Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: AXCM01002283:1-4900[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.97 57 4.2 1.1 2 23 12 33 11 33 0.83

2 20 1.3 77 3.7 0.3 1 23 39 59 39 59 0.83

3 20 7.3e-05 0.0043 17.1 0.2 1 20 71 90 71 91 0.97

4 20 0.002 0.12 12.6 0.8 2 23 100 121 99 121 0.97

5 20 7.4e-05 0.0043 17.1 0.4 2 23 127 148 126 148 0.93

6 20 0.54 31 5.0 1.3 3 23 158 178 156 178 0.94

7 20 0.00052 0.03 14.5 1.3 3 21 186 204 184 205 0.94

8 20 0.002 0.11 12.6 3.1 1 23 216 238 216 238 0.98

9 20 0.00058 0.034 14.3 2.5 1 23 244 267 244 267 0.98

10 20 0.00076 0.044 13.9 3.5 2 23 657 678 656 678 0.97

11 20 0.0076 0.44 10.8 0.6 1 23 716 738 716 738 0.96

12 20 0.39 23 5.4 0.6 8 23 774 790 761 790 0.76

13 20 1.5 84 3.6 0.1 2 23 797 818 796 818 0.95

14 20 4.8e-05 0.0028 17.7 0.6 1 20 857 876 857 877 0.96

15 20 0.0056 0.33 11.2 0.6 2 23 886 907 885 907 0.96

16 20 0.0013 0.078 13.2 0.8 2 23 913 934 912 934 0.92

17 20 0.63 37 4.8 3.3 2 23 943 964 942 964 0.95

18 20 4.1e-05 0.0024 17.9 1.3 3 21 972 990 970 991 0.94

19 20 5.1e-06 0.0003 20.8 0.9 1 23 1002 1024 1002 1024 0.99

20 20 0.00058 0.034 14.3 2.5 1 23 1030 1053 1030 1053 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.97	57	4.2	1.1	2	23	12	33	11	33	0.83
2	20	1.3	77	3.7	0.3	1	23	39	59	39	59	0.83
3	20	7.3e-05	0.0043	17.1	0.2	1	20	71	90	71	91	0.97
4	20	0.002	0.12	12.6	0.8	2	23	100	121	99	121	0.97
5	20	7.4e-05	0.0043	17.1	0.4	2	23	127	148	126	148	0.93
6	20	0.54	31	5.0	1.3	3	23	158	178	156	178	0.94
7	20	0.00052	0.03	14.5	1.3	3	21	186	204	184	205	0.94
8	20	0.002	0.11	12.6	3.1	1	23	216	238	216	238	0.98
9	20	0.00058	0.034	14.3	2.5	1	23	244	267	244	267	0.98
10	20	0.00076	0.044	13.9	3.5	2	23	657	678	656	678	0.97
11	20	0.0076	0.44	10.8	0.6	1	23	716	738	716	738	0.96
12	20	0.39	23	5.4	0.6	8	23	774	790	761	790	0.76
13	20	1.5	84	3.6	0.1	2	23	797	818	796	818	0.95
14	20	4.8e-05	0.0028	17.7	0.6	1	20	857	876	857	877	0.96
15	20	0.0056	0.33	11.2	0.6	2	23	886	907	885	907	0.96
16	20	0.0013	0.078	13.2	0.8	2	23	913	934	912	934	0.92
17	20	0.63	37	4.8	3.3	2	23	943	964	942	964	0.95
18	20	4.1e-05	0.0024	17.9	1.3	3	21	972	990	970	991	0.94
19	20	5.1e-06	0.0003	20.8	0.9	1	23	1002	1024	1002	1024	0.99
20	20	0.00058	0.034	14.3	2.5	1	23	1030	1053	1030	1053	0.98

Sequence Information

Coding Sequence: ATGGAGCAGGAGCACAATAAGGGAGCATACCTAAAATGTCCAATATGTAACAAGAGGAATCTGTACCGGCAGCACTTGATCACGCACATAGATTTGCATAACAATCCTGAGAAGTATCGGTGTGAAGTTTGTAAAGAAATCTATCAAAACCTTGACTCGCACATGATAAAAGCGCATACACCGACCACGGCGATACCAGCGGATAAAAAGTACAAGTGTGACCAATGTGGCCGAATGTTCAACTTTTTGGCGAACTTGAAAATGCATATCGATTGTATTCACGGTTCCAAAGATGTTCGCTGCAACGTATGCGACAAATACTTTAATTTAAAGGCGTTCCGAGCGCACAAGCGAACAGCGCACACCGACCAGCTGCTAATGTGCGAGCACTGTCCGAAGATGTTCAAAACACGTGGTGCGCTGGAAGTACACAAAGGTATTCACGACGATAGCTTAGTGCAGTTTACTGCGTGCAAGTTATGCAACAAGCAAATACGGCTAACGAACGTAAAGAAGCACATGACATCGCAGCACTCCCAGGATGGACCGGTAAATTGCGAACTGTGCGGAAAAATATTCCGTACGATGTTCCACATGAAGCGTCACCAGAAGAACACGTGCGAGGCAACGATCAATTCGCGAAAGCACAAGTGTGAAGTGTGCGGCAAAGGTTTCTGTCTGAAGTTGACCATGATCGAGCATATGACGACGCATACGCGCACGAACCAGTATCAGTGTGCGTTCTGCTTCAAATCGTTCGGCTACATCTCTAATTTGTACAAGCACCGGAAGAAGGCCCACCCGCAGGAATGGCAGGAGGTACAGGCCCGTCCTGAGGAGGGCATATCGTCGGTCATTGTTCTAAAACCTGCAGCAAATCCATACATCTGCATCGATTGTTGGAACACCGTGAATGAGTTTCATCTGTTCTACACTAAGCTAGAAACCATCCACAACGAAAGTTTGGAAAATGCGTCAGAAGCGATTTTAGACATCAACGAACTAAAGGATATAGAATATCTGGAGGAAGACACCGACGAGCTGTTACAGATTACAAGCGTTAAACGAGAAAGTGATAAAAATGTTAATTACCCAAAAAAGAGCGACATCAAGTGTGATCCGATCGAGCTGGATGGGTACCGGATTGTTGAAATTGAGGTTGCTGATGATGCTGAAAATGATGATCACCCGAATGACACGGACGACGAGGAAAGTGAATATGAACCACCGGGAACACCGGACCATCGTACCAAACCAGTCATATTGAATGGAAGAACGAAAACTAATGTTGCTAGCGAAAGCTCTACGATTGCTATCGATATTCTGGAACCAGAAGAACCAGTAGCTGTGAAGCGTGGCAGAGGTCGCCCTCCGAAGCGGAAATCTGAACAGCAACAAGCTTATACACCGACCGAAGTGCCTGCGAGGATAAAGAAGGAATTAAATGATTCCGGCGCGTCTGCCCATTCAACTGGTGTCGTAAAGCGTGGCCGGGGTCGACCTCCCAAGAGTATAAAACAGGAGCAAAATGCAACTTACAGTACACCACGAACCGTCAAGAAGGAGATAGCATCGGAAAGCACCGACGAGGTGACACCCGAACGGTACGCATCTGGTCGACCGGAAAGAAGATCAACACGTGTACGAAAGGTCAAACGCTATAGCGACATGGAACAAGTGACCGATGATGAGGACGAGGAAAATGACGACCCGGACGAAGAATATGTGCTTGGTGAGGATCCGGATTACGAAGCAAGATTGGAGCTACAGAAACAGCTTGACATGGATGACTATTCCTTCTACGAGTACCAGTGCAGCCTAGAGTCGGAACAGGTGGCACGCGATAATAAAATATTCCAGTACGTGGAAGAATTCGCTTGCTACCTATGCTCGGAGAAGGTCACGTTTAAGCGGTTCGCTGATGCGCATCTACACTATCGCGTGGAGCACAATCAGCCGCCTTTTTTGAAGTGTCCAAAGTGTGACAAAAAGTGCCACACGCCGGGTATGTTCGTCAGTCACATGGAAACACATGATGATCCGGAGAAGAACAAGTGCAACGTTTGCGGGAAGCTCAATGATTGTAACATATCGCTTAAAAAGCATATGCGCGTACATCAGAGCCAACTGGAGGAGAATCTACCGTATCCCTGCAGCCTTTGCAAGCGCAAGTTTGCGACGGAGGATCTGCGAGCCAAGCACGAAAAGTTGCACGTACCAAAGCCTTACGTACCGAAGGAAAAGGGCCCCGATCAGGAAGTGCTCGAATTTTACAAAACCATCGTTTGCGACATATGCGAAGAGGAAACGCACGATTCACCATCGTTCGACAATCTGAGCGACTTGCGGGCGCACATGGTGAAGGAGCACAACAAAAACATGTACATACGGTGTCCGGTGTGCTCGGCGAGACAATCCAACCGCCAGCAGGTCATCACGCACATTGACATGCACAACAATCCGGACAAATATCGGTGTGAAATTTGCAACGAAGTGCACCAGAATCTGCACCATCATATGCTGAAAGCGCATACGGCGAATACGGAACAAACGGCCGAAAGTGCAAAGCACAAATGTGATCAATGTGGTAGAACGTTTACCTTTTTGGCAAATTTGAAAATGCACATCGATTGCGTCCATGGTCTGAAGGATGTACGCTGTAACATCTGCGACAAGCTTTTCAACTATAGAGCCTACCGTGCCCACAAACGAACCGCTCACACTGACCTGATGCTGATGTGCGAACTGTGTCCACGAATGTTCAAGAATCGCAAATCGTTCGAGGCACACAAAGCGTTCCACGACAGTTCCCTGCTGCGCATGACACAGTGTACGCTCTGTGGCAAACAGATCCGTACGTGCAGCATGTCCAAGCACATGAAAACGATCCACTCAGAAGATGATCCGGTAAATTGCGATCTGTGCGGCAAGATGTTCCGCACACCGTTCCACATGAAGCGTCACCAGAAAAACACGTGCGAGGTAACGATGGATTCGCGCTCGTTCAAGTGCGAGGTATGTGGCAAGGGTTTCTCCACGAAGCTAACGATGACCGAACACATGACGACGCATACGCGCACGAACCAGTATCAGTGTGCGTTCTGCTTCAAATCGTTCGGCTACATCTCCAACTTGTACAAGCACCGGAAGAAGGCCCACCCGCAGGAATGGCAGGAGGTACAGGCGCACCCGGAAGAAAACATTCCGTCGGTTATTGTTGTGCAAAACTAA
Protein Sequence: MEQEHNKGAYLKCPICNKRNLYRQHLITHIDLHNNPEKYRCEVCKEIYQNLDSHMIKAHTPTTAIPADKKYKCDQCGRMFNFLANLKMHIDCIHGSKDVRCNVCDKYFNLKAFRAHKRTAHTDQLLMCEHCPKMFKTRGALEVHKGIHDDSLVQFTACKLCNKQIRLTNVKKHMTSQHSQDGPVNCELCGKIFRTMFHMKRHQKNTCEATINSRKHKCEVCGKGFCLKLTMIEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPQEWQEVQARPEEGISSVIVLKPAANPYICIDCWNTVNEFHLFYTKLETIHNESLENASEAILDINELKDIEYLEEDTDELLQITSVKRESDKNVNYPKKSDIKCDPIELDGYRIVEIEVADDAENDDHPNDTDDEESEYEPPGTPDHRTKPVILNGRTKTNVASESSTIAIDILEPEEPVAVKRGRGRPPKRKSEQQQAYTPTEVPARIKKELNDSGASAHSTGVVKRGRGRPPKSIKQEQNATYSTPRTVKKEIASESTDEVTPERYASGRPERRSTRVRKVKRYSDMEQVTDDEDEENDDPDEEYVLGEDPDYEARLELQKQLDMDDYSFYEYQCSLESEQVARDNKIFQYVEEFACYLCSEKVTFKRFADAHLHYRVEHNQPPFLKCPKCDKKCHTPGMFVSHMETHDDPEKNKCNVCGKLNDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFATEDLRAKHEKLHVPKPYVPKEKGPDQEVLEFYKTIVCDICEEETHDSPSFDNLSDLRAHMVKEHNKNMYIRCPVCSARQSNRQQVITHIDMHNNPDKYRCEICNEVHQNLHHHMLKAHTANTEQTAESAKHKCDQCGRTFTFLANLKMHIDCVHGLKDVRCNICDKLFNYRAYRAHKRTAHTDLMLMCELCPRMFKNRKSFEAHKAFHDSSLLRMTQCTLCGKQIRTCSMSKHMKTIHSEDDPVNCDLCGKMFRTPFHMKRHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMTEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKKAHPQEWQEVQAHPEENIPSVIVVQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -