Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:39937-43288[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3.7 2.2e+02 1.9 0.2 1 10 51 60 51 66 0.83

2 12 7.4e-05 0.0044 16.7 1.3 2 23 391 412 390 412 0.97

3 12 1.7e-06 9.8e-05 21.9 0.4 2 23 419 440 418 440 0.97

4 12 0.15 8.6 6.3 0.8 1 23 450 472 450 472 0.90

5 12 1.4 84 3.2 0.0 3 22 497 522 495 524 0.80

6 12 0.0011 0.066 13.0 1.6 3 23 592 613 590 613 0.95

7 12 0.0018 0.11 12.3 1.3 3 23 620 640 618 640 0.92

8 12 1.2e-05 0.00069 19.2 1.4 1 23 645 667 645 667 0.92

9 12 0.0031 0.18 11.6 0.2 2 23 676 698 675 698 0.97

10 12 9.9e-05 0.0059 16.3 1.4 2 21 705 724 704 725 0.94

11 12 3.4e-05 0.002 17.7 0.4 1 23 736 758 736 758 0.99

12 12 0.00036 0.022 14.5 2.6 1 23 764 787 764 787 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3.7	2.2e+02	1.9	0.2	1	10	51	60	51	66	0.83
2	12	7.4e-05	0.0044	16.7	1.3	2	23	391	412	390	412	0.97
3	12	1.7e-06	9.8e-05	21.9	0.4	2	23	419	440	418	440	0.97
4	12	0.15	8.6	6.3	0.8	1	23	450	472	450	472	0.90
5	12	1.4	84	3.2	0.0	3	22	497	522	495	524	0.80
6	12	0.0011	0.066	13.0	1.6	3	23	592	613	590	613	0.95
7	12	0.0018	0.11	12.3	1.3	3	23	620	640	618	640	0.92
8	12	1.2e-05	0.00069	19.2	1.4	1	23	645	667	645	667	0.92
9	12	0.0031	0.18	11.6	0.2	2	23	676	698	675	698	0.97
10	12	9.9e-05	0.0059	16.3	1.4	2	21	705	724	704	725	0.94
11	12	3.4e-05	0.002	17.7	0.4	1	23	736	758	736	758	0.99
12	12	0.00036	0.022	14.5	2.6	1	23	764	787	764	787	0.98

Sequence Information

Coding Sequence: ATGGTTAAAGCGGAAAATTGCGCGTTGTGCCTCTCGAACGAATCGGAATGGCTGCTGGAACTGTTCGGCGACGATGAACAAGTGAAGGATCGGCTACTCGTTATTTCCAAACACCTCTGGTTCGATCTGAAACCTCAGGACGATGAAACGTACGTGTGCGCCGACTGCTGGAAGAGTGTCCACGACTTCGATCTATTCTACTGTAAACTGGAAAAGATACACCGGGAGTTGCAGGAACACGACGATGATGAGGATCCGGCAGCCGTCACGACACCCCTTCCTCAACCTGATTTTGAATTTCATCCCGTGCTAGAGATCAAGATCGAACCGGATCATGATCCAGGTGCGGAGTCACCGAACGAGATGATTGAAATCATCGAAGAACATGAACATCTTTCACCGAATACTACCGTTCAGGAATCGGAAGAGGAACACAAGGGTTCAAAAGTGAAACCAGAACGTCCCCGACGAAGCGCTTCCCTGAAAACCAAATACGAATCTTCCATTTCGGAATGGGAAGCGGTCGAGCACGATTTTCTGGCAGATGACGATTATATAGAAGAGGAGAATGTTAATGAAGAGGATGCCGCggatggggatgaggatgaggatgtcgatggcgatcaggaaggagatggtgatgaggacgatgatgaACTGTATGAGGAAGAGGATGACGGAGGTGAAGATTACATCAACTATGATGAGCTTCATCGTGGTAAAGAACAGGCATCGGATAAGAATCAGTCCTCCACGAAATCGGACGTGGAAGCTAGTGACGCCCTAAGCCAAGATGTGTTGGACGTGGAACCACCGAAGCGAAAACGGGGACGACCCCCCAAACGGAAACCAGAAGACAGTACCTATGAACCGGGACCAAGTCGTGCCGATTTAAAGCGCCAATCAACGACCAGAAGTAAAAGGACTCGGAAATCTACTAATTCTGCCACGTACAGTGACTCCGACTCGGACATGATGTCCGATCCAGATGATAGCCCACGATCGAGAGCAAGAAAGAAAAAGATCGGTAACCGGCGGGCACTGGATCAGAAAATCTTTTCATATATTGATGAGTTCTTCTGCTACTACTGCCCGGACAAGGTGCTTTTCGAGCGGTTCCATCATGCCAACCTGCACTACAAGGAACTACACAATGAACCGGCCTTCCTGCGGTGTCCAAAGTGTGGCAAAAAGTGCTTCACTCCCGGTGGCTTCTTGAGCCACATGGAAACGCATGACGATCCGGAAAAGAACAAATGTCCAATCTGTGGGAAGGTGACGGATCAACGAATCACGCTAAAGAAGCACATGCGTGCTCATCAGCAGAAGCTAGAGGAAGCACTACCGTACCCTTGCAGACAGTGCCCCCGGCGGTTCGATCAGGAAAAGGTTCGAGATAAGCACGAGCGCTTGCATGGGCGGAAGATCGTGATCCGCAAAGAGAAGGGGCGAGATCTGGAGTTGCTGGCATTCTACAAACGCATCTATTGTGAAATTTGTGAAGAAGCGAAGCCCAATTCAACCTCCTTCGACAACTTTTGGGATCTGAAGGTGCACATGGGCGACGAGCACAACAGAAACCCTTATCTAAAGTGTCATCTATGCCTGGCAAAGCTGCCATGCCGGCAACAGCTCATGATTCATGTCGATGTGCATAACAATCCGGAAAATTATCGGTGCGAAGTATGTAGTGAAATTCACCAGAATCTCGAGAAACACATGATCAAGGCACACACACCGGAAACATCCTTACCACCGGAGAAGAACTATGGCTGCGAGCAATGTGGGAAGATGTTTAAATGCGAAACGAACTTGAAGAACCACATCGATCGTGTGCACGGCGTAAAGGACGTTTGCTGCGACATATGCAACAAATCCTTCAACCGAAAGGCCCTCGGCGCACACAAGCGATCGGCCCACAACGACGAGATGTACATGTGCGAGCACTGTCCCAAAATGTTCAAGACACGCAGCGGCCTCGAGTCGCACAAAGGCGAGCACGATGCAAACCTGCGCAAATCGGTCAAGTGTGAACTATGCGGAAAGGAGATGCGCCGTGGAGCCAGCATGGCGAAACACATGAAAACGATCCACTCGCAGGAGGACCCCGTCAAGTGCGATCTCTGCGATAAAGTGTTCCGCACCTCCTTCCACATGTTGCGCCATCGGCAAAACACTTGCGCAGCGACTATCAACTCGCGCCCGTACAAATGCGAAGTTTGTGGCAAAGGCTTCGCAATGAAGCTCACGATGACGGAACACATGACGACGCATACGCGCACCAGTCTGTATCAGTGCGCGTTTTGCTTCAAGACGTTCGGTTATATCTCGAACCTGTACAAACACCGTAAGAAGGCTCATCCGGCGGAGTGGCAGGAGGTCCAGGCTCGCCCAGAGGACGGCATTGCGACCGTGATCGAAATAAGAAACTGA
Protein Sequence: MVKAENCALCLSNESEWLLELFGDDEQVKDRLLVISKHLWFDLKPQDDETYVCADCWKSVHDFDLFYCKLEKIHRELQEHDDDEDPAAVTTPLPQPDFEFHPVLEIKIEPDHDPGAESPNEMIEIIEEHEHLSPNTTVQESEEEHKGSKVKPERPRRSASLKTKYESSISEWEAVEHDFLADDDYIEEENVNEEDAADGDEDEDVDGDQEGDGDEDDDELYEEEDDGGEDYINYDELHRGKEQASDKNQSSTKSDVEASDALSQDVLDVEPPKRKRGRPPKRKPEDSTYEPGPSRADLKRQSTTRSKRTRKSTNSATYSDSDSDMMSDPDDSPRSRARKKKIGNRRALDQKIFSYIDEFFCYYCPDKVLFERFHHANLHYKELHNEPAFLRCPKCGKKCFTPGGFLSHMETHDDPEKNKCPICGKVTDQRITLKKHMRAHQQKLEEALPYPCRQCPRRFDQEKVRDKHERLHGRKIVIRKEKGRDLELLAFYKRIYCEICEEAKPNSTSFDNFWDLKVHMGDEHNRNPYLKCHLCLAKLPCRQQLMIHVDVHNNPENYRCEVCSEIHQNLEKHMIKAHTPETSLPPEKNYGCEQCGKMFKCETNLKNHIDRVHGVKDVCCDICNKSFNRKALGAHKRSAHNDEMYMCEHCPKMFKTRSGLESHKGEHDANLRKSVKCELCGKEMRRGASMAKHMKTIHSQEDPVKCDLCDKVFRTSFHMLRHRQNTCAATINSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPAEWQEVQARPEDGIATVIEIRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092368; iTF_00092985;
90% Identity: -
80% Identity: -