Adir001268.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles dirus
Gene Symbol
-
Assembly
GCA_000349145.1
Location
KB672979.1:11955493-11962298[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.012 0.69 10.0 5.0 2 23 406 427 405 427 0.97
2 26 0.011 0.59 10.2 2.9 2 23 434 455 433 455 0.98
3 26 0.0076 0.42 10.6 0.8 1 23 465 487 465 487 0.97
4 26 1.9 1e+02 3.1 0.1 3 23 512 539 510 539 0.83
5 26 6 3.4e+02 1.5 2.0 2 23 546 567 545 567 0.88
6 26 1.5 87 3.4 0.4 1 23 573 593 573 593 0.85
7 26 9.1e-05 0.0051 16.7 0.2 1 20 605 624 605 625 0.97
8 26 0.067 3.8 7.7 2.9 2 23 634 655 633 655 0.96
9 26 2.2e-05 0.0012 18.6 0.9 2 23 661 682 660 682 0.93
10 26 0.052 2.9 8.0 2.8 2 23 691 712 690 712 0.95
11 26 6.1e-05 0.0034 17.2 1.9 3 21 720 738 718 739 0.94
12 26 0.0016 0.087 12.8 3.1 1 23 750 772 750 772 0.98
13 26 0.00081 0.046 13.7 2.5 1 23 778 801 778 801 0.98
14 26 9.1 5.1e+02 1.0 0.8 1 15 829 843 829 846 0.80
15 26 0.0009 0.051 13.5 3.0 2 23 1211 1232 1210 1232 0.97
16 26 0.024 1.3 9.1 2.5 2 23 1239 1260 1238 1260 0.97
17 26 0.051 2.9 8.0 1.3 1 23 1270 1292 1270 1292 0.96
18 26 0.97 55 4.0 0.0 3 23 1317 1344 1316 1344 0.81
19 26 0.74 42 4.4 0.3 2 23 1351 1372 1350 1372 0.96
20 26 1.6e-05 0.00092 19.0 0.3 1 20 1410 1429 1410 1430 0.97
21 26 0.0024 0.14 12.2 0.8 2 23 1439 1460 1438 1460 0.96
22 26 0.00094 0.053 13.5 0.4 2 19 1466 1483 1465 1485 0.94
23 26 0.84 47 4.2 3.1 2 23 1496 1517 1495 1517 0.95
24 26 1.4e-05 0.00078 19.2 1.1 3 21 1525 1543 1523 1544 0.95
25 26 5.1e-05 0.0029 17.5 2.0 1 23 1555 1577 1555 1577 0.99
26 26 0.00081 0.046 13.7 2.5 1 23 1583 1606 1583 1606 0.98

Sequence Information

Coding Sequence
ATGGCAGAGAACAAACAGTGTGCGCTTTGCTTAAGCACTGACTCCAGCTGGTTCCTAGACGTGTTTAACGATGACAATAGAATGCTTGATATTGCGGATATTGTGTCGAAGCATCTTTGGTTTGATCTAAAACCATCCAGCCATCCGAACGTTTGTTCCGAATGCTGGACGAGTGTGCATGACTTTCATCTGTTCTACACCAAGCTGGAGAGTGTTCATAATCAGGATATCGTGGATGTAAACTCGGTCGCGGAATGTGTGCTCTCCGATGTTAAAAACGTGAAACTCGTCCACGAACACCCGGAAGATCTTTTCCAAGCTACGGTACACGATGGCGAAAATCATTCTGATGGTATCGAAACGAGTGGTAGAAAGCAGATGCCAAGAAGGTCCACGAATGCTCCGCTTAAAGATCGAGCAGATACAGCCGGTTCAAAAGACCTAGACAAAAATCATTTCGTCTCGGTGGACGAACATGTCGATAGTGATGTCGATGGCTTCGATGAGTACAATCATTCGGACGACGATTTCCTCTCGAACTCaccgaaaacggaaagcaTTGTACCTGCGGAACAACCGGTGAAGCGTCGAAGAGGACgtccaccaaaacaaaaactcgaacTAGAAACAACGCTTCAATTGTCTGAAAGTCTTTCCACCACGAATAATGTGAGCGAAACAGCAAATGAGTCACAGGCATCGGAACAACCTGCCAAGCGCCGGCGGGGAAGACCGCCGAAAAGAAAGTTAGACGTTGCTACAAACGAGGAACAAGACGATATGCGAATAACGATCAAGCAGGAAATGGGCGTGCAAGCATGTGCTGAAATGGCAGCATCGGTGGAAACCCCATTGGCCACTCTCGCACAACCGGTCAAGCGAGGCAGAGGTCGCCCGCCCAAAGTAAAGCCTGACGCTGGGTCAGAAACTCTGGCCGAAAAGAAATCCTCCGCGGTCCGCAAACGAAAATCTATCCTGGTGCGGAGGGATCGAAGCAGCAGTTCCAGCGCGCAGGATGACGATCCTGACTACGATATGGTGCGTGACAAAAAGAAGCTGGTGGAGCAGAAAAAGCCCCGGAACGACCGGGACGAGCGTATCTTCCAGCACGTGACCGATTTCTCCTGCGGGTACTGTGTGGAGAAGGTGCTATTCAAGCGATTTATCGATGCGGACCGGCACTACAAGCTGGTACACAACGAGCCCGGCTTTCTGAAGTGCCCGAAGTGTGATAAGAAATGCCACACGACCGGCATGTTCCTCAGCCACATGGAAACGCACGAAGATCCGGACAAGAACAAGTGTCAAATCTGCGGCAAACAGACGGATTGCAACATTTCGCTCAAGAAACATATGCGCATCCACCAGAGCCAGCTGGACCAGGACCTGCCGTACCCGTGCAGCGTCTGCAAGCGAAAGTTTGAGTCGGAGGAGCAGCGTATCAAGCACGAGAAGCTGCACGTACCGAAGCCCCAAATCAGGAAAGAGAAAGGTCCCGACCATGAGCTGCTCGCGTTCTACAAACGCATCTACTGCGACATATGCGAGCAGGAGCGGCCAGACTCGACGTCGTTCGAAAACTTCTGGGACCTGCGGGTGCACATGGACCAGGAGCACAACAAGGGTGCGTACCTGAAGTGTCCGCTGTGCACCAAGAGACACCTCTACCGGCAGCACCTCATCGCGCACATTGACGTGCACAACAATCCGGAAAAGTATCGGTGCGAAGTGTGCAAAGAAATCTACCAGAATCTGGATCAGCACATGATCAAGGCGCACACGCCCAACACATCGTCACCGGCGGACAAAAAATACAAGTGCGACCAGTGCGGGCGAATGTTTAACTTTTTGGCCAATTTGAAAATGCACATCGAGTGCATCCACGGTTCGAAGGACATTCGTTGCAATATATGCAACAAATATTTCAATCTGAAAGCTTTCCACTTGCACAAGCGTACGGCGCACACGGACCAGATGCTGATGTGTGAACATTGTCCGAAAATGTTCAAGACGCGCAGCGCGCTCGAGGCGCACAAGAGCGCCCACGACGACTCCCTGGTGCAGTTTACGACGTGCAAGTACTGCAACAAGCAGCTCCGGCTGACCAACGTCAAGAAGCACATGAAAAATCTACACTCCGAGGAAGGACCGTCAAACTGTGAGTTGTGCGGCAAGACGTTCCGCAGCCCGTTCCACATGAAACGCCATCAGAAAAATTCCTGCGAGGCGACCATCAACTCGCGCAAGCACAAGTGCGAGATATGCGGCAAAGGGTTCTGCCTGAAGCTGACGATGATCGAGCACATGACGACGCATACGCGCGCGAACCAGTACCAGTGTGCGTTCTGCTTTAAATCGTTCGGCTACATCTCGAATCTGTACAAGCATCGCAAAAAGGCACATCCGCTCGAGTGGCAGGAGGTGCAGGCACGGCCAGAGGAAGGCATTGCGACGGTGATCGTTCTGAAACCATCGGCGCATCCGTACGTTTGTACCGACTGCTGGACAAGCGTGTACGATTTTCATCAGTTCTACACAAGACTTGAGAACGTGTACAATCAGGGAGCGGACGGCGCTGAAGTCGTGGAAGTGTTGGACATCGAGTTCCTGGATGAGGATGCTGAGGAGCTGcgatttcaaattaaaaacataccCGGCACCGAATCGAACGGCGAGAGTAAAGCGGATCCTGCCAGACCCAAGCGCACGGCTAACGTACCGCAGAGGTATCTAAAAAGCAATGTGTATGGACGCAAACCCCAAAAGAAAGGCTTAGCCGTGGAAGACGGTTATTTGGACGATGAGGGTGTGCACGATGCAGAGGCAGATCATTATGATTACGAAAGTAATGAACACGATAACGATACGCTCGAGCACGACGACAGCGCTGAAACATCGTACGTGGAGGAGGAAAAGCATGCGGATAAAATTGGACAACGTTcaacgatcgcgatcgatatCCTGGATCCTCAAGAGCAGCCGGTAAAACGTCGCCGAGGCCGTCCGCCGAAGCGGAAGCTGCCGGAGAACGAGGAGCAAGCGTCAggtgtggaaaagaaaaaacagaatctGACCGGAACGCAGGCATCGCTAAACTCCACCGTTTCCTCCACGGACCAACCGGTGAAGCGTGGACGGGGTAGACCACCGAAGCAGAGAACGCTGGACGCTGGAACCGCTCCCGCACCAGCTATCCGCACTCCACCCGTGAAGAAAGAGGTAAAAACAGAGATTGgctacgacgacgatgaagatgcTACACCGAACACGTCGAAAGCGTCACAGCCCGAACGAAGGTCGACCCGCGTCCGTAAGATAAAGCACATCAGCGAAAGCGAACCCGACAGCGCACAAGACGAAGAAAGTGCAGTGAACGACAGCGATTTCGAAGAGTGCGATGACCCGGAGTACGAGGAAAAGTTGGAGCTGCAAAAGAAGCTGAACATGGACGATTACGAGTTCTACGAGTATCAGTGCAGCATGGAGTCGGAGCAGTGTGCGCGCGACAACCGGATATTCCAGTACGTGGATGAGTTCGTCTGTCACTACTGTGTGGAGAAGGTGCACTTTAAGCGGTTTGCCGACGCGGACGTGCACTATCGAGTGGAGCACAAGCAGCCACCGTTCCTGAAGTGTCCGACGTGTGACAAGAAATGTCACAACCCGGGCATGTTCATCAGCCATATGGAAACGCATGATGATCCGGAGAAGTCGAGGTGCCCTATTTGCAGCAAGCAGACTGATTGCAACATCTCACTGAAGAAGCATATGCGCATACACCAGAAGAAGCTGGAGGAAAACCTACCATATCCGTGCAGTCGCTGCAATCGCAAGTTCGAGACGGAGGAGCAGCGCGACAAGCACGAGAAGCTGCACGTACCGAAACCATACGTTCCGCGCGACCAGGGCCCTGACCTGGAGGTGCTCGAGTTCTACAAGCGCATCTTCTGCGACATATGCGAGGAGGGCGAACCGGGTTCGACCTCGTTCGACAACCTGTGGGATTTGCGGACGCACATGGCCAACGAGCACCGGAAGAGCCTGTTTATGCGGTGCCCCGTGTGCTACAAACGGCAGATCAACCGCACACAGGTCATCACGCACATTGACATGCACAAAAATCCGGAAAAATATCGATGTGAAGTTTGCCAGGAAGTGCATCAGGACCTGCCGGGGCACATGATGAAGGCGCACACGCCCAAAACGAAGGAACAGCCGGAGAAAAAGTACAAGTGTGAGCAGTGTGGGCGAATGTTTAGCTACCTAACCAACTTGAAAGTGCACATCGATTGCATTCACGGGCTGAAGGATGTTCGTTGCAACATTTGCGATAAGTACTTCAACTATAAGGCGTACCGTGCCCACAAGCGTACCGCACACACCGACCTGATGCTGATGTGCGAGCACTGTCCGCGGATGTTCAAAAATCGTAAAGCGCTCGAGTCTCACAAGGGCTGCCACGACGAGAGCCTGGTGAAGATGACGAAATGCGAACTGTGCGGGAAGCAGATACGCACCTGCTCCATGTCGAAGCACATGAAAACGATCCACTCGGAGGAGGATCCCATCGACTGTGACCTGTGCGGCAAGACGTTCCGCACCCCGTTCCACATGAAGCGCCACCAACGCAACACGTGCGAAGCGACGATGGATTCGCGCACGTTCAAGTGCGAGGTGTGCGGCAAGGGTTTCTGCACCAAGCTCACGATGATCGAGCACATGACGACGCATACGCGCGCGAACCAGTACCAGTGTGCGTTCTGCTTCAAATCGTTCGGCTACATCTCGAATCTGTACAAGCACCGTAAAAAGGCGCATCCGCTCGAATGGCAGGAGGTCCAGCAGCACCCGGAGGAGGGCATTGCGACCGTCATCGTTGTGAAGAATTGA
Protein Sequence
MAENKQCALCLSTDSSWFLDVFNDDNRMLDIADIVSKHLWFDLKPSSHPNVCSECWTSVHDFHLFYTKLESVHNQDIVDVNSVAECVLSDVKNVKLVHEHPEDLFQATVHDGENHSDGIETSGRKQMPRRSTNAPLKDRADTAGSKDLDKNHFVSVDEHVDSDVDGFDEYNHSDDDFLSNSPKTESIVPAEQPVKRRRGRPPKQKLELETTLQLSESLSTTNNVSETANESQASEQPAKRRRGRPPKRKLDVATNEEQDDMRITIKQEMGVQACAEMAASVETPLATLAQPVKRGRGRPPKVKPDAGSETLAEKKSSAVRKRKSILVRRDRSSSSSAQDDDPDYDMVRDKKKLVEQKKPRNDRDERIFQHVTDFSCGYCVEKVLFKRFIDADRHYKLVHNEPGFLKCPKCDKKCHTTGMFLSHMETHEDPDKNKCQICGKQTDCNISLKKHMRIHQSQLDQDLPYPCSVCKRKFESEEQRIKHEKLHVPKPQIRKEKGPDHELLAFYKRIYCDICEQERPDSTSFENFWDLRVHMDQEHNKGAYLKCPLCTKRHLYRQHLIAHIDVHNNPEKYRCEVCKEIYQNLDQHMIKAHTPNTSSPADKKYKCDQCGRMFNFLANLKMHIECIHGSKDIRCNICNKYFNLKAFHLHKRTAHTDQMLMCEHCPKMFKTRSALEAHKSAHDDSLVQFTTCKYCNKQLRLTNVKKHMKNLHSEEGPSNCELCGKTFRSPFHMKRHQKNSCEATINSRKHKCEICGKGFCLKLTMIEHMTTHTRANQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQARPEEGIATVIVLKPSAHPYVCTDCWTSVYDFHQFYTRLENVYNQGADGAEVVEVLDIEFLDEDAEELRFQIKNIPGTESNGESKADPARPKRTANVPQRYLKSNVYGRKPQKKGLAVEDGYLDDEGVHDAEADHYDYESNEHDNDTLEHDDSAETSYVEEEKHADKIGQRSTIAIDILDPQEQPVKRRRGRPPKRKLPENEEQASGVEKKKQNLTGTQASLNSTVSSTDQPVKRGRGRPPKQRTLDAGTAPAPAIRTPPVKKEVKTEIGYDDDEDATPNTSKASQPERRSTRVRKIKHISESEPDSAQDEESAVNDSDFEECDDPEYEEKLELQKKLNMDDYEFYEYQCSMESEQCARDNRIFQYVDEFVCHYCVEKVHFKRFADADVHYRVEHKQPPFLKCPTCDKKCHNPGMFISHMETHDDPEKSRCPICSKQTDCNISLKKHMRIHQKKLEENLPYPCSRCNRKFETEEQRDKHEKLHVPKPYVPRDQGPDLEVLEFYKRIFCDICEEGEPGSTSFDNLWDLRTHMANEHRKSLFMRCPVCYKRQINRTQVITHIDMHKNPEKYRCEVCQEVHQDLPGHMMKAHTPKTKEQPEKKYKCEQCGRMFSYLTNLKVHIDCIHGLKDVRCNICDKYFNYKAYRAHKRTAHTDLMLMCEHCPRMFKNRKALESHKGCHDESLVKMTKCELCGKQIRTCSMSKHMKTIHSEEDPIDCDLCGKTFRTPFHMKRHQRNTCEATMDSRTFKCEVCGKGFCTKLTMIEHMTTHTRANQYQCAFCFKSFGYISNLYKHRKKAHPLEWQEVQQHPEEGIATVIVVKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-