Adir002749.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles dirus
Gene Symbol
-
Assembly
GCA_000349145.1
Location
KB673312.1:7222105-7234141[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 3e-06 0.00017 21.3 1.7 1 23 376 398 376 398 0.98
2 9 2.9e-08 1.6e-06 27.7 1.6 3 23 406 426 404 426 0.98
3 9 3.5e-05 0.002 18.0 0.4 1 23 432 454 432 454 0.98
4 9 0.00014 0.0077 16.1 0.2 3 23 462 484 460 484 0.95
5 9 2.2e-05 0.0012 18.6 1.7 2 23 592 613 591 613 0.96
6 9 2.8e-09 1.6e-07 30.9 1.6 1 23 619 641 619 641 0.98
7 9 0.0019 0.11 12.5 0.8 3 23 649 669 647 669 0.97
8 9 0.00013 0.0074 16.2 0.8 1 23 675 697 675 697 0.99
9 9 0.051 2.9 8.0 1.4 1 23 704 728 704 728 0.95

Sequence Information

Coding Sequence
ATGGCGATCAATTTTTCCGCCTCGTTTGCGGCCTGTCTGGCGGCCGGCTTGAAAGTGCCGCGGCAGATCATGTACTGCATCTCGCAGGACACCGCCCCGTACGTGCTGTACAAGGACTCGCAGGAGGCGGCCGAACGTGGGgctgccgccgcagccgccgtcCAGTGGGGCAATGCGGACGGTCCCGCCCTCTACCAGCAGAACGCACAGAACCACCTGCAGGCGCACATGAACGGGGCggcaacgcagcagcagctcgttgctgcggccgccgccgccgccgcgcaacaccatcagcagcagcagcagcagcagcatcaccagcaacagcagcagcagcagcaaactgcCGCCAATCATAGCCCCCCGAACCAGGACAATAGGCCACAGCAACCGGGTGAACAAGCGAATGGTCATCTACACAGCCCGGCCACTAGCCCGTATCCTGCGAATAACGGTCCAGACATAGAAGAAGATTTGATCAAGgtacaaagtatgcaacagGCCgttcagcatcagcagcagaacgGGCAGCAACAGTtggtccagcagcagcaacagcaacagggtGGCAACAACTCCTCCGGGAGTCACCCGAACGATCCCAACCAGCAGCAATCTGCGGGCGGTCCGGCCGGTGGTGGGACAggtagtggtggcggtggcggcggcggcggtggaggacCTCCAGGACCACCGCCCGGGTGCTTCGGGAACGAGGCCGCCTCCCAGGCCGAGCTGAACTACTACGCGCAGCGGCATCACGCGGCGGCAGCCGCTGGACCTCAGGGTGCCATGTTGCCACCGCCGGGCTTCGCGCCCCTCCATCACTATCTCAACAAAACGGGCGTCCTGCCGGTGGGCATGCCGACCGGGCTGGACCAATCCGGCGCCCTGGAGCAGTACGGCATGCCGGACCTGTTGCACGGCGGAGGTGCGACCGCTCCCGGCGGACCGCCcggggccggtggtggtggtgcgaacagcaaccagcagcagcaacagcagcagcagcagcaacagctgcaccACTCCCCGACCAACGGGGTGGTGCCCGGTCCGAACGGCGCCGTCGGCGGTGGAACCACCGCCACGTCCAAGTCGAAAAACTCCGACCTGCGGCTGTTCAAGTGTCTGACGTGCGGGAAAGACTTCAAGCAGAAGAgcacgctgctgcagcacgagcGCATCCACACCGACTCGCGCCCGTACGGGTGCCCGGAGTGCGGGAAACGCTTCCGCCAGCAGTCGCACCTCACGCAGCACCTGCGGATACACGCGAACGAGAAGCCGTTCAGCTGCGCGTACTGTCCGCGCAGCTTCCGCCAGCGGGCGATCCTGAACCAGCACATCCGCATTCACTCAGGTGATAAGCCGTTCGGCTGCCCGTATCCGGAATGCGGCAAAAAATTTCGACAAAAGGCCATATTGAACCAACACGTGCGCACCCATCAAGATGTGTCTCCCCATTTGATCTTCAAGAACGGGCCGCACGCAACGCTCTGGCCGCAGGATGTACCGTACCCGCCGGAGCTCGAAAACGCACAGCCTAAGGACGAGCAGACGTTCGGCGATGAGGCGTCGCAGGGCGGTGGCGAATCGCGCGGTTGCTTCTCGCCGGACAACTATCCGGCCTACTTCAAGGACGGCAAGGGTGTGAACCATTCGATCTTCGGCAACAATCTGCAGTATCTCAACAAGGCGACCGGCGGAAAGGCGATGCTGCCGGACGTGATCCAGCACGGTCGGTCGGCGGGCATGCCGCTGTACGTGCGCTGTCCGATCTGCCAGAAGGAGTTCAAGCAGAAGAgcacgctgctgcagcacggctGCATCCACATCGAGTCGCGCCCGTACCCGTGCCCGGAGTGTGGCAAGCGCTTCCGGCAGCAGTCGCACCTCACGCAGCATCTGCGCATCCACACAAACGAGAAACCGTTCGGTTGTATGTACTGTCCGCGGTTCTTCCGACAGCGCACGATCTTGAATCAGCACATTCGTATTCACACTGGTGAGAAGCCGTACCGGTGTGGCCAGTGCGGCAAGGATTTCCGGCAGAAGGCTATCCTCGATCAGCATACCCGGACGCACCAGGTAGGCGATCGACCGTTCTGCTGCCCAATGCCCAACTGCCGGCGCCGCTTCGGTACCGAGCAGGAGGTTAAGAAACATATCGACAACCACATGAACCCGCACTCGTCCAAATCGCGCAAGCAAGCTGctcacaacaacaataacaacaacaatagtagcaacaacaataacaataacaacagtaGTAACAATAACAATGCGGACAACAACACGGACGCTGCCGGACGCAACAATGGCGGAGCGAACGGAAACAATGCCACCAATGGCAATGCGActgcaaacaataacaacaacaacaacaacaacaataacaacaacaataataataacaacaacaatggcaTTATCGAGCAGAAGGTATCGCCGACGTTCCTGATGGACAAGCAGAACCAGCTGATCCAGCGTATGGCAACGCCGGTCAAGCACGAGCTGTACTTCCCGCAGTGCTACGGCCCACCGTTCAATCAGTCGTTCGTGGCGGGCGCAGCCGCCGTTGCGGCGGCCAACGCGAACGGTCAggcggctgcggctgccgctgcagcagcggccgcagcagcagcagcgtcggtcgtcggtggtggtggtggaccacagaaccagcagcagccgggtaCAGGCAATCCACAGggacctccaccaccaccatcccaGCACGGCGGCAATGTACCGGTGGTGCCGCCACCGGTATCGGCcgcagctgccgccgccgtcgccgcagcGATCGTAGCCGCACCGGTACCGCAGGCCGTCGTGGCGCAGTGA
Protein Sequence
MAINFSASFAACLAAGLKVPRQIMYCISQDTAPYVLYKDSQEAAERGAAAAAAVQWGNADGPALYQQNAQNHLQAHMNGAATQQQLVAAAAAAAAQHHQQQQQQQHHQQQQQQQQTAANHSPPNQDNRPQQPGEQANGHLHSPATSPYPANNGPDIEEDLIKVQSMQQAVQHQQQNGQQQLVQQQQQQQGGNNSSGSHPNDPNQQQSAGGPAGGGTGSGGGGGGGGGGPPGPPPGCFGNEAASQAELNYYAQRHHAAAAAGPQGAMLPPPGFAPLHHYLNKTGVLPVGMPTGLDQSGALEQYGMPDLLHGGGATAPGGPPGAGGGGANSNQQQQQQQQQQQLHHSPTNGVVPGPNGAVGGGTTATSKSKNSDLRLFKCLTCGKDFKQKSTLLQHERIHTDSRPYGCPECGKRFRQQSHLTQHLRIHANEKPFSCAYCPRSFRQRAILNQHIRIHSGDKPFGCPYPECGKKFRQKAILNQHVRTHQDVSPHLIFKNGPHATLWPQDVPYPPELENAQPKDEQTFGDEASQGGGESRGCFSPDNYPAYFKDGKGVNHSIFGNNLQYLNKATGGKAMLPDVIQHGRSAGMPLYVRCPICQKEFKQKSTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHIRIHTGEKPYRCGQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFGTEQEVKKHIDNHMNPHSSKSRKQAAHNNNNNNNSSNNNNNNNSSNNNNADNNTDAAGRNNGGANGNNATNGNATANNNNNNNNNNNNNNNNNNNNGIIEQKVSPTFLMDKQNQLIQRMATPVKHELYFPQCYGPPFNQSFVAGAAAVAAANANGQAAAAAAAAAAAAAAASVVGGGGGPQNQQQPGTGNPQGPPPPPSQHGGNVPVVPPPVSAAAAAAVAAAIVAAPVPQAVVAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101827;
90% Identity
-
80% Identity
-