Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:54745-58375[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0071 0.42 10.4 1.5 1 23 485 507 485 507 0.98

2 7 0.0079 0.47 10.3 0.5 2 23 922 945 921 945 0.91

3 7 4.2e-06 0.00025 20.6 2.9 1 23 951 973 951 973 0.98

4 7 2.8e-05 0.0016 18.0 3.8 1 23 979 1002 979 1002 0.96

5 7 1.6e-05 0.00093 18.8 3.5 1 23 1008 1030 1008 1030 0.98

6 7 8.7e-06 0.00052 19.6 1.2 1 23 1036 1058 1036 1058 0.98

7 7 0.041 2.4 8.0 8.4 1 23 1064 1086 1064 1086 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0071	0.42	10.4	1.5	1	23	485	507	485	507	0.98
2	7	0.0079	0.47	10.3	0.5	2	23	922	945	921	945	0.91
3	7	4.2e-06	0.00025	20.6	2.9	1	23	951	973	951	973	0.98
4	7	2.8e-05	0.0016	18.0	3.8	1	23	979	1002	979	1002	0.96
5	7	1.6e-05	0.00093	18.8	3.5	1	23	1008	1030	1008	1030	0.98
6	7	8.7e-06	0.00052	19.6	1.2	1	23	1036	1058	1036	1058	0.98
7	7	0.041	2.4	8.0	8.4	1	23	1064	1086	1064	1086	0.98

Sequence Information

Coding Sequence: ATGATGGCCTCGTCTTTGCACCACGGAAACATGGATCACCTAGAGCACCAGGACGAGCATGAGCTCCAGATGAACCTTTCGAAAGAACTGCTTCGCAGCGGGATCGCATCCGTTGAAAGTAGTGCGATCCAGTTTATAGCATCAGCGCCCGTCGGCAACCACACGCGGGAGCAGGAATACATCGAATCGAGTCTACTCGGGACTGACCTCCTGTCCAGCCACCTTCCGACGCATACGCTGAACGATTATATCACCTCCGTACCCTGCAGCAGCACTAGCAGTCTAAACAGTTTACAGCCCACCATGCTGGAGCACCACTACCGTACGTTTCTATCGGATGACCTACAATCACTTGTCGAAGTGAGCGGAATCCAACCGTCCTCCGATCCAGCGGATAGAAAATTGTTCCAACAATATGGCAACAAGTCTTCGACCAACACGTTGGGATCAAGTAATGAGACGGCAGTGATTGTAACCGGATCAAAGGAAATACCTTCCTTCGGGACAATCACGACGTACGATAAATTGTTAAATATGGCGCAACCACCTTCTCCCATCCCTGGCGGACTAGTACAAATAAGTGGTGCAATTGATGGCTATGTACATTTCGCTCCTCCGGCGTGCGAGACGTACGACATGATAGGGAGCTCTATTACTACCAGCCACCATCATCAGGAACAGCACGATATACACAATCCTTATGGCCTtcatcatctacatcatcacactcagcatcatcatcaCCAACAACAGCAACAGCATACCCAGAATGCCAAGGAGCTTCCAGTTATGGTAAACACTTCTATAGCTTTAGGTCCAACATTCATTCCCTGCAGTCAAAGCTCGCTACAGCCATCAGATGCTAACACAATGAAGCTGCTAAGCAATACAATCATTCCTGTCACAACGATGGCTGAACCGACTCATATACATGACGGCACAACACTGACGATATCTCCATTGCGGAGTCAACCGGAACACAGTAAAAGTTACTACTCCAGCCCGCACCTTACATCATTTCTGACCAATAACAAAGAACGTTCCAATGTGACGCTTGTCGACGCAACAGTGCTCAATGATATCGGATCTGAAGTGAGTGATGCTGAAGCTCGAATAGAAGAAGCTGATACCGATTGCTTAACATCGATGGACATCGCGTCTCAGACGATGCCCCTAGCACCACAAGAAAGCATTAATCTGCCTCATAAAAAACGGTTGTCTAAAAAACTCGGCGATACTAAGGAAGCGTCGAGTAGTGGCGAATCTATTCAACCCACCAGTGTCTCAAACGAAACGAGAGTCACCGTGATTGCGAGTGAGCCAACGGTAATGTCCGATGATGCGTCTCAGCAGCCTTCTATTCTGCAATCCGGCAGGATCCAACCTGACGACAGTCACACGACGAAATCGAATGAATCGCTACCACGACAAGAACCTGCAACCATCGTTTGCTTTTCCTGTCAACTGTGCGGACAATTGTTTCAAGATCAGTTACTGTTTTTCACGCATCTAAAAACACATTACGAACCGGAGATCGTCGGTCCCAAGAAGGATACTGCCGCGGGGAAGGGAATCACAGTGAATAGCTCAAACGATCTGGCCGAGAGCATTGATGCATCGCAATTGGAGGGCAAAAAACCTAAACCGAAGTTGCCTCGTGTTAAGCACACGAAAATGCTGAAAACTGATCGTATGTTCAAAGACTCCACTGCAGGTGTTCCAACGCAGCAGAACTGCGAAGGTGAGAACAGTGTTACATCGAGCCAGATACAGACGAAACCAGTTTTAAGTTGTACGCAAAGTGCTTCCATCAATAGTAATGGTATCGAGCTAGATTCTGGTGAGTTTAGCGATACTGAGGATATGCTCGAAGGCATACGGAATGTTGTACAGCAAACGGTCGATAAGGATCCAACTGAAGAATCATGCTTTAATATAGAGCCGAAACAATGGTTTACTTCTTCGGTCACGGAGAATGCTGAGGGTATTAGCGAAAAGGAAAAAATGCTCGTTCCAAGTACGGTTGAAGGAACGGCCACGTTGCAAAGTCGTAATGCCAGTACAAATCAGAGTGCGAGCGCTTCTTCGTTCGACATGCTTTTCAACAAATCACAACTAGACAAAGGTGGACTCGTAGAGACTCTGGAAACAACGGACTATCAGTCATTGCAAACGACGCCTGTGGTCGAACTACAACAATCGAACAAATGCGACTTCCAATTGGAGCCAATTGGAGCCAAATGGCTTATGAATAACGGGGTCAAGACAGTGGCTACGGATTCCCCAGCATTCTTAGCGTATACTCAGAGCCTTATGCCATCGATGGAGCAGATAACCGAATCGTTTTCTAAAATTCAGGAAGTGGTGTCGAATCACACCGATCCATCTCAAGTTGCTTCCATCCGTTGCATCCCTTTGCCCAATTTAAGGAACTCGGTAGAAAGTCAAGACGAAGGCAGTGCTCAATCCATGTATACGAGTGCCACACCTGCCGCAGATGGCGAAGAGGAACAAACTGCAATTTCGATGGATGCTCCTCTAGACGACACTATGGAAGAGGATGGTTATGAAGATGGTGAATGCGACAGTGAAGAATTGGATAATCTATCAGCTACCGAACCCGAACCAGTGCTTGACCAGACTGAAGATAATGTAAAACAATCGAATAAGAGAAGCACAAAAGGGAAACGGAAAAGCCGTAAAGTACAACCGGGTGGCAAGAGTGGCACTACTGGCAACAACCAGTCGAAATCGACCAAATATCTCTGCCAAGTGGATGGATGCGGACGACAGTTCAACTCTAACACGGCCTTCCAGTATCACCGTTTACAGCACACTGGCGAGCGGCCCTATAAATGTGCTGTTTGTGGAAAATGTTTCATCACCTGTAGCGCTCTGAAGGTTCACGAACGGTTGCATTCTGGGGAAAAGCCATACAAATGCGATCAATGTGGCCATTGCTTCCGGCAGTGGGGTGACTTGAAGTATCACAAAATTTCGATCCACTCGAACGAGAAAAGCCACAAGTGTGAATTCTGTGGGAAACAGTTTGCTCGCCGTTATTCCCTTTCCCTGCATCGgcggattcatacgaacgagaaaaacttcatttgcgagtactgcaataaagcgtttcgggcgagcacgtacctgcagacgcatcggagaatacatacgggcgaaaagccacaccaatgtacgatatgtAATAAGAAATTCCGCTGCCACGGTGACATTAATAGGCATTTAAAAACACACGAGCGCACCAAGGATAAAGGCAAACAGCAAGCACAACCGAACGCTGATACGGATGGTGCACCGAAAGTGTCTCAAACACAGAAGCGTTCAAATGTAATTGATTTGACTAAATCAAAACCGAAAAGAGCTAAGAAGACGGCGGCGAAAGCCACCGCACTCGAGTAA
Protein Sequence: MMASSLHHGNMDHLEHQDEHELQMNLSKELLRSGIASVESSAIQFIASAPVGNHTREQEYIESSLLGTDLLSSHLPTHTLNDYITSVPCSSTSSLNSLQPTMLEHHYRTFLSDDLQSLVEVSGIQPSSDPADRKLFQQYGNKSSTNTLGSSNETAVIVTGSKEIPSFGTITTYDKLLNMAQPPSPIPGGLVQISGAIDGYVHFAPPACETYDMIGSSITTSHHHQEQHDIHNPYGLHHLHHHTQHHHHQQQQQHTQNAKELPVMVNTSIALGPTFIPCSQSSLQPSDANTMKLLSNTIIPVTTMAEPTHIHDGTTLTISPLRSQPEHSKSYYSSPHLTSFLTNNKERSNVTLVDATVLNDIGSEVSDAEARIEEADTDCLTSMDIASQTMPLAPQESINLPHKKRLSKKLGDTKEASSSGESIQPTSVSNETRVTVIASEPTVMSDDASQQPSILQSGRIQPDDSHTTKSNESLPRQEPATIVCFSCQLCGQLFQDQLLFFTHLKTHYEPEIVGPKKDTAAGKGITVNSSNDLAESIDASQLEGKKPKPKLPRVKHTKMLKTDRMFKDSTAGVPTQQNCEGENSVTSSQIQTKPVLSCTQSASINSNGIELDSGEFSDTEDMLEGIRNVVQQTVDKDPTEESCFNIEPKQWFTSSVTENAEGISEKEKMLVPSTVEGTATLQSRNASTNQSASASSFDMLFNKSQLDKGGLVETLETTDYQSLQTTPVVELQQSNKCDFQLEPIGAKWLMNNGVKTVATDSPAFLAYTQSLMPSMEQITESFSKIQEVVSNHTDPSQVASIRCIPLPNLRNSVESQDEGSAQSMYTSATPAADGEEEQTAISMDAPLDDTMEEDGYEDGECDSEELDNLSATEPEPVLDQTEDNVKQSNKRSTKGKRKSRKVQPGGKSGTTGNNQSKSTKYLCQVDGCGRQFNSNTAFQYHRLQHTGERPYKCAVCGKCFITCSALKVHERLHSGEKPYKCDQCGHCFRQWGDLKYHKISIHSNEKSHKCEFCGKQFARRYSLSLHRRIHTNEKNFICEYCNKAFRASTYLQTHRRIHTGEKPHQCTICNKKFRCHGDINRHLKTHERTKDKGKQQAQPNADTDGAPKVSQTQKRSNVIDLTKSKPKRAKKTAAKATALE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092482; iTF_00093094;
90% Identity: -
80% Identity: -