Acul011756.1
Basic Information
- Insect
- Anopheles culicifacies
- Gene Symbol
- -
- Assembly
- GCA_000473375.1
- Location
- KI423000:8730-20335[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0062 0.36 11.1 3.7 1 23 359 381 359 381 0.95 2 15 6.9 4e+02 1.5 0.1 3 8 385 390 384 407 0.87 3 15 7.6e-05 0.0044 17.1 2.4 1 23 412 434 412 434 0.95 4 15 1e-05 0.00059 19.8 1.3 1 23 452 476 452 476 0.92 5 15 0.0058 0.34 11.2 1.4 2 23 482 504 481 505 0.94 6 15 0.00031 0.018 15.2 0.2 1 23 530 553 530 553 0.98 7 15 0.011 0.61 10.3 3.2 1 20 560 579 560 582 0.94 8 15 1.6e-05 0.00091 19.3 4.1 1 23 588 613 588 614 0.97 9 15 0.3 18 5.8 0.9 1 23 880 903 880 903 0.94 10 15 0.0084 0.49 10.7 0.2 2 23 921 944 920 944 0.90 11 15 0.38 22 5.5 0.6 3 23 951 972 949 972 0.95 12 15 0.0029 0.17 12.1 0.4 1 23 978 1000 978 1000 0.97 13 15 0.097 5.6 7.3 0.2 3 23 1010 1031 1008 1031 0.95 14 15 0.0092 0.54 10.5 3.7 1 20 1037 1056 1037 1059 0.95 15 15 0.011 0.66 10.3 0.1 1 23 1065 1090 1065 1090 0.94
Sequence Information
- Coding Sequence
- ATGGAAGTGAAAATGCAACATCGGACACGGGCACACATGTTCCAGATACAGGTCAAAGCGTTGATCAAGACGCTGAAATGTCTGCAGTCAGACGATAAATACCAGGCGCTGCTGTTTCTTATCTCGGCCATCAAGTTGTACGTCAAGTTCCTGTACAACGATTGCCAGGAACGGCTCTGCAAGCCAGCAATACTCAAAGAGTTGAACAATATCGAAAATGTGATTGTGGTGAACCTGCTTAAATCGCGAAGCGCACCTCCTTCAGGCTCATCGTTGTCCGTAGCCACAGGCCACACGACAGTGTCATCGTACGGTGATGACATTGTAGGCAAATCCTGCCTCGACATTGACACCAGCACCAGTGTACGCTGTACGGACATATCGCTCGGTAGCGATGGTTTGTTGTTGATGCACCCGCACCGAACGCACGGTTCCCCTCTCGCCCCATGGGACCTTCGGGGGAAGCTGCTGCGGGGCAATCTCTTCGATGGGCTGCCACTAACAGGCAGCGTGAGGCTAGGGCCGGATTATACCAGCAAAGGTGGTTCGTTGCTGAAATCGGGTCAACGGGTGGCAAGTGCGAATCGATGGTTGGGAAATGTGCGGATGAATCGTGCGCTGGTTCGTATGATTGCAAATCACGATTTTAAACTGCTGTTCAACATGTTCGAACAAAGCATCTTCCCCGCGTGGAAAATTTACAAAAATGAACGAATATTTGTTCGGAAACGGCCCGCCCTAACTACAGTAACGGTACGCACCTCGCTTCCCGCCATTTGCTATGGTAGCGGATCGTCACACTCCCCACCTGCAACGTACATCAAGAAGGAGGAGTTCGATTTCGATCCACCGTACTCGATCGCCGACGATCACTGTTTCGAGGAGATCAAGGACGAAGACGACGAGGATCTTTTGCTGATGAAGGAAGACGATTCGATCGACAATTCGAATGAAATCTTCTCGGAGGAGGAATCTTCGACGAATAACACCTCGCTAATGCTATCGTCCGACACCAATACGCTGGATACGAACGATTCGAGTATGGTTTCGCACGAGCGCAACAAGGAACAGGTGTACCAGTGCTTACTATGTGATAAAAGCTATAGGAAACGCAAATCTCTTGTCATCCACTTCAGCCACCATCCGGGATTTTGTCCCGATTGTGGCAAACAGCGAGGAGTAACCTCAGAGGAAATCGTTGAGCACAATCGAATCTATCACAAAAACCGGCCTCACATATGCGAGCACTGCGGCGAAACCTTCACTCGGAATCAACAGTATCAGATACACGTCCAGGGACATTTTATAAGCAAAGATAGGGTAGCGGAGCAAAATTGTAAAAAAACTCACAAGTACAGCTGTAAAACATGCGGTATCGTTTTTAATAATCAGAAATATCTCGAAAAGCACATCCAGAAAACCAACCACCAGGCGGAAGGTTTGGTGTGCGACATTTGTGGTGCAATATTTTGTAACAGTATCAAACTTAGCCAGCATGTAAGCCGAACTCATCACAACGTGTTTACACAGAAAGCTACCTTAGAAAGAAGCATGCTTCTTGCGGGAACAAGTGTTACGGACAAAGCCTACACCTGTGAACAGTGTGGTGCCTCATTTCTGTCCCAACCCTCATTACGAGAGCACATCAAAACATCACATTCCGTTCCGGAAAACAAATTTGAGTGCAACATTTGCAACAAATTGTTCGCCGCCAAACGGTCTCTCAAACGCCATAAACTTTGCCATTCGGATGAGCGCGCCTTCCGCTGTACGGTGGAAAATTGCAAGGAATCGTACAAAAATCAATCGCACCTTGCCCGCCACATGAAGACCGCCCATCACATTGATCCACCCTCGAAACGGTTACAAAAGGCGAAGGCGGCTGCGGCCGCAGCTGCAGCAACCAGCACAGGGATCGTCTCATCAGCCGACCCGAGTTCGACCAGTACGGACTTTATCGCTCACGGTGACGGTGCTACGATGGGTGGTGGATCCTGCGACTCGCTCAAAGGCATTAGCAGCACGTTGAAGAAATCTCTCGGAAGCAGTGAAAAATCGCTCGGTGACAGCAGTACTAACTTTAGCGACAATTTGTCATCGTTTAATTACGAATTTTCGGATACGGCCGCAGGCACGTCAACGCCAGCACTTGCAACGACAATAGGTACGGGTGGTGATGGAGGAACGGGTATAATGCTTACCGGTACCAGCTCGTTAACGGGCAATCGTACGTCAGCATTAACCTGCGCCGTAACTGGTCCTCAAGCGGGTGGTGCGTTTAACGATCCCACCATCAGTTTTGGGACAAATAaacaacaacaaccgcagcagcagcagcaacaacaacaacaCCTCGGTACATGGCAGAATCTCGAATTCGCCTCGGCGACAACGCATCGATCGACAACGCTTCCGGGCGGTGGTATGCAACCGATGCAGGATCCACTAGCAACTGCAGGCGGTAGCTTTATGGACGGTGGACACCACCACATTCAAAACCATCAGAACATGCAGCATCAAGCGCTTCATCACGGGTCAGCATCAATCACGAATCAAATGATCAGCTCTGGCAGCAATTTTATGACCACAAGCAATTTACCAGGCAGCACGAGGAGATTCCCTCTTCCGGAGGGTAATTTCATGTGCGAACATTGCGATGAAACAAACTTCATAAACGCTCAACAGTACCAGCTGCACGTGCAGGACCATTTTGCTGCCAAGGAGGGTAAAGATCATCCGAGCAAAAAGCTGTTACGATTAATCTGTAAAACATGCAACCTGGTGTTCGCCACTGGAGCTCAGCTCGATCGGCACATTCAGAAAACGAATCATCACACGGAGAGTATAGCGTGTGAAATATGTAGTGCAATATTCAACTCCAACTTAAAGGTTTACCAGCACATGTTAAAGTGTCACAAGAATGATATTTGGTTTGCTTGCGAACAATGCTCAAAGGTTTTCATATTGAAACAGGACTATGACAAGCATCAGCTAGTACATCAGACGGTTACAGATCGATCGATCATCTGCGAGCACTGTGCATCGTCCTTCCTTACGCAGGAAGCACTAAAGGAACATATCAAAATAGCCCATTCGATGGACAAAAAATACAAATGCAACATTTGCAACAAACTGTTCGCTGCTCGTCGATCGCTTAAACGCCATAAACTGTGCCACGAAGAGGAGGCAGCATTCCGATGTGTGGTCGAGGGTTGCAAGGATGCGTTCCGAACGGCGGCCAACCTGGCGAAGCACAAAAAGATGGCACACCCTGTGGTCCATTCGGCTGTTTCTGTACCTGCAGGCAATTTGATGTCACATGACCCCATCGTGGATAAGGTCAGTGTAGGCCTTGGCATGCCTTCCGGCGTTAAAATGGTACCATCTGGTGCAATGGTATCGGCAGGAGTTCCCAATGCTCCCGTTGGCGGGGCCACGATGAAGGGAATGGAGAAAGCGTTACACCATCAAGATGTGCCGGGTGTAACAATGTCCCCGGGGGGAGGGCAGGCCAATATGATGGGCCAGCTTGGTACGAATCCACTGATGGCATTAAACTCAGGACCAGGGCTTAAGACAGATGGGCGATCGTCTGCGGGAATTGGCAATCCCGAACAGTCCGTTGCTATGGCGTATCGTATGGGGGAATCGGCGGTCCCCGGAAGCAGTGTCACTGCAACAAATTCCGCCAACATTCCGTACGGCTATGGTCAGATGAACAATGCATTCGATTGGCAAGGCGTTGAAATAGCCAATGCCGAACCAGGCTTAATAAGTGGCTCCGCTGGTCAACCGCAAGGTACGCCAACCAATAGTGGGGCAATGAAAAATGCTGCTAGCAATAAATATTACAACTCGATGCACGATTCTGGATCGTCCGGTACATCGGCAGTTGGTGGTGGCAACGCTGCGACTGGattcctgtcgccacaacaattgcagcatcagtctcctcatcacgcacagcacctgcaccacacgcaacaaactcagcttcagcagcagcagcagcagcaacagcaacagcaacagcaacaacaacaacatgttccacatcatccgcatcatgcgcaaggtggtggtttgcaaagcaaacctgtccaggagcagcatagcactcatcaacagcagcagcaacaTATGATGAACATGAGCAGCCAAGACATGATGGGATATCAGTTGGATTACCGACTTATCAAGTATAGTTTCGAGTTTACCATCGCCTTTAGTCGGTTTATCTCGTACGCCATCTTTTGA
- Protein Sequence
- MEVKMQHRTRAHMFQIQVKALIKTLKCLQSDDKYQALLFLISAIKLYVKFLYNDCQERLCKPAILKELNNIENVIVVNLLKSRSAPPSGSSLSVATGHTTVSSYGDDIVGKSCLDIDTSTSVRCTDISLGSDGLLLMHPHRTHGSPLAPWDLRGKLLRGNLFDGLPLTGSVRLGPDYTSKGGSLLKSGQRVASANRWLGNVRMNRALVRMIANHDFKLLFNMFEQSIFPAWKIYKNERIFVRKRPALTTVTVRTSLPAICYGSGSSHSPPATYIKKEEFDFDPPYSIADDHCFEEIKDEDDEDLLLMKEDDSIDNSNEIFSEEESSTNNTSLMLSSDTNTLDTNDSSMVSHERNKEQVYQCLLCDKSYRKRKSLVIHFSHHPGFCPDCGKQRGVTSEEIVEHNRIYHKNRPHICEHCGETFTRNQQYQIHVQGHFISKDRVAEQNCKKTHKYSCKTCGIVFNNQKYLEKHIQKTNHQAEGLVCDICGAIFCNSIKLSQHVSRTHHNVFTQKATLERSMLLAGTSVTDKAYTCEQCGASFLSQPSLREHIKTSHSVPENKFECNICNKLFAAKRSLKRHKLCHSDERAFRCTVENCKESYKNQSHLARHMKTAHHIDPPSKRLQKAKAAAAAAAATSTGIVSSADPSSTSTDFIAHGDGATMGGGSCDSLKGISSTLKKSLGSSEKSLGDSSTNFSDNLSSFNYEFSDTAAGTSTPALATTIGTGGDGGTGIMLTGTSSLTGNRTSALTCAVTGPQAGGAFNDPTISFGTNKQQQPQQQQQQQQHLGTWQNLEFASATTHRSTTLPGGGMQPMQDPLATAGGSFMDGGHHHIQNHQNMQHQALHHGSASITNQMISSGSNFMTTSNLPGSTRRFPLPEGNFMCEHCDETNFINAQQYQLHVQDHFAAKEGKDHPSKKLLRLICKTCNLVFATGAQLDRHIQKTNHHTESIACEICSAIFNSNLKVYQHMLKCHKNDIWFACEQCSKVFILKQDYDKHQLVHQTVTDRSIICEHCASSFLTQEALKEHIKIAHSMDKKYKCNICNKLFAARRSLKRHKLCHEEEAAFRCVVEGCKDAFRTAANLAKHKKMAHPVVHSAVSVPAGNLMSHDPIVDKVSVGLGMPSGVKMVPSGAMVSAGVPNAPVGGATMKGMEKALHHQDVPGVTMSPGGGQANMMGQLGTNPLMALNSGPGLKTDGRSSAGIGNPEQSVAMAYRMGESAVPGSSVTATNSANIPYGYGQMNNAFDWQGVEIANAEPGLISGSAGQPQGTPTNSGAMKNAASNKYYNSMHDSGSSGTSAVGGGNAATGFLSPQQLQHQSPHHAQHLHHTQQTQLQQQQQQQQQQQQQQQQHVPHHPHHAQGGGLQSKPVQEQHSTHQQQQQHMMNMSSQDMMGYQLDYRLIKYSFEFTIAFSRFISYAIF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -