Acul002595.1
Basic Information
- Insect
- Anopheles culicifacies
- Gene Symbol
- -
- Assembly
- GCA_000473375.1
- Location
- KI422544:17712-20235[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 2.7 1.6e+02 2.8 0.1 3 23 230 253 228 253 0.77 2 12 9.3e-05 0.0054 16.8 1.6 3 23 262 282 260 282 0.95 3 12 3.2 1.9e+02 2.5 0.6 12 23 339 351 336 351 0.83 4 12 0.00084 0.049 13.8 0.5 2 23 359 380 358 380 0.98 5 12 0.037 2.1 8.6 0.1 8 23 452 468 451 468 0.92 6 12 0.0057 0.33 11.2 0.9 2 23 476 497 475 497 0.96 7 12 1.3e-05 0.00077 19.5 0.3 1 23 528 551 528 551 0.96 8 12 0.0037 0.22 11.8 0.5 3 23 558 578 556 578 0.95 9 12 6.6e-07 3.9e-05 23.6 0.4 1 23 583 605 583 605 0.96 10 12 0.0004 0.023 14.8 0.3 2 23 618 640 617 640 0.96 11 12 1.1e-05 0.00061 19.8 1.4 2 20 647 665 647 667 0.94 12 12 5.6e-05 0.0033 17.5 4.6 3 23 676 696 674 696 0.97
Sequence Information
- Coding Sequence
- ATGGATgcagcagcaccagcaccagcaccaCCGATCGATGTTTACGATGTCATCAATCAAAAGGAATGCGGAATATGTCTTACGTTCCGGACGGAACAGATCTGCTTCGACATGTTCATGCCTCGGGAGGACGAACAGAAGGAGATGCCGTATCTGGTCTGGAAGCACGTCGGGCTACAGTTTACGCAGGAAACGGGAAAGCACTATGTCTGTCGGGATTGTGGGAACGCGGTGTACGAGTTTAATCGTTTCTACTTGATGGTGCAGAATGTACACCAGGAAAGGCAGGCGGCGGTGCTCCAGACTAAACAGGAACAGAGCGAAGCATGTAATGCCGTACCGGCGGAAGAACTGCAGGCACCAGGCGTTAACCAAAATGGTCACTATGGGGAGCTGAATTTGATTCCAGCGCCACAGGTAGAAGCCAGCGAGCCCATATTGCAAGATGTTCCCGAGTACACGGTGAAGCCCGAAGCGAATGGTATGCCGAGCCGGGTCGGCCTGGTCGGTGGCAATGGTATGGCGGAGGGTTTGGGGGAACAACAAGGGATGGCATCATACGCGTCGTTGAACGATACGGAACCGGAAAGTAGTCGAATCCGGCCACCGGTTCCCGGTGGCACCCCAAACCGGAAACGTAAGAACCAAGAGATGGACGAGGAAATTATTGACTTCTACAAGCTCATTTGTGATGTGTGTGAGGACCGCATCGAGTACGGTACGATGAAGGAACTAAATCAGCACATGAAACAGATGCACGGTGAAGAATCCGGACGGGTTTGCTGTCCACAGTGTGGTAAAATGTTCCGGACCCGTGTGAAGTTGCTGGAGCACAAGAGTGTACACATGCGCCAAGACACGACATCGGAGGACGACGTGGAAAAGGTACAGTCGGAGCAGATGGACAAAGAAATACTGGATTTTTACAAGCGAATCAGTTGCGAACTGTGTGATACTGCAACTGGTGCCGGTGGCGTTGCCGGAGCCGGTCCACAATCTGGGGTACTGTACGCGACCGTAAAGGAGCTAAACCACCATATGCGATTGGTGCACGGCCAGCCGGCCGGTACAGTAAAGTGTCCGATCTGTGAGAAGAAAATCCGTACGCGACCGAAACTGCTCGAACATAAGCGCATGCATCAGCCAAACGCGCTGCTAGAGGAGGATTCCGGCAAATCGGGTAATCCTGGCGGTGAGCCAGGTCCCGAGCTAACGGAAGAACAGAAGCAGACGCTAGATAGAGAAATTTTCGATTTCTACAAACCAATTATATGCGAGATTTGCGATCCGGAAAAGGCAGCAACCGGTCAAGGAGAATTGGCTGCTGCAAGCGGGCAGGAAGAAACGGCAGAAGAGGTGTACCGATCGCTGAAGCAGCTGAACCAGCACATGCGGACAGTGCACGGGCTTGAATCGGGTACGGTCAAGTGTCAGCTGTGTGCAAAAAAGTTCCGTTCTCGGGTGAAACTGGTCGAGCATAAAGATATGCACGAGAATCCTGAAAGGTTCCGGTGCACCGTGTGCCAAGAGGTACACCAAAACTTAGAGGAGCACATGCAAAACAAGCACCAGGAATGGGAGTTTGCTTGCGAAGAGTGTGGCAAGCGGTTTCCTTTCAAGAACAGACTCACTGCCCACATGGCAAAGGTGCACATGAAGAAGGACATTATCTGTGAGGAATGTAACAAACCATTTACCAAGTTCAGCATCGAGAAACACaaaaaaaCGGTTCACGGTGGTGCGATATTTATATGCGAAAACTGCCCCAAAACGTTCAAGACGCGCGTTTCGCTCGAACGGCATATGGAGGGCCACAATAACGGGGAGCAGCCGGGTTCTGCTGCCACCGTCAGCTGCTCACTGTGCAACTCGGTTCTGAAGGACGAGTACAATCTGAAGGCCCACATGAAACGAATTCACGCCGAACAAACGCCGGCCACGTGCAGCACGTGCGGCAAAACGTTTAAATCGAAGCACAGTCTCAATACGCACATCGCGAACGTGTGCACCAATGGACAGTTCGGCTGCACGCACTGTGGCAAGCAGTTCAAGAAGCGGACAAAATTGAAACAACACATGACGGTTCACGCACGCGGTGCCGACTAA
- Protein Sequence
- MDAAAPAPAPPIDVYDVINQKECGICLTFRTEQICFDMFMPREDEQKEMPYLVWKHVGLQFTQETGKHYVCRDCGNAVYEFNRFYLMVQNVHQERQAAVLQTKQEQSEACNAVPAEELQAPGVNQNGHYGELNLIPAPQVEASEPILQDVPEYTVKPEANGMPSRVGLVGGNGMAEGLGEQQGMASYASLNDTEPESSRIRPPVPGGTPNRKRKNQEMDEEIIDFYKLICDVCEDRIEYGTMKELNQHMKQMHGEESGRVCCPQCGKMFRTRVKLLEHKSVHMRQDTTSEDDVEKVQSEQMDKEILDFYKRISCELCDTATGAGGVAGAGPQSGVLYATVKELNHHMRLVHGQPAGTVKCPICEKKIRTRPKLLEHKRMHQPNALLEEDSGKSGNPGGEPGPELTEEQKQTLDREIFDFYKPIICEICDPEKAATGQGELAAASGQEETAEEVYRSLKQLNQHMRTVHGLESGTVKCQLCAKKFRSRVKLVEHKDMHENPERFRCTVCQEVHQNLEEHMQNKHQEWEFACEECGKRFPFKNRLTAHMAKVHMKKDIICEECNKPFTKFSIEKHKKTVHGGAIFICENCPKTFKTRVSLERHMEGHNNGEQPGSAATVSCSLCNSVLKDEYNLKAHMKRIHAEQTPATCSTCGKTFKSKHSLNTHIANVCTNGQFGCTHCGKQFKKRTKLKQHMTVHARGAD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00101878;
- 90% Identity
- iTF_00101878;
- 80% Identity
- -