Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:23066-26566[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.11 6.7 6.6 0.2 6 23 245 262 245 262 0.96

2 19 2.7e-05 0.0016 18.1 0.3 2 23 267 289 266 289 0.96

3 19 0.00022 0.013 15.2 1.3 1 23 297 319 297 319 0.97

4 19 0.00047 0.028 14.1 1.5 2 23 323 345 322 345 0.93

5 19 0.0002 0.012 15.3 0.4 3 23 353 373 351 373 0.96

6 19 0.00014 0.0083 15.8 1.4 2 23 383 405 382 405 0.95

7 19 0.0044 0.26 11.1 1.3 1 23 412 435 412 435 0.97

8 19 6.2e-08 3.7e-06 26.4 1.8 1 23 440 462 440 462 0.98

9 19 0.00025 0.015 15.0 1.5 1 23 468 491 468 491 0.96

10 19 0.087 5.1 7.0 0.3 3 23 692 713 690 713 0.95

11 19 0.089 5.3 7.0 0.2 6 23 722 739 722 739 0.97

12 19 5.8e-05 0.0035 17.0 1.5 2 23 744 766 743 766 0.96

13 19 0.0072 0.43 10.4 6.1 1 23 774 796 774 796 0.97

14 19 0.00019 0.011 15.4 0.5 2 23 800 822 800 822 0.92

15 19 6.2e-06 0.00037 20.1 0.7 1 23 828 850 828 850 0.96

16 19 0.0043 0.25 11.1 4.4 2 23 860 882 859 882 0.95

17 19 0.017 1 9.2 1.0 1 23 889 912 889 912 0.97

18 19 4e-06 0.00024 20.7 1.3 1 23 917 939 917 939 0.98

19 19 0.0038 0.22 11.3 1.8 1 23 945 968 945 968 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.11	6.7	6.6	0.2	6	23	245	262	245	262	0.96
2	19	2.7e-05	0.0016	18.1	0.3	2	23	267	289	266	289	0.96
3	19	0.00022	0.013	15.2	1.3	1	23	297	319	297	319	0.97
4	19	0.00047	0.028	14.1	1.5	2	23	323	345	322	345	0.93
5	19	0.0002	0.012	15.3	0.4	3	23	353	373	351	373	0.96
6	19	0.00014	0.0083	15.8	1.4	2	23	383	405	382	405	0.95
7	19	0.0044	0.26	11.1	1.3	1	23	412	435	412	435	0.97
8	19	6.2e-08	3.7e-06	26.4	1.8	1	23	440	462	440	462	0.98
9	19	0.00025	0.015	15.0	1.5	1	23	468	491	468	491	0.96
10	19	0.087	5.1	7.0	0.3	3	23	692	713	690	713	0.95
11	19	0.089	5.3	7.0	0.2	6	23	722	739	722	739	0.97
12	19	5.8e-05	0.0035	17.0	1.5	2	23	744	766	743	766	0.96
13	19	0.0072	0.43	10.4	6.1	1	23	774	796	774	796	0.97
14	19	0.00019	0.011	15.4	0.5	2	23	800	822	800	822	0.92
15	19	6.2e-06	0.00037	20.1	0.7	1	23	828	850	828	850	0.96
16	19	0.0043	0.25	11.1	4.4	2	23	860	882	859	882	0.95
17	19	0.017	1	9.2	1.0	1	23	889	912	889	912	0.97
18	19	4e-06	0.00024	20.7	1.3	1	23	917	939	917	939	0.98
19	19	0.0038	0.22	11.3	1.8	1	23	945	968	945	968	0.96

Sequence Information

Coding Sequence: ATGAAAGAAAAGTGTCGATTATGTTTAACTCTTTTGGAGTGTAGTAACTCTATTTCACTGTCGGATTCCGAATTTTATATGAAACTAGCGACGTTGTTCCAGTTCAATATACTCGTCGATAATGCTCTGCCGAATCAAGTTTGCTCCGTATGCCAATCGTCGGTGAACTCGTTCTACACCTTTCACCAGGATGTGGAAGCCAATCAAATGCTACTGCTGGCTCTACAGAACGACAAAGATCCGATTGCCAGCTTCCTTCCCGAACCCAGAGTAGAGGAGTGTGTCGTCGAAATCCTAGCGGAAACAGCACACAATGGTGACGATGATGATGATGACGAGAATAGTCCATCACAACCGGTAGAAGACGAACAGGATGTGGAGATCTACAACAATGACAACAGCTTGGATGATGAAGGTGGTGGCAATGATGATAAAGGGTTCGCGAGTGAAGACGATGAAAGGAGTGAAAAAGTACATTCAAAGACTGATGATGAAGCAACAAGCCAGCCAGAGGTGGTGGCTGTAGCACGTGAGGGCCAAGAGGAGTTGAAGCCACGGCGGAGAGGACGCCCGCCAGGAAAGCGTAATCGTAAGAAAACCCTCAGCCCGGTGGAGAGACCGAAACCAAGGAAGCAAAACAACGTTAACGAAAAGGAAGAACGGATTGCGGACTTTGTGAAGTTGCAGAATCACTATCGTGAAGCCCATGGCACTGCGGGGTACGTGAGATGCTGCAATAAACAGTTCTTTCGGCGGTATCTTCTGCTCGACCACATTGCAGCCCACATTGGGACGATACGGTGCGAAATATGCCAGAAGAGCTACAAATCAAGCCGCTACTTGGCGCTTCACATGGCCAAAGCGCACGGCAGCGAAGAGGATCGGCCATATAAATGCGAAGTGTGTCAGCTTTCCTTTCCAAAGACGTATCTCCTGAAAACGCACCAGACGTTGCACGTCCGAAAACAGTGCCACTTGTGTAATAAGGTGCTGTCGAGCCAACAATCGCTGAGGGTACACTTAGCACAGATGCACAGCGACGATAACCAGCAGATATGTGCCACCTGCGGAAAACTGTTTCGCACGAAGCAGGCCATGGAGAGGCACATCAAGGAGCATCGGGGGGAGCAGCTGGTAGATCGCATGCAATGCGAGTACTGCAAGAAGTGGTTCAACGGGAAGTACAATCTCCGTAAGCATATCCGTTTCATCCACAACGAGGATGGACAGGTGTTCCGGTGCGATATCTGCCAGCACGAAAGCCCCAATAGCCGAGCGCTGCAGAATCACAAACAGCGCGTACACGTGGAGGAGAAGTTCGAGTGTACCtactgtggcaaacggttcaaacggcaaaccagccttcgagagcacatggcctctcacaccggtaaaccactctattcctgcgaagtctgtggcatcaccttcaactcgaaagccaaccGTTTTAGCCACCGCAAAAATAAGCATCCGGTCGAATGGGCAGCTAACAAGCGGTTAAAGGAACAGAGGGAGTTGAATGAAACGGATCCTGGACAGGCTTGCCAACCGTGCCACTCGTTGGTGTCCCAGTTCTATGAGTTTAGCCTTCAGGTGGAGGAAAACCAGCAACAGCTATGGACCCAGCACAGGGAAGGCAAAATCGAGGATGTGAAAGTGGAACTTGATACCGAGAACCACTTGTTCTATCATGTGGACGTGGATGATCTACCACCGGCGTCCGTGAAGCAGGAACTTGCGGAGCACTGTGGAGACAACGATGGCGATATCGGTGATGAGGATAATGACGACAAGAATGATTCTGATTATCTCCCCAAAACAGAGGATCCTCAAATACCGGACGGACACGATGGGGAGGAAGATGTTGCGACTATTGTCGTTGCGAATGTCAGGAAAACGAAAAGAATCAAGCTTAGAAAACGTCACCCTCGCATGGCAAAGGCTGATAAACCTATCCCTCAGCCGGAACCTGAAACAGAAATGGATCCTGAAACGGAGAAAGAGGACACTGAGGAGCAGTCGAAACAAAATGAGGACGATCAGCGCATTAAGGAGTTTTATAACCTCGACTGTGAATTATGCTCAGCAAAGCTGGAGAACCTCGCCACTCTACAGTCACATTATCGACGGAAGCATGAAATCAAAGGCTACATTCGGTGCTGCGATAAACTGTTTTATCGCCGATTCCAGCTGCTGGACCACATGGCCGCTCATCAGGGAACGATAAGATGTAAAATATGTAACAAAAGCTACAAAAGCAGCCGATATTTGGCGCTGCACACGATGAAAAGCCACAGCAAGGAGGAAGATCGTCCGTTCAAGTGCACCAAGTGTCGCCAGTCGTTTCACAAAGAGCATCTCCTGAAAGCGCATCAGGCGAATCACTTGTCCGAAAAGTGTCCGATCTGCGAAAAAGTGGTGTCGTCCAAGTACGCACTGAAAACACATGTAGCTCACATGCATGGTAACGATGGTAACCATATTTGTGACGTGTGTGGTAAAGAGTTCCGCACGAAGCAGGCCATGGAGCGGCACATCAACGAGCACCTGGGACTGGAAGTGGTGCAGAAGGTACAGTGTCACGAGTGTAACCGCTGGTTCCACGGCAAGTACAATCTCCGGAAGCACATTCGCTTCATGCATATCGAAGACGGGCAGGTGTTTCGTTGCGAGATCTGCCAGCACGAGAGCCCAAACAGTCGGGCCCTCTTGGATCACAAGAAGCGCGTACACGTGGACGAAAAGTTCGAGTGCGAGTTTTGTGGCAAGCGGTTCAAACGAAAGCTATATCTACGTGAGCACATCGCATCGCACACCGGTAAACCGCTGTACTCCTGCGAAGTTTGCGGGGCTACTTTCAATTCCAATGCAAACTGTTACAACCACCGCAAAATCAGGCATCCCGCTGAATGGGAAGCTCGCAAGCAGGCATTCCTGGCAGCGCAGCTCAAAAGTCCAACCACTGAGCCCAAGAAGGACTCCTAA
Protein Sequence: MKEKCRLCLTLLECSNSISLSDSEFYMKLATLFQFNILVDNALPNQVCSVCQSSVNSFYTFHQDVEANQMLLLALQNDKDPIASFLPEPRVEECVVEILAETAHNGDDDDDDENSPSQPVEDEQDVEIYNNDNSLDDEGGGNDDKGFASEDDERSEKVHSKTDDEATSQPEVVAVAREGQEELKPRRRGRPPGKRNRKKTLSPVERPKPRKQNNVNEKEERIADFVKLQNHYREAHGTAGYVRCCNKQFFRRYLLLDHIAAHIGTIRCEICQKSYKSSRYLALHMAKAHGSEEDRPYKCEVCQLSFPKTYLLKTHQTLHVRKQCHLCNKVLSSQQSLRVHLAQMHSDDNQQICATCGKLFRTKQAMERHIKEHRGEQLVDRMQCEYCKKWFNGKYNLRKHIRFIHNEDGQVFRCDICQHESPNSRALQNHKQRVHVEEKFECTYCGKRFKRQTSLREHMASHTGKPLYSCEVCGITFNSKANRFSHRKNKHPVEWAANKRLKEQRELNETDPGQACQPCHSLVSQFYEFSLQVEENQQQLWTQHREGKIEDVKVELDTENHLFYHVDVDDLPPASVKQELAEHCGDNDGDIGDEDNDDKNDSDYLPKTEDPQIPDGHDGEEDVATIVVANVRKTKRIKLRKRHPRMAKADKPIPQPEPETEMDPETEKEDTEEQSKQNEDDQRIKEFYNLDCELCSAKLENLATLQSHYRRKHEIKGYIRCCDKLFYRRFQLLDHMAAHQGTIRCKICNKSYKSSRYLALHTMKSHSKEEDRPFKCTKCRQSFHKEHLLKAHQANHLSEKCPICEKVVSSKYALKTHVAHMHGNDGNHICDVCGKEFRTKQAMERHINEHLGLEVVQKVQCHECNRWFHGKYNLRKHIRFMHIEDGQVFRCEICQHESPNSRALLDHKKRVHVDEKFECEFCGKRFKRKLYLREHIASHTGKPLYSCEVCGATFNSNANCYNHRKIRHPAEWEARKQAFLAAQLKSPTTEPKKDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -