Adar006147.1
Basic Information
- Insect
- Anopheles darlingi
- Gene Symbol
- -
- Assembly
- GCA_000211455.3
- Location
- scaffold:69347-72698[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.19 11 5.9 0.1 2 23 266 290 265 290 0.92 2 12 7.8e-05 0.0046 16.6 1.0 3 23 299 319 299 319 0.99 3 12 2 1.2e+02 2.7 0.8 10 23 374 388 372 388 0.87 4 12 0.0022 0.13 12.0 0.6 2 23 396 417 395 417 0.98 5 12 0.072 4.3 7.3 0.3 10 23 506 520 503 520 0.91 6 12 0.00026 0.015 14.9 1.8 2 23 528 549 527 549 0.96 7 12 2.9e-06 0.00017 21.1 0.5 1 23 580 603 580 603 0.95 8 12 0.035 2.1 8.2 0.2 3 23 610 630 608 630 0.87 9 12 9.3e-07 5.5e-05 22.6 0.3 2 23 635 656 634 656 0.95 10 12 0.00043 0.025 14.3 0.6 2 23 719 741 718 741 0.96 11 12 2.6e-05 0.0015 18.1 2.3 2 20 748 766 747 768 0.94 12 12 0.00011 0.0063 16.2 1.1 1 23 775 798 775 798 0.94
Sequence Information
- Coding Sequence
- atggaggctgaagtgcagcagcagcaaccgcaggatgtttacatccaccaccaccacccgacgacggccatcatcgatGATCGGCAGGAGTGCGAAGTGTGTCTTACGTATCGTGTGGGCGACATCCTGCTGGACATCTTTGAGCCCCGGGAGGACTCCGACAAGGAGACGACGTACCTTGTGTGGAAACATGTCGGTCTCCAGTTTACGCAGTGCGCCCGGAAGCAGTTCATTTGCTACGACTGCTGGAAGGCGCTCCAGGAGTTTAACCGTTTCTACATGATGGTGCAGGACGTGCACACGAAACGGGCCGAACAGCTGGCGACGATGAAGCAGGAACCGGTGGAAGAATCACCGGAGGAGCAGCAGCAGCAGATTCAACACCACTATCAGCAACCCTCGTCTGCGGAACCCGTAGAGAATGGTGTGAACGGGAGCGAATACGTAGCGCACTGTGCTTCCGGAGCACCCGTTGCCATGGCAGACTGCTATGCACCACCACCGTCTTCATCGTTGGCGACCGCTGGTCTAAGTGAGCCACAGAACGGTGTGAAGGAAGAGTTTTGCCAGCCCAGGGCCGGTGGATCAAGCGAGCTGCTACTGAACAACGGTATCATGGCAACGGGTGACGAGATGCAGGCAGGCCGTGCTGCTGGTAGTGCTGGTATGGTGGAACTACCGGAAGGTAGTGGACTGGTGCAGCGAGCCGGTCCCGGTGGTGTACCCGGTACACCGAGCCGGAAGCGCAAGAACCAAGATATGGACGACGAGATACTGGACTTTTACAAGCAGCTCGTGTGCGACGTATGCGACGATCGCACCGAGTACGGTACGATGAAGGAGCTGAACCAACACATGAGGCTAGCCCACGGTGAAGATTCGGGTCGTGTCGGGTGTCCGCAGTGTGGCAAACAGTTCCGTACGAGGGTGAAACTGCTCGAGCACAAGCAGATGCACGATCATCATCCGGCGACACCGACGGTTGGCGGTGAGACGGACGCCGAGAAGCTGCAGTCGGCTCAAATGGACCAGGAGATACTGGAGTTCTATAAGCGTATCGTGTGTGATGTGTGTGATGGTGGGGCCGGGAACGGCGGCTCCTCGACACCCTGTACACTGTATAGCACAGTGAGGGAGCTGAACCACCATATGCGATTAGTGCATGGACAGCAGGCCGGTACGGTCAAGTGTCCGCTGTGCGAGAAGAAAATCCGAACCCGCCCGAAGCTGCTCGAGCACAAGCGGATGCACCTGCCCGGTACGTTCGTCACCGAGGACGATCCATCCGGGGCGAATCGACCGCTCGATTTCGGTAGCGCtggtagtggtggtggtggcggtgttggtggtggaggtggtggtggtggacccggtagtggtgCTGAGCTATCCGAGGAGCAGTCGTTCGATATGGAAATATTCGATTTCTACAAACCGATCGTCTGCGAAATCTGCGATTCGGAGCGGCTGATGGTCAGCGGTGAGGGTGGTGGTGGTGGTACGGTGGATGCGGAGTACCGTACGTTAAGGCAGCTGAATCAACATATGCGCACGTCGCACGGCCAAGAGTCAGGCACGATCAAGTGTAAGCTCTGCTCGAAGAAGTTCCGGACTCGTGTCAAACTGATCGAGCACAAGGAGATGCACCAGAACCCGGACCGGTTTCGGTGTACCGTGTGCCAGGAGGTGCACCAGAACCTCGAGGAGCACATGCAGAACAAGCACCAGGATTGGGCGTTCTCGTGCGAGGAATGCGGTAAACGGTTTCCCTTCAAGAGCCGCCTCACGGCCCACATGGGCAAGGTGCATCAGAAGAAGGACATCATTTGCGAAGAGTGCAACAAACCGTTCACCAAGCTAACGATCGAGAAGCATAAGCGGGCCGTGCACGGTGCGATCCTGATGTGCGAGAACTGTCCGAAAACCTTCAAAACACGCGCCtctctcgaacgccacatggagggccacaatggtgctggtgatcagctgctgcagcaacagcagcaggagcaacatcagcaacagcaacagcagcagcaccagcatcagcagcagcatccgcagcaacagcaatcgcaaccacagcagcaaGGATCGACTACTCCTATGGTGGTAGCAGCGTCTGCGGGCACCGTTTCCGTAGCCGGTACGGTTAGCTGTACACTGTGCAACTCGGTTCTTAAGGACGAGTacaatctgaagacccacatgaagcggatccacgccgagcaaacgccctcgacgtgcaaaacgtgcggtaaaacgttcaaatcgaagcacagcctctacacgcacatctcgaacgtttgcaccacacgccagtttccctgcacgatctgtgcgaaacagttcaagaagcggacaaagctgaaacaacacatgaccgctgcccatggccggagCGCCGATTAG
- Protein Sequence
- MEAEVQQQQPQDVYIHHHHPTTAIIDDRQECEVCLTYRVGDILLDIFEPREDSDKETTYLVWKHVGLQFTQCARKQFICYDCWKALQEFNRFYMMVQDVHTKRAEQLATMKQEPVEESPEEQQQQIQHHYQQPSSAEPVENGVNGSEYVAHCASGAPVAMADCYAPPPSSSLATAGLSEPQNGVKEEFCQPRAGGSSELLLNNGIMATGDEMQAGRAAGSAGMVELPEGSGLVQRAGPGGVPGTPSRKRKNQDMDDEILDFYKQLVCDVCDDRTEYGTMKELNQHMRLAHGEDSGRVGCPQCGKQFRTRVKLLEHKQMHDHHPATPTVGGETDAEKLQSAQMDQEILEFYKRIVCDVCDGGAGNGGSSTPCTLYSTVRELNHHMRLVHGQQAGTVKCPLCEKKIRTRPKLLEHKRMHLPGTFVTEDDPSGANRPLDFGSAGSGGGGGVGGGGGGGGPGSGAELSEEQSFDMEIFDFYKPIVCEICDSERLMVSGEGGGGGTVDAEYRTLRQLNQHMRTSHGQESGTIKCKLCSKKFRTRVKLIEHKEMHQNPDRFRCTVCQEVHQNLEEHMQNKHQDWAFSCEECGKRFPFKSRLTAHMGKVHQKKDIICEECNKPFTKLTIEKHKRAVHGAILMCENCPKTFKTRASLERHMEGHNGAGDQLLQQQQQEQHQQQQQQQHQHQQQHPQQQQSQPQQQGSTTPMVVAASAGTVSVAGTVSCTLCNSVLKDEYNLKTHMKRIHAEQTPSTCKTCGKTFKSKHSLYTHISNVCTTRQFPCTICAKQFKKRTKLKQHMTAAHGRSAD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092365; iTF_00093005;
- 90% Identity
- -
- 80% Identity
- -