Basic Information

Insect: Anopheles dirus
Gene Symbol: prg
Assembly: GCA_000349145.1
Location: KB673423.1:3392662-3394667[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.086 4.8 7.3 0.4 1 23 237 260 237 260 0.81

2 10 0.65 36 4.6 3.6 3 23 268 289 266 289 0.95

3 10 0.00066 0.037 14.0 1.3 1 23 295 317 295 317 0.96

4 10 3e-09 1.7e-07 30.8 1.5 1 23 323 345 323 345 0.98

5 10 2.7e-06 0.00015 21.5 1.0 1 23 351 373 351 373 0.95

6 10 0.0041 0.23 11.5 0.4 1 21 380 400 380 401 0.93

7 10 0.00017 0.0094 15.8 1.1 1 23 482 504 482 504 0.98

8 10 0.0015 0.086 12.8 6.6 1 23 512 534 512 534 0.99

9 10 3e-05 0.0017 18.2 1.6 1 23 540 562 540 562 0.97

10 10 4.9e-05 0.0028 17.5 0.0 1 23 568 590 568 590 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.086	4.8	7.3	0.4	1	23	237	260	237	260	0.81
2	10	0.65	36	4.6	3.6	3	23	268	289	266	289	0.95
3	10	0.00066	0.037	14.0	1.3	1	23	295	317	295	317	0.96
4	10	3e-09	1.7e-07	30.8	1.5	1	23	323	345	323	345	0.98
5	10	2.7e-06	0.00015	21.5	1.0	1	23	351	373	351	373	0.95
6	10	0.0041	0.23	11.5	0.4	1	21	380	400	380	401	0.93
7	10	0.00017	0.0094	15.8	1.1	1	23	482	504	482	504	0.98
8	10	0.0015	0.086	12.8	6.6	1	23	512	534	512	534	0.99
9	10	3e-05	0.0017	18.2	1.6	1	23	540	562	540	562	0.97
10	10	4.9e-05	0.0028	17.5	0.0	1	23	568	590	568	590	0.98

Sequence Information

Coding Sequence: ATGAACATTGCAAATGGAACCGTCCCCGCGGCGGAACGACAACTGTGCCGGCTTTGTCTGGGCCAGGACGGGCAGCTGATGGCTATTTTCGGTGTGCACGAGGCGGCCGTGACCCACGCGGAAACGCTATCCGCACGGATACGGAACTGCTTGCAGCTGGAGGTAACGCAAATCGATAGTCTCCCGAAGTGGATATGCAAGCTGTGTTTGGAGAAGATTGATGATTTTACAAACTTCCGGGAGCGATGCAAACATAACGAACAAAAGTTGTTGCTAGGCGACGGAGATTCGCACATGAAGGATGATCATATTGCGAACGATGCAGCAGATCAAGAGCAGACGGATTAcgatgacgaggacgaggaggaaatggaaatgattgTGATCGATCCGACGCGAGACTACGAAAGCTCGGGCGATGAAAGTCTCCCGGCGGAGGCTTATGTGGAGAAGAATGGACTGGCAAACACACAGCCTGAACAACATCCCGCCGCCGAGGAGGACGATCAGCAGGATGGTTCAGAAGCGGAGGATggagaggaggaagaggaggaagacgacgaagaagaTCTTAAATGTGATACGATACCGGCGGAAGCACGAAACGGATTACCGCATACCGGcagtgatggtggtggtagaatGAGCAATGCCACcacaaccaacaccaccatcaccaccacgactACCCTGCagaaaacgatcgtttacACGTGCAAGTACTGTGATGTGGCGTTCGCGGCGGCGTCCGCCTGCCAGCTGCACGAAATGCAGGACCACGACCTGCTGGCCCCGTACGGGTGTCTCTACTGCCACTACAAAACCTCCATCCGGACGTGTCTGATCACGCACATACGCGACCAGCACAGCATCACGCGCCCTTACATTTGCGTTCAGTGCAATAAGGGCTTTCTGCGCCGGTCCGATCTCAAGAAGCACACATTCGTGCATACGGGCGTGCGGCCGTACGCGTGCGACCAGTGCGGAAAGAGTTTTTCGCGCAACACGAATCTCAAGAAGCACATGCTAACGCACTCGGGGCTGAAGCCGCATGCGTGCGAGAGCTGCGACCGATCGTTCTCCAGCAAGGCGGACCTGCTACGGCACATGACGGTTCATAACGAGCAGTTGCGGCAGCATCCATGCGTACGGTGCGGAACGGTGTACACGCAGAAGGACAAGCTGTACGAACACGAGCGTTACTGTATGGGCCGGCATCCTAATTCGACGGTTGGGTTTGGCGGTATTTCCTTTGCTGATTTGAAGCAGGAGGCACCATTCGTGGATAATCTAACGGCACCGATCGCGCCGCCTCCCCCGCAGATGTGTACTCCGGCGGAGGAAGCGATCAAAATTGAACCACCCGTCATCGAACCACCGCCAAGTTATGCGCCCGCAGCATCACAACCGATGATTCCACAGACCCCCGCATCCAGCAAGATCTACGACTGCTCGAAATGCCCCAAGCGTTTCCTCAGTAAGATTAGCCTTCGGGCGCATCAGAGCACTCACTCGCCGGAAGAGTCGCGCAAGTACGAATGTCCGCACTGCAAAAAACACTTGTCCGGCAAGCGCGAGTTCGAGCATCACCTCCAGACGCACATGAGCATGAAACCATTCGCGTGTGCCACGTGCGGTAAGCGATTCTCTGCCAAGGATAAACTGCACCGACACGAGCGCGTGCACCAGCAGGATCGACACTTCTCCTGTCCGAACTGTGCGGCCAAGTTCGTGCGGAAGGATGCGCTAGAGGCGCACCTTCAGATTCACTGCAACCCGAATGCGGTCCCACCGCCACTCATCGGGACCGCGGGATTGTTTGCTTCAATCGGACACGGTGGGGCTGGTGCTGAGATTCCACAACAACATTCCCTGCTTTATTCGATGATCGGGGCAAATGATGGAGCGGCCGGGATCGATCCGTCAATTCGAATGTGA
Protein Sequence: MNIANGTVPAAERQLCRLCLGQDGQLMAIFGVHEAAVTHAETLSARIRNCLQLEVTQIDSLPKWICKLCLEKIDDFTNFRERCKHNEQKLLLGDGDSHMKDDHIANDAADQEQTDYDDEDEEEMEMIVIDPTRDYESSGDESLPAEAYVEKNGLANTQPEQHPAAEEDDQQDGSEAEDGEEEEEEDDEEDLKCDTIPAEARNGLPHTGSDGGGRMSNATTTNTTITTTTTLQKTIVYTCKYCDVAFAAASACQLHEMQDHDLLAPYGCLYCHYKTSIRTCLITHIRDQHSITRPYICVQCNKGFLRRSDLKKHTFVHTGVRPYACDQCGKSFSRNTNLKKHMLTHSGLKPHACESCDRSFSSKADLLRHMTVHNEQLRQHPCVRCGTVYTQKDKLYEHERYCMGRHPNSTVGFGGISFADLKQEAPFVDNLTAPIAPPPPQMCTPAEEAIKIEPPVIEPPPSYAPAASQPMIPQTPASSKIYDCSKCPKRFLSKISLRAHQSTHSPEESRKYECPHCKKHLSGKREFEHHLQTHMSMKPFACATCGKRFSAKDKLHRHERVHQQDRHFSCPNCAAKFVRKDALEAHLQIHCNPNAVPPPLIGTAGLFASIGHGGAGAEIPQQHSLLYSMIGANDGAAGIDPSIRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -