Adar009446.1
Basic Information
- Insect
- Anopheles darlingi
- Gene Symbol
- -
- Assembly
- GCA_000211455.3
- Location
- scaffold:30483-38159[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.066 3.9 7.4 1.5 1 22 185 208 185 210 0.86 2 11 5.7e-06 0.00034 20.2 1.1 1 22 226 247 226 247 0.96 3 11 0.0013 0.079 12.7 0.2 1 23 252 275 252 275 0.98 4 11 3.3 2e+02 2.0 0.1 3 20 297 314 296 318 0.86 5 11 0.0015 0.087 12.6 0.9 2 20 333 351 332 353 0.94 6 11 0.082 4.9 7.1 0.8 3 23 362 382 360 382 0.92 7 11 4.4e-07 2.6e-05 23.7 0.0 1 23 388 410 388 410 0.97 8 11 0.011 0.67 9.8 4.5 2 23 416 437 415 437 0.97 9 11 4e-07 2.4e-05 23.8 0.2 3 23 445 465 443 465 0.96 10 11 0.0026 0.15 11.8 1.1 1 23 471 493 471 493 0.97 11 11 3e-06 0.00018 21.1 0.1 1 19 499 517 499 520 0.94
Sequence Information
- Coding Sequence
- ATGATCCGAGAATGTTGTGCGTGCAGGATAAAAACGAAAGACTCGGTCTCGATCAACGCCAAACGGCAATCTTGCACACTGGCGGATATGCTGAAAAAGCTGGCACCGATACAGTTTTCAGCGATCGATGCCGACGGAGCGGAGGTTATCTGTGCGGATTGCGTGGAACACACGGTTGATGCATACCGATTTTTAGAACTGGTGGCTAGGGCCAACGAAGAGAGAGATCTTGAGGACGATGGCGAGATCTTCTCATTGCCCGTTGACATACCGTTTCCGTCCGGAACTGTTGAGTTGACCATTGAACATCCGGAAAGCCTGGGTGATTTGCAGTATTTCATTCAACAGGAAATCGAGGAGCTGATAGAAGGGGACAGTTATATCGAATCTCCAATGAGTGATTCTTCAACGCCAACtgatgatgatgatgataatgatgaCGAATCGCAAGATGAATCAGAACCTGTTGACCCAAACGACGACGGTGACGTTGTTGAAGGTGGTCTCAAGCATGTCAATTACTACCCAATATTAGCTAATGGAATTGCCTATTATCGCTGCTGTGGCCGTAGATGCTGGCAAACGTTTAATTCTCGAGAAGAGTTGGAATACCATGGAGCACAGAATCACGCAGCCAGCAATAGTAACAGGGCACACTATGACGATTCTTATGGTTATGAATGCTCCATTTGCTATCGTCGATTCCAGCGGCGATCAAATCTAATCAACCATCTGCGACGTGTGATTCGGGATTACGAGTGTGCGCTATGTAAAGTTATCTTCGACCGACCGAAAGACAGGGAACAACACATGATCACACAGCATCAGAGCTATCTGCATGCAAAACGACGAAAACGTTACGAATTGGATCAACAACCTCACAAAATATGCTGCGGCTGTGGTGATCGCTTCGACACCGTACCAGAGCTACTGGAACACGGCACTGCAGCCCATGCTATGCACCCGCATCGCCAGGATAGCGATGGCTACGATCTGCAATGTGAGGTTTGCTACCGGTATTTTAAACATCGCACCGGTCTTCGTAACCATCAGACGGCCGTGTATAGAGAGAAAAAACTGTCTTGCATTCAGTGTGGGGCTGCTTTTAGTTGTCAGTCGAAATTGGAATCCCACGAGCAGACACATGCGGTTGATAGGAGCTACGTATGCGAGCAATGTGGCAAAGCTTTTAAAACACCTGCGGCACTACGAGCCCATGGACAGGTTCACCAGGAACGTACACTTCAGTGTGACATTTGTAGCCATCGGGTACACAAGAAATCACAGCTGGTGCAGCATCTTAAACGGCACGAACCAGTACTGCCCATCGCGTGCGCCCTCTGTCCGAAACGATTTCGGTATCAGTCTAATCTCGTCAGCcatatgagggtacacacgggtgagaagtcatacgcttgtcggtattgtgatcggcggtttggctatgtcagcgatcgacttaagcacgaacgatcacacaccggagattatccgtacagctgtgaggtctgtggcaagaaattcgttcgaccaTCGTCCCTTCAATTGCACGAGGCAAGCTGTCGTGTCTAG
- Protein Sequence
- MIRECCACRIKTKDSVSINAKRQSCTLADMLKKLAPIQFSAIDADGAEVICADCVEHTVDAYRFLELVARANEERDLEDDGEIFSLPVDIPFPSGTVELTIEHPESLGDLQYFIQQEIEELIEGDSYIESPMSDSSTPTDDDDDNDDESQDESEPVDPNDDGDVVEGGLKHVNYYPILANGIAYYRCCGRRCWQTFNSREELEYHGAQNHAASNSNRAHYDDSYGYECSICYRRFQRRSNLINHLRRVIRDYECALCKVIFDRPKDREQHMITQHQSYLHAKRRKRYELDQQPHKICCGCGDRFDTVPELLEHGTAAHAMHPHRQDSDGYDLQCEVCYRYFKHRTGLRNHQTAVYREKKLSCIQCGAAFSCQSKLESHEQTHAVDRSYVCEQCGKAFKTPAALRAHGQVHQERTLQCDICSHRVHKKSQLVQHLKRHEPVLPIACALCPKRFRYQSNLVSHMRVHTGEKSYACRYCDRRFGYVSDRLKHERSHTGDYPYSCEVCGKKFVRPSSLQLHEASCRV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092314;
- 90% Identity
- -
- 80% Identity
- -