Basic Information

Insect: Anopheles darlingi
Gene Symbol: ZFX
Assembly: GCA_000211455.3
Location: scaffold:31846-40869[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0006 0.035 13.8 1.5 1 23 1074 1097 1074 1097 0.96

2 8 0.00037 0.022 14.5 0.1 1 23 1360 1383 1360 1383 0.98

3 8 1e-05 0.00059 19.4 0.5 3 23 1391 1411 1390 1411 0.97

4 8 6.8e-05 0.004 16.8 1.1 1 23 1417 1441 1417 1441 0.99

5 8 3.5e-06 0.0002 20.9 2.5 1 23 1451 1473 1451 1473 0.96

6 8 6.4e-06 0.00038 20.0 0.3 2 23 1484 1505 1483 1505 0.96

7 8 8.1e-08 4.8e-06 26.0 0.6 1 23 1511 1533 1511 1533 0.98

8 8 0.037 2.2 8.2 1.3 2 20 1541 1559 1540 1561 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0006	0.035	13.8	1.5	1	23	1074	1097	1074	1097	0.96
2	8	0.00037	0.022	14.5	0.1	1	23	1360	1383	1360	1383	0.98
3	8	1e-05	0.00059	19.4	0.5	3	23	1391	1411	1390	1411	0.97
4	8	6.8e-05	0.004	16.8	1.1	1	23	1417	1441	1417	1441	0.99
5	8	3.5e-06	0.0002	20.9	2.5	1	23	1451	1473	1451	1473	0.96
6	8	6.4e-06	0.00038	20.0	0.3	2	23	1484	1505	1483	1505	0.96
7	8	8.1e-08	4.8e-06	26.0	0.6	1	23	1511	1533	1511	1533	0.98
8	8	0.037	2.2	8.2	1.3	2	20	1541	1559	1540	1561	0.94

Sequence Information

Coding Sequence: ATGGCGACGCTGAATTGGCGAACGCCGCAAGCACCGGCAGCAGTGGCGGCTGCTGCGGCTGCCGCAGCTTCAAAGAAACCACGCGGACGCCCCGGCATTCGCACCAAAATGGCTTACGATTACTACAACAACGGGGTAGCGGCAACAGCCGCGGCCGCAGCGGCTGCTTCTGCCATGGTAAACGTACAAGCCGGACCACAAGCCCATATCCCATCGTACATGCTGGCGAAAAATCGCATGTTCGATGCGCATGCCGCGGCTACCGTCGTGTTGCCGCCAGACTATGGGCAGAAGCTGTCGGCGGCATCATCCGCCCCGTTACAAGCGCCTCCACCACCGGCAGTGGCCCCAGCAATTCCTGATGCAAAGCACACTACTCCACAACAGGATGAAGGTGAAGACAACGATGATTTTTTGAGCGAAATCACCATTCAATTCGACGATGATGAGGTACAAACGCTGTACGTTGGACCGGTGGAGATTGTGGAAAACTCTGCGAATGGAGGGCAACGTAAAGCTGAAGACGCTATTACGGCGGGAAAATCCGTAGCACCGCTACTACCCGCCGATAGCACTAGCCCGGCCCAACGACACCGGGACCGATTCGCGGAGGAGAGAGCAATAGTGACACTTGAAACAGTCGGCGAAAAGGCAACGAGCCAACCACTGCCGATGTTTCTGAagcaacagaaacaacaaaagcaacatcagcaacatcagcaacatcagcaacatcagcaacatcggcaacagcagcaacagcagcaacagcagcaacagcagcaacagcagcaacagcagcaacatcagcaacatcagcaacagcagcaacatcagcaacatcaacaacagcagcaggaggtgcaacaaaatcaacggcaaaaacgacagcaacggcagcaacgggtacaacaacaaatggagaagcagttgcgaactcaactcgaacaacaaatgcaaaagcaacagcaacaacaacatctacagcaacagcaccaccagcaacaggcattgcttaagcagcaaactattctgcagcaaatgcagctcttgcacgattctcagcagcgccagcagcaagccaagcagcagctttctctgatcgagcagcacattaagatgagcgtccatcaacagatccatgcccagcagcagcaatttcataaacaacagcagcaattgcaacagcaacagctagagcaatttcaaaaacaacagcagcagcagcagcagcaacaacaacttcaacaacaactacaaatacagctaaggcagcaacaggagtttcaacgtcatcgcagcaaggctaaacagcagcagccgcaaccgctcgtacagttaccgattcagcagcCACTTCCGCCGTCAAAACCACAATATAGAGCACAAGCTGGCATGAAACAAACGGCATCTTCCAATGTTACTGTGATTGCCGCCGCTCCTGCTCCAATACCGGCGAAAACCATTGCCAATCACAATCCACCGGAGATGATAGTACCCAGTGTCGTCAATGGTAACGGTGGTGGCCTGCTACAACCGTCACCACGAAGTATTGCATCGCCACAACATCCGGCTTTGGACAGAGAGTTGGTCATTATTAAACAAGAACCCGTGACGGAGCCTGTGACATGCGAAGCCAGTGAGTCCGTCGTTACACCGGGCGAAACGACATTCCAGCAGCCAGCTAACGGACCGTCGTCGGAAACAACGCTCCCGGAAACAAAACCAGTACTCACACCGCAGCAACAACTAGCGCAGAAGGCTCAAAATGGTGTCGCTTCGTCCGATAGTGATCGTGGTAATCATGGTCCAGCAACACCGATATCCATCATCTCCACCACTACCTTTACCACCATTCACACCGACAAACGATCGGCGGAGCTGTTAAGCAACATCAGCGCGACGACGCTGCATGACGCTAGCGCCGGTAGCAACAGTATTGTCCGGGAAGCTGTTCCCAACAACGATGTCAACGGAACTGCTGGTACCGGGTGCCCAGTCGTGGACCGAATGGTTGTCACCGGCGTGGAAGATGGTAAACCTTTAGCTACCGTCACCAGCAAAGAGGATATCTCCAGTCTCGTCGATGCAGCAACAACTGGCACCATGCCAGCAGTAGTAGCGGCTACACCATCCCCAGTCGTGAAGCGAGGCCGTGGCCGCCCACCTAAGGTTAAGAAAGTGCAAACACCACAAATTGCGACTACGGCACCCCAGGTGATCTCCATTACTCCACAAGCAACGACGATCAGCAGCAGTTCTTTTAAGGAATCAAATTCTCAGAATGAGGCCACAACTGAGACTGACCATACCGTTGCGGTGTGTAGTGACCATCCTCCGTCCGCGGACATTGCAACCGGCAACGTTGAAAAGGAGTGCAATGGAACTGCAAAGAAGCAGAAAATTGGACGTGGGTTACGTGGTCGCGGCAAAGAAGAAGAAGATGATGAGTTGCGACCGGAAAAGACATTTATCTCGATGGTCGCACTTTGCCCACAGAAGGACCGTAAACGAGCGCGCACCAAGCCTCCTCCCGACGATACCGCAACCGTTTGCGAGCTACCGCCGACCTCGCCTGTTATCGATTGTGTTATGCCCGAACTAGCCGTTGAGGTTAACAAAAAGACTGAAAGCGACGAACCTACTACGATGATCTCGGACACTATTAGTAGTGGCGCTAGTGCTACTTCCGAACCCCTCTCTACCACATTGACGCAACCGCCGTGTCCGACAGAGAAAGAATGCGTTCAAGGAGAAATATTACAACCAGAGATTAGCCAGAAGAATTTGCCGAAATCACCAACCGCACGAGCCACTAACGATGACGTACAGCATTACGCAACGACGGTCGTCCTGTCGACCGAACCATTTTCTTCCGGGTGTGACAGTGGCATTGAATCGGCTGGTGATACGATCACGAGTAACCGTACATCCTCTGGCAAGGAGAAGGTCGCACGTATCGGCGTCATCATGGAAGCATCTGAGACAGGCACTGAAcagcagcagcagcagcagcaggtggtgcagcaagccgaacagcaggaagcagTAGTCGAAAGCGCTGAGCATGACATCGAAGGAAACACGGGCGTACCAGGACTAGCAGGCGTGGTAACTAAAGTCGAGGAAGACAGTGGACTCGAGAGAAGTCCATCGTTGGAAACAACGGAACCGAATGACGCAACGGATCTGCAAGCCGCTGAAAGCAATGAAGGAGTTTATCGGTGTAGCCACTGTGAAATGGCATTTAAAACGGAACCCTGGTACAAGAAGCATCTTTTGAATGTGCACAGCCTTGGAGAAAATGAAATTGTGCAGGAAAATGGCCACGCTGCGGACCTGCTTGCAAGTGAAGTTGCGAATGGACAGCAAGAAGTAACCACAATAGCTGCCATCGCATCGATTGACAGTGTAGTGCTTGACGTAGTGCCGCCGACCCACATTAATGACTGTATGTTGCCAGTTAACGGCGCAACGGATGCCGGATGCCATGTGGGACGAGTTCTTCGAAGTGAAACCGAGGAAAAGAACGACTTCCGAGCGGCGGTGTCATATGGAACGCGTAAGCGCAAACACACTGTATCGGGTGGTGAACCTGTCAAGCCAAATGTCGTGCCAACCGAGGATGTAATCCCCATAGCAACACTGGAAGAGGATACACCTTCAATCCCGCCTCCGAACGATCCGATCAAAACGAAAATATCGAAAATAAAGGAAGAATTTCGAGCGTCCGGCACACGCAATCGTAACAGCGTTGGGTCTGCTGCTGCCAAGATTGAAGCGCAGGAACCCATTCCGAACGATGATCCAGGGGCGGAAGACAGCATAATCAGCCCGAACGATAACGCTCTGCCAGTGGCAAAATCTTCGTCGAAAACGGCCACCAAACAATCGAAGGCACGCAAGGCATCACGTAAGAAACAAGTTGCTGCTGCTTCTCCTCCTGCTGCTCCTTCTGCTACGCCTGAGTCTATAGAGCCACTGACTGATCCCAAGGAAGAGAGCGACGATCCGAACCACCTGTCAGCGTTCGAGCTTTCCAAGTTGACCGTGGTGGAGGCGGAAGGTGGCTGTTACTACAAATGTACTATCTGCGGTGGACAGTTCAGCGATAAACCGGCGATCAAGGCGCACTTGTCGACCGTGCATGCGGCCATCAAAAAACGATCCTGCCAGTTCTGTGGCCGCTCGTTCGTGCAAACGGGCGATTTGACGCGCCACGTACGCATCCATACCGGTTTCCGTCCCTTCAAGTGTCCGTTCGTCGAATGCAGTTACGCGTTTATTTCGTCCGGCGATCTACACAAGCATGTGCGGCGTCACAATACCGACGAGCCGGTACCAAAACCCCACGTGTGCGAATACTGTGGCAAGGAGTTCGAGCGATCGTATGATCTTCGACGCCACAAGACGATGCACCTGAAGCAGGAGCCCGGTTTCAAGGGTATCTcgtgtgaggtgtgcggcaaagtgttcgcccgtaaggatcagtaccgagcgcatacctatcgtcacatcggttaccggccctacacgtgcgatgtatgtggcaagactttcacagatccgagcaacttCTCCAAGCACGCTCGATTGCACGAGATGGATGGTGTGGAGGTGGTGTGTTACTTCTGTTCACGCAAGTTTAAGAATAAGAGCGCCATCTCGAAGCACATCTTTCACTGCCAGCAGCGCATGATGGGGAAGAAGGGTGGTGGTAACCGCAGTGTGGCCGTGGCGCCTTCCTTCATCAAGGAGCTGAAGAAGGAAGCCAAGTGCGATCCGGATGACGGCGATGAGGATTACCATGCTGCTGGGTATGGTGGTCGAGGTCGAACGAATGTGGCTAAATCGCGGCCCCAACGCTCACAGCGAACACGGAAGCGACCGCTACGGATCCAGGAAGAAGACAGCAATACAGATGAGGACGAAGAAGAGGAGGATGACGATGAAGATGATGCATCGACTAGTGCCGGCAGCAGCTACCACACCTCTACCGGTTCCGGTGCCAGCGATCGTGATTCTCCGAAGGAGCCAACGAAGACGAAACGTGGACGACGCAGTGTGCGTGGTGGAGCATCAGCCAGTGCAGCCGATAGCTGCTCATCATAA
Protein Sequence: MATLNWRTPQAPAAVAAAAAAAASKKPRGRPGIRTKMAYDYYNNGVAATAAAAAAASAMVNVQAGPQAHIPSYMLAKNRMFDAHAAATVVLPPDYGQKLSAASSAPLQAPPPPAVAPAIPDAKHTTPQQDEGEDNDDFLSEITIQFDDDEVQTLYVGPVEIVENSANGGQRKAEDAITAGKSVAPLLPADSTSPAQRHRDRFAEERAIVTLETVGEKATSQPLPMFLKQQKQQKQHQQHQQHQQHQQHRQQQQQQQQQQQQQQQQQQQHQQHQQQQQHQQHQQQQQEVQQNQRQKRQQRQQRVQQQMEKQLRTQLEQQMQKQQQQQHLQQQHHQQQALLKQQTILQQMQLLHDSQQRQQQAKQQLSLIEQHIKMSVHQQIHAQQQQFHKQQQQLQQQQLEQFQKQQQQQQQQQQLQQQLQIQLRQQQEFQRHRSKAKQQQPQPLVQLPIQQPLPPSKPQYRAQAGMKQTASSNVTVIAAAPAPIPAKTIANHNPPEMIVPSVVNGNGGGLLQPSPRSIASPQHPALDRELVIIKQEPVTEPVTCEASESVVTPGETTFQQPANGPSSETTLPETKPVLTPQQQLAQKAQNGVASSDSDRGNHGPATPISIISTTTFTTIHTDKRSAELLSNISATTLHDASAGSNSIVREAVPNNDVNGTAGTGCPVVDRMVVTGVEDGKPLATVTSKEDISSLVDAATTGTMPAVVAATPSPVVKRGRGRPPKVKKVQTPQIATTAPQVISITPQATTISSSSFKESNSQNEATTETDHTVAVCSDHPPSADIATGNVEKECNGTAKKQKIGRGLRGRGKEEEDDELRPEKTFISMVALCPQKDRKRARTKPPPDDTATVCELPPTSPVIDCVMPELAVEVNKKTESDEPTTMISDTISSGASATSEPLSTTLTQPPCPTEKECVQGEILQPEISQKNLPKSPTARATNDDVQHYATTVVLSTEPFSSGCDSGIESAGDTITSNRTSSGKEKVARIGVIMEASETGTEQQQQQQQVVQQAEQQEAVVESAEHDIEGNTGVPGLAGVVTKVEEDSGLERSPSLETTEPNDATDLQAAESNEGVYRCSHCEMAFKTEPWYKKHLLNVHSLGENEIVQENGHAADLLASEVANGQQEVTTIAAIASIDSVVLDVVPPTHINDCMLPVNGATDAGCHVGRVLRSETEEKNDFRAAVSYGTRKRKHTVSGGEPVKPNVVPTEDVIPIATLEEDTPSIPPPNDPIKTKISKIKEEFRASGTRNRNSVGSAAAKIEAQEPIPNDDPGAEDSIISPNDNALPVAKSSSKTATKQSKARKASRKKQVAAASPPAAPSATPESIEPLTDPKEESDDPNHLSAFELSKLTVVEAEGGCYYKCTICGGQFSDKPAIKAHLSTVHAAIKKRSCQFCGRSFVQTGDLTRHVRIHTGFRPFKCPFVECSYAFISSGDLHKHVRRHNTDEPVPKPHVCEYCGKEFERSYDLRRHKTMHLKQEPGFKGISCEVCGKVFARKDQYRAHTYRHIGYRPYTCDVCGKTFTDPSNFSKHARLHEMDGVEVVCYFCSRKFKNKSAISKHIFHCQQRMMGKKGGGNRSVAVAPSFIKELKKEAKCDPDDGDEDYHAAGYGGRGRTNVAKSRPQRSQRTRKRPLRIQEEDSNTDEDEEEEDDDEDDASTSAGSSYHTSTGSGASDRDSPKEPTKTKRGRRSVRGGASASAADSCSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -