Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI422468:51498-53640[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 3.4e-06 0.00019 21.4 0.2 1 23 234 256 234 256 0.98

2 10 0.088 5.1 7.4 0.7 1 21 269 289 269 290 0.93

3 10 0.0028 0.16 12.1 0.2 2 23 316 337 316 337 0.97

4 10 0.14 8.4 6.8 0.0 1 23 341 366 341 366 0.94

5 10 9.3 5.4e+02 1.1 0.2 3 19 374 389 373 392 0.70

6 10 0.00072 0.042 14.0 1.8 1 21 399 419 399 420 0.95

7 10 1.2e-07 7e-06 25.9 1.2 1 23 425 447 425 447 0.98

8 10 4.3e-06 0.00025 21.0 0.4 1 23 453 475 453 475 0.98

9 10 0.0031 0.18 12.0 6.0 1 23 481 503 481 503 0.98

10 10 0.00024 0.014 15.5 5.3 1 23 509 532 509 532 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	3.4e-06	0.00019	21.4	0.2	1	23	234	256	234	256	0.98
2	10	0.088	5.1	7.4	0.7	1	21	269	289	269	290	0.93
3	10	0.0028	0.16	12.1	0.2	2	23	316	337	316	337	0.97
4	10	0.14	8.4	6.8	0.0	1	23	341	366	341	366	0.94
5	10	9.3	5.4e+02	1.1	0.2	3	19	374	389	373	392	0.70
6	10	0.00072	0.042	14.0	1.8	1	21	399	419	399	420	0.95
7	10	1.2e-07	7e-06	25.9	1.2	1	23	425	447	425	447	0.98
8	10	4.3e-06	0.00025	21.0	0.4	1	23	453	475	453	475	0.98
9	10	0.0031	0.18	12.0	6.0	1	23	481	503	481	503	0.98
10	10	0.00024	0.014	15.5	5.3	1	23	509	532	509	532	0.97

Sequence Information

Coding Sequence: ATGGGTGAAGTTTGTTTAGATATCGATCTTCACAAAGTATGTCGAATCTGTTTATCGCAAACAGACACGAACGACATTCTTTTTAACATATTTACGGACGCAATAGTCGACGGCATGTTTGTGACTCTGTGTGAAGTAATCGAAGACTGTGTCGGGATACAGGTTAGCAACACTGCTGAGGCGCCGGACAAGATATGCCAGACTTGCAAATCGATCATATTTCAATTTCACGTGTTTAAACAAAAATGCCATCGTGCTGAAAATTTGTTGCGAACCATGGTGGAACACAGAACACCACGGAGAATCGCTGAAGGAGTGAATGAAATAGATTCAGAAGAAATTAATTACACGGAGCAACAAACCACATTTTACCAACGAGCGGACGAACCGTCTATCTGTCAGGAACCTTCCCCTTCAGTGGAATTCGTTGAAGAAACAATCGAAGAAGAAGTTATGGGTGTTATAATCAATAACAAGGAAGCTTCAAGTTCTGAAGAATGGTACAATTTCATTGCCCAATCACCGGATACCTTTCGTATGTCTAAAGAGGCAAACGTACATAGTCCTAATGGAGTAGGGATGGCTTCCGCAAGTTGTGAAGATAATTTGCACCCCAGTACGATATCAGAGTCTCCCAATTTTGCaaaaaaaTCAACATTTCAGTCTATGATGGATCATAGTTTGAAAGAAAACAATCGTTATGTTTGTGACATATGTGGCAAAGTAATAATCTCCCGATCCCGATTGACGAAACACATGAAACTACACAATGATTCTAAAATTGTTCTAGATCATATGCGTTTCTTTTCCTGTACCTTCTGTGAATATGTGTTCCTGCGGGAAGACAATTTTAATGAACATAATCGAGATTGTGCTGAAAGACCCGCTAAATATGAAAGTGATCACATAAGCAAGAGTCTAGAGAAGGGCAATGTCGGCAGTGGTGTCTGTGGAATCTGTGATGCGAGGTATGACGATATGCTTCATCTGAAACAGCATATAATAACTCATTTGGACAAATTCCCATGCCCATTGGAAGCTTGCGGGTGTGAGTATGCGTCGCTGGCAAGACTGATTATTCACATCAGCACCCAACATGTAGAATACCTTTCACCGAATTGTCCTCACTGTAAGGAGGAAATCGATCGGGTCGATATCAGGCAACATGTGCGACTGTTTTGTAAAGCGAAGCAATATCAATGCACCCACTGTGACAGAAAATTTCTTTCGTGGAAAGCTTTGTCACAGCATTTGAAAAAACTAGAACAAACGTTCGAATGCACACAGTGTGATAAATCATTTTCCTCTCAGGCATCATTGAAATTACACGAGCGTACGCATACTGGAGAACGGCCGTATGTATGCACGATCTGTAACAAGTCATACAAAACACCAGGCATGCGAACAGCACACATGGATACGCATATAGAAGGGAAAACGTTCAAATGTGATGTGTGTGGCAAATGTCTTCAAACACGTGCCTGTTATCGGAATCATGTGAAACGGCATTTAGAACAGCGCAATCACGAATGTTTCGTGTGTGGGAAGAAATTTTTCCAAAAATGTACTCTCCGTGTACATTTGAAAATGGTACATAGAGTATCACGTGATGTGCTGGATGCGTAA
Protein Sequence: MGEVCLDIDLHKVCRICLSQTDTNDILFNIFTDAIVDGMFVTLCEVIEDCVGIQVSNTAEAPDKICQTCKSIIFQFHVFKQKCHRAENLLRTMVEHRTPRRIAEGVNEIDSEEINYTEQQTTFYQRADEPSICQEPSPSVEFVEETIEEEVMGVIINNKEASSSEEWYNFIAQSPDTFRMSKEANVHSPNGVGMASASCEDNLHPSTISESPNFAKKSTFQSMMDHSLKENNRYVCDICGKVIISRSRLTKHMKLHNDSKIVLDHMRFFSCTFCEYVFLREDNFNEHNRDCAERPAKYESDHISKSLEKGNVGSGVCGICDARYDDMLHLKQHIITHLDKFPCPLEACGCEYASLARLIIHISTQHVEYLSPNCPHCKEEIDRVDIRQHVRLFCKAKQYQCTHCDRKFLSWKALSQHLKKLEQTFECTQCDKSFSSQASLKLHERTHTGERPYVCTICNKSYKTPGMRTAHMDTHIEGKTFKCDVCGKCLQTRACYRNHVKRHLEQRNHECFVCGKKFFQKCTLRVHLKMVHRVSRDVLDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -