Basic Information

Insect: Anopheles culicifacies
Gene Symbol: BCL11B
Assembly: GCA_000473375.1
Location: AXCM01001379:9864-26492[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 8.3 4.8e+02 1.2 0.1 2 11 16 25 15 28 0.86

2 7 0.61 36 4.8 2.6 1 23 248 271 248 271 0.95

3 7 4.9e-07 2.9e-05 24.0 2.7 1 23 705 727 705 727 0.99

4 7 0.029 1.7 9.0 3.7 1 23 733 756 733 756 0.97

5 7 1e-06 6e-05 23.0 3.2 2 23 1015 1036 1014 1036 0.97

6 7 1.4e-05 0.00079 19.4 3.3 1 23 1042 1064 1042 1064 0.99

7 7 8.8e-05 0.0051 16.9 0.4 1 22 1072 1093 1072 1093 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	8.3	4.8e+02	1.2	0.1	2	11	16	25	15	28	0.86
2	7	0.61	36	4.8	2.6	1	23	248	271	248	271	0.95
3	7	4.9e-07	2.9e-05	24.0	2.7	1	23	705	727	705	727	0.99
4	7	0.029	1.7	9.0	3.7	1	23	733	756	733	756	0.97
5	7	1e-06	6e-05	23.0	3.2	2	23	1015	1036	1014	1036	0.97
6	7	1.4e-05	0.00079	19.4	3.3	1	23	1042	1064	1042	1064	0.99
7	7	8.8e-05	0.0051	16.9	0.4	1	22	1072	1093	1072	1093	0.97

Sequence Information

Coding Sequence: ATGGATTCCGAAACGGGAGATTCGGACGGCACGCAGGATATCCTTACATGCGGGTCGTGTCAGAAAACGTTCGCCCTCTCCGACATCGTGCGGTTCATCCAGCACAAAGTGCTCCAGTGTAACAAGGAAAACTATGGCCAGTGTTTCACGCAAGCCGGTGGAACCGATCGTGATTCGGACGATGGCCGTCGGTTAATGTTGACTACCAGCAACACCAGCAGCAGCATAACGACAAGACGTGCCTCCATGCCGAATGTGTCCTGTCGGGTCAAGCAAATCACCACCACCAGCACCCTCAGCAGCAGTACGACATTCGATCGGGTCCATACACCACCCCCAACCAGCCCGGCGGAACTACTGCGTGACGGAGCATCCAGCACACCGAAACAACTCGGCGATGAACCAGAAAACGCATCCACCCATTGCACGTCACGGGGAGCCAGTCCGCTCGGTTGCACCCTGCACGACAACCACAAACCGTCCGTCCGAATGGCCGAAATCAAGCAGGAACGCATGGACATCGATCCGACGTCGTGCGGCGAGGACGAGTTCGTCAGCCGAAAACCATCCCAGACCGCCCTCCGGAACGGTTCGCACGAGAGCCGTATGAAGGGTGGTTCCGATGCGCCCGAACCCAACAACACCAGCAGTGGACCTCCCGAATGTTCGGCAGCGTTTCGAGAACAAAAGGCACGCACTGCATGTCGCCCAACGCGCCGGGTGACCCCGGAGCCCAGCAACTACGTTTGTTCGACGTGCAAAACCAAGTACCATTCGGCATGGCGGCTGGTGCAACACGTACAGCATGCGCACGGTGTGAAGATTTACGTAGAATCGTTAGCCAGCACAGGCAACCAGGACGGTGGAGCAGCACCAACTGAGGAATCCGATGCGCCGGAGTCGGCTGCCGCTTCCGAGGAAGCAAACGGTCCGGCACATCTGGAGTCACAGAAGCTGACCGACATTAGCGATGAGCCGGAAACAACCGTACCGCGAAGCAGAGGTACAAGCCGAAGCCGTCATGAAGATTCCATGGAGAGGGAAGTAGAACAGCTACATAAGATCCGGTCTCCAGCGCTCAAAGACAAAGAGAGCTCAACTAGCAATGGATTAGAAATGGCATCTGGCGCATCTAGCGAGAACGGTGTGGATGTAGACTCCGATGAGGAGATTGAGGTACGAACGAAGCGTCCGAAACTGACCACCACCACCGTAAGCAACAGTTCCAACGGAAGTCACAGTACGGTTGATCACACCGTAGAAGTAGCTCTGGCACTTACCAGCCCGCAAACATTCACCACCTCCACGGCACAGTCCCTACGGCAATCGAGTACTCCCCAACCTACGACGGCACCCTTCATCGCCAACGCTACTTCACCTTCCCATTCACAACATTCACCTCCAGCGAGCAGTGCAGTTCCAACAACGCCCTCCCTCACTCCTTCGCGCAGTGAATCGACGCAAAGCCTTCCACCAACGTCACTGCGGGCACATCACACGCTACTGCCACCACCGGAACTACACCCGAACCCATTCGGATTGCTTCGAATGCCACCGCATCATCCGCACAGTCCACTGTTCGGTCGAGCGCATCACGACTTTCGCATGGATCACCTAATGTCGGAGCAGTTCCGTAGCCATGGCCTCAACCTTGCTGCTGCAGCCGTTGCGGCAGCGAACCAGCTAAAATCCCACGGCCAACAGTTCAATCCAGCGACTGGGGCAACCGCCTCAGAACGTCCACCCTCGGCTAGTGGAGCCGCCCTAACGCTCACACCTGGCGGTGGTCTGGAACCACACATGGACTACTATTCCCAGCGGTTACGGCAACTCGCCGGTACAACGAGTCCCGGTGCCAACCTTACCTCCAACTCCTCCAACTCTCCTAGTCCCCGCAAGCAACAACACTCACCGTCCCACTTTGCCAGCCCATCACCATCCCAACTGCCACCGACACCGCTCACCAACAACTCGCGGCCACAAAGTCTTACGCCACCGGAGAAGACCGAACTGTTAGGTATGGATGCGGGCATCAGCATCAGCAATACACCCCGGTCCGCTTCGACACCACCAAACAAGCAGTCGATTCAATCCGCCTCCGACAATGCGCTCTACTCGTGTGAGTTCTGCGGCAAGAAGTTCCGCTTCCAGAGCAACCTGCTCGTGCATCGACGGACGCATACGCGCGAACTACCCTTCAAGTGCACAAGCTGTGAGTTCTCGTGTGCGAAGGACTCGAAGCTGAAGCAGCATATGAAGCTGGTCCATGGAAGGCGGCGTTCGTCAGCGGCCATTTCCGAACCGGATTCGGGCGCTAGCAATGTTGACTCGATCAAGAGCGATCCGGACGATACGGATAATGAGCTGATGGAGGATCTGgatgcggacggagacgatcggcgtatgggacacgatggtaccggagatgtcgacgaagacaacggtgaggatgatgacgatgaggaggatgaagacgacgaggatgaggacgatgaggcggaagatCTCAGTATGAGCAGTACTCAGAGTCAGTCCAAGAAGGATGGAAGTGGTGGATCACTGCCAATGTCCACCTCGCTCGTGGGAGAGCTGATGGATAAGTTCGGGCTGTCCAACATTGCCCAGTACTCGGAGGCCTACAAGCAAGCCCTGCAGGAGTCAGGCAATGCGCTTAAGCTGCAGCTAACGAGCAAGGATCGGGACAACAACAACAGCGCCATGGCTATTCCCGGGCTGGCGGAGAAGCTGAACGGATTGCCAACGGCACTTCGGATCAAGCAAGAGCTGGCGAAAAACATGCTCCAGCATCACAACGCTCAGTTGCCGCAGGTTCCGCTGTTCAACCCATTTGAAAACCCCTTCGACGCCTCCAAGCGCATGAAGCTCGAGGGTGGAGATAGTTGGTGGGGTCTGCCAGGTTTACACCGTGGGGACGCACTGTTCGAGGATATGAAACCGGGTCGGGATGGAAGTGTGGGGCGTGGATCTGGTGCCGGTTTGCTACAGCCAATGATGAAGAAGGAGAGCAAACTGCGCAACGacacgtgcgagttctgtggcaaggtgttcaagaactgctccaacttgacggttcaccggcgaagtcacacgggcgagaaaccgtacaagtgtgagctgtgTTCATACGCCTGCGCCCAAAGCTCGAAGCTGACGCGCCACATGAAGACGCACGGGCGGCTCGGCAAGGATGTGTACCGATGCCGCTTCTGCGAGATGCCCTTCAGTGTGCCCTCCACGCTGGAGAAGCACATGCGCAAGTGTGTCGTCAATCAGGGTAagctgcagcagcagcaacagcgagaactgcaacatctccagcaacagcaacaacagcgagaactgcaacaccatcagcaattggccgcccagcagcaacagttagccgcccagcagatggcactcgctgcccatcgcgaccgcgatcatcatcgggagcgagaccgcgaacgagaccgtgaccatcaccatcaccagcagcagcaacaAGGGCCACCACCTGTTTCGATGCTAGCAGCTGCAGCAGCCGCTTCACCTTCGCACGTTGGACCACCGCAACTACCGCCCGGGCTGCTACTGCCACCGTTGCCAGCCGCCGTCGCTGCAGCAGCTGCTGCCGCTGCAGGTGTTTCGGCGGACGATAGTGCATCCTGTTCACCGTCCGGTTCCTCGTCATCTTcagccgccgccacagcagcagcagccgccgcagccgccgcagcTGCTCTCATTAAAGAGGAGGCGGCAACGGCATGA
Protein Sequence: MDSETGDSDGTQDILTCGSCQKTFALSDIVRFIQHKVLQCNKENYGQCFTQAGGTDRDSDDGRRLMLTTSNTSSSITTRRASMPNVSCRVKQITTTSTLSSSTTFDRVHTPPPTSPAELLRDGASSTPKQLGDEPENASTHCTSRGASPLGCTLHDNHKPSVRMAEIKQERMDIDPTSCGEDEFVSRKPSQTALRNGSHESRMKGGSDAPEPNNTSSGPPECSAAFREQKARTACRPTRRVTPEPSNYVCSTCKTKYHSAWRLVQHVQHAHGVKIYVESLASTGNQDGGAAPTEESDAPESAAASEEANGPAHLESQKLTDISDEPETTVPRSRGTSRSRHEDSMEREVEQLHKIRSPALKDKESSTSNGLEMASGASSENGVDVDSDEEIEVRTKRPKLTTTTVSNSSNGSHSTVDHTVEVALALTSPQTFTTSTAQSLRQSSTPQPTTAPFIANATSPSHSQHSPPASSAVPTTPSLTPSRSESTQSLPPTSLRAHHTLLPPPELHPNPFGLLRMPPHHPHSPLFGRAHHDFRMDHLMSEQFRSHGLNLAAAAVAAANQLKSHGQQFNPATGATASERPPSASGAALTLTPGGGLEPHMDYYSQRLRQLAGTTSPGANLTSNSSNSPSPRKQQHSPSHFASPSPSQLPPTPLTNNSRPQSLTPPEKTELLGMDAGISISNTPRSASTPPNKQSIQSASDNALYSCEFCGKKFRFQSNLLVHRRTHTRELPFKCTSCEFSCAKDSKLKQHMKLVHGRRRSSAAISEPDSGASNVDSIKSDPDDTDNELMEDLDADGDDRRMGHDGTGDVDEDNGEDDDDEEDEDDEDEDDEAEDLSMSSTQSQSKKDGSGGSLPMSTSLVGELMDKFGLSNIAQYSEAYKQALQESGNALKLQLTSKDRDNNNSAMAIPGLAEKLNGLPTALRIKQELAKNMLQHHNAQLPQVPLFNPFENPFDASKRMKLEGGDSWWGLPGLHRGDALFEDMKPGRDGSVGRGSGAGLLQPMMKKESKLRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRLGKDVYRCRFCEMPFSVPSTLEKHMRKCVVNQGKLQQQQQRELQHLQQQQQQRELQHHQQLAAQQQQLAAQQMALAAHRDRDHHRERDRERDRDHHHHQQQQQGPPPVSMLAAAAAASPSHVGPPQLPPGLLLPPLPAAVAAAAAAAAGVSADDSASCSPSGSSSSSAAATAAAAAAAAAAALIKEEAATA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105416;
90% Identity: iTF_00105416;
80% Identity: -