Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB673312.1:1344227-1349162[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1.7e-06 9.3e-05 22.1 2.6 1 23 201 223 201 223 0.99

2 13 0.014 0.81 9.7 0.5 1 23 229 252 229 252 0.98

3 13 0.00015 0.0081 16.0 0.7 1 23 272 295 272 295 0.93

4 13 0.016 0.91 9.6 3.8 1 23 301 324 301 324 0.95

5 13 4e-06 0.00022 21.0 0.2 1 23 500 522 500 522 0.99

6 13 2.7e-05 0.0015 18.4 0.7 1 23 528 550 528 550 0.99

7 13 0.0095 0.53 10.3 2.5 1 23 639 661 639 661 0.98

8 13 2.4e-06 0.00013 21.7 1.1 1 23 667 689 667 689 0.99

9 13 0.00037 0.021 14.8 0.1 1 23 797 819 797 819 0.94

10 13 0.00061 0.034 14.1 1.8 1 22 825 846 825 849 0.90

11 13 4.7e-07 2.6e-05 23.9 0.8 1 23 997 1019 997 1019 0.99

12 13 0.00011 0.006 16.4 4.0 1 21 1025 1045 1025 1047 0.94

13 13 0.0024 0.14 12.2 1.7 2 23 1237 1259 1237 1259 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1.7e-06	9.3e-05	22.1	2.6	1	23	201	223	201	223	0.99
2	13	0.014	0.81	9.7	0.5	1	23	229	252	229	252	0.98
3	13	0.00015	0.0081	16.0	0.7	1	23	272	295	272	295	0.93
4	13	0.016	0.91	9.6	3.8	1	23	301	324	301	324	0.95
5	13	4e-06	0.00022	21.0	0.2	1	23	500	522	500	522	0.99
6	13	2.7e-05	0.0015	18.4	0.7	1	23	528	550	528	550	0.99
7	13	0.0095	0.53	10.3	2.5	1	23	639	661	639	661	0.98
8	13	2.4e-06	0.00013	21.7	1.1	1	23	667	689	667	689	0.99
9	13	0.00037	0.021	14.8	0.1	1	23	797	819	797	819	0.94
10	13	0.00061	0.034	14.1	1.8	1	22	825	846	825	849	0.90
11	13	4.7e-07	2.6e-05	23.9	0.8	1	23	997	1019	997	1019	0.99
12	13	0.00011	0.006	16.4	4.0	1	21	1025	1045	1025	1047	0.94
13	13	0.0024	0.14	12.2	1.7	2	23	1237	1259	1237	1259	0.96

Sequence Information

Coding Sequence: atgGAGCTGAAggcagagaaaaaagagcacgacgacgatgaaagTGGCGGCGGTGGACGTGGACGGCTGCATCGTCGTAATAGCACCGTCgttgcagcagctgccgttgctgctgctggcgacgAGATGTCGGATCAGGAGATAGTGGAGGTTGGCATCGACGAGGATCACATCAAGTTTCTCACCAGCATGCACTCGGGCGATGAGGAACCGACGAATGggaaccatcaccatcgcgcTGCGGTCGCGCCCACTGGTCGGACGCACCGTGCGGGGATGGTGAACGGCGTATTTGATGGGGCAAACGTCCGGCGGCAGGTACAAAGTGTAGCCGGCAGCAACGCCCCCAACCGGCCGTACATTCCAGCGCATCAGAACGGCGGTGGAACGCACCACCAGAATGGCAAAGTGCAGCGACGGGTTGTGAACGGTGCGCCCGACTACAGCGAGGACGATTCATCGGACGttgacgacgatgaggatgacgacgacgacgacgacgatgatgacgacgatgacgacgaggatgtGATGGTCGTCGCTGCGAACATCCTATCGAAGACGGCGCAGAGGTCATCGTTGCTTGGAACCGGTCGCACGTACCAGTGTGACGTGTGCCCGCGGATCTTTCACCGGCCGGACCACTTGCGCTACCACATGCGCATCCACGAGAAGAACAACCCGTTCGAGTGTAAGCTGTGCTTCAGCGTGTTCGCGTCCGATCCGGCGTTCGCGCACCACATCCGGACCGAGCACGCCGGCATGGGGCTGGCGGACgcgctgccaccggtgccggaAACGGAGGCTCACTACTTCGCCTGCACGTACTGCGACAAAACATTCTCGGACGGGGTCGAGCTTGAGGAGcacctgcaccagcagcatctggGCGAGCGGCCGTACAAGTGCAACATGTGCCCGAAGGCGTTCATACGGATGGATTTCCTGCAGTGCCACTACCAGAAGTACCACAGCTTTCATCCGATggtggacgacgaggaggaggacgacgaggagggcGAGGAAGGGGAGGACGGAGAAGAGGAGCGACAGCGGTTCGATCAGGCGCACCGCGCGAAGCGGCCCCGGTTGATGGTGCGTAAGCTGGAGGAACTGGTGGATGGGGCGCGCATGATGaaggtgacgacgacgacgacgacgggggcGGCCCGCCGTTCGTCccacaccggaaccggcacgAGCATATCGAGCGACGAGTACCGGCGGGATgagtacgacgacgacgtggacgacgaggaggacgacgggGACGACGAGGGTACGGGTGCGGAAAGCAGCgatcagcaccatcagcagcagaaggTTCCGGcacagcagcaccggaagGGTTCGGGGCGAGGACTGCAGCCAAAGCTGAGCAGTGTGCACAGCCGGTTTCTGGTGGCGATGGAAGAACAGCGGGCGAAAAAgatggcggcagcagcggcagcggcggcggcggctgcagctgctgctgcggcgaaGGAATGCAACAAATATCGGTGTCCCGTATGCGACCGTGGCTTTGCCCATGAGCCAGAACTGATGCAGCATGTTCGAACCCACCCTGATCTACCCACGTTTAAGTGTCCACTGTGCGAGCTAACCTTCATCGGGTCGGATTACCTGAAGAATCATCTGAAAAAGCACGTCATTGGGAATGGCGAAGATCCGGGCGCACCGGGTGCCATCGATCTGAAGTTGATCGGTGTGCCGGACGCGAACACAACCACCGGCAGTACAGGCGAGACAGGCGGAACCGATGCGGTGCGTCCACTCACCACCCCAAAGCTGCCGAAGCCGATCATCACCTCGAAACCACCGTCCACCGGGATCTCGCTGCTAAAACCGATCGAGGAGCGCAAACCGCCCGACCACCAGCAGGAGTACTGCGTGAAGACGGCGGACGGGAAGTTTATGTGTACGGTGTGCGAGCGTCTGTTCTCGCATCAGCAAACCGTGCGCATCCACTTCCGCATCCACACGAACGAGAAGCCCTACAAATGTACCTTCTGCGACGAGTCGTACATCCGGTCCGACTATCTGGAGCGGCACCTGAAGGTACACTTCAAGGACGGAATGCTTCCGGCGGCCGCCATCGCGAGtatggcggcggcagcggcagcagctgctgcggcatCCGCTGCCGGTGGGACCCGGTCCGCTACCTCATCACCTCCAACGGTGCCGAAAGAAGAGCCGGGCACGTTCGTTGACCACCCGGTGGTAAGCACTCCGACGAATGCTGTTCCTGCCACTACGACGAGCGGTACACCCGGGACGGGAGGTGGCagtggtggaggcggcggcggtggaagtAAACCTTTGATAGGGCGTGCCGGGTTGGCACCGGAGAACTATCACTTTACCGAATCGAACGATGGGCAGTTTGTGTGCAAGATCTGCGATGCCGTGTTCAACCAGGTGGCCTTACTGCGCAAGCACGCGCTCGACCACACGGAGGAGAAGCCGTTCTACTGTGCCATCTGCGATCGGTCCTTCAACCGGGTGGACTATCTGAAGGAACACTTCAAATCGAAGCGtcacctgcagctgctggcggaaGCGGCCGACActtcggcggtggtggccgacgaggacgacgatgccACGATGGATGGCATGTCGTCGATGTCAAAGTCATCGGTCAACCGGTCCAAGGCGGcagggggaggaggaggtggaggcaAAACTGGTAGCAGCAACACCGACGTTAAACCGCCGGTAGGGACGAATGGGGACAGTAGCTTCAAGTTGGAGACAAAAAACggccacagcagcagtagcagtagcagtagcagtggtagcagcagccgaagtagcagcagcagtagaagcagTAGTAATAGCAATAGtaaaaccaacaccaccaccacaccgaaTCCGAGCCCGCAGAAGCAACCGAAGCGGGAGGAATCGCCGGGCGACTGTGCGATGCTGCAGGGTGAGTTCCACCGGTCGGATTACGAGCGCACCAGCGACGGGCGGTACAAGTGCAACCAGTGTGATAAGACGTTCGTGACGGCGGTCACGCTCAAGATGCACATCCGGCTGCACACGGGCGAGAAACCGTACAAGTGCGACAAGTGTGATAAAGCGTTCATCCGCTCCGACTACCTGAAAACGCACGAAAAGTGCCACCGGCAGGAATCGTTCCTGAGCATGCTGTCGCTGACGACGTCGAAGGAACCGAGCACGGCCTCGGAAGCGGGCGAATCCGACGGTGAGGAGGGCGAAGTGATGATCCACGCGGGCAGCGACGCACCGGTCAACGGTGGAGAACGCCCCGACGCGTCGGACGAGGAAGAAggcgaagaggaagaggaggagggagaggaggaggaagaagacgaagacgaaAGCGAGGACGAGCAGGTCATCGAGGTGATGGTGAAGGAGGCTAGCTGTTCGGAAAGTGAAGACGAGGAAGAAGATGGTggtgaggaagaggaagaggaagaggagggagacgatgatgacgacgatgacgaggaggATGGGCGTCGGGATGCCGCCAGCGCTGACAACAGTACAAATCGAAGCGTGTCCGGAACGATGGAGCACCAGCGAAAGGAGAAGGACAAGAGTAAACGAAAAAGCCGTCCAACCAGCGGTggcgacagcagcaacaatgggTACGACCACGAGGATGACAGCACGTCGCAGGCCAGCGGCCCCGTCGCCAGCCAGCAGTATGGCGGTGGTGCGGAATGCCATCTTTGCGACGTCAGCTGTACGAATGCAACCGAGCTGGTGCAGCATCAGTACACGGTACATGGTTTGCAGCCATTGGAAAGCTAG
Protein Sequence: MELKAEKKEHDDDESGGGGRGRLHRRNSTVVAAAAVAAAGDEMSDQEIVEVGIDEDHIKFLTSMHSGDEEPTNGNHHHRAAVAPTGRTHRAGMVNGVFDGANVRRQVQSVAGSNAPNRPYIPAHQNGGGTHHQNGKVQRRVVNGAPDYSEDDSSDVDDDEDDDDDDDDDDDDDDEDVMVVAANILSKTAQRSSLLGTGRTYQCDVCPRIFHRPDHLRYHMRIHEKNNPFECKLCFSVFASDPAFAHHIRTEHAGMGLADALPPVPETEAHYFACTYCDKTFSDGVELEEHLHQQHLGERPYKCNMCPKAFIRMDFLQCHYQKYHSFHPMVDDEEEDDEEGEEGEDGEEERQRFDQAHRAKRPRLMVRKLEELVDGARMMKVTTTTTTGAARRSSHTGTGTSISSDEYRRDEYDDDVDDEEDDGDDEGTGAESSDQHHQQQKVPAQQHRKGSGRGLQPKLSSVHSRFLVAMEEQRAKKMAAAAAAAAAAAAAAAAKECNKYRCPVCDRGFAHEPELMQHVRTHPDLPTFKCPLCELTFIGSDYLKNHLKKHVIGNGEDPGAPGAIDLKLIGVPDANTTTGSTGETGGTDAVRPLTTPKLPKPIITSKPPSTGISLLKPIEERKPPDHQQEYCVKTADGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCTFCDESYIRSDYLERHLKVHFKDGMLPAAAIASMAAAAAAAAAASAAGGTRSATSSPPTVPKEEPGTFVDHPVVSTPTNAVPATTTSGTPGTGGGSGGGGGGGSKPLIGRAGLAPENYHFTESNDGQFVCKICDAVFNQVALLRKHALDHTEEKPFYCAICDRSFNRVDYLKEHFKSKRHLQLLAEAADTSAVVADEDDDATMDGMSSMSKSSVNRSKAAGGGGGGGKTGSSNTDVKPPVGTNGDSSFKLETKNGHSSSSSSSSSGSSSRSSSSSRSSSNSNSKTNTTTTPNPSPQKQPKREESPGDCAMLQGEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKCHRQESFLSMLSLTTSKEPSTASEAGESDGEEGEVMIHAGSDAPVNGGERPDASDEEEGEEEEEEGEEEEEDEDESEDEQVIEVMVKEASCSESEDEEEDGGEEEEEEEEGDDDDDDDEEDGRRDAASADNSTNRSVSGTMEHQRKEKDKSKRKSRPTSGGDSSNNGYDHEDDSTSQASGPVASQQYGGGAECHLCDVSCTNATELVQHQYTVHGLQPLES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -