Basic Information

Insect: Anopheles dirus
Gene Symbol: Bcl11b
Assembly: GCA_000349145.1
Location: KB673423.1:401194-405830[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00024 0.014 15.3 1.4 1 21 63 83 63 84 0.95

2 18 1.7 96 3.2 0.2 1 16 91 106 91 108 0.88

3 18 2.5 1.4e+02 2.7 0.2 2 12 117 127 116 128 0.87

4 18 1.1e-06 6.3e-05 22.7 4.3 1 23 522 544 522 544 0.99

5 18 3.5e-07 2e-05 24.3 0.5 1 23 550 572 550 572 0.99

6 18 1.7e-05 0.00097 18.9 0.0 1 23 578 600 578 600 0.98

7 18 3.4e-05 0.0019 18.0 0.6 2 23 606 627 605 627 0.96

8 18 2.3e-07 1.3e-05 24.9 4.1 1 23 633 655 633 655 0.99

9 18 8.5e-05 0.0048 16.8 1.8 1 23 730 752 730 752 0.97

10 18 5.4e-06 0.0003 20.5 2.5 2 23 759 780 758 780 0.98

11 18 1.7e-06 9.4e-05 22.1 0.8 1 23 786 808 786 808 0.98

12 18 2.1e-06 0.00012 21.8 0.1 2 23 814 835 813 835 0.98

13 18 1.6e-06 8.8e-05 22.2 2.1 1 23 841 863 841 863 0.99

14 18 8.4e-07 4.7e-05 23.1 2.3 1 23 918 940 918 940 0.99

15 18 3e-07 1.7e-05 24.5 0.9 1 23 946 968 946 968 0.99

16 18 4.2e-05 0.0023 17.7 0.3 1 23 974 996 974 996 0.98

17 18 3.9e-06 0.00022 21.0 0.3 2 23 1002 1023 1001 1023 0.97

18 18 2.7e-06 0.00015 21.5 1.2 1 23 1029 1051 1029 1051 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00024	0.014	15.3	1.4	1	21	63	83	63	84	0.95
2	18	1.7	96	3.2	0.2	1	16	91	106	91	108	0.88
3	18	2.5	1.4e+02	2.7	0.2	2	12	117	127	116	128	0.87
4	18	1.1e-06	6.3e-05	22.7	4.3	1	23	522	544	522	544	0.99
5	18	3.5e-07	2e-05	24.3	0.5	1	23	550	572	550	572	0.99
6	18	1.7e-05	0.00097	18.9	0.0	1	23	578	600	578	600	0.98
7	18	3.4e-05	0.0019	18.0	0.6	2	23	606	627	605	627	0.96
8	18	2.3e-07	1.3e-05	24.9	4.1	1	23	633	655	633	655	0.99
9	18	8.5e-05	0.0048	16.8	1.8	1	23	730	752	730	752	0.97
10	18	5.4e-06	0.0003	20.5	2.5	2	23	759	780	758	780	0.98
11	18	1.7e-06	9.4e-05	22.1	0.8	1	23	786	808	786	808	0.98
12	18	2.1e-06	0.00012	21.8	0.1	2	23	814	835	813	835	0.98
13	18	1.6e-06	8.8e-05	22.2	2.1	1	23	841	863	841	863	0.99
14	18	8.4e-07	4.7e-05	23.1	2.3	1	23	918	940	918	940	0.99
15	18	3e-07	1.7e-05	24.5	0.9	1	23	946	968	946	968	0.99
16	18	4.2e-05	0.0023	17.7	0.3	1	23	974	996	974	996	0.98
17	18	3.9e-06	0.00022	21.0	0.3	2	23	1002	1023	1001	1023	0.97
18	18	2.7e-06	0.00015	21.5	1.2	1	23	1029	1051	1029	1051	0.98

Sequence Information

Coding Sequence: ATGCGCTTCGAAGCATTCGGAAGCGATTACGCAAAGCCCCAACTTCCACCGGCTGTTCCGCCACTTCCGATGCCAATGGCGCAACAGCaagcaccgcagcagcagcagcagcagcaacaaccgtGCAAATGCGAATTCTGCGAGTATCTGCAGGCGAACCGGATATCGCTGACCGGCGACCATTCGTTCCAGTGTGAGTTTTGCGGGGAAGGTTTCGCCAACCAAACCAGCTTCAACCGGCACCGCTGCGGCAGCACGGACATTCAGATATATCGGTGCGAAAACTGTCGCCGGGAGTACGGCAGCTCACGGGCCCTGTCCACGATCGGCAACTGCGAGCCGCGCGACAAATGTGATATCTGCAACCGAAACTACGTACAATCGCTGCCGGAGGAGCAGGCGGCCTACGGTCCTTCGATGGCCGCTGCGCGAACAACGACGGGCGCCGTGTCGGATGGGACCTCGGCCATGCCCTTCCCATCGGCTTCCGAGCTGTCGAACGAAAGTGTGAGCGATGCGAGCGTCAGCGTCAACGTGCGATCGATTGTGGACAGCCCGATGGAACAGCATGACCTCAGCAGTATCGATCCGTTCGGGTCCGACAGCGAATGTCTGGGTCAGTTCTTTGCTACCGACGCCACCTCCAGCTCGCCCAGCACggccagcaccaccaacaacgcGCAGGCAGTACCAAACAGTGCCAACGTCGGGAGTCTGCTtcccaacaccaacaccaacaccaacaccaacacgctACACCAACCGGAGTCGGCCAAAACGTACTTTGTGCTCGGAAATGTGGAGCAGTTGCAACAGTTTCACGCAGCGGTAGcgatacaacaacaacagcaacaacaacaacaacaacagcagcatcccaGCAACAATCCACCGCCGGCCACCAATAGCttccatcatcttcatctgccaccacccgggccggggtcccatcagcagcagctatCACTCTCGCTGCAGAACGCGGCCCCGATCACGGCGGGCTCGCAGCTTCTGCCCAGCGAGCACGAGGTCACTAGCTTGCAGCAGTACGATCAGTACGACGATGAGGACTACTCGTCCATGTCCGAAGATGAAGCTATTGTTCCAATAGAGCCGTATGCCAAGTCGCCCAACCAGGACCACGCCAAGACGGAGCTGCCCATCCAGGAGACAATCGTcgacaccagcaccggcggcaccggcagtgTCGTTTCGCTGCCCCAATTCGCGGCGTCTGGCACGGTGCCAAGAGACGACGCCGCGCTGGGCCGCTTGCTGATGGCGCACGGTGTTGTGCACCCGCATCTgcaccatcaacaccagcagcaacagcagcagcagcagcagcagcagcagcaacagtaccATCACCAATCGCCTGAGGTTTCGACCCCCGTTTCGACACACCTCgcggacgacgatgatgaaggGAAATGTGATTCGTCATCGTCGCTCGGCACGTTTGTCGGCGGTTCGTCGGACCGAGCGAGGGTCGAGGAAGGCCGTCCGGTGCCACCGGCACGCTGCACCTCCCTCGCCGACGGTTCCAGCATCGATCGGCCGTACAAGTGTCACATCTGCGAGCGATCGTACCGCAATCAGAAGAACCTCAAGTCCCACCTCAAAGTGCACGAGGGCATTCGGGCGTACCAGTGCGAGATCTGCGGTAAGAATTTCTCCGGCTCCAGCTACCTGGTGatccaccggcggcggcacacCGGCGAGCGACCGTTCAAGTGCGCCACGTGCGGTAAGGCGTTTGTCGACTCGCGCGCACTCGCCGTCCACGCGCGGCTGCACAGCGGCGAACGGTTGAAGTGCGAAAAGTGTGAGAAAACTTTCTCGAGCGTGAGCGCCCTCACGGTGCACAATCGGCTGCACACCGGCATCCACCCGTACAAGTGTGAGCTGTGCGGCAAAACGTTCCCCCAGTACAACAACCTGAAGCACCACATGAAGAAGCACGAGCAGCCGAATGCGGCCGagaagcagccgcagcaggcAACGGCCGCAGCGTCCGCGACTCCACCGCTAGCGCCTGCGCTGCCCAACGGGGTCAGCACTACGAGCACTACGGGCGCCGGGATCGCTGCGGGACGCGTCGGATCGTCAGCAACGCCGACGGACGCGAAGCAGAACGGGCCGGCGCACATGGCGGCCAGCTCGACCACGGGCGCCACGTTCGAGTACAAATGTCACATCTGCAGCAAGCTGTACAAAAACGCCGACGACTTGCAGGAGCACCTCACCCAGCACAGCAAGGATCGGCCGAACCAGTGCGAGTTCTGCTCCAAGGTGTTTCCGCGTTCCTCGCACCTCATCATCCACCGGCGCCGGCACACGGGCGAGCGACCGTTCAAGTGCAAATACTGCGACAAGGCGTTCGTGGACTCGCGGGCACTGTCCGTCCACACGCGCCTGCACACGGGCGAGCGCGTGAAGTGCGAGATCTGCGAGAAAACGTTCGCCAGCTCCAGCGGGCTGATCGTGCACCGGCGCATCCACACCGGCGTGCACCCGTACAAATGCGACTACTGCGAAAAGTCGTTCGCACAGTCCACGGCCCTGAAGTACCACCTGAAGAAGCACGATACGGCGCTCCTGCCCACGACGACAACGCCCGAAACCGCGGACCCGGTGAGCTCACGGTTGCTGGCGCTGCCACAGAGCGCAAAGCAGGCCGCCGACGCCGGCCAATGCCTGTCGGTGTTCGGTGACGGTGAGTCGACCGCTACGCACGGGAACGATCGGTACAAGTGCACCGTGTGCAGCAAGATCTTCCGATCCTCCGAGTACCTGGTGCGCCATCGACGGACGCACAGCGGGGAGCGACCGTACCAGTGCGAGATCTGTGGCAAAAACTTCTCCACCATGAGCTACCTGGTGATCCACCGGCGGCGTCACACGTCCGAGCGACCGTACAAGTGTACGTCGTGCGAGAAGGCGTTTGTCGACTCGCGGGCGCTGCAGGAACACGCCCGCCTGCACACGGGCGACCGCGTGCGGTGCGAGATCTGCCAGAAGACGTACTCCAGCGTGAGCAACCTGATCGTACACCGGCGCATACACAGCGGAATCCACCCGTTCGAGTGCGACAGCTGCGGTAAATCGTTCGCGCAGAAAAACGCACTCAAGTACCATCTCaagaaacacatcaaacagAACTAA
Protein Sequence: MRFEAFGSDYAKPQLPPAVPPLPMPMAQQQAPQQQQQQQQPCKCEFCEYLQANRISLTGDHSFQCEFCGEGFANQTSFNRHRCGSTDIQIYRCENCRREYGSSRALSTIGNCEPRDKCDICNRNYVQSLPEEQAAYGPSMAAARTTTGAVSDGTSAMPFPSASELSNESVSDASVSVNVRSIVDSPMEQHDLSSIDPFGSDSECLGQFFATDATSSSPSTASTTNNAQAVPNSANVGSLLPNTNTNTNTNTLHQPESAKTYFVLGNVEQLQQFHAAVAIQQQQQQQQQQQQHPSNNPPPATNSFHHLHLPPPGPGSHQQQLSLSLQNAAPITAGSQLLPSEHEVTSLQQYDQYDDEDYSSMSEDEAIVPIEPYAKSPNQDHAKTELPIQETIVDTSTGGTGSVVSLPQFAASGTVPRDDAALGRLLMAHGVVHPHLHHQHQQQQQQQQQQQQQQYHHQSPEVSTPVSTHLADDDDEGKCDSSSSLGTFVGGSSDRARVEEGRPVPPARCTSLADGSSIDRPYKCHICERSYRNQKNLKSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCATCGKAFVDSRALAVHARLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYKCELCGKTFPQYNNLKHHMKKHEQPNAAEKQPQQATAAASATPPLAPALPNGVSTTSTTGAGIAAGRVGSSATPTDAKQNGPAHMAASSTTGATFEYKCHICSKLYKNADDLQEHLTQHSKDRPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGVHPYKCDYCEKSFAQSTALKYHLKKHDTALLPTTTTPETADPVSSRLLALPQSAKQAADAGQCLSVFGDGESTATHGNDRYKCTVCSKIFRSSEYLVRHRRTHSGERPYQCEICGKNFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVRCEICQKTYSSVSNLIVHRRIHSGIHPFECDSCGKSFAQKNALKYHLKKHIKQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -