Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:13288-17675[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.033 2 8.3 0.5 1 23 10 33 10 33 0.98

2 14 3.8e-05 0.0022 17.6 0.3 3 23 55 76 53 76 0.93

3 14 0.023 1.3 8.9 3.0 1 23 82 105 82 105 0.91

4 14 3.7e-05 0.0022 17.6 0.6 1 23 312 334 312 334 0.98

5 14 1.3e-05 0.00075 19.1 0.3 1 23 340 362 340 362 0.99

6 14 0.01 0.59 10.0 3.9 1 23 460 482 460 482 0.98

7 14 2.1e-05 0.0012 18.4 0.8 1 23 488 510 488 510 0.99

8 14 1.1e-05 0.00064 19.3 0.1 1 23 621 643 621 643 0.95

9 14 0.00039 0.023 14.4 1.5 1 22 649 670 649 673 0.90

10 14 3.7e-07 2.2e-05 23.9 0.8 1 23 844 866 844 866 0.99

11 14 4.7e-07 2.8e-05 23.6 1.8 1 23 872 894 872 894 0.99

12 14 0.0005 0.03 14.1 2.9 1 23 1158 1180 1158 1180 0.98

13 14 1e-06 6.1e-05 22.5 2.6 1 23 1186 1208 1186 1208 0.99

14 14 0.03 1.8 8.5 2.2 2 23 1219 1241 1218 1241 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.033	2	8.3	0.5	1	23	10	33	10	33	0.98
2	14	3.8e-05	0.0022	17.6	0.3	3	23	55	76	53	76	0.93
3	14	0.023	1.3	8.9	3.0	1	23	82	105	82	105	0.91
4	14	3.7e-05	0.0022	17.6	0.6	1	23	312	334	312	334	0.98
5	14	1.3e-05	0.00075	19.1	0.3	1	23	340	362	340	362	0.99
6	14	0.01	0.59	10.0	3.9	1	23	460	482	460	482	0.98
7	14	2.1e-05	0.0012	18.4	0.8	1	23	488	510	488	510	0.99
8	14	1.1e-05	0.00064	19.3	0.1	1	23	621	643	621	643	0.95
9	14	0.00039	0.023	14.4	1.5	1	22	649	670	649	673	0.90
10	14	3.7e-07	2.2e-05	23.9	0.8	1	23	844	866	844	866	0.99
11	14	4.7e-07	2.8e-05	23.6	1.8	1	23	872	894	872	894	0.99
12	14	0.0005	0.03	14.1	2.9	1	23	1158	1180	1158	1180	0.98
13	14	1e-06	6.1e-05	22.5	2.6	1	23	1186	1208	1186	1208	0.99
14	14	0.03	1.8	8.5	2.2	2	23	1219	1241	1218	1241	0.94

Sequence Information

Coding Sequence: ATGCGTACACACGAGAAAAGCAATTCCTTCGAGTGTAAGCTGTGTTTCAGCATTTTCGCCTCGGATCCGGCCTTCGCTCATCACATTCGAACCGAGCACGCCGGTATGGGGCTTGCCGATGCCCTACCACCGGTACCAGAATCGGAAGCGAGCCGAGTCATCTGCACGTATTGTGATCGGACGTTCGCGGATGCGGATCAACTCGAGGATCATCTGCACCAGCAGCATCTCGGTGTGCGGCCGTTCAAGTGTAACATGTGCCCGAAAGCGTTTATCCGGATGGATTTTCTGCAGTGCCACTACGCCAAGTACCACAACTTTCATCGGCTCAGCATGATGGGGATGggtgatggtattggcggtggtggtggtggtggtggtggtggtggcgatggcgatagaggaggattcggtggccgaggtggaagcggtggtggaATGAATCATCCGCTGGATCCAATCGATCGGGCTGTTCAACGTGCGGCTCTGTGGAACAGTGGATTTCTTGCCGGCAACCAAGGATCCCAAGGAAGGCAGGACTCGTCGACGGGCATACCAAGGTTGGCGGTACGGAAAATGGAAGATTTGCTCGATGGTCCGAGAAGAATCGTTTCCGGTTCCATGGTCCCGGGGCTTTACTCGCGCAGAACATCGCATACGACGGGCACGACGATTGGCAGCAGTTCGAGCGAAGATAATGATGAGGACGACGATGACGATGACCTGAAGCTGGTGGTAGTGATGGAAGATGATGATGGCGATGATGAGGGTACGGAGAGCAATTTGCAACGGAAGCGGAAGCTCACGAACGGTGCTGCGCTCAGTGCGCGATCGACAAAGAAGAAGAAGAGAGCATCGATCGGTACTGAGGTCGCTGGTGGGCCACAGTTACCAGTGGCCACCATTCCACCGGTCGAAGAAGAAACTGGCAAGCATCGGTGTCCGGTTTGTGAGCGACGGTTTATCCATGAACCGGAACTGATGGCACACGTACGCGTACATCCTGATCTTCCCACCTACAAGTGTCCTCTGTGTGAGCTAACATTCATCGGATCGGACTATCTGAAGGCGCATCTTAAGAAGCATGTTGTCGGTGATGGTGAAGATCCGAATGCACCCGGTGCGATCGATTTGAAAGCGCCCGCAGAGACGGTTTCGGCACCAGTTCCAGCACCTTCATCTCGAACATCCACTACGTCACCTGCACCGCCTGCTTTGATCTCCAGCAAATTCCCTAAAATCGTGTCGAAAGTACCTTCAACGGGCATCTCATTATTGAAGCCACTAGAAGAACGGAAGCCACCTGAGcagcagcatcagcaacaacagcagcatcaACCATCCCAAGAGTATTGCACCAAAACGGCCGATGGCAAGTTCAAGTGTACCGTATGCGAACGGCTCTTTTCGCACCAGCAAACGGTGCGGATCCACTTCCGGAACCATACGAACGAGAAACCATACAAGTGTGCTTTCTGCACGGAATCGTACATCCGGTCAGACTATCTCGAGCGGCACCTAAAGGTGCACTTCAAGGATGGCGTTCTGCCAGCGAACGCGATCGCCAGTATGGCCGCGGCCGCAGCTCGTGAAGCGGCAGCCGCCGTAGCCCTCTCGAACGGTACTGGTGGAAGCCAACGGTCGTCTCTCCCGTCGTCACCAACACCACCACCATTACTTACATTGACGACCGCTGCGACAACTCCCGCGgcagcagcagcagcagcaACAACATTGGCCGTGAAGGAGGATGTGAAGCGGGAGGTAACGCCATCGACGACACCAACACCGAAACCACTGATCGGACGAGCTGGGCTCGCACCGGAGAACTATCACTTTACCGAGTCGAACGATGGACAGTTTGTGTGTAAGATCTGTGACAAGGTGTTTGCGCAGGTGGCATCGTTACGGAAGCACGCCCTGGCGCACAACGAGGAGAAACCGTTCTACTGTGAGGTATGCGATCGATCGTTCATTCGTGTCGACTACCTGAAGGAGCACTTCAAATCGAAGCGTCACCTGCAGCTGGTTTCGGAAGGGCTGATCGGGTTGCGGGAGGTCGAAGAAGACGATTCGACCATGGATGGTGGCGGTGGATCGTCCCGATCCCGTACTGCTTCATCGAAGCGTCGTAGCAAGCCGGCCGATAAGAGGAAACCCACTGATGCGCTGGCAGTCGCTAGTGAGGTCAGCGTAGATGCGATCCATCcgacactagtggcggccaactgtagcaatagccgttgcagcagcactagtagcacgggcagtagcggcagcagcagtagcagtagtagtagcggtggtagcataagccgtagcagtagcgcttgcGAGGTAGCGATCATCGATCACACTCCTACGAAGTTGGTCGTCAATAGTAACAGCAACAGCAACGGTGCGGTACAAACGCCACCCTCGGCAGGCGAACAACATCCCCAGCAGCTGCTGCAGAAGACGACACTCGGATCAGCGGGGACAACGCCCGAGTTTCATCGGTCCGATTACGAGCGTACGTCCGATGGGCGgtacaagtgtaatcagtgcgataaaacgttcgtcaccgcggtcacactgaagatgcacatccggttgcacacgggcgagaaaccgtacaagtgcgacaagtgcgataaggcgttcattcggtctgattatctgaagacgcacgagaaaacgcaccggcagcagTCGTTCCTTAGTTTGCTGGCGCTGACCTCGAAGGAACCGAGCACGGCCTCCGAGGCGGGCGATGATTCAGATGTGGCTGAGGGAAGAACGGGCGTTACGGTGGGGAGCATCGATGAACATCGCCACGAAGCGGTCAGCGGCCGATCCTCGATGGCAGCGGACAATACTGATGGGGAGCAGCAGCGGCTTTCAGCGGCCATGAAGTCGATGATCAAGCGAGAAGGGCAGCGCGATGGAGGCgaggagcaagaagaggacgaagatgaggaggacgaagaggaCGGCGATCCTTCGgaagacagtgaagaagacgaagaagaagacgaggaagaagaggaggaTGGTGGTGCGCAGGTCATCAAAGTAATGGTCAAAGAGGCGAGTTGCTCGGAAAGCGAAAATGAGGACGATGTGGACGAGGAAGATGAGGAGGAAGGCACGGGTGAGGAAGCAGAAGAACGGATCAGCAGCCGAAGCAAAAAGCATTTCAACGCCAGCAACAGTACAATTGATCTTCCAGATCGCGAATCAGCCAATGCCAGCTTGCTGCAGCGTAATCGAGCACAGCCACAATCGGGCCGCGAGGTAGCGGGAGCAAAGGAGGCACGGGCCAGTTTCCACAGTAACCGCAGCATTGTGAGTGGCGGAGAAAGTAGCAACAATGGTTACGATGATCACGACGAGGATGACAGTGCGTCGCAGACGAGCGACGGGCAACGACTGGCGAATGGTGGTGGCGGTAGTTACTGGGCGCAAAGCGGTTCTCCAAGGCCGGACAAGCACAGTTGCCCCACGTGCCACAAGCTGTTTGCGTGGCCGAAATCCCTGAAGATCcatatgcgcacgcacaccggcgagaagccgtaccggtgcgacgtgtgtggcaagtgctttggccgatcggacagtttgcgaggccacaaacggacgcactccgaggagcaacagcacCAGCGGATTGTACAGTGCCATCTGTGTGATTTGTGTTGTACCAGTGGCGAAGAGCTGGTGCAGCATCAGCTCGCGGCCCACGGTATTGAACCGCTAGAGTGCTAG
Protein Sequence: MRTHEKSNSFECKLCFSIFASDPAFAHHIRTEHAGMGLADALPPVPESEASRVICTYCDRTFADADQLEDHLHQQHLGVRPFKCNMCPKAFIRMDFLQCHYAKYHNFHRLSMMGMGDGIGGGGGGGGGGGDGDRGGFGGRGGSGGGMNHPLDPIDRAVQRAALWNSGFLAGNQGSQGRQDSSTGIPRLAVRKMEDLLDGPRRIVSGSMVPGLYSRRTSHTTGTTIGSSSSEDNDEDDDDDDLKLVVVMEDDDGDDEGTESNLQRKRKLTNGAALSARSTKKKKRASIGTEVAGGPQLPVATIPPVEEETGKHRCPVCERRFIHEPELMAHVRVHPDLPTYKCPLCELTFIGSDYLKAHLKKHVVGDGEDPNAPGAIDLKAPAETVSAPVPAPSSRTSTTSPAPPALISSKFPKIVSKVPSTGISLLKPLEERKPPEQQHQQQQQHQPSQEYCTKTADGKFKCTVCERLFSHQQTVRIHFRNHTNEKPYKCAFCTESYIRSDYLERHLKVHFKDGVLPANAIASMAAAAAREAAAAVALSNGTGGSQRSSLPSSPTPPPLLTLTTAATTPAAAAAAATTLAVKEDVKREVTPSTTPTPKPLIGRAGLAPENYHFTESNDGQFVCKICDKVFAQVASLRKHALAHNEEKPFYCEVCDRSFIRVDYLKEHFKSKRHLQLVSEGLIGLREVEEDDSTMDGGGGSSRSRTASSKRRSKPADKRKPTDALAVASEVSVDAIHPTLVAANCSNSRCSSTSSTGSSGSSSSSSSSGGSISRSSSACEVAIIDHTPTKLVVNSNSNSNGAVQTPPSAGEQHPQQLLQKTTLGSAGTTPEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKTHRQQSFLSLLALTSKEPSTASEAGDDSDVAEGRTGVTVGSIDEHRHEAVSGRSSMAADNTDGEQQRLSAAMKSMIKREGQRDGGEEQEEDEDEEDEEDGDPSEDSEEDEEEDEEEEEDGGAQVIKVMVKEASCSESENEDDVDEEDEEEGTGEEAEERISSRSKKHFNASNSTIDLPDRESANASLLQRNRAQPQSGREVAGAKEARASFHSNRSIVSGGESSNNGYDDHDEDDSASQTSDGQRLANGGGGSYWAQSGSPRPDKHSCPTCHKLFAWPKSLKIHMRTHTGEKPYRCDVCGKCFGRSDSLRGHKRTHSEEQQHQRIVQCHLCDLCCTSGEELVQHQLAAHGIEPLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092941;
90% Identity: -
80% Identity: -