Adar001700.1
Basic Information
- Insect
- Anopheles darlingi
- Gene Symbol
- -
- Assembly
- GCA_000211455.3
- Location
- scaffold:55237-60901[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0043 0.25 11.1 3.8 1 23 352 374 352 374 0.95 2 15 5.5 3.2e+02 1.4 0.1 3 8 378 383 377 400 0.87 3 15 6e-05 0.0036 17.0 2.4 1 23 405 427 405 427 0.95 4 15 8.8e-05 0.0052 16.4 1.8 1 23 445 469 445 469 0.92 5 15 0.0034 0.2 11.4 0.5 2 23 475 497 474 497 0.94 6 15 0.0093 0.55 10.1 0.1 1 23 523 546 523 546 0.97 7 15 0.023 1.4 8.8 4.8 1 20 553 572 553 575 0.94 8 15 1.2e-05 0.00073 19.1 4.1 1 23 581 606 581 607 0.97 9 15 0.059 3.5 7.5 0.8 1 23 900 923 900 923 0.95 10 15 0.019 1.1 9.1 0.3 2 23 941 964 940 964 0.90 11 15 0.2 12 5.9 0.1 3 23 971 992 969 992 0.95 12 15 0.00017 0.01 15.5 0.3 1 23 998 1020 998 1020 0.97 13 15 0.077 4.5 7.2 0.2 3 23 1030 1051 1028 1051 0.95 14 15 0.0094 0.56 10.0 3.7 1 20 1057 1076 1057 1079 0.95 15 15 1.8e-05 0.001 18.6 0.1 1 23 1085 1110 1085 1110 0.97
Sequence Information
- Coding Sequence
- ATGGAAGTGAAAATGCAGCACAGATCTCGAGTTCACGTGTTCCAGTTACAGGTCAAAGCGTTGATCAAAGCGCTCAAATGTCTACAGTCGGACGACAAATATCAGGCGCTCCTATTTCTCATCTCAGCCATCAAGCTGTACGTGAAGATACTGTACACCGACTGCCAGGAGCGCATCTATAAACCAGCAATACTCAGAGAGCTGCACAACATCGAGAATGTGATTCTGGTGAACCTGCTCAAGACGCGCGGCAGCGCCGCAGCCTCCGGTTCGTCCTCGGTAGGCACGGGGCACAGTATGCTCTCGCCGTCGTACGGCGGTGCGGAAGGCAAGGTTTCCTGTCTCGACATCAGCAGCACCAGCGTTCGAAGTGCGGATCTATCGATCGGAGCCGATGGACTACTGTTGATGATGCGACAACAGCAGCAGAACGCAAGCAGTGCACCACTGGCACCGTGGGATTTGCGTGGCAAACTGCTGCGGGGCAACCTATTCGATGGATTGCTAGCAGCAACGGCGAGATCGAGTAATTCGACCGTTACAGCGCACCGTCCCCCTCGAAAATGGTTGGGTAATTGGCGAATGAACCGATCGCTGGTGCGGCTGATAGCGAATCACGATTTCAAGCTGCTGTTTAACATGTTCGAGCAGAGCATCTTCCCGACGTGGAAAATCTACAAAAATGAACAGATCTTCGTCCGGAAGCGACCCGCCCTGACGACCGTAACCGTGCGTACCTCGCTACCTGCCCTGTGCTACGGCGAAGGACTTTCGCATTCGCCTCCTGCGACCTACATCAAGAAGGAGGACTACGATTTCGATCCACCGTACTCGCTCACGGACGATCACTGCTTCGAGGACGTTAAGGATGAGGAGGAGGATGATCTGATTCTAAGAATGAAGGATGAAGATTCCATCGATAATTCGAACGAAATCTTCTCCGAAGAAGAATCGTCCACTAATAACACCTCGCTCATGCTGTCCTCTGACACGAACACGCTCGATACGAACGACTCGAGTATGGTTTCACACGAGCGCAACAAGGATCAGGTTTACCAGTGCTTACTGTGTGATAAAAGTTATAGGAAAAGGAAATCTCTCGTCGTCCACTTTAGCCATCATCCTGGATTTTGTCCGGATTGTGGGAAACAGCGTGGTGTTACGTCGGAGGAAATTGTTGAACACAATCGGATATACCACAAAAACCGGCCACACATATGCGAGCACTGCGGCGAAACGTTCACCCGCAACCAGCAGTATCAGATACATGTGCAAGGCCACTTCATCAGCAAGGACCAGGTTGCGGTGCAAAATTGTAAAAAAACCCACAAGTACAGCTGCAAGACATGCAGCATCGTTTTCAACAATCAAAAGTATCTCGAGAAGCACATCCAAAAGACCAACCACCAGGCGGAAGGTTTGGTGTGCGACATTTGTGGTGCAATATTCTGTAACAGTATCAAGCTCAGCCAGCACGTCACCCGAACGCACAACGATGTGTTTACTCAAAAGACGACGCTGGAGCGAAGCTTATTACTTCAGGGCGCGAGCGTAACGGAGAAAAACTATCCCTGCGATCAATGTGGTGCTTCATTTCTATCTCAGCTCTCGTTACGAGAGCATGTCAAAATCTCTCATCCTGTTCCGGAAAACAAGTTTGAATGCAACATCTGCCACAAACTGTTCGCTGCTAAGCGGTCCCTCAAACGCCATAAACTTTGCCATTCGGACGAGCGTGCTTTCCGCTGCACTGTGGAGAACTGCAAGGAATCGTACAAAAACCAATCCCATCTGGCGCGCCACATGAAAACGGCACACCACATTGATCCACCCTCGAAGCGGCTGCAGAAAGCGAAGGCTGCCGCCGCGGCACTTGCATCCTCCTCGTCCTCTTTGACGGGCACGGATCCGACAGCGAGTGGAGAGCTGTTTGCAGGGCACACGGCGGACGCTCAGATGGGAGGCTCGTGTGATTCGCTCAAAGTGACCGGAACACTGAAGAAGTCGCTCGGTAGCAGTGAGAAGTCTCTCGGCGACAGCAGTACCAACTTCAGCGACAATATGTCCGCCTTTAATTACGAGTTTTCCGATACAACCGGAGGTACATCGACACCAGCTATGCCAGTGCACGAGCAAAATCTACTTCCCGCAACCGGTGGTGCATTGATGCCGAACAGCGTTGGTGCTGGTGGTCCGTCGATCATCGGTAACAGGACAGCTGCTCTCACGTGTGCGGTGGGCCCGGGACAAGGTCCGACAGGTGCTTTCAATGATCCGACGATAGGCTTCGGGAACAATAACGGTGCCAGCAAGCAGCAACATCTAGCACATCAGCAATCGCTACCACAACACCAGCAGCAACCGGTGCAGCAACACATGGGATGGCAGAATCTCGAGTTCGGTTCGGGTGCACATCGAACATCGATGATACCGGATGGTGGCGGCAGTGGCAGTAATATTCCGCTACAAGATCCACTAGCCACTACCCCTACCAGCTTTATGGATGGCGCacagcagcaacagcagcatcagcaATCGCCACACCATCACCCCACTCATCCACAGCATCACCATCTACATCACCAACAGCAACAGCTTCATCATATGGGTAACGCGCTGGCCAGTGGTGGATCAGGTGGTAGTAGCGGGTTTATGGGGTCAAGCGGTGCTAGGCGATTCAATCTCCCGGAAAACAGCTTTATCTGCGAGCATTGCGATGAAACCAACTTCATCAACGCGCAACAGTTTCAGCTACACATTCAGGATCACTTTGCGGGCAAGGAGGGCAAGGAGCATCCCAGCAAAAAACTACAACGATTGAATTGTAAAACGTGCAGCCTGGTGTTTGCCACTGGAGCCCAGCTCGATCGGCACATCCAGAAGACGAACCATCACACCGAATGCATAGCGTGTGAAATTTGTAGTGCAATATTCAACTCTAATTTAAAGGTTTACCAGCACATGCTGAAAGCACATAAGAATGATATGTGGTACGCCTGCGAACAGTGCTCAAAAGTGTTCACCGTGAAAGAGGAGTACGACAAACATCAGCTAGTGCACCAAACAGTCACGGACCGGTCCATCATTTGTGAGCACTGTGCATCGTCCTTCCTCACGCAAGAAGCCCTGAAGGAACATATCAAAATAGCACACTCGATGGATAAAAAATACAAGTGCACCATCTGCAACAAGCTGTTCGCTGCACGGCGCTCACTGAAGCGCCACAAGCTTTGCCACGAAGAAGAAGCCGCCTTCCGCTGTCCGATCGATGGTTGCAACGAAGCGTTCCGTACGGCGGGCAATCTGGCGAAGCACAAAAAGATGGCCCACCCAGCTGGAGCACCGTCTTCGGTGGTGGCCAACGCAGCTACTATTGCCAATGCCGCTGTTGATCCGCTGAACGAAAAAATGACTGCCAGCGGGACAGGTCTGGTGGGCCAGGGAAGTAAACACCCGAACGCGCTGGCTGCATCGAATGCTACCGGCGCCTTAGCGGTGGGCACGATGAAGATACCGGACAAGTCACATTCACAAGACATGATGGGCAGGGGTCTAGGCAGTCAGGGATCCGGGCTAATGTCACCGGCTGGTCCGGCAGGAAGTGTTGGCATGATGAACCTGGCATCCGGTGGTATGATGAGTGGTGGTGGTGTTGGTGGTCCAGCACACAGTAAGAGTGAGCGATCAGCCGCTGGCGGACTGATGGTACCACCTTCGAGAACGCCCAGTGCCGGGAGCAGTGTCGGAGGCAACCAAGCCATGCCTTACAGCCCATATGATGGGACCAATGCCGCCATGCATTacaacagcaatatgctcggtccacccggtccacaacatccacatcatcctcatcagcagcatcaccaacagcagcagcagcagcagcagcagcaaccacagcctcatttagggcatcagcagcaacagcagcatcatcctcaagcaccacaacactctctgcatcatccgCAATCTCAGTACGTTGGTATGACAGGAGGCCAGGGTTCTGGTGGTAGTGGGCCTGCCGGCATGCACTACGTTTCGCCTGGTCACGGGTTACGAACGACAGTTCCTGGCGGCACCGGTGCAAGCAACCCAGTTGAACAGCAGCCATCAGTGTCTGGTTATCGAATGGCGGATGGAGCGTCTGGTGCAGCTGCTTCTAGCAGTGGGAATGTACCGAATGCTTCTAATCTTCCATACGCTTACGGGCAGCAGACACAGAATCAGTTCGATTGGCAAACTATGGAACAACTCGGTGGCCAGATCGGTAATGCTGAATCGGGTGTAATAGGAGCAGGGCCGATAGGTAGTGGAGCAGGTGGTGTTCCAGGTGGAGCAATGAAAAGCAGTAAATACTATAACCCAATGCACGACGGTAATGGTTCAGCGGCAGCTGCTGGGGGGTTCCTGTCGCCTcagcaacaacaacaacagcaccagcaagtgcaacaacaactaccacatcaatcctcacatcaccacacccagcatattcagcatcagcaacatgctcagcttcagcagcagcagcacagcaacagcaacaacaacagcagcagcagcagcatctacCGCATGGCCATTCACATTCGTCACCACAAGCGAGTGGAATGCAGCAGAGCAAACCCCCAGCACAAGGTCATTCCCAGCAGCAGCATATGA
- Protein Sequence
- MEVKMQHRSRVHVFQLQVKALIKALKCLQSDDKYQALLFLISAIKLYVKILYTDCQERIYKPAILRELHNIENVILVNLLKTRGSAAASGSSSVGTGHSMLSPSYGGAEGKVSCLDISSTSVRSADLSIGADGLLLMMRQQQQNASSAPLAPWDLRGKLLRGNLFDGLLAATARSSNSTVTAHRPPRKWLGNWRMNRSLVRLIANHDFKLLFNMFEQSIFPTWKIYKNEQIFVRKRPALTTVTVRTSLPALCYGEGLSHSPPATYIKKEDYDFDPPYSLTDDHCFEDVKDEEEDDLILRMKDEDSIDNSNEIFSEEESSTNNTSLMLSSDTNTLDTNDSSMVSHERNKDQVYQCLLCDKSYRKRKSLVVHFSHHPGFCPDCGKQRGVTSEEIVEHNRIYHKNRPHICEHCGETFTRNQQYQIHVQGHFISKDQVAVQNCKKTHKYSCKTCSIVFNNQKYLEKHIQKTNHQAEGLVCDICGAIFCNSIKLSQHVTRTHNDVFTQKTTLERSLLLQGASVTEKNYPCDQCGASFLSQLSLREHVKISHPVPENKFECNICHKLFAAKRSLKRHKLCHSDERAFRCTVENCKESYKNQSHLARHMKTAHHIDPPSKRLQKAKAAAAALASSSSSLTGTDPTASGELFAGHTADAQMGGSCDSLKVTGTLKKSLGSSEKSLGDSSTNFSDNMSAFNYEFSDTTGGTSTPAMPVHEQNLLPATGGALMPNSVGAGGPSIIGNRTAALTCAVGPGQGPTGAFNDPTIGFGNNNGASKQQHLAHQQSLPQHQQQPVQQHMGWQNLEFGSGAHRTSMIPDGGGSGSNIPLQDPLATTPTSFMDGAQQQQQHQQSPHHHPTHPQHHHLHHQQQQLHHMGNALASGGSGGSSGFMGSSGARRFNLPENSFICEHCDETNFINAQQFQLHIQDHFAGKEGKEHPSKKLQRLNCKTCSLVFATGAQLDRHIQKTNHHTECIACEICSAIFNSNLKVYQHMLKAHKNDMWYACEQCSKVFTVKEEYDKHQLVHQTVTDRSIICEHCASSFLTQEALKEHIKIAHSMDKKYKCTICNKLFAARRSLKRHKLCHEEEAAFRCPIDGCNEAFRTAGNLAKHKKMAHPAGAPSSVVANAATIANAAVDPLNEKMTASGTGLVGQGSKHPNALAASNATGALAVGTMKIPDKSHSQDMMGRGLGSQGSGLMSPAGPAGSVGMMNLASGGMMSGGGVGGPAHSKSERSAAGGLMVPPSRTPSAGSSVGGNQAMPYSPYDGTNAAMHYNSNMLGPPGPQHPHHPHQQHHQQQQQQQQQQPQPHLGHQQQQQHHPQAPQHSLHHPQSQYVGMTGGQGSGGSGPAGMHYVSPGHGLRTTVPGGTGASNPVEQQPSVSGYRMADGASGAAASSSGNVPNASNLPYAYGQQTQNQFDWQTMEQLGGQIGNAESGVIGAGPIGSGAGGVPGGAMKSSKYYNPMHDGNGSAAAAGGFLSPQQQQQQHQQVQQQLPHQSSHHHTQHIQHQQHAQLQQQQHSNSNNNSSSSSIYRMAIHIRHHKRVECSRANPQHKVIPSSSI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092335;
- 90% Identity
- iTF_00092335;
- 80% Identity
- -