Adir009239.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- -
- Assembly
- GCA_000349145.1
- Location
- KB673201.1:5076823-5080369[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 6.4e-05 0.0036 17.2 2.6 1 23 19 41 19 41 0.97 2 13 0.00014 0.0081 16.0 0.3 3 23 49 69 48 69 0.98 3 13 2.6e-06 0.00014 21.6 0.7 1 23 75 97 75 97 0.96 4 13 0.12 6.9 6.8 0.7 1 21 103 123 103 124 0.94 5 13 0.00047 0.026 14.4 1.0 1 23 427 450 427 450 0.95 6 13 0.0011 0.064 13.2 0.3 1 20 474 493 474 496 0.93 7 13 0.78 44 4.3 1.7 1 23 504 527 504 527 0.94 8 13 0.00026 0.014 15.3 2.0 2 23 532 554 531 554 0.95 9 13 0.11 6.2 7.0 0.1 1 21 565 585 565 586 0.88 10 13 4.2e-05 0.0024 17.7 2.5 1 23 594 616 594 616 0.98 11 13 0.00011 0.006 16.4 0.7 1 23 622 644 622 644 0.98 12 13 6.6e-05 0.0037 17.1 0.9 1 23 650 672 650 672 0.98 13 13 0.035 2 8.5 3.6 1 23 678 700 678 701 0.95
Sequence Information
- Coding Sequence
- ATGGATATTAAAGTGACAATCGAACCGCCCAGTCGTGGGGCCCTGGAAAAACCTTTCCAGTGCGATATCTGCCATCGGTTTTACGCGTCGAAAGCATCCCTAAAGACCCATCGGCTGCTGCACACTTCGGAAAAGAAAGAGCTGTGCGATTTTTGTGGTGCTGCTTTTCAAACACGCGGCCAGCTGAAAATACACAGACGCGTGCATACGGGCGAGAAACCGTACCAATGTGAGGAATGTGATAAATCGTTTTCGTATCGCGAAAGTCTGATAACCCACTCGACCGTGCACACAAACATCAAACCGTTCGTGTGCACCGTTTGCAGCGCGCGATTTTCGTGCATTGGAAATCTGCTCAAGCATCGCAAAGTGCGGCGGAATAAATGTGGGGTGGAAAACGTACCCATTAAACCGTCCGAATCGCGGCCCAACAAAAAGACTATGCCCAGCTTGACCGATCGTTCCAGTACATGGGAACGGAAAGAGCGCAAGACAAAATCGTTCATTACGGTCCTTAATTCAGTTGAGATACTGAACTGCAACGATGGATATTCAGAGGAACCAGATGATTCACCAGCAAACGTCGCGGAAAACGTAGAAGAATACGATCATTTGAGCGTAGGAATACACGAACCCTCTGCGGATGCTTCTTCGTTCGATGGAGAAAGTGTTGTTTCCGATACGGACGTTGGCAAATCCGTGATGCTTGATGCGAGTTTTCTTAACGCCGCAAGCTCTATTGATAGCAGCGAAGATGATACTAACGACCAGCAACAGAAAGAAGAGCACACCATCGACTGTTCGGATAATGAATTTAGCGAACGCGCTGACGCCACATTGGATATCCCTGTCACGAACGATGAAGCGAAAGATAAAACGTTCGTTTATACGATAAGTTTTACAGACGCATCGGACCCGACATcgtccatcagcagcagtagcaaagCGACTGAGTTGTACAAAATAGTAGCATCGAACGAGAAGGGCTTTAAAAACCACCCTGAACCATCAGAAGCACCTGAACTAAACTCGATCGATGGTGATGAATCGTGGGAACATTCCGAAATCGCTGAAGCTGAAGCAAATGAGATAACGCCCAGGTCCAGGTTGGCTGTGCGAACGAGATcacggaggaaaaaacaattgGAGCGAACTGTTGAATCAGCTTCGATTGACCCAGTTGCGGTACCAGATGAAGAGTTGCTTAAGCAGAACGAGAAGAGATTGCAGCAGCAATTAGGGACCCTGGGCGAATTATCAGAGCCACGTGATGATTGCTACCGCTGCAAGCTGTGTCCGCAACAGTACACCACGCAGTACCTGATGGCACGACACCTGGAACAGACGCACGGCGTACCACTAGACTGTGCCCGAGAAAAGCTGCAGTACGTGAAGAACACCACCAAACGAGAGACCAAATATCGCTGCCAGTACTGCGATCAGTCGTACGTGAATGCGATCCGGCTGGCAAAGCACATTCCGAAACACGGCCCAGAGGGACGGCTGCGCTACAAGTGTCCCTGCTGCGAGCAGCACTTCGAGACGGTGGCACAAGCACAGCAGCACGCTCGCGACGAGCACCGCAACCGTTTGGAGTGTGACCGGTGCCGGAAGCCGTTCACGAAACCCCAGTGCCTGCAGCGGCACGTCCGGTACGCGCACGGCACTGCGAAAGCGTCCCGCAAACCGCGCCACATGTGTGCCCGGTGCGGGAAAAGCTTCCTCTCACTAACCGCCCTGTCCGATCACGAGCGGGCCGACTGTGGCAGTGCGCCCATCTATCGGTGCGGCACGTGCGGCAAGCACTACTCCAGCTACAGCGCGCTGAAGATGCACCGGACGGTCCATGACGGGGCGCGCCCGTTCGAGTGTAGCTTCTGCGCGAAACCGTTCCGCACCAAGGGCCAGGTGAAGGTGCACGAGCGGTCGCACACCGGGGAGAGACCGTTCCGGTGTGAGGTCTGTGCGAAGTCGTTCCCGTACCGGGAGTCACTGCTGACGCATCGCACCACGCATACGGGCGTGATGCGGTTCGCGTGTGCCGACTGCGATGGGAAGTTCTCGTGCATCACCAATTTACAGTCCCACCGACGAACGCACCACTCCGGTGAGGCGGAATCCGCGATCGAGCGCGACACGATAGGGTGCAAGAAATAA
- Protein Sequence
- MDIKVTIEPPSRGALEKPFQCDICHRFYASKASLKTHRLLHTSEKKELCDFCGAAFQTRGQLKIHRRVHTGEKPYQCEECDKSFSYRESLITHSTVHTNIKPFVCTVCSARFSCIGNLLKHRKVRRNKCGVENVPIKPSESRPNKKTMPSLTDRSSTWERKERKTKSFITVLNSVEILNCNDGYSEEPDDSPANVAENVEEYDHLSVGIHEPSADASSFDGESVVSDTDVGKSVMLDASFLNAASSIDSSEDDTNDQQQKEEHTIDCSDNEFSERADATLDIPVTNDEAKDKTFVYTISFTDASDPTSSISSSSKATELYKIVASNEKGFKNHPEPSEAPELNSIDGDESWEHSEIAEAEANEITPRSRLAVRTRSRRKKQLERTVESASIDPVAVPDEELLKQNEKRLQQQLGTLGELSEPRDDCYRCKLCPQQYTTQYLMARHLEQTHGVPLDCAREKLQYVKNTTKRETKYRCQYCDQSYVNAIRLAKHIPKHGPEGRLRYKCPCCEQHFETVAQAQQHARDEHRNRLECDRCRKPFTKPQCLQRHVRYAHGTAKASRKPRHMCARCGKSFLSLTALSDHERADCGSAPIYRCGTCGKHYSSYSALKMHRTVHDGARPFECSFCAKPFRTKGQVKVHERSHTGERPFRCEVCAKSFPYRESLLTHRTTHTGVMRFACADCDGKFSCITNLQSHRRTHHSGEAESAIERDTIGCKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -