Adir011852.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles dirus
Gene Symbol
-
Assembly
GCA_000349145.1
Location
KB672946.1:1518690-1533941[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.015 0.85 9.7 0.2 2 23 397 418 396 418 0.96
2 12 0.00019 0.011 15.7 0.9 1 23 430 452 430 452 0.97
3 12 5.4e-05 0.003 17.4 0.3 2 23 461 482 460 482 0.97
4 12 3e-05 0.0017 18.2 1.9 1 23 488 510 488 510 0.98
5 12 5.7e-06 0.00032 20.5 1.4 1 23 517 539 517 539 0.98
6 12 4.7e-06 0.00026 20.7 0.9 1 23 545 567 545 567 0.97
7 12 5.5e-05 0.0031 17.4 0.1 1 23 573 595 573 595 0.97
8 12 6.3e-06 0.00035 20.3 0.4 1 23 601 624 601 624 0.96
9 12 4.5e-05 0.0025 17.6 1.9 1 23 630 653 630 653 0.96
10 12 0.00075 0.042 13.8 4.7 1 23 659 681 659 681 0.99
11 12 5.8e-05 0.0032 17.3 0.3 1 23 687 709 687 709 0.96
12 12 0.00048 0.027 14.4 0.8 1 23 715 739 715 739 0.92

Sequence Information

Coding Sequence
ATGAGCGACAGTGATCCGCAGCTGGACGGGGTGTCCTTCGACGGTGAGGCACAACTACATCCGTGCTGCTATGTGTGCCATTTTCCAGCGACCCAGGATGAGTTTTATCCATTGTTCGCCGAGCCGGACGAGGGTGTCTTCACGCCGGCGAAGATACTGTGTGATATTTTAGACATTGAGGTTATCCCGGATTTGTGCCACTCGCAGATCATATGTGTAAACTGCAACATGTTGTGCATAGAGTTCCAATCGCTATTGCAGCGCATGGAAGCGATACGCATCGAGATGACGATGGCTTACAATCAAACCGTAATGAAGCTGACCGGGCTGACCGAGAAGGATCTTAAGGAGGGTATCGTGGAGGTGGAGGACACCGAGGCGAATCTCGATAGTGAGTTGCAAAGCTTTAATAAGGAGTTGATGTCGATGGAGGAAGTGTTCCGGATGGAAGGGCTTGTGCCGGATTCAATCGAGGTGGATCCATCTACTGAGCAAATGGACAGTGCACTTCCCAAACTGGGTATCGTCTGGCAATCGGAAGTAGATGGAACGGAAGTTTCTACAAATTCGTTGATTAATTCGAGTGCGCTCGTGGATGCCACAGAGTGTGGTACGGTGAAGGAAACCCATGAGCCGGAAATCATGCACGTACGGGAAGACAATCTAACAGAGCCTCTCGAACCTTCTGGTATTGTGGACGCGAGTGAACACGAGTTGTCGACTGAGGACACGCTTGAACGGTTTATAAGCGAATCGAACGACGGTATAGTTGAAGTTACGGGTGAAGATGGAACTGCACTTTATTGCATTTACGATGACGTTATCGAAACGTACAGCGATTCGGAAGAGCCCACGGATATAACTATGTTAAATTGTATCAACGAAGACGGTGCGTTAGATTGTGATGAAGTCATAATCGACAGTACATCGCAGGCAAGCAAAGCCGGGCAGACAGAGATCGAGGAAACCGTTACACCACCTTCCCAGACGCACGGCAACGGAAATTCTGCTGATTCAGCGCTTGTGTCCACAACGCCGACCTCCGATGGAGCGACTTTACAGCCGCTTTTCATCAAAATAGAAAACTCCTACTACTGCACGCTGTGCTCGACGGACCGTCAGGCGAAATCCCACAATGTAAAAACGATTGCGCAGCACTTGAAGAAAGAGCATAACCAACAAATTCTCGTATGCGAGCAGTGCGATGCGATATTTTTCCTGCGCTCCACCTACACAGAGCACATGGAGCAGCACAAGATGGTGGAGGTGACCTATCAACCAACCGAGCACAGTTGTGACGTTTGTGGCGAAAAGTTTACCGGCTTGCgcttgctgcagctgcaccgtAAGGTGCACACAAACGGGGCCAGTAAAATTTGGTCATGCGAGATCTGCGATAAGAAGTACGCGTCGAAGGCATTCTACGAGGTGCACATGAACAAACACTCCGGCCTGCGGCCGCACAAGTGCACCGAGTGCGCGAAAGACTTTACGTCCAAGTACGTGCTGGCGGTGCACATGAAAACGCACAAGGATCGTCCCCGGGCGTTTGAGTGCAGTGACTGCGGCAGTTCGTTCTACAGCCGCAACAATCTGGTACAGCACAAGCGGACGCACCGAGGCGTGCGAGATTTCGAGTGCAGCGAGTGTGGCAAGACATTCCTTTCGCAGCACAACCTGAACGTGCATATGGTGATTCACAGTGCAACGAAGGCGTTCGCCTGCAGGACGTGCGGGAAAGCGTTCGCACGGAAGGCCGAAGTACTGGATCACGAACGCACGCATACAGGTGAAAAGCCCTTTGCGTGCGATATCTGCGATGCAAGTTTTGCTCAACGCTCGAATCTCTACTCCCATCGACGCTTAACGCATTTGAACGATAAACGCTTCAAATGCGACGTGTGTGGCGCATGCTTCAAGCGACGACGGTTGCTGCTTTATCATACCAGGGCGGCCCACACAGGCGAACGGCCGTACAAGTGCGATTTGTGCACGGCCACCTTCGTCTATCCGGAACACTTTCACAAACATAAACGCATCCACACCGGAATGAAACCGTACGCCTGTGAGGTGTGCCAGAAAACGTTCAACAGTCCGGATAATCGGAACGCGCATCGTTACGTGCACAGCGACAAAAAGCCTTTCGAATGTGTAACGTGCGGATCGGGTTTCATGCGCAAATCACAACTATATTCGCACATGCAGAAGCGGGGACACCTAAATGATACGATCGTGGTCAATCAGCCACGCATTAACGCGAATGATACGCTCGAgttcgaaaccgaaccggtggCCACGGATGTCCCGCTGGACGGTGGTGAACATAGTCAAGATGAGATGCAAATTGCCTGCGACGAGGAGAATGCCGACGGTGGTGTTATCGGAACGGAGCAGTACTACCAACGAAGTGAACAACAGACCGGTGGTGCAAGTAGCAGCAGTATCGGTAACATGCAGTTCATAACAAAGATTGAAATTAACGACACAGATTGGGATAATTTCATTGAGGAAGATTAG
Protein Sequence
MSDSDPQLDGVSFDGEAQLHPCCYVCHFPATQDEFYPLFAEPDEGVFTPAKILCDILDIEVIPDLCHSQIICVNCNMLCIEFQSLLQRMEAIRIEMTMAYNQTVMKLTGLTEKDLKEGIVEVEDTEANLDSELQSFNKELMSMEEVFRMEGLVPDSIEVDPSTEQMDSALPKLGIVWQSEVDGTEVSTNSLINSSALVDATECGTVKETHEPEIMHVREDNLTEPLEPSGIVDASEHELSTEDTLERFISESNDGIVEVTGEDGTALYCIYDDVIETYSDSEEPTDITMLNCINEDGALDCDEVIIDSTSQASKAGQTEIEETVTPPSQTHGNGNSADSALVSTTPTSDGATLQPLFIKIENSYYCTLCSTDRQAKSHNVKTIAQHLKKEHNQQILVCEQCDAIFFLRSTYTEHMEQHKMVEVTYQPTEHSCDVCGEKFTGLRLLQLHRKVHTNGASKIWSCEICDKKYASKAFYEVHMNKHSGLRPHKCTECAKDFTSKYVLAVHMKTHKDRPRAFECSDCGSSFYSRNNLVQHKRTHRGVRDFECSECGKTFLSQHNLNVHMVIHSATKAFACRTCGKAFARKAEVLDHERTHTGEKPFACDICDASFAQRSNLYSHRRLTHLNDKRFKCDVCGACFKRRRLLLYHTRAAHTGERPYKCDLCTATFVYPEHFHKHKRIHTGMKPYACEVCQKTFNSPDNRNAHRYVHSDKKPFECVTCGSGFMRKSQLYSHMQKRGHLNDTIVVNQPRINANDTLEFETEPVATDVPLDGGEHSQDEMQIACDEENADGGVIGTEQYYQRSEQQTGGASSSSIGNMQFITKIEINDTDWDNFIEED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-