Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:11583-17183[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.057 3.4 7.6 3.5 1 20 213 232 213 235 0.94

2 14 0.0011 0.063 13.0 4.7 1 23 241 263 241 263 0.97

3 14 0.0017 0.1 12.4 0.1 1 23 411 433 411 433 0.98

4 14 0.0014 0.083 12.7 0.1 2 23 440 462 439 462 0.95

5 14 3.5e-05 0.0021 17.7 0.7 1 23 517 540 517 540 0.94

6 14 0.0058 0.35 10.7 1.0 2 23 635 657 634 657 0.94

7 14 0.0072 0.42 10.4 1.5 2 19 665 682 664 683 0.95

8 14 0.0016 0.097 12.4 10.0 1 23 692 714 692 714 0.96

9 14 0.00099 0.059 13.1 1.1 2 23 720 741 719 741 0.97

10 14 7.5e-06 0.00045 19.8 0.3 1 23 747 769 747 769 0.98

11 14 0.00073 0.043 13.5 0.2 1 23 775 797 775 797 0.97

12 14 0.00069 0.041 13.6 0.6 3 23 805 825 803 826 0.95

13 14 0.06 3.5 7.5 0.0 1 23 840 862 840 862 0.96

14 14 0.00027 0.016 14.9 1.6 1 23 1536 1558 1536 1558 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.057	3.4	7.6	3.5	1	20	213	232	213	235	0.94
2	14	0.0011	0.063	13.0	4.7	1	23	241	263	241	263	0.97
3	14	0.0017	0.1	12.4	0.1	1	23	411	433	411	433	0.98
4	14	0.0014	0.083	12.7	0.1	2	23	440	462	439	462	0.95
5	14	3.5e-05	0.0021	17.7	0.7	1	23	517	540	517	540	0.94
6	14	0.0058	0.35	10.7	1.0	2	23	635	657	634	657	0.94
7	14	0.0072	0.42	10.4	1.5	2	19	665	682	664	683	0.95
8	14	0.0016	0.097	12.4	10.0	1	23	692	714	692	714	0.96
9	14	0.00099	0.059	13.1	1.1	2	23	720	741	719	741	0.97
10	14	7.5e-06	0.00045	19.8	0.3	1	23	747	769	747	769	0.98
11	14	0.00073	0.043	13.5	0.2	1	23	775	797	775	797	0.97
12	14	0.00069	0.041	13.6	0.6	3	23	805	825	803	826	0.95
13	14	0.06	3.5	7.5	0.0	1	23	840	862	840	862	0.96
14	14	0.00027	0.016	14.9	1.6	1	23	1536	1558	1536	1558	0.97

Sequence Information

Coding Sequence: ATGGATTCTCGGTTCTCCTCGCTAGCATCGGCTGGCGGAAGTTTGAAAATCATCAACATCGGAGCCAGCCAAACCAGCAGCAGCAGCAGTACTGGCGGTGTTGGTGGGGGTCGCGTGGTGCACAGCACCGCGACGATCGCCAGAGATCCGTTCCCGCATCAATCTGGCGGGCAAACATTTACGATTGCAAACGAACCGATCCTGTTGCAATTACACGACGGTAAACAATACCTCGTTGATGAGAGTTCGATCAGCAACATCGATCAGATGCCACCAGAGAATCTAATCTACATGAACCCGACGTCTGCCGTCATTGACGATGGGTCGTTCGAAACGACAGAAGAACTGGTCCAACTGGTAACTTCCGAAGAAATGGCGGAAACCAGTGGGCCGCTGCAGTCGAATGATCCTAGTAATGAACAACATGAGCAGCAGCAGCAGCAACAACAACAGTATAAGGAGTGTGAGGAGCTGGTGATGGAAGAAGTGATCACCGATGATTGGGTGCAATCGCAGGACGATGAGTGCGTGACGGTATCTATAGATCAACTTGGTGGTAGTACCGTTGGCGGAACTACCCTAGAGGACGATATTTCAGTTCCGCTCGATCAGGACAAGTACACACTGTCGCGACCCTTCCCCTGTGATTTCTGCAGCCGTCGGTTCCGGAAAATGACCAGTCTGGAACAACATCTGCTATGCCATTCGAACGTGCGGCTGCACACTTGCAATCTATGCAACACGCACTTCGAGAAGCGCAGTGATCTGACGGTCCATTTGCAGCAGCATGCATTTCTGTCCAACGAAAACGACGAAACGTTTGCCAGCGACCACGGAGGAGACTATGATACGACAATCTCCCGCCCTAATCAGCAATACCGAGCGCATCATTCGAGTGATGATGACGAGACTGCAATTTACATTGAGAATGCCGGTATGGGCTACAACGCTCAGCCACCAATGCAGCTCATATCGACTTCACCATCCTACGGTAGCGCGCATGCTAGCCCTAACCGATCGCTTATGGATGGTGTAGGACCTTCGACGATGTCCGGTAGCAATGCCTTCACCGACCAGCAATCGCATCGCACCAAACAGGCCAGATCGCCGCGTTCAGGACGTTCAACTCGTCCTTATATTAAACAGGAACCAGGCACTAGCTCTTCCTACCCGAATGAAAACGAAGTATCGCCGAGTGTTCCCTTCCCGGTGAAGGATCCACGCAAACCGTTCGTTTGTCAGCAGTGCGGTGTGGGGTTTGCACGTGAAAAAGCACTCGATTCGCACTCACGCATCCACGGGGGTGATTCGAAGATTGAGTGTAGTGTATGTGGGGAAATGTTTTGGAATCCGACGCAGTTGCAGTCACACGTACGCCAGCGACATCCGGAGGGAGAACAGAAGGGTGCCAGGAAACGCAAAGCCAGCGCTGTAACAACAACACACACCACAAAAACATCTTCCTCCTCCTCCTCAGCGTCACGAGGACATGCGTTTGAGGTCGAAACGCAAAATGATGATGATTTCGATCTGCTGCTGGATCCTCCACATGACTGTGATAACTGCGGTGCGTCATTTTCCCAGCCAGAGCGCCTGAAACGGCACATCCAGCAGATGCACGGATTGCTGCCATCCATCATCATAAAGCAATCGTACGATCCGTCAATCGTAAAGCAAGAAGTAAATATCGATATATCGACCGGATACGAGTACCAACAGAACCAGGTGCAGCAACGGCATCAGCAGCAGGAGCTTGATGATCATGATCCAGAGGAGGATGACGAGGAGGAAGTGGACTCGGGTGATGATTACAGTGACGATAGAACAGTGGTAACGCTGGACAAGTCTTCCGTATACGAAGGTCATCTATCGCCGCTTGAGACAGAGCTAGCGGTACCGATCAAATGTCAATTGTGTGGGGAAACGTTTCAAAGCGAACATGAAATCAAACAGCATCTGCAGGAGCAGCATATGGAGCAGATGACACCGACATCGTGCGTGATATGCGGCAAACGTTGCACAAATCATGCTTCTCTCATAAAACACTCGTGGGACCATTCGCGCGTCCGTCGGCACTGTTGCCCGCAGTGTGACAAAACGTTCCACCACAAGGCCCGCCTGAAGCGCCACATGGAATCGCATCGCAACAAGTCAGTCAAGTGTCAGCAGTGTGGCGAAAGCTTCCCCGACGGTCGCAGTTTGATGAACCATCGACATTCGCACACCAAATCCAGTAAGTTTCcgtgtactgtgtgtggcaaaacgtttggttcgcgatcatctcagcagatacatcttcgtattcatacgggcgagcggccttacgcatgtcggttctgctggaaagcgttcgccgATGGTGGCACGCTGAGAAAACATGAACGGATCCATACGGGCGAAAAGCCGTACGGGTGTTCAGTCTGTACCAAGGCGTTCAATCAGCGTGTAGTGCTTCGCGAGCATATTCGGGCCCATCATTCGCAAATCGATAGCAAACGAGGTACGCCCGAACAGCCCTACTACTGTGACGCCTGTGGTGCGCTCTTTGCTTCGTCGATCGAGCTTGTGCAGCATCTGATTGAGCACAGCGATAAGACAACCGCGGACAAGCGTAAGCCACAGATCTTCCCGCGTAAATACAAACGTCGTCGGAAACTGAAACCGCAAGAGCTGGAACGGTTACAGAACGGCCGCCGCAAGAAGAAACCCTCAACAGCCGCCATCACCAGGAGCACTAGCCAGGAGGACTTTGATGAGGATGATGTGCAAGAGGCAACTAGTACGAAACAATCACAAGCACAAGATGACAGCAACGAACAGGGCGATGATCATGAAGAGGACACTGACTCAAGCATCGACCAACCGTCGGACACAACAAGCGCTAATAACTCCCTGGACAACGGCGATGCATCATTGAAAATATCTAGCGAACTGTTTCTAGATTACGGCGGTGGTTCCGTTCAGAAGGTTATCGCTTCTCCGAAATTCATCTCGCCTTACGAGTTGCTCGACGATGCCCAAAAGGAGGCAGATGAGTTGACAACTAAACCTTCATCACACAAACTAATACCGCTGCCGAACGCTGGCGTAGATGGAGAGATCATCATCATGGACGATCACGGCATTAATCTGCTGAGCGAAGTGGTGCTCGTCCATGGAGTGAACAACAATCATGATAAATCGAAAAAAGCCACGGCAGAGACGAAGCAACCGAAAGTCGCCGGTTCTGTGCCACGCACAATAAGCAGCCCCGTGAAAGCAAAACATAcctcatcatcctcatcatccCCGTCGACGAAAGACAGCCGGAATAAGAAACAGGTACACGCATCTGCCGGCACTCTAACCAAATCTGGTGTCTCTTCCGCTTACAATGCTGTGACAGGGGGCGCAAATAATGCTACTCCAACCGTGACGACATCCGCGAACAGCATGGCGACATTTTCCGCCTTGGCGAGCAGCCGATCGCATGGCTCTCGTGCCCTGCCTTCGTATGTTCGGGAAATATCGTCCTCTAGAATCTCTTCCGGAAGTTTCCCTCTGCTAGACGACGGCAAAAGCGCGCACGATACTCTGGAAGATGAGGAGGCGATGATTGGCGAGCAAAGCATCGATCATGCGACAACGGACGGACGTGGTAGTACTGTTGGTAGTGAAGAGCGTCGAAGGCGGCGGCGACATTTCTCGTCGACAAGCAGTTGCTATGACCACGGCACAGCAAACGATGAGGACGAGCTTAATGAACTGAATCAAAGACTGCTGACCGAGATTTCGAATAGAGATCGCTACACTGATCGCTACAATAGCGACATCGTGAACGATCTGGCGGAAATACTGCGTTCACCTATCAAAACTGTGCCAATAAACGGGCCACCACGTGACATACTGGCGACACCGTCTGCCCAGCGTGCCCTACAATTCTTCGAAACACCCACTACCACCGGTCTGTCCAGCGTGGATGCACTACTACCCCTTGATGGGGTAAAGCTAGAGATTGTAGATGAAGACGCACCACCGTCTGAAGTCGAAAAAAGGGAAGCAGCTAGTCGTCGGCGTAACAACAATAAGGATTCCCAATCATCAAAGCAACATACGAAAAGAGTTTCATCCGGCAGTATGCGCACCGGATCGTCTCCGCTACGTATTCCGCGGTTAACAAGGCGCCAGTTAGAAAAGGAGATAAACTTTTTAAAGGAAGCTTTTGGAGGAGGAGACGATACCTCTACCGGCGTCCCGGATGCATTGCCAGTCGAGGCCTTTGGAAGACAGAGTGGAGATAGTTTTTCTATCGATGAAGACAAATCTACGGTAAAGATTGGACATAGCGCCAAAATCAATGCCTCCGAGGAGTTGGCTACAATGCTGCTCAACGATCAGATTCCCACCACTAGCGGGCGGCAACGTGAGAGGCAGGAAAAGGAGGACATCGAAGCGACCATGGAAGGCAATGCGGTTACTATCGTCAAACAGGAGGCGGTTGACTATAGCGAAGATATTGATAACGACGACGATATGTTCGGTGGTTTTGGGTCCGATGTGGGACAGGAAGCGAGCGATGGAGAATCGACGGACCTTCAATCGGCTACTGACTCGTCGTTTGCCGGCTTTCGATGCTCGATATGTGACGAGTGTTTCGAGGAGCGGAAACAACTAATGCTACACGTTCAGTTGCACATCTAA
Protein Sequence: MDSRFSSLASAGGSLKIINIGASQTSSSSSTGGVGGGRVVHSTATIARDPFPHQSGGQTFTIANEPILLQLHDGKQYLVDESSISNIDQMPPENLIYMNPTSAVIDDGSFETTEELVQLVTSEEMAETSGPLQSNDPSNEQHEQQQQQQQQYKECEELVMEEVITDDWVQSQDDECVTVSIDQLGGSTVGGTTLEDDISVPLDQDKYTLSRPFPCDFCSRRFRKMTSLEQHLLCHSNVRLHTCNLCNTHFEKRSDLTVHLQQHAFLSNENDETFASDHGGDYDTTISRPNQQYRAHHSSDDDETAIYIENAGMGYNAQPPMQLISTSPSYGSAHASPNRSLMDGVGPSTMSGSNAFTDQQSHRTKQARSPRSGRSTRPYIKQEPGTSSSYPNENEVSPSVPFPVKDPRKPFVCQQCGVGFAREKALDSHSRIHGGDSKIECSVCGEMFWNPTQLQSHVRQRHPEGEQKGARKRKASAVTTTHTTKTSSSSSSASRGHAFEVETQNDDDFDLLLDPPHDCDNCGASFSQPERLKRHIQQMHGLLPSIIIKQSYDPSIVKQEVNIDISTGYEYQQNQVQQRHQQQELDDHDPEEDDEEEVDSGDDYSDDRTVVTLDKSSVYEGHLSPLETELAVPIKCQLCGETFQSEHEIKQHLQEQHMEQMTPTSCVICGKRCTNHASLIKHSWDHSRVRRHCCPQCDKTFHHKARLKRHMESHRNKSVKCQQCGESFPDGRSLMNHRHSHTKSSKFPCTVCGKTFGSRSSQQIHLRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYGCSVCTKAFNQRVVLREHIRAHHSQIDSKRGTPEQPYYCDACGALFASSIELVQHLIEHSDKTTADKRKPQIFPRKYKRRRKLKPQELERLQNGRRKKKPSTAAITRSTSQEDFDEDDVQEATSTKQSQAQDDSNEQGDDHEEDTDSSIDQPSDTTSANNSLDNGDASLKISSELFLDYGGGSVQKVIASPKFISPYELLDDAQKEADELTTKPSSHKLIPLPNAGVDGEIIIMDDHGINLLSEVVLVHGVNNNHDKSKKATAETKQPKVAGSVPRTISSPVKAKHTSSSSSSPSTKDSRNKKQVHASAGTLTKSGVSSAYNAVTGGANNATPTVTTSANSMATFSALASSRSHGSRALPSYVREISSSRISSGSFPLLDDGKSAHDTLEDEEAMIGEQSIDHATTDGRGSTVGSEERRRRRRHFSSTSSCYDHGTANDEDELNELNQRLLTEISNRDRYTDRYNSDIVNDLAEILRSPIKTVPINGPPRDILATPSAQRALQFFETPTTTGLSSVDALLPLDGVKLEIVDEDAPPSEVEKREAASRRRNNNKDSQSSKQHTKRVSSGSMRTGSSPLRIPRLTRRQLEKEINFLKEAFGGGDDTSTGVPDALPVEAFGRQSGDSFSIDEDKSTVKIGHSAKINASEELATMLLNDQIPTTSGRQRERQEKEDIEATMEGNAVTIVKQEAVDYSEDIDNDDDMFGGFGSDVGQEASDGESTDLQSATDSSFAGFRCSICDECFEERKQLMLHVQLHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092309;
90% Identity: -
80% Identity: -