Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB672813.1:671787-675227[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.0018 0.1 12.6 3.5 1 20 143 162 143 165 0.93

2 17 5.5e-05 0.0031 17.4 1.4 2 23 227 248 226 248 0.97

3 17 0.75 42 4.4 4.7 1 23 255 278 255 278 0.79

4 17 6.4e-06 0.00036 20.3 2.8 1 23 292 314 292 314 0.97

5 17 0.13 7.4 6.7 4.0 3 23 322 343 320 343 0.96

6 17 3.7 2e+02 2.2 0.2 1 23 460 483 460 483 0.90

7 17 2.3e-05 0.0013 18.6 0.6 1 23 511 533 511 533 0.90

8 17 1.2e-05 0.00069 19.4 1.4 1 23 539 562 539 562 0.98

9 17 0.08 4.5 7.4 2.7 1 23 571 594 571 594 0.97

10 17 6.6e-05 0.0037 17.1 2.3 1 23 748 770 748 770 0.95

11 17 0.018 1 9.4 2.8 1 23 776 799 776 799 0.95

12 17 0.009 0.5 10.4 0.9 1 23 810 833 810 833 0.97

13 17 9.3 5.2e+02 0.9 2.7 1 14 859 872 859 882 0.76

14 17 2.6 1.4e+02 2.7 5.1 2 23 900 921 899 921 0.95

15 17 3.7e-06 0.00021 21.1 2.3 1 23 946 968 946 968 0.98

16 17 0.0005 0.028 14.3 0.2 1 23 974 997 974 997 0.96

17 17 0.0015 0.084 12.8 0.9 2 23 1013 1035 1012 1035 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.0018	0.1	12.6	3.5	1	20	143	162	143	165	0.93
2	17	5.5e-05	0.0031	17.4	1.4	2	23	227	248	226	248	0.97
3	17	0.75	42	4.4	4.7	1	23	255	278	255	278	0.79
4	17	6.4e-06	0.00036	20.3	2.8	1	23	292	314	292	314	0.97
5	17	0.13	7.4	6.7	4.0	3	23	322	343	320	343	0.96
6	17	3.7	2e+02	2.2	0.2	1	23	460	483	460	483	0.90
7	17	2.3e-05	0.0013	18.6	0.6	1	23	511	533	511	533	0.90
8	17	1.2e-05	0.00069	19.4	1.4	1	23	539	562	539	562	0.98
9	17	0.08	4.5	7.4	2.7	1	23	571	594	571	594	0.97
10	17	6.6e-05	0.0037	17.1	2.3	1	23	748	770	748	770	0.95
11	17	0.018	1	9.4	2.8	1	23	776	799	776	799	0.95
12	17	0.009	0.5	10.4	0.9	1	23	810	833	810	833	0.97
13	17	9.3	5.2e+02	0.9	2.7	1	14	859	872	859	882	0.76
14	17	2.6	1.4e+02	2.7	5.1	2	23	900	921	899	921	0.95
15	17	3.7e-06	0.00021	21.1	2.3	1	23	946	968	946	968	0.98
16	17	0.0005	0.028	14.3	0.2	1	23	974	997	974	997	0.96
17	17	0.0015	0.084	12.8	0.9	2	23	1013	1035	1012	1035	0.94

Sequence Information

Coding Sequence: ATGGAACCGGAGCAGGAACCCGAACCGGTCGTCGATGACGATCCGGTGGACGTCCCAAATCAAAACCCCGAATCATACTGCCGGTTCTGTTTCTCTGAGAATGAAGTGGAACCGCTGTTTTCGGCGAACGGAACCCAGGCGAGTGCGGATCTGCTGGATCGCATCTACGACTGCATCGGCATAAGACTGACGAAGCGCGAATACTGCCCCAGCGGCATTTGCTGGTCGTGCACGCTCACGATGGAAGAGTTTCAGTGTTTTCGCAAACGTTGCCTCAAGTTCGACACGCTGGTGCGCCGTCTACGACCGACGGTGAAAATCGAACCGGGCTACGGAACAACGACGGAGCAGAAGCCGCAAGCCGCGTTCGTGCGGCACGATAAAACCGCGAAAAAAATGGCCGCTGCGTCGTCCGAGCTGCGGTCGTTTCATTGTCAGTATTGTCCCCGGAGCTTCAAGCAGCGAATGTATCTCGATCAGCATATGTGGAAGCACCGGGATAGAGTTGCTGCCGAAGCGGCCGGCAtacagcagcatcagcgcaCGCCGGCTGCGGTGAACGGTAACGGAAACGGTACCGTGACGATGATAAAGAAGGAACCGATCGCTGCGAGCAGGACGCCCACTCCGCAGCCTCCGGTCTCCGGCCAGACGGGCACGCAGGTGGATCGGCCGATCAGTTGCGAGTACTGTCCGCGGAAGTTTACGAGGCGAATGTACTACGTGCAGCATCTGCGCCGACACAAGCCGGAAGAGCGGTTGTTCCGCTGTCGGCACTGTACGCGCAGTTTCACGTCGCACATGAGGCGCGTCGGCCACGAGCGCAAAATACACGGCCACATAAGCAATCCCAAGACGGAGGAGAAGGACTCGTTCTCGTGTCCGAAGTGTGGGCGTGTGTTCAAACATCGGTCGTCGATGCGGATGCACCTGCTGAACCACGACGGGCAGCTACCGTACGGGTGTGACATCTGCAACTGTCGCTTCTACAGCGTCAGCCATCTGGGACTGCACAAAAAACGCTACCACGGTCCCAACGCGGCTCGATTGATGGCCAACGGTACGTCCATTCCGTGTCTGTACTGCACGCGATGGTTCCTGCGCGAGTGTGACCGGTCCAGCCACATCAAGCAGATGCATGCGGATATGCACGCGAGCAAGGCATCGGCGGCCGGCTTCAACGAGATGCTCAAGGACTGTCCACCGGCGGACCACGAGGGCATGACGGATCCCGAGATGCTGCCACCGAACGTACACGAACCGATGATGGTCATCAAGGAGGGGGAACCGGACAATGCGGGTGGTGCGAGTGGCGGTAGTGCAGGCGGTGCACTGCCGAATGCGACGATCACCGGCGATGTGGCGGGTTCGTTCCCATTCTACTGCTACTCCTGCGCCATGCCTTTCGACACCGAGGACATGTACTCGGAGCATCTGGACGATCAGCACCCGTTCGGGGGTGAACAGTTGATGGAACAGCTGCAGCCGTCGTCCTCCCCGGTCGAGCTGGACGGCAACTCTGCCAAGGTGTTCCTCTGCCCGTACTGCCCGAAAACGTTCACGCGCAAATGGAGCATGACGCAGCACATTCCGACGCATCTCGGCCGGAAGGGCTACCAGTGCGAGTACTGCCCGGCCATCTTCACCCGCAACGAGTACCTGCGGACGCACCGGCAGCGCAAACATCCGACACTGCCGGAAACGGGCTCGTACAAGTGCAGTTACTGCCCGCGGCTGTTCCACAAGGCGCGCTACAAGAAGGTGCACGAGCGGATCGCGCACATCAAGAAGGGGGACGTGCTGCCGGACGGGGACGATACGGAGGAGAGTGAGCTGGTGGCACTGACCGGGGCGCCCGGTGAGAAGATGgacgaaagcagcagcagcatcgcgttCGGGCCACCATCCCGCGCGTCGGACAGTTTCGATCAGACGTCGAACGATGCGCACAGCGTGTCCGGTTCTGGTCCGGTGCCCGACTACTCCGACCTCGAGGCGACGAATCGACTTGTGGTTGTGCTGGAACGTATGCCACCGGAACAGGTGGAAGAGTACCGGTGGCAGCTGGAGCTGTACGAGAACATGTCACCGGAGGAACTGATCGGCCAGTCATCGGCGGATGAACCATCTGAGGTAGACGAAGCTGCGGATGACACGCTCGAGTTGATCGATGCGCAAGACGACCACGGACAAGCAGCACCGGTGTTCAAGCGCAAGCGTAGCAAGTTTGGCATCACACTGCACCCGTGTCCCCACTGCTCGAAGATGTTCAAAACGCGTGGCGCTCTGCGGATGCACGCGCTGTACCACAGCGGCGAACTGCCGCACCGGTGCGACGAGTGTGGCGTGCAGTTTATGCGCTACAACCAGCTCGAGTATCACAAAACCCGCTACCATGGCGCCAACAGTGCGACGATGGCCGCACGCTACAGCTGCGATTACTGTCCGCGCATCTTCCTGCGGAAGCAGGACCGCACCACGCACCAGATGATGGTGCACGCGCGGGATCAGGCCGACGCGATCGACGCATCGCCGGGACCGACGCGGATGCACTCGAAGTCGAAACGCAAGGACTACGTGTGCCGGACGTGCGACCAGGAGTTCGATACGTACCGCATCTGCCAACGGCACATCTTCGTGTATCATCCCACCGTCGAGGGCGGTTCGGCGGTGGAGAGCAAACCGATGAAACTGTGCCACTGTAGCATCTGCAACGGGATCTACAAGAAGCGGGACGATTGGCACGATCACCTGAACAACCACCCGAGTGTGCGGCCCCATCACTGCGAGCAGTGCATCCGGCGGCGTCGCAAGGCATCGAGCCGGAAGCAGGTGCACCGCTGCTCGTACTGCCCGAAAGCGTTCGAGCACAAGCCGAACCTGGCGTCTCATCTGCGCATCcacaagcagcagctgcggttCCCGTGCAGCGAGTGTGGCGTCATGTACGACCGGTACCGGGACCTGTTGGCACACCAGAGCCGCTATCACTCGCAGGATCCCGCGGAGGCGGGAGCGACCCGAGAGCCGCTGCAGAAATGTAACTTCTGCCCGCGTGTCTTTACCCGGCTGCGTGACGTCAAGTACCATCAGGAGCAGGTGCACGCGGATCAAGAGATCCCGACGGAGCAAGCCACACCACCGGAGGAGGATAGTACTGGCCGCGAGCCGGATGCCAGGGATGataacgacgacaacgacgtcgaggacgacgagctgcCTAAGACGTTCGGGTTTGGGCCGGAAATGTTCCCGGAGACGGACCTGCAAATGCCAGAGGGCTCCGACCACAAACCCATCAAACCGGAACCTGAGccagaaccggaaccggaaccggaacctaTACCACagtaa
Protein Sequence: MEPEQEPEPVVDDDPVDVPNQNPESYCRFCFSENEVEPLFSANGTQASADLLDRIYDCIGIRLTKREYCPSGICWSCTLTMEEFQCFRKRCLKFDTLVRRLRPTVKIEPGYGTTTEQKPQAAFVRHDKTAKKMAAASSELRSFHCQYCPRSFKQRMYLDQHMWKHRDRVAAEAAGIQQHQRTPAAVNGNGNGTVTMIKKEPIAASRTPTPQPPVSGQTGTQVDRPISCEYCPRKFTRRMYYVQHLRRHKPEERLFRCRHCTRSFTSHMRRVGHERKIHGHISNPKTEEKDSFSCPKCGRVFKHRSSMRMHLLNHDGQLPYGCDICNCRFYSVSHLGLHKKRYHGPNAARLMANGTSIPCLYCTRWFLRECDRSSHIKQMHADMHASKASAAGFNEMLKDCPPADHEGMTDPEMLPPNVHEPMMVIKEGEPDNAGGASGGSAGGALPNATITGDVAGSFPFYCYSCAMPFDTEDMYSEHLDDQHPFGGEQLMEQLQPSSSPVELDGNSAKVFLCPYCPKTFTRKWSMTQHIPTHLGRKGYQCEYCPAIFTRNEYLRTHRQRKHPTLPETGSYKCSYCPRLFHKARYKKVHERIAHIKKGDVLPDGDDTEESELVALTGAPGEKMDESSSSIAFGPPSRASDSFDQTSNDAHSVSGSGPVPDYSDLEATNRLVVVLERMPPEQVEEYRWQLELYENMSPEELIGQSSADEPSEVDEAADDTLELIDAQDDHGQAAPVFKRKRSKFGITLHPCPHCSKMFKTRGALRMHALYHSGELPHRCDECGVQFMRYNQLEYHKTRYHGANSATMAARYSCDYCPRIFLRKQDRTTHQMMVHARDQADAIDASPGPTRMHSKSKRKDYVCRTCDQEFDTYRICQRHIFVYHPTVEGGSAVESKPMKLCHCSICNGIYKKRDDWHDHLNNHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCSECGVMYDRYRDLLAHQSRYHSQDPAEAGATREPLQKCNFCPRVFTRLRDVKYHQEQVHADQEIPTEQATPPEEDSTGREPDARDDNDDNDVEDDELPKTFGFGPEMFPETDLQMPEGSDHKPIKPEPEPEPEPEPEPIPQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00106537;
90% Identity: -
80% Identity: -