Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:293388-295379[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0019 0.11 12.3 1.5 1 23 253 275 253 275 0.98

2 11 0.01 0.59 10.0 0.5 1 22 279 300 279 303 0.91

3 11 0.069 4.1 7.3 0.1 1 23 335 358 335 358 0.94

4 11 7.1e-08 4.2e-06 26.2 1.3 1 23 365 387 365 387 0.98

5 11 7.7e-05 0.0046 16.6 2.9 1 23 393 415 393 415 0.97

6 11 2.8e-05 0.0016 18.0 0.4 1 23 422 444 422 444 0.98

7 11 8.7e-08 5.1e-06 25.9 2.5 1 23 450 472 450 472 0.99

8 11 0.0016 0.092 12.5 1.1 1 23 478 500 478 500 0.98

9 11 0.00041 0.024 14.3 0.4 3 23 508 528 507 528 0.99

10 11 9.1e-06 0.00054 19.5 0.5 3 23 536 556 534 556 0.98

11 11 1.5e-08 8.9e-07 28.3 0.6 1 23 562 585 562 585 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0019	0.11	12.3	1.5	1	23	253	275	253	275	0.98
2	11	0.01	0.59	10.0	0.5	1	22	279	300	279	303	0.91
3	11	0.069	4.1	7.3	0.1	1	23	335	358	335	358	0.94
4	11	7.1e-08	4.2e-06	26.2	1.3	1	23	365	387	365	387	0.98
5	11	7.7e-05	0.0046	16.6	2.9	1	23	393	415	393	415	0.97
6	11	2.8e-05	0.0016	18.0	0.4	1	23	422	444	422	444	0.98
7	11	8.7e-08	5.1e-06	25.9	2.5	1	23	450	472	450	472	0.99
8	11	0.0016	0.092	12.5	1.1	1	23	478	500	478	500	0.98
9	11	0.00041	0.024	14.3	0.4	3	23	508	528	507	528	0.99
10	11	9.1e-06	0.00054	19.5	0.5	3	23	536	556	534	556	0.98
11	11	1.5e-08	8.9e-07	28.3	0.6	1	23	562	585	562	585	0.97

Sequence Information

Coding Sequence: ATGTCGGAAATCGCGAATTTCGCGGATTATTCGTCGGGAAATGTGCTGCTTTACGATTCCCGGGTGTGCCGGTTGTGCGGGGAAGAGAACGAGAATGGACTGCCGTTGTTCCGGAATGGTACGGTTAAGGGTGTGTGCGAGATCAGCCAGCTCATCAACCGGTATTTGCCGGTAGCGGTTCAGGATGATGGTATCTCGCCACGGTGGATTTGCCCCGGATGCCACATACAGCTGGAATCGACGGCCCAGTTCTTCGAGATGATCCTGAAAGGGCAACAGTTGGTGGAACAGTTACTGTTCAGAGAAATCGAGAGGGAGAAAGAGCGCGAATTGGCGGTCGCTAGCAAGAATACCACCGTTGCCCGAGTGGAAGATCTAGGTCCACTATACGATACTCTCCTCGATCAAGCCAAGTGGAATGAGCTGTTTAGCAAAGCAGAGATATCCGTCACAGCATGCGTTGGAAACGATCTTCCACCGCTCGAGCTTCACGAGCTCGAGGACTTGCTTAAACCCACTAATGACAAAGACACCAGACAAGATCAGGTACCGTTTATCGCAGAAGAGGAGTCTCCGGTAAGGGAACCTTCAACGGATGAAGCGAATGAACTAGGGGAGAAGGATTGGATCGTTAACTCGGATGTTTCAAAGGCCGGTGGACGGTTGATAGGATTCGTGCAGAATCACAATGCCACCGATATTGGTAGTTTGGTAGTGGTCGAATCGACGACCGGATCATCGCGCACCCAGGCCAAGTTCATCTGCGATATTTGTGCCGAGAGTTTCGCACACGAGCGGCGCTATGTTCGGCACCGCAAAACGCATGCCGTTCTGTTCGAGTGTTCCGATTGTTTGGTGAAGTTCGGCACAACCGATAAGCTGAAGCTGCATCAACAACAGAACGCTCATCGTGGGCAGGGGATAGTGGATGGAATTCAATTCAATAAGAAGAAGGCACAGCGAGTACAGTCCGTGAGTCACGGGACGGAGAAAGTGGATCAGTACGCTTGTGATAATTGTGATAATACGTTCCCGGAGCTGCAGACGGTGCTGAAACATGAAGAAACGGTGCACGTGAGTGAAAACAGAACGTACGTTTGTAGTGCTTGTGGTAAGTCCTTCCGGCAGAAGGATCTTTTAAAACGCCATCAGAGCACCCACACCGAGGGGCGTCCCCATCGGTGTACGGTGTGTGAAGCAGCGTTCAAAACACGGTCGACGCTCTCGAAGCATACCAAATTACACGACGCGGAAGTGAAGCGTTTCCCGTGCACCCTGTGCGACCTGCAGTTCCGATACAAGGCCGGCCTCAAGCAgcacttgaacgtgcacgcgggcgtgaaaccgttccagtgtcagtattgcgagagacgattctcccagcgcggcaacctgaaggaacatttgcgaacacattcgggtgataaaccgttttcgtgcgattcctgtgaggccaggttttccaccagttcccagcagcggatgcacgtcatgcgccacaacagtgcgcgaccgcatgggtgtgaactgtgtagtaaaacgtttatcgcgctcgaggcctacaaaacgcatatgcgacgtcatcggaacgagaaaccgttcggttgcagcgattgtccgcgatcgtttttcgaacggtgggccttgcgcaagcacatccgtacgcacacgctagagaaaccgtacacctgcaagtactgtgggaaggcgttctcggactcgtcgaacatgacacgACACGTTGCCACCATCCATGGCGGCGAGAGAAAAGGAGGCAAGGTCGAAAGCAGCGAAGAACCACCGGAACCGGCTGACCAGGCTACTGTGATGACGATGAACAACGAGGTAGACACAATGGTGACTGCTCTTCCTGAGGATGAGTTACTATCGTTGGAATCTGTGGTGCTAATGAATGATCAGTAA
Protein Sequence: MSEIANFADYSSGNVLLYDSRVCRLCGEENENGLPLFRNGTVKGVCEISQLINRYLPVAVQDDGISPRWICPGCHIQLESTAQFFEMILKGQQLVEQLLFREIEREKERELAVASKNTTVARVEDLGPLYDTLLDQAKWNELFSKAEISVTACVGNDLPPLELHELEDLLKPTNDKDTRQDQVPFIAEEESPVREPSTDEANELGEKDWIVNSDVSKAGGRLIGFVQNHNATDIGSLVVVESTTGSSRTQAKFICDICAESFAHERRYVRHRKTHAVLFECSDCLVKFGTTDKLKLHQQQNAHRGQGIVDGIQFNKKKAQRVQSVSHGTEKVDQYACDNCDNTFPELQTVLKHEETVHVSENRTYVCSACGKSFRQKDLLKRHQSTHTEGRPHRCTVCEAAFKTRSTLSKHTKLHDAEVKRFPCTLCDLQFRYKAGLKQHLNVHAGVKPFQCQYCERRFSQRGNLKEHLRTHSGDKPFSCDSCEARFSTSSQQRMHVMRHNSARPHGCELCSKTFIALEAYKTHMRRHRNEKPFGCSDCPRSFFERWALRKHIRTHTLEKPYTCKYCGKAFSDSSNMTRHVATIHGGERKGGKVESSEEPPEPADQATVMTMNNEVDTMVTALPEDELLSLESVVLMNDQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092301;
90% Identity: -
80% Identity: -