Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:201867-203995[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00054 0.032 13.9 0.1 2 23 102 124 101 124 0.96

2 15 0.083 4.9 7.1 0.1 1 23 130 153 130 153 0.90

3 15 4.9e-07 2.9e-05 23.5 3.2 1 23 160 182 160 182 0.98

4 15 2.1 1.3e+02 2.6 0.4 1 22 185 206 185 208 0.78

5 15 0.047 2.8 7.8 2.9 1 23 213 236 213 237 0.96

6 15 0.11 6.4 6.7 0.1 1 23 243 269 243 269 0.90

7 15 0.0018 0.11 12.3 0.9 1 23 392 416 392 416 0.93

8 15 5e-05 0.0029 17.2 0.3 2 23 422 443 421 443 0.96

9 15 0.00097 0.058 13.1 3.7 1 20 483 502 483 504 0.95

10 15 0.41 24 4.9 1.8 2 23 520 541 519 541 0.96

11 15 2.4e-05 0.0014 18.2 1.6 2 23 550 571 549 571 0.97

12 15 1.8e-07 1.1e-05 24.9 0.4 1 23 577 600 577 600 0.97

13 15 9.6e-07 5.7e-05 22.6 1.4 3 23 608 629 606 629 0.97

14 15 2.5e-05 0.0015 18.1 1.9 1 23 635 658 635 658 0.91

15 15 0.00022 0.013 15.2 0.8 1 23 663 686 663 686 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00054	0.032	13.9	0.1	2	23	102	124	101	124	0.96
2	15	0.083	4.9	7.1	0.1	1	23	130	153	130	153	0.90
3	15	4.9e-07	2.9e-05	23.5	3.2	1	23	160	182	160	182	0.98
4	15	2.1	1.3e+02	2.6	0.4	1	22	185	206	185	208	0.78
5	15	0.047	2.8	7.8	2.9	1	23	213	236	213	237	0.96
6	15	0.11	6.4	6.7	0.1	1	23	243	269	243	269	0.90
7	15	0.0018	0.11	12.3	0.9	1	23	392	416	392	416	0.93
8	15	5e-05	0.0029	17.2	0.3	2	23	422	443	421	443	0.96
9	15	0.00097	0.058	13.1	3.7	1	20	483	502	483	504	0.95
10	15	0.41	24	4.9	1.8	2	23	520	541	519	541	0.96
11	15	2.4e-05	0.0014	18.2	1.6	2	23	550	571	549	571	0.97
12	15	1.8e-07	1.1e-05	24.9	0.4	1	23	577	600	577	600	0.97
13	15	9.6e-07	5.7e-05	22.6	1.4	3	23	608	629	606	629	0.97
14	15	2.5e-05	0.0015	18.1	1.9	1	23	635	658	635	658	0.91
15	15	0.00022	0.013	15.2	0.8	1	23	663	686	663	686	0.96

Sequence Information

Coding Sequence: ATGCAGTCGACTCTAGATGCAGTTCTGTGCAAATGCTGCGGTGATACAGCAGGACATCGGTTTCAAGGATTACACCAGAACGTGTCGGTGAATGGAAAGGAGCTGATGGTGCGCAAAATGTTTGATATATTCCACATTCCTCAGGAAATTTGCTTAGTGGAAGAGGATGTTGTGTGTGAACACTGCTTGGAACAGCTGAAGTTCTGCTACCAATTTTACGATAAATTCCTCGACGTAATAGCATCTGCCACTAGAGTACCTCCACGCAGTCTTCAGATTCTCGAGCAGGACGAAGTATCGCTTACTTGCAGCTTGTGTGAAGCCTCTTTCGTCAATAATTTAGATTTGGAAAAGCATACCAAAATCATCCACTCACCCGGGAAGTACTACTACTGTGCGGCGTGTGAAAAGTATTTCATTACCAAGCGAGGCATGATACAGCATACGGCAGCGATTCACCATGATGCAAGCGAAACGTTCTCGTGTGACATTTGCCAAAGATCTTTTACTACGAGAAACAACTACCAGAATCACATGCGATATCACAAGGATTATGTGTGCCATTTCTGTAACACCGGTTGGTTAACTGAGTCCAACTTACTGCAGCATGTCAGTGCGAATCACGCCGATCGCCTGTTTGTGTGCCCGTTCTGCGATCGCAAAGATCGATTGCGGAAAACTCTCAACCGGCACGTGCGATCCAGTCATCATCCACAAAGCTGTGTTTTCTTCTGTGGCTACTGTGGTATCGGTAGTACGGGCTACGATAATTTAGAATCACTAAACGACCATCTGAGGCAGTTGCATGAAGAAGAGAGCGCACCAGCGAACGCATACGATCACCTGTTGAACGACAGTCTGTTCGTGAAGGAGCTACCAGCGCTGGAACTAGCACCGCCTGAATCCATCGACAAAGAGCAGGAAGAATTTCTACAAAATGTAAATCTAACCCGCACCAACCAAAGCAACGAAAGCAGCAAAGTAAAACCGGATGGCGGCGGGTTAGCCGAAGCGAGGTTTGATCAAAAGACTGTGCTGGAAGACTTTCTGGATGAGGCGTTCGAGAACAACGAAATATGGGAAAAGTACATCGAGAACGGTGAAGAGTATCTGATCGATGATTACGACTTCTACCTGAAAAGGATAGAGGAACCGCAGCAGGAATCGGGCAAATATCCTTGCCCGCACTGTAGTGATCGTAGTTTTTCGAAGCAGTTCCAATTGATGGTTCATTTGGCGGAACAGCACGATATCGCCAGCCTGGTGTGCAACGATTGTGGTGCGAGTTTTGCAAGCCTGCAGAGCTACCGCACACACCGTCGGGAGCACATGAAGGAGAACGTTCGCTTTCGGGAGAGCAACATCCCGGAAGTGGAGGAGGCGCTGTCGCTGGTTCATAGTACCGCATTGGACTATACGGTTCGCGAGGAAGAGAGCTGTTACCGATTCACATGTAGCCTGTGTGATCGGTCATTTTTGCGAAAGCACAATTTAGAGAAACACACGTGTGCCTTCTACAAGCGCCATCAACAGGAAACGGGCGAACGGCCGACAATTAGGTGTCAGTACTGTGATTTTCAATCCCACGTCGCGAAGGAGGTATTCATTCATCAGCGCAAGCATCAAGAGGAAGGCCAGGAAAGTATCTACTGCACGCTGTGCGATCGTCGATTTAGCTCTACCTCTGGGCTAAAGTATCACCTAAAGCGCCACACGGGCATCAAGGCATTTACATGTTTGTACTGTGGGAAGAACTTTACGGCCAACTCGAACCTTAACGCTCACATAAGGAATGTACACAGTGACCACAAGTCATTCGGCTGTCCGGAGTGTGAGGAAACGTTTGCCTCGAAAGACCACCTGAACAAGCACCAACGATCACGCCATCGCCAGGAACGCTCATTTGTGTGCAGTGACTGTGGAAAGGCCTACTTCCAGCGTTCACATCTTAATGAACATGTGGCTGCCTGCCATCGAGAATATCGGTATCGGTGTAACATTTGCAACAATTCATACGCCGCGCGTGGTTCTCTGAAAAGACATCAGCTGCAGAAGCATCTTTTGGACTAA
Protein Sequence: MQSTLDAVLCKCCGDTAGHRFQGLHQNVSVNGKELMVRKMFDIFHIPQEICLVEEDVVCEHCLEQLKFCYQFYDKFLDVIASATRVPPRSLQILEQDEVSLTCSLCEASFVNNLDLEKHTKIIHSPGKYYYCAACEKYFITKRGMIQHTAAIHHDASETFSCDICQRSFTTRNNYQNHMRYHKDYVCHFCNTGWLTESNLLQHVSANHADRLFVCPFCDRKDRLRKTLNRHVRSSHHPQSCVFFCGYCGIGSTGYDNLESLNDHLRQLHEEESAPANAYDHLLNDSLFVKELPALELAPPESIDKEQEEFLQNVNLTRTNQSNESSKVKPDGGGLAEARFDQKTVLEDFLDEAFENNEIWEKYIENGEEYLIDDYDFYLKRIEEPQQESGKYPCPHCSDRSFSKQFQLMVHLAEQHDIASLVCNDCGASFASLQSYRTHRREHMKENVRFRESNIPEVEEALSLVHSTALDYTVREEESCYRFTCSLCDRSFLRKHNLEKHTCAFYKRHQQETGERPTIRCQYCDFQSHVAKEVFIHQRKHQEEGQESIYCTLCDRRFSSTSGLKYHLKRHTGIKAFTCLYCGKNFTANSNLNAHIRNVHSDHKSFGCPECEETFASKDHLNKHQRSRHRQERSFVCSDCGKAYFQRSHLNEHVAACHREYRYRCNICNNSYAARGSLKRHQLQKHLLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092300;
90% Identity: -
80% Identity: -