Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB672824.1:224647-227385[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0016 0.09 12.8 4.7 1 23 40 62 40 62 0.90

2 9 1.6e-06 8.9e-05 22.2 0.5 1 23 68 93 68 93 0.95

3 9 0.0029 0.16 11.9 0.8 3 23 106 129 105 129 0.91

4 9 7.7e-07 4.3e-05 23.2 1.2 1 23 135 157 135 157 0.96

5 9 0.00054 0.03 14.2 2.6 1 21 163 183 163 184 0.94

6 9 1.8e-05 0.001 18.9 0.3 2 23 189 211 188 211 0.96

7 9 0.00015 0.0083 16.0 4.7 1 23 215 237 215 237 0.97

8 9 0.00048 0.027 14.4 2.2 1 23 249 274 249 274 0.98

9 9 0.00021 0.012 15.5 0.3 1 23 282 306 282 306 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0016	0.09	12.8	4.7	1	23	40	62	40	62	0.90
2	9	1.6e-06	8.9e-05	22.2	0.5	1	23	68	93	68	93	0.95
3	9	0.0029	0.16	11.9	0.8	3	23	106	129	105	129	0.91
4	9	7.7e-07	4.3e-05	23.2	1.2	1	23	135	157	135	157	0.96
5	9	0.00054	0.03	14.2	2.6	1	21	163	183	163	184	0.94
6	9	1.8e-05	0.001	18.9	0.3	2	23	189	211	188	211	0.96
7	9	0.00015	0.0083	16.0	4.7	1	23	215	237	215	237	0.97
8	9	0.00048	0.027	14.4	2.2	1	23	249	274	249	274	0.98
9	9	0.00021	0.012	15.5	0.3	1	23	282	306	282	306	0.97

Sequence Information

Coding Sequence: ATGGCACCCGGCGCGGAGCAAGCGGCCGTGAGCGCGATGGCTGCCATAGCGTCCGACATCTTAACCCCGCCATCAACTCCGCCGACCAAGCGcgccgacagcagcagcagccatcgcTACCGGTGCGAACACTGCGGTCAAACGTTCAAGCGCCAGGACGCGCACGATCGGCACCTTTTCCAGCACACCGGTGTGCACGAGTACCAGTGTCTCGAGGCGGGCTGCGGCAAGGCGTACACAAACCGTTCCCACCTGGCGCGTCACGTCCGCGCGAAGCATCTCGAGCGTCCGGCCGAGCGGGAGCCGCCCCGTGCGTGCAAGCATCCCGGCTGCGGGAAGATGTTCGCGAGCGAGCAGAAGATGATGCGCCACTTCCGCGCTCTGCACCTGCACGGCAGGAGCTACAAGTGCGACGACTGCGGGGAGCAGTTCACGCGCAAGGTGCAGCTGCGCTGGCACCGGTACCAGCACACCGGCCAGTACCCGCATCGCTGCACGGCCTGCGGCGAGAACTTCACCAACCTGAAGGCACTGCAGCGGCACCGGTGCCGGGAGCGGGCCGTCCAGTGTACCCGGTGCGACCGGGCGTTCGCGCGCTGGTCCGAGATGGTGACGCACCGCCGGCTCGAGCATCCGGCCGTGCACCGGTGCGAGCAGTGCGGGAAGCAGTTCCACACGCGCTCCGCGATGAAGCAGCACGCCCGGCTGCACCGGACGGGCGAGGCGGAGGGCGAGCGCGACGTCTACCAGTGCCCGCACGAAGGCTGCCCCCGGTTCTACGAGCACGAGCGCAACCTGTACGCGCACGTACGCTCGAAGCACGAGGGCCGGAAGCGCGAACAGCACGTCTGCCCGGTGGCGGACTGCGGCCGGGTGCTGGCCACCCGCCAGAAGCTCAACCAGCACCGGAAGCTGCATCTGCGCGCGTCCAAAGCGCGGAAGGTGCCTGCCCCGGCACGGGTCGCCGTGCCGAAGGAGCTACCGGCGCCGGCGCCGGCCCCGGTGGACGTGACGACCGACTCGGAGGTCGAGTCCGGCATGCCGGCCGCACCGGAACTGCTCTCCTGCAACCTGCAGCGTCTGTGCGCCGAGCTCGATGCGATGCGCGCCGAAACCGGCGAGCTAGCCGTTTAG
Protein Sequence: MAPGAEQAAVSAMAAIASDILTPPSTPPTKRADSSSSHRYRCEHCGQTFKRQDAHDRHLFQHTGVHEYQCLEAGCGKAYTNRSHLARHVRAKHLERPAEREPPRACKHPGCGKMFASEQKMMRHFRALHLHGRSYKCDDCGEQFTRKVQLRWHRYQHTGQYPHRCTACGENFTNLKALQRHRCRERAVQCTRCDRAFARWSEMVTHRRLEHPAVHRCEQCGKQFHTRSAMKQHARLHRTGEAEGERDVYQCPHEGCPRFYEHERNLYAHVRSKHEGRKREQHVCPVADCGRVLATRQKLNQHRKLHLRASKARKVPAPARVAVPKELPAPAPAPVDVTTDSEVESGMPAAPELLSCNLQRLCAELDAMRAETGELAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -