Acul001453.1
Basic Information
- Insect
- Anopheles culicifacies
- Gene Symbol
- ZFY
- Assembly
- GCA_000473375.1
- Location
- KI422808:4549-7207[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.017 0.99 9.7 1.0 1 13 292 304 292 317 0.92 2 13 4.1 2.4e+02 2.2 0.2 1 21 320 340 320 345 0.89 3 13 0.0018 0.1 12.8 4.7 1 21 408 428 408 429 0.92 4 13 4.8 2.8e+02 2.0 0.6 1 21 436 456 436 460 0.85 5 13 0.12 7 7.0 6.5 2 23 486 509 485 509 0.91 6 13 0.025 1.5 9.1 0.1 1 21 533 553 533 554 0.94 7 13 0.014 0.79 10.0 0.2 1 23 560 582 560 582 0.98 8 13 9.4e-05 0.0055 16.8 4.4 1 20 588 607 588 610 0.95 9 13 3.8e-06 0.00022 21.2 3.0 1 23 615 638 615 638 0.95 10 13 0.00084 0.049 13.8 0.1 2 23 644 665 643 665 0.96 11 13 0.19 11 6.4 0.6 1 23 671 696 671 696 0.94 12 13 2.9e-05 0.0017 18.4 2.8 1 23 702 724 702 724 0.98 13 13 4.2e-06 0.00024 21.1 0.1 1 21 730 750 730 751 0.96
Sequence Information
- Coding Sequence
- ATGAGTTCTAAACATTGTCGAATATGTTACAAACCAGACCAGGATGATCTAATCTCGGCACGGTTGATGCAGGACAACCTAACGATCGAGGAGATGATCCTGCTCATCACAAGCATCTCAATCTCTAGTGATCGTCGTTTACCGCAAAACATTTGTCTTCAGTGCTTGGATCGATTGAAAATCGCTTACAATCTGCGTCAGCAGTGCATCCAAACGAACGATCGACTGTGTGCGGAATTGGAATACAATCGGATAGTTGAGAAAAAGGAACAAACTAACTCCGAATCCAACACAACATCGGATGGCGAAAACAGGGATGAAATAGTACCGTCAGCTGTTGTTATTGAGATGATCGAAAACGATTCCTATGCGGATTCAATTGTATCGTTTAAGAAACGTAACGACTATACATTGGAGAAACTGCAAATGGTAGAAGCTGAGGAAGGCTCGCTAAAACAGGAGCTTGGCACAATTGTAATAGAAATCGAACCTAAATTGAAGGAATCCGCGAAGAATGAATCATGCATTTTGACGGATTCAAATGCTAATGACGATGAGTTATCATATAATATCGAGTTCAGCGATGCGGAGGAAGAAGAACCAGACGAAAGCGAGATCGATGATGAGTTGGAAGAACAAACGACAGTCAAGTCGACGGAACGCATGCAGAAAGCAAACATACAAAGCGCAATTTGCAGAATCCCCGGTGACAACTTACTGGTTGTGTCACAGGAACAAGGATACCTGATCGTAGAAATGCAGCAGTACCGTTGTTGCTGCTGTGCTGGATTATTCTCCACCGAGCAGCAGTTGGATGAACATCTAGAAAATCGAGACAAAAACGCAGATCCAACGCACGATCGTCACGGGAAGTACGTGTGCGAGTACTGTGGAAAACAATTTACCTACTGGCTGGTGTACATTTGCCACAAGCGCATGCGAGATCAGCGTCAGTTTTACATGTGTACGTTGTGTAATGCGCTGCTAGATTCAAAGAAACGCATGATATCGCACATGCTAATGTCAGACGAGCATGCAAACTATTTCAAACTTTGCCGAGAAAGCATCGCGGATCGATACGAAGCAATAGAACTACCCGGGACACGTTGTTGTTGCTGTAAGAAATATTTTGATGATGACGAGGAGCGACTAGATCATGTTAAGCGAGTGCACGGTCTACCATTGACCGAGAATACCCTCGATACGTCGGCCAAATTATCCCACTGTTGTGTTGAGTGTGGTCGACGGTTTCGTAACGAGCACCACTTGGAATTGCATCTGCAGTACACGGTGGACGTTACGCAGTACTACTGCAAGCTGTGCGAATTTCAAACGTACAATCCAAGGCGCATGGAGTTGCACCTATATAGTGGAATTCATCGCAATACCTTACCGGTATCGGTTCAGCTGAAACCGCTGCAGAACAACGTACCACAAGTATCCCGCTTACGGCACTGCTGTTTTGAAGGGTGTAACAAACATTTCCAGGATGATTCAACCCTAAAGCAGCACATAAACCAGACACACCAGCAAACACTAACAACGAACCGGATTCAGGCaaaaaaaTTAAATCAAATATTGCAATCCGAATTGTACCACGAGTGTAACGTTTGCAGCGTACTGTTCAAGACCATTGGTGCCCTGCAGGCACACCAAGCACGACGCAACCGGGATGACTTTGTTTGCGCAGTCTGTGGCGTTACTAAGCGAACCCGAACGGCGCTACGTGTCCACGAACGATCACACACCGGTGAGCGACCGTTTCAGTGTGAGTATTGCGATAAAACGTTTACCACCAATCGTACTCTCGTTTCGCACCGCAGCTGCCACATCACGGGTCAACATACGTGTGATCTTTGTGGCCATGCATTCAATAGGAAGGAAAACCTAAACCGGCATATTATGCTGAAGCACGGTGAAGCGACGATCCCGTGTGATGTTTGTCCGAAAAAGTTTAAAACCACTGCCGTGCTGAACATACACAAACTTTCGCATACGGGCGAAAAGCGGTTCAAGTGTCGGACGGAATCGTGCGACAAGCGTTACATTACCGTGGCTGACCGACGGCGGCATGAGATGTCGGTCCATACGCTCGAACGACCCCACAAGTGTTCCTACTGCAATGCAGCATTCATCCGGAAGCGCCAGCTGACAATACACGAGCGACGTCACACGGGCGAAAAACCGTTTGTATGTCCGGTCTGTGGGAAAGATTTCGTCGATAGGTACCCATTGCAGAATCATATGCGCAACGTTTGCAAGCAAACGTTAATGGAATGA
- Protein Sequence
- MSSKHCRICYKPDQDDLISARLMQDNLTIEEMILLITSISISSDRRLPQNICLQCLDRLKIAYNLRQQCIQTNDRLCAELEYNRIVEKKEQTNSESNTTSDGENRDEIVPSAVVIEMIENDSYADSIVSFKKRNDYTLEKLQMVEAEEGSLKQELGTIVIEIEPKLKESAKNESCILTDSNANDDELSYNIEFSDAEEEEPDESEIDDELEEQTTVKSTERMQKANIQSAICRIPGDNLLVVSQEQGYLIVEMQQYRCCCCAGLFSTEQQLDEHLENRDKNADPTHDRHGKYVCEYCGKQFTYWLVYICHKRMRDQRQFYMCTLCNALLDSKKRMISHMLMSDEHANYFKLCRESIADRYEAIELPGTRCCCCKKYFDDDEERLDHVKRVHGLPLTENTLDTSAKLSHCCVECGRRFRNEHHLELHLQYTVDVTQYYCKLCEFQTYNPRRMELHLYSGIHRNTLPVSVQLKPLQNNVPQVSRLRHCCFEGCNKHFQDDSTLKQHINQTHQQTLTTNRIQAKKLNQILQSELYHECNVCSVLFKTIGALQAHQARRNRDDFVCAVCGVTKRTRTALRVHERSHTGERPFQCEYCDKTFTTNRTLVSHRSCHITGQHTCDLCGHAFNRKENLNRHIMLKHGEATIPCDVCPKKFKTTAVLNIHKLSHTGEKRFKCRTESCDKRYITVADRRRHEMSVHTLERPHKCSYCNAAFIRKRQLTIHERRHTGEKPFVCPVCGKDFVDRYPLQNHMRNVCKQTLME
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -