 267 0.95 6 13 0.00046 0.026 14.5 1.9 1 23 383 406 383 406 0.94 7 13 1.3e-05 0.00072 19.3 0.4 2 23 412 433 411 433 0.96 8 13 0.00077 0.043 13.8 4.4 1 19 474 492 474 493 0.97 9 13 0.00011 0.0064 16.4 1.3 2 23 527 548 526 548 0.96 10 13 1.4e-07 8e-06 25.5 0.6 1 23 554 577 554 577 0.97 11 13 1.6e-05 0.00089 19.1 3.7 1 23 583 606 583 606 0.98 12 13 0.0042 0.24 11.4 2.0 3 23 614 635 612 635 0.95 13 13 9.2e-05 0.0052 16.7 2.3 1 23 640 663 640 663 0.95
Sequence Information
- Coding Sequence
- ATGAAGCAGCTGATTGGAACCAACGATTGCAAATGGTGCAACAAATGGACGGACGATTCGAAAGAAATGGATGCATGGGTGGTAGTGGCTGGAAAGGATGTGACAATACGAGCTATGATTGAAATCTTCCATCTTCCCGAGtATATACACATAGACCACAATGATCGCATCTGTGCTCCGTGCGTGGGTCAGTTGGAGGAATGCTATAGCTTCTACAACACACTTCTTGCCACACTACTCAAGGCATGCAACGCGTCCAGCGAACAAATTCCGCCCATTCCGGAGGGTTCTTTCCCGTGCGCTGTATGCGACCACTCGTTCGCCACGAAActggagcgaaaaaagcatcTCAAATTGCAACATTCGCAACCCAGCCACCCGTACTACCACTGTCAGCCGTGcgaaaaatcattcaaaactaACCGAGGCATGCTGCAGCACAAAACAATGTATCACGACGCGCCTGAAACGTACTCCTGCCACTTGTGCGAGCGACAGTTTCTCACCAAAACCAACTACCGTAACCACATGCGCTACCACAAGGATCATGTGTGTAGCTTCTGCAACAGTGGCTGGCTCGGCGAGCCGAAGCTGCTCGAGCACGTACGAACGGCACACCCGGACCGGATGTTCGTTTGTCGGTTCTGCGACAAAAAGGAACGGATGAAAAAATGTCTCAACCGTCATCTTCGCGCTAGCCATCGGCAGCAGGCCAACCCGTACTACTGTGGGTACTGTGGAAGTGGGGCTCTCGCGTTCGAGAGCTACGAAGCTCTGTTGGACCATTTGCGTGGGCAGCACAGCGACGGTGAGCAGCACGAGAAAGAACCATACGAAACGCTGCTGAATGATGCGTTGTTCGTCAAAGAGCTAGAGCTGCCGGAAGCGCACGAGCCGGACCGAGAGCAGGAGcaatttttgcataatttccaCCTCGTCCGGAGTGGGCCGGAAAAACCGGACCTCTCCCAGCCGGTGGAGCTGCGGATCGATCGACGGATGGTGCTGGAGGACTTTCTGGACGAAGCGTTCGAGAACGACGAAATCTGGAACAAATACATCGAAAATGGGGAGGAGTATCTGATCGATGATTACGATATCTATCTTCGGGGGATGGAAGGTAACACGGAGCCGGAACCGTGTCGATATCGGTGTCCCCAGTGCGAAAGGGGATTCCAGAAACAGCACCATCTGTCCATCCACCTGGCGGAGGAGCACGACGTGGCCAGTCTGGTTTGCAACGATTGTGGAGCAAGTTTTACGCGCATCTCGCTCTACCGAACTCACCGGCGCGAGCATCTGAAGGAGAATGTTCGCTTTCGCGAAAGCAACATCCCCGAGATGGAGGAAGCACTGTCGCTGGTACAAAGCTCTGCTCCACTGGACTATTCGGTGCACGAGACGGAGCACGGGTACCGGTTCGCGTGTAATCTGTGCGACCGTACCTTCCAGCGGAAGCACAACCTTGAGAAGCATTGCTGTGCGTTCTATGAACGTCACGGCCAGCAGGACACCGACCAGAAGGCGACAAGCTCCACCGCAAGCGCACTAAACACGGCCTCGAACGAGGAAATCATCTACTGCATGCTGTGCGATCGTCGGTTTAGTTCAACGTCCGGGCTAAAGTATCACTTGAAGCGACACACGGGCATCAAGGCGTTCACGTGTTTGTACTGTGGCAAAAAGTTTACCGCCAACTCGAACCTGAACGCGCACATTCGCAATGTGCACAGCGAGCGGAAGGATTATCGGTGTGCGGAGTGCGCCGAATCGTTCGCAACCAAGGATCATCTCAACAAGCATCACCGGTCGCGCCATCGGCAGGAACGGACGTTTGGATGTGGCGAGTGTGGAAAGAGCTACCTGCAACGATCGCATCTGAACGAGCATGTGGCATCGTGTCACCGGGAGGATCGCTACCTCTGCACCGTTTGCAATAGTTCTTACGTTTCGAAAAGCACACTGAAACGACATCAGCAGAAGAAGCATGGCATTTCGTGA
- Protein Sequence
- MKQLIGTNDCKWCNKWTDDSKEMDAWVVVAGKDVTIRAMIEIFHLPEYIHIDHNDRICAPCVGQLEECYSFYNTLLATLLKACNASSEQIPPIPEGSFPCAVCDHSFATKLERKKHLKLQHSQPSHPYYHCQPCEKSFKTNRGMLQHKTMYHDAPETYSCHLCERQFLTKTNYRNHMRYHKDHVCSFCNSGWLGEPKLLEHVRTAHPDRMFVCRFCDKKERMKKCLNRHLRASHRQQANPYYCGYCGSGALAFESYEALLDHLRGQHSDGEQHEKEPYETLLNDALFVKELELPEAHEPDREQEQFLHNFHLVRSGPEKPDLSQPVELRIDRRMVLEDFLDEAFENDEIWNKYIENGEEYLIDDYDIYLRGMEGNTEPEPCRYRCPQCERGFQKQHHLSIHLAEEHDVASLVCNDCGASFTRISLYRTHRREHLKENVRFRESNIPEMEEALSLVQSSAPLDYSVHETEHGYRFACNLCDRTFQRKHNLEKHCCAFYERHGQQDTDQKATSSTASALNTASNEEIIYCMLCDRRFSSTSGLKYHLKRHTGIKAFTCLYCGKKFTANSNLNAHIRNVHSERKDYRCAECAESFATKDHLNKHHRSRHRQERTFGCGECGKSYLQRSHLNEHVASCHREDRYLCTVCNSSYVSKSTLKRHQQKKHGIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00100441;
- 90% Identity
- -
- 80% Identity
- -