Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB673090.1:9559407-9565311[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5.2e-05 0.0029 17.4 1.1 1 23 246 268 246 268 0.97

2 15 0.0083 0.47 10.5 2.2 1 23 274 296 274 296 0.97

3 15 8.5e-05 0.0048 16.8 0.7 1 23 455 477 455 478 0.93

4 15 1.7 93 3.3 0.1 3 23 491 512 489 512 0.94

5 15 0.016 0.88 9.6 1.1 1 23 537 560 537 560 0.95

6 15 0.26 15 5.8 0.0 3 23 650 670 648 670 0.96

7 15 0.014 0.81 9.8 1.6 1 23 680 703 680 703 0.94

8 15 0.0025 0.14 12.1 0.8 2 19 711 728 710 729 0.95

9 15 0.00036 0.02 14.8 8.0 1 23 738 760 738 760 0.97

10 15 0.023 1.3 9.1 0.8 2 23 766 787 765 787 0.97

11 15 1.1e-06 6.4e-05 22.7 0.4 1 23 793 815 793 815 0.98

12 15 0.00083 0.046 13.7 0.2 1 23 821 843 821 843 0.97

13 15 2.2e-05 0.0012 18.6 0.1 1 23 849 871 849 872 0.95

14 15 0.99 55 4.0 0.1 1 23 887 913 887 913 0.92

15 15 0.014 0.8 9.8 0.3 1 20 1413 1432 1413 1435 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5.2e-05	0.0029	17.4	1.1	1	23	246	268	246	268	0.97
2	15	0.0083	0.47	10.5	2.2	1	23	274	296	274	296	0.97
3	15	8.5e-05	0.0048	16.8	0.7	1	23	455	477	455	478	0.93
4	15	1.7	93	3.3	0.1	3	23	491	512	489	512	0.94
5	15	0.016	0.88	9.6	1.1	1	23	537	560	537	560	0.95
6	15	0.26	15	5.8	0.0	3	23	650	670	648	670	0.96
7	15	0.014	0.81	9.8	1.6	1	23	680	703	680	703	0.94
8	15	0.0025	0.14	12.1	0.8	2	19	711	728	710	729	0.95
9	15	0.00036	0.02	14.8	8.0	1	23	738	760	738	760	0.97
10	15	0.023	1.3	9.1	0.8	2	23	766	787	765	787	0.97
11	15	1.1e-06	6.4e-05	22.7	0.4	1	23	793	815	793	815	0.98
12	15	0.00083	0.046	13.7	0.2	1	23	821	843	821	843	0.97
13	15	2.2e-05	0.0012	18.6	0.1	1	23	849	871	849	872	0.95
14	15	0.99	55	4.0	0.1	1	23	887	913	887	913	0.92
15	15	0.014	0.8	9.8	0.3	1	20	1413	1432	1413	1435	0.94

Sequence Information

Coding Sequence: ATGGATCACAATCCATTTCCCCTGTGGCAAGTGTCAGCGACCGATCCGGCAGCGagaggcagcggcagcagcacggtcaACAACACTGCAAGCATTTCCACTCTAAACTACGTTCCTAACATGCGGGCAAAGATGAAGATCGTAAACATAAGCACCCAAATGACGCGTGCCAACGAATCCGGCAACTTGTACGGTGCAACTACTGCTACCTATTTGCCGGCGGTGACCGAACGACAGCAGCTGGTTCATCATCAGCCTCGGCGAATGGCGACAATCCCGCAAAATGCGAACACCATGCTGAATGAGTCCATTCTGCTCCAAACGCACGACGGTCGGGAATATCTCGTAGACGAGAGTTCGATTCAAAACATCGACCAGATACCGCCGGAGAACCTAATCTACAtgacaacaaccaccaccacgcccaCCACGGAGGAAGGTGTTCTTGCCGATCATCTCGCGATGAACGGCGGTGATGATTTCGAGGTACAAAGTGGTGGTCAGCCGCTGGACCATCAGCAGGGTGAATCCGTGCCGGATCTGCAACAATCCGCGACAACAACGTACGCGGAAGAGTGTGAAGTGACGGAGGAGATAATTACGGACGATTGGGTGCAGTCGCAGGGAGAGGAGTGTGTGCAGGTGACGGTCGATCAGCTCGGTGCGAGTGCGATCGTGGTGGAGGACGACATCGCGGTGCCGCTCGATCAGGACCAGTACACGTTGTCGCGTCCGTACCCATGTGACTTCTGCAGCCGGCGGTTCCGGAAGAAGGCTAGTCTGCAGAATCATCTGATGGCGCACTCGAACGATCGGCCGCATGTGTGCAATTTGTGCGGTGCCCAGTACGGTCGACGGTGCGATCTTATAAACCATCTGAAGCAGCATGCGTACGCCGTGACTGAACAGGACGAGCTATCCGTTCGGGGGGCAGGTGGAGAACAGGATGTAGACTACGAATTGCCCGAACTAATACCACGGCCGGATTaccaccaacatcatcaacagctCAAGAAGCAACGCGCAAGACAGTCGAGCGACGACGAAGACATGTACATACAGAACGCGATGGTGAACTACAACTCGCAGCCTCCGATGCAGCTTATTTCCACGACAAACTATGGATCATCGTCTTCCTACACGAATGGCGACTCTCTCGAGCAGATGGTGGACGACGGTGGGACGAAGGTAATACAGCAACCGGAaccaccaccattaccacCCATGCCTGGTACACCCGGACGCAAAAAGGTAGCGTCCAGAACCGGAGGctacataaaaaaggaaccgCTCGACACCGCGGAAGAACCGGTCACGTCCGAACCCACCCAGTTCCCGGTGACGACGGACGGCCGTAAGACGTTCCTGTGCCAGGAGTGTGGCATCTCGTTCGCACGGTATAAAGCGCTTGTGGCACATACGCgaaatcaccaccaccaccagcagcaacaacagcagcaccagtacgGGTGCGATATTTGCGGTGCACTGTTCTGGGAGCAGACGCTGCTGCAGGATCATGTACGGCATGCACACGGCATGACGACACCGGAGAAGAAATTCGTCCCACCCTCACCGGGGCCGGCGTCGCCACCGGTGAAGAAGCATTTTAATTGTGATAGTTGCAGTGCGATCTTCTTCCAGCTGGACCATCTGCAGAGTCATCTGCAGCAGGCGCACGGTTTGAAGCGTGCCATCGCGTCCAGTGGGAaaccgcagcggcagcaggagctCCTGCTAATGTCAACAAGAGGGCACGCGGATGACGAGGAACGGGAAGAGGAAGAATCAACCGATCAGGACGAGGGGGAGGAAGACTTCGAGGATCTCGACTACACGTACGAGGCGTATGAGGAAAGCCGTACCACCGACGGGCCTGACTCGAGTCAGGCATCGGAAGTTACGGGATCGCAGGAGCAACCCCAGCAGCAGGAGTTCCCCATGGCCTGTCGCGACTGCAACGAAATGGTCGCAAGCGCAATCGATCTGCTCGAGCACGTGGAAATGCACGGCAACTCGGCCCGGTACGAATCGCCGCACGAGTGTCAGCTGTGCGGGGAAAAGTTCTTCGACGAGTCGTTCATCAAGCGGCACGTACAGGAGCGCCACCGAGCCGAGCTAACCGACACGTCCTGTGCGATCTGCGGCAAGCGGTGCAAAAGTCAGACCACGCTGATCAAGCACGCCTGGGATCATTCCCGGGACCGGGCGCACTCGTGCTCGAAGTGCGGCAAAACGTTCCACCACCAGGCGCGCCTCAAGCGCCACATGGACTCACACCGCAGCAAGGCGGTCCGATGCGAGATTTGTTCGCAGGAGTTCCCGGACGGGCGCACCCTGATGAACCACCGCCACTCGCACTCGAAATCGAACGAGTACCCGTGCACGGAGTGCGGCAAAACGTTCGGATCGCGTTCGTCACAGCAGATCCACATGCGCATCCACACCGGCGAACGGCCGTACGCGTGTCGGTTCTGCTGGAAGGCGTTCGCCGACGGGGGCACGCTCCGGAAGCACGAACGTATCCACACGGGCGAGAAACCGTACGCCTGTCCGGTGTGCCCGAAGGCGTTCAATCAGCGGGTGGTGCTGCGGGAACACATTCGCGCCCACCATTCCCAGGCCGATTCGAAGCCAAACTCGACGGAAAAGGCGAACTACTGCTGCACGGTGTGCCCCAGTGGGACGACGGCGCCCTTTGCAACACCGCGCGAGCTCGTGCAGCATCTGATCGAGCACAGTGACACGAACACGGCCCTGCAGCGTCAACCACCGACCTTTCCGCGCAAGTACAAGCGCCGGCGGAAGCTGAAACCGCACGAGCTGGAACGCCTGCAGAGCGGTCGGAGGAAACAGAAGGCAAAACCGACGCatgatgaggaggaggaggagcaggaggaggaagagggcGAGGGAgatgaggaggacgacgatggGAATAAAAATCTCGGGTACGGATGCGGTGGGAAGGCACCACCGCAGCACAGCATGCTGGACGATAATGGCATCAATCTGCTGAGTAacgtcgtgctgctgcagcaaggTGCAAGCGGCAACCACAGCAACGCCAACAGGACAGTCACCGAATCTCCGCCACACAAAAAGCAGCCACCGGGACGAGCGAAAGCAGAACCGACCACGTCCCGGATGATTAACACAACGCAGAAACGCGCAACGGCTGGCAGGAAGACGGCCGCAAGGCAGCAAAGCTCGCGGAAGAGGACGTCATCCTACAGCAGAAAAGGTGCCCCCGGGAAGGGAACCTGTGAACTGCTTAAGGAGGGGGAAGAGGatgagcaggagcaggagcgggATGATAAGCCATTACCTTCCAACCACAGCGCCATTTCGAACGTGATGGAAGCGTTGTTCCGCGGCCGCAACCGGAAATCAATGCTGTCGGAGATACCGTCCCATCGGATCTCGTCCGTAAGCTTTCCGCTGCTAGATGACGGCAACACGGACGATCCGATGCTGGATGAACCGTCGCTTGAAGAGAATCctagcagtagcagcaccagcaagcAGCATCGTGGTCCGCAACACCCACAGCGTCCGGAGGATGACGACCTAACCCAGCAGCTTCTGATGGAAATTTCACGCAAAGATAAATACATCGAGCGCTTCAACAGCGACACAGTGAACGATCTGGAGGAGATCCTTCGCTCACCGGTCAAGCCGAAGCCGAGCCAATCCGCCGGGAAACGGGCGGTGAAGATGAAAAGCGCacccgccgctgctgctgctgctaccggtcGCCATCGAAAAACTACACCGGCAACGGGGAAAGCAACCGCAAAAGAAGCCCCAccgcagccaccgccgccgcagGTGCTACGTAGTCAGCGACTTACCCGCCGTCAGCTCGTGCGGGAGGTGAACTTCCTGAAGGAAGCGTACGGTGGGACGTCCCACGAGGAAACGAATCCTTCGCTCACCGCTCGTGGAGAATCGGTTGCGCCGGAACCGAACGCCACTACCTCTTCCTCACCGACCGGGGGCGTGAAAATGGAGCAGGCGGAGCGGCTGGCCGCAATGTTGCTGAACGACGGTATgatggacgacgacggccagAAGGAGGAGTACGGTTCGGACGGTGAGTACACTGCGGCGAAGGTGTTGCGTACCGTGAAGGAGGAACGTACCGATTCGccagccgacgacgacgacgaagaagatACTGTGCCGGAGGCAAACGACCTACTCTATGGAACTACCTCAACCAATGCATCGACCTATCGCTGTTCGATCTGTGCCGCCTGCTTCGACGATCGGACCCAGCTGATTCTGCACGTGCCGGTACATATTTAG
Protein Sequence: MDHNPFPLWQVSATDPAARGSGSSTVNNTASISTLNYVPNMRAKMKIVNISTQMTRANESGNLYGATTATYLPAVTERQQLVHHQPRRMATIPQNANTMLNESILLQTHDGREYLVDESSIQNIDQIPPENLIYMTTTTTTPTTEEGVLADHLAMNGGDDFEVQSGGQPLDHQQGESVPDLQQSATTTYAEECEVTEEIITDDWVQSQGEECVQVTVDQLGASAIVVEDDIAVPLDQDQYTLSRPYPCDFCSRRFRKKASLQNHLMAHSNDRPHVCNLCGAQYGRRCDLINHLKQHAYAVTEQDELSVRGAGGEQDVDYELPELIPRPDYHQHHQQLKKQRARQSSDDEDMYIQNAMVNYNSQPPMQLISTTNYGSSSSYTNGDSLEQMVDDGGTKVIQQPEPPPLPPMPGTPGRKKVASRTGGYIKKEPLDTAEEPVTSEPTQFPVTTDGRKTFLCQECGISFARYKALVAHTRNHHHHQQQQQQHQYGCDICGALFWEQTLLQDHVRHAHGMTTPEKKFVPPSPGPASPPVKKHFNCDSCSAIFFQLDHLQSHLQQAHGLKRAIASSGKPQRQQELLLMSTRGHADDEEREEEESTDQDEGEEDFEDLDYTYEAYEESRTTDGPDSSQASEVTGSQEQPQQQEFPMACRDCNEMVASAIDLLEHVEMHGNSARYESPHECQLCGEKFFDESFIKRHVQERHRAELTDTSCAICGKRCKSQTTLIKHAWDHSRDRAHSCSKCGKTFHHQARLKRHMDSHRSKAVRCEICSQEFPDGRTLMNHRHSHSKSNEYPCTECGKTFGSRSSQQIHMRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHSQADSKPNSTEKANYCCTVCPSGTTAPFATPRELVQHLIEHSDTNTALQRQPPTFPRKYKRRRKLKPHELERLQSGRRKQKAKPTHDEEEEEQEEEEGEGDEEDDDGNKNLGYGCGGKAPPQHSMLDDNGINLLSNVVLLQQGASGNHSNANRTVTESPPHKKQPPGRAKAEPTTSRMINTTQKRATAGRKTAARQQSSRKRTSSYSRKGAPGKGTCELLKEGEEDEQEQERDDKPLPSNHSAISNVMEALFRGRNRKSMLSEIPSHRISSVSFPLLDDGNTDDPMLDEPSLEENPSSSSTSKQHRGPQHPQRPEDDDLTQQLLMEISRKDKYIERFNSDTVNDLEEILRSPVKPKPSQSAGKRAVKMKSAPAAAAAATGRHRKTTPATGKATAKEAPPQPPPPQVLRSQRLTRRQLVREVNFLKEAYGGTSHEETNPSLTARGESVAPEPNATTSSSPTGGVKMEQAERLAAMLLNDGMMDDDGQKEEYGSDGEYTAAKVLRTVKEERTDSPADDDDEEDTVPEANDLLYGTTSTNASTYRCSICAACFDDRTQLILHVPVHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -