Basic Information

Insect: Anopheles darlingi
Gene Symbol: ZNF275
Assembly: GCA_000211455.3
Location: scaffold:175636-177772[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.5 1.5e+02 2.4 0.5 3 23 156 177 155 177 0.89

2 14 0.00036 0.021 14.5 0.4 2 20 190 208 189 210 0.92

3 14 0.1 6.2 6.8 0.2 1 20 218 237 218 239 0.94

4 14 0.16 9.3 6.2 1.2 2 23 303 325 302 325 0.93

5 14 0.00077 0.046 13.5 0.1 2 20 341 359 340 359 0.96

6 14 0.01 0.61 9.9 1.4 1 19 369 387 369 389 0.96

7 14 4.7 2.8e+02 1.6 2.7 3 23 432 454 431 454 0.85

8 14 0.00057 0.034 13.9 0.5 1 21 470 490 470 491 0.95

9 14 8.1e-06 0.00048 19.7 0.2 3 23 500 521 499 521 0.96

10 14 4.2e-06 0.00025 20.6 0.8 1 23 528 550 528 550 0.98

11 14 0.00061 0.036 13.8 5.2 1 23 556 579 556 579 0.98

12 14 0.00027 0.016 14.9 0.5 1 23 585 607 585 607 0.99

13 14 0.0017 0.1 12.4 0.7 3 23 615 637 613 637 0.92

14 14 0.048 2.8 7.8 4.5 1 21 643 663 643 668 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.5	1.5e+02	2.4	0.5	3	23	156	177	155	177	0.89
2	14	0.00036	0.021	14.5	0.4	2	20	190	208	189	210	0.92
3	14	0.1	6.2	6.8	0.2	1	20	218	237	218	239	0.94
4	14	0.16	9.3	6.2	1.2	2	23	303	325	302	325	0.93
5	14	0.00077	0.046	13.5	0.1	2	20	341	359	340	359	0.96
6	14	0.01	0.61	9.9	1.4	1	19	369	387	369	389	0.96
7	14	4.7	2.8e+02	1.6	2.7	3	23	432	454	431	454	0.85
8	14	0.00057	0.034	13.9	0.5	1	21	470	490	470	491	0.95
9	14	8.1e-06	0.00048	19.7	0.2	3	23	500	521	499	521	0.96
10	14	4.2e-06	0.00025	20.6	0.8	1	23	528	550	528	550	0.98
11	14	0.00061	0.036	13.8	5.2	1	23	556	579	556	579	0.98
12	14	0.00027	0.016	14.9	0.5	1	23	585	607	585	607	0.99
13	14	0.0017	0.1	12.4	0.7	3	23	615	637	613	637	0.92
14	14	0.048	2.8	7.8	4.5	1	21	643	663	643	668	0.91

Sequence Information

Coding Sequence: ATGAGCGTAAAGTGCCTGCTCTGCACGGAATTCATCGCAGCCAAACAGGCGATAAGTCTGCAGGATCAATTCGGCGATGCTTCCGTTGCTGAGGCCTTGGCCACATTCGTAAACATGGAGATAGTAATAGGAAACTATTTTCTCTGCTTAAACGTGTGCTACAAGCGATTGGTGGATGGAGTGGATTTGCAAAAATCTATAAAAGCGGTCTTTGAACAAATCTCGCTACAAGCCGGACCGTTTCTGTTGGAAACGATGAGTGAGGACGTCGGATTTGATGCCAAGCAAGATGCGACAAAAACCACAATGGAAAAGTCTTTGCTCGACATTGAAATACTGCCCGGAAAAGCAAACCCTCCGACACCCTCAGACAGCGGGGAAGCTTTCGTTCCGCCTGACCAAAGCCTTATCATGACTCATATGAAGTTTAATAATTTTGATTACCTGGAGCTGAGCGGCAGAAATTGCTGTGGCTGTGAGTTTATGTCTTCAAGCCTAAAAGAATTGGCACTACATGGGCAGGAAGTTCACAATCGTCAGTCCACCGAACAGGACAATGAAGCCATCGTTTGCACCATCTGTAGGCGACGGTTCAATAACAGAGAGCAGCTGCAATCGCACAATAACCGACCTCCCATTGTGAGGGAAGTTTTTGTCTGTAAAAGCTGCATGAACGGTTTTGGAACAAAAGAAAGTTTAACTAATCACATGACGCTATGCCCTTCCAAGTATCGAGATGAAAGCCGAGATAAAATCGTAACTATCGCTGATTACGATGACGATGAGTTGGAGATGGCAGACTTGAACGATGCACAAATTGGAAGGCCAATTCAACCACTGGATGGTAAATTTGTTACATGTCAGGAAGAGTTTGATGATTATTACATTCAGCATACCGAGGCGAAACGATGCTGCGGCTGTGGGCTTTTCTTCCAGAACGACCAAGAACTGATGGATCATGCTACCAAGGCACACCGTACTGCCCCAACAGTTGAGCCTGGTAAATTCCAAAACCGATGGTCTTGCAACGTTTGCCAGGGGGTTTTCCCATCGCAAACATCGCTCAAACGGCACATGTGGGCAAACCGGAGCATTCGGAAAATTTACCACTGTAAGCTGTGCAACCTCCCATTCATTCGGCTCTGGCATTTGGCGCAACATTTTTATGGCTCAAAAAAGCATCAAAACAGCAAATCTCCAGCAAAGGATGGAAAAACAGAGGACAATAAGATGAAGGCGATTCTGAAAAGGCTTGGCGCTTCGCGTGACAAAATGTCGACAGAGCGTGGCTGTTGCTTTCTGCGATGTAGTGCTTCGTTCGGTACGCATAAGCAGTTGCTCGATCATGTAGAGGAACAGCATGCGGTACGGCGTCGAATTCACGGCAGTGAGCGTACGTCCCACGATTTCGTGTGCGAGGTATGTCAGCTCGGGTTTTGTAAGGAAAAGAATCTGATAGCCCATCAGAATAGATTTTCCTTGAAAAAAGCAAACATTTGTACTTTCTGCGGAAAAGGCTTCAAGCACCCTAGCGGACTGGAGGAGCACATCCTTATCGAGCACAGTGACGTGcccccccGATTCGAATGTGACCAGTGTGGCAAAATATTCAAAAAGAAATCCCTCATAAAGCTGCACATGGTGACGCACCAGCGGAACCGAGAATTTACCTGTGACCAGTGCGATCGTCAATTCCATTTCCGATATCAATTGAAGCAGCATAATCGCACGGTGCACGCCACCGAGTTTCCATACGAGTGCACCTACTGTGATCGAAAGCTGCCGGACAAAGGGCGTTATGATGTGCACATGCGGAGCCATACCGGCGAGAAACCATACGGCTGCCGGTTCGAGTGTGATCGGTCCTTCACGAACTCGACGGATCGCCGCCGTCACGAGATGGTTGCGCATACCGGAGAAAGGCCTCACCACTGTCCCACTTGCAAGGTGAGCTACGCACGTCATCGAAGCTTGCAGCAGCACTTCCAGAAAAACCCCAATCATAAACTCGCACCCGCTGATCAGGAGGAACGTAAAGCGAGTAAGGAGTAA
Protein Sequence: MSVKCLLCTEFIAAKQAISLQDQFGDASVAEALATFVNMEIVIGNYFLCLNVCYKRLVDGVDLQKSIKAVFEQISLQAGPFLLETMSEDVGFDAKQDATKTTMEKSLLDIEILPGKANPPTPSDSGEAFVPPDQSLIMTHMKFNNFDYLELSGRNCCGCEFMSSSLKELALHGQEVHNRQSTEQDNEAIVCTICRRRFNNREQLQSHNNRPPIVREVFVCKSCMNGFGTKESLTNHMTLCPSKYRDESRDKIVTIADYDDDELEMADLNDAQIGRPIQPLDGKFVTCQEEFDDYYIQHTEAKRCCGCGLFFQNDQELMDHATKAHRTAPTVEPGKFQNRWSCNVCQGVFPSQTSLKRHMWANRSIRKIYHCKLCNLPFIRLWHLAQHFYGSKKHQNSKSPAKDGKTEDNKMKAILKRLGASRDKMSTERGCCFLRCSASFGTHKQLLDHVEEQHAVRRRIHGSERTSHDFVCEVCQLGFCKEKNLIAHQNRFSLKKANICTFCGKGFKHPSGLEEHILIEHSDVPPRFECDQCGKIFKKKSLIKLHMVTHQRNREFTCDQCDRQFHFRYQLKQHNRTVHATEFPYECTYCDRKLPDKGRYDVHMRSHTGEKPYGCRFECDRSFTNSTDRRRHEMVAHTGERPHHCPTCKVSYARHRSLQQHFQKNPNHKLAPADQEERKASKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -