Adir003550.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles dirus
Gene Symbol
-
Assembly
GCA_000349145.1
Location
KB673534.1:5052476-5058519[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 8.9e-06 0.0005 19.9 2.5 1 23 284 306 284 306 0.97
2 9 3.7e-08 2.1e-06 27.4 1.2 1 23 312 334 312 334 0.98
3 9 2e-05 0.0011 18.8 1.4 1 23 340 362 340 362 0.99
4 9 0.013 0.75 9.9 0.9 1 23 368 391 368 391 0.95
5 9 0.0018 0.099 12.6 1.5 1 23 589 611 589 611 0.98
6 9 0.021 1.2 9.2 0.6 2 21 744 763 744 765 0.94
7 9 9.4e-08 5.2e-06 26.1 4.3 1 23 782 804 782 804 0.99
8 9 5.9e-05 0.0033 17.3 1.2 1 23 810 832 810 832 0.98
9 9 0.0015 0.082 12.9 0.4 1 22 838 859 838 859 0.96

Sequence Information

Coding Sequence
ATGGTGAAGGAAATGCCGTCGAGCACGGTGGTGAACCGCGACGAGGAATGTCTCAAGAAGTCCTTAATGGAGGTTGTGAAGAGCGATTCGAGCAACTTATGCCGGTTATGTTTGTCAAAGGAGCAAAAGCTCACACGCGCCTTCACAGACGAGAGAGGGATCGATGATGCGCTGCTGAAGAAAATCTTCGACTGTACTACAGTGAAGgtgaaattaaaaaccattttCCCGTCCGCCATTTGTGCGGTGTGTGACTTGAAGCTGAATGAATTCTACAAGTTCCGTGAGAAATGCATCGAAAACGACACCTTCCTGCACAGTTTGCTGGACGAACGGCTGGCGGTGCCGGAGGTCGATCAGTCAGTTCCGACCGTCAACGATAGgcgaccgaaccgagcgtCCGAGTGTGGTGGAAGTGGCTACGGGAAGGAGCTACAGACTGAGCAGCAGGCGGCAACATCGACCACATCGATCACGGAGACTCAGAAGGAcggtagcagtagcagcaccagtagcagcagtgaGATGATGGCCATAGCACTGAACCAGCTGACGTCCTTCGGGTTGCGACCGTTGCAGGAGTTGATGCTTGAAGCGAACGTGGGAAACGATTCGGtggtagctgctgctgctactggaaCGCTCCTTCCAACCGGGGGTGGAAATATCGTTTCGTCTTCCTCAGCACCAACGCAACAACACGACGGACCGACACCGCGACACCTGCCCGCGATTAAGCTGGTCGAGCAGAAGAAGCGACAGATGGAGCAGGAGCGTACGTTTGCGATGGCGGCACTGGAGATGGCCGGCCTGCAGACATTACGGACCAGTACCGAGGCCAGCGGAAAGTTCGAGTGCGCCATATGCCATCGAATGTTCCGCAACGCGTACACCCTCCGGCGGCACACGAATCTGCACACGGAAACGAATCTGTTCCCGTGCGAGTACTGTGGCAAAAAGTTTAACGATCGTTCCAACTGGAAGATCCACCAGCGGACGCACACCGGCGACAACCTGTACACCTGTCTCGTCTGTCTGAAGACGTTCATCTCGCCCTCCACACTGAAGTACCATCGGCGGTCGCACCGTCGGCTCGAATCGTTCGACTGTCGGCTCTGCCCGTGCACGTTCGGTAGCTACGATCTGCTGGAGGAACACGCGCGCAACACGCACCAGGACATGCGCGACTTCCAGCCCGCCGACGAGCCGATGATAGACGCGGCTAGCTTCGTCAAGATCGAGCTGGAAGACGAGGGTGAACTGTCCAGTTCGACGGCGGTTGGCGATGTGTCCACCACGCAGCAGCATCCACCGGCGAATGAtgcggacgacgaggaggaccGGGAGCAGCGACGAACGGTCGTGGATAGCAGTGGCGGCGTGGACGAGCTGCAAATGGCGGAGCTGTACCGAACTCAGCAGCAAATGCTGGAGCTGTTGGAGAAACACCTTCAAGCGGGAGTGGGAGGAGTTACGGGAGAGTGTAAAGTAGGCGTTGGACAGGCACTCGGTGAAGAGCACGATGAGGGCATAAAGCGGGAGATGTTGGAGGAGCAACATCGGCaacagctgcaacagcagcaacacgagCAGGATATCGCAGTGAAGGAGGAACCGTTCGACGAATCGATGGAACTAGATCCAAGTGAACTGTTGCAGCAGGCAATGGAGGAAGCGGCGGATGAAGGTGGCGAAGCTGACGGTGGTGAAGACAAGCAGGCATCGTCTTCGAGTGCGTCGTCATCACCCTCGACGGTGATACTGTTTCGATGTGACTACTGCatgaaaatattccatttcCTAGATGAGCTGAACGCACACATGCTCCTGCACAACGGAGCCAAAGGTGTCGGCACAGGTGGTGGAGCGATTATGCTCGGATCCGGGGCAGCTACTGCAGATGGACCCACCCTAACGAAATCAATGCCATTGCTGTCGTTGATGCGACCAGCTGCCGCAGCCACCGCTGCTAGTTCTGGTCCCATTCCTCTGCTGGTCAACGGTACCACGATGGGAGCGGACGTTATAGAcagtgggggtggtggtggcggtgtcgtAACATCCGCCTATTCTCACGAACTACCTTCCCTGCACAATGTCGCCGACGAAAGCGATGAAGGGGAAACGACCGTAGGTCGAGTGCCGGTTGTCGTTACCGCGTCACCGGAGGTTGGCTCAGAAGTGGCactctcctcctccacctcgtTGAACCGGACCGCTGCCTTCCGGAGGTGCGAAATCTGTGCCATCTCCTTCGAGGACTCGGTAACGCTCGACAAGCATATGCTGTGCCATTTCGAGCGCAAGGAGGCGATTGCGTTCGTGCCGCAAACGGACCGCCCTTTTCAGTGCACCGAGTGCCACAAGAGCTTCAAACGGAAGGACTATCTGCTGATACACATCCGCACGCACACTGGTGAGCGGCGGTACAAGTGCGACCTCTGCTCGAGCGCGTTCGTGCATCCGTCGAACCTGATCACGCATCGGAAGCTACACTCGAGCGAGCGTCCGTACCAGTGCACACTGTGCGGTTCCACTTTTAAGCTGTACGCTGGGCTCAAGATTCATCGGAGGCGCTGCGAACAGAAGCTGCCGAAGAGCTGGCCAGAAGGACTGCTGGCAGGTGTTGCTACTGGTGCTGGCAATAGTATGCACGATctgcacgacgacggcggtaCTCAACTAGCGAACTGCAATGTGTCCTATCCATTTTAG
Protein Sequence
MVKEMPSSTVVNRDEECLKKSLMEVVKSDSSNLCRLCLSKEQKLTRAFTDERGIDDALLKKIFDCTTVKVKLKTIFPSAICAVCDLKLNEFYKFREKCIENDTFLHSLLDERLAVPEVDQSVPTVNDRRPNRASECGGSGYGKELQTEQQAATSTTSITETQKDGSSSSTSSSSEMMAIALNQLTSFGLRPLQELMLEANVGNDSVVAAAATGTLLPTGGGNIVSSSSAPTQQHDGPTPRHLPAIKLVEQKKRQMEQERTFAMAALEMAGLQTLRTSTEASGKFECAICHRMFRNAYTLRRHTNLHTETNLFPCEYCGKKFNDRSNWKIHQRTHTGDNLYTCLVCLKTFISPSTLKYHRRSHRRLESFDCRLCPCTFGSYDLLEEHARNTHQDMRDFQPADEPMIDAASFVKIELEDEGELSSSTAVGDVSTTQQHPPANDADDEEDREQRRTVVDSSGGVDELQMAELYRTQQQMLELLEKHLQAGVGGVTGECKVGVGQALGEEHDEGIKREMLEEQHRQQLQQQQHEQDIAVKEEPFDESMELDPSELLQQAMEEAADEGGEADGGEDKQASSSSASSSPSTVILFRCDYCMKIFHFLDELNAHMLLHNGAKGVGTGGGAIMLGSGAATADGPTLTKSMPLLSLMRPAAAATAASSGPIPLLVNGTTMGADVIDSGGGGGGVVTSAYSHELPSLHNVADESDEGETTVGRVPVVVTASPEVGSEVALSSSTSLNRTAAFRRCEICAISFEDSVTLDKHMLCHFERKEAIAFVPQTDRPFQCTECHKSFKRKDYLLIHIRTHTGERRYKCDLCSSAFVHPSNLITHRKLHSSERPYQCTLCGSTFKLYAGLKIHRRRCEQKLPKSWPEGLLAGVATGAGNSMHDLHDDGGTQLANCNVSYPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-