Acul002587.1
Basic Information
- Insect
- Anopheles culicifacies
- Gene Symbol
- -
- Assembly
- GCA_000473375.1
- Location
- KI422544:3822-8439[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 9.4 5.5e+02 1.1 0.9 8 23 218 234 201 234 0.70 2 18 0.11 6.3 7.2 0.2 2 19 242 259 241 261 0.94 3 18 9.4e-05 0.0055 16.8 4.0 1 23 294 317 294 317 0.97 4 18 0.031 1.8 8.9 0.4 3 23 324 344 322 344 0.94 5 18 5.7e-05 0.0033 17.5 2.2 1 23 348 370 348 370 0.97 6 18 0.014 0.8 10.0 0.1 2 23 381 403 380 403 0.95 7 18 0.0025 0.14 12.3 2.2 2 20 410 428 409 430 0.94 8 18 1.6e-06 9.3e-05 22.4 1.0 1 23 439 461 439 461 0.98 9 18 0.0025 0.14 12.3 4.1 1 23 467 490 467 490 0.97 10 18 5 2.9e+02 1.9 0.4 9 23 693 708 675 708 0.76 11 18 0.0012 0.067 13.4 0.1 2 23 716 737 715 737 0.97 12 18 0.029 1.7 9.0 0.7 1 23 743 763 743 763 0.89 13 18 0.0017 0.1 12.8 1.1 1 23 768 791 768 791 0.97 14 18 0.0067 0.39 11.0 0.8 2 23 797 818 796 818 0.94 15 18 0.00093 0.054 13.7 5.4 1 23 822 844 822 844 0.97 16 18 0.36 21 5.5 0.2 2 23 855 877 854 877 0.94 17 18 4e-05 0.0023 18.0 0.6 3 20 885 902 884 904 0.94 18 18 0.0018 0.1 12.8 1.5 1 21 913 933 913 934 0.94
Sequence Information
- Coding Sequence
- ATGGCAACCAAATGCGAAGTATGCTTCTCGAGGACCGAAGGCAATGCGAAGGAAATTTTCACCGACGAAAATAAGCATATTGTAGGAATCGTAGAGAAACATCTGGGGTTTGAGGTACAACAAACAGCAGAAAACAGCTGGTTGTGTATCAAATGCTGGGATGCTTTGAACGAATTTCACAAGTTTTACTGTGAAGTTAAGATCGCCCGACAACGAGAAACGGAGACGCTAGATGAAAATGACGAGGATGATGTTGCCGGTAGCTTGGAACCGAAATACCATACCGAGTTTTTCGAGGTAAAGGTAGAACCGCTTGAACTGATGGGTACCATTGAGCAAGAAGATGCGAACTGTACGGATGAAAAAGCACTCCACTGCGCTTTCGTGAAATGTGAAGATTCAATCGAAATAGATCCTACTGCTCCTACGTCGGACGAAGAAGCCCTTCAGGGCAGTAAATCGGATTCATCTTCGGCTGATGGTGGCAAAAATCAGCTGAAGAAAAGATCGAAAAAACCCCACACCGACGAAGAGGCAAAGCAGAACAAATCAATCGCTCAGAAGGAGGAGGATGAAAGTTTGATAAGTTTCTACAAAAGGATAGTCTGTGAGGAATGTGATCAACAGCGAATGATGGTTGGTGAGCCTCAGATCGATTTCGGTACTTGGCGCGCTTTGCTACGGCATACGAAGGAGGTCCATAAACACGACAAAGTGTACGTAAAATGTCCGTTGTGTGAGCTGAAGTTGCGAACGAAGCAAACTCTCATACAGCACAAGGATTGCCATGAAAATCCGGAAAAGTATCGCTGTGCTCTGTGCAATGAAATACACCAGAACATGAAGGAACATTTGCAGAACAAACACCAAGAAAGGCAGTTCTGTTGCGATGTGTGTGGGAAAAAGTTTCCATTCAAGAAGCGACTTACGGTACACATGAAGAAGATGCACGTGGAGAAGGACATCATTTGCGACCAGTGTCAAAAACCCTTTACAAAATATACGATCGAGGATCACAAACGATCCGTTCATTCGGCGCGATTTGTGTGCGAACACTGTCCGAAGACGTTCAACAGCCGGTTCCGTTTGCTTCAGCATATGGAGGAGCACGATGAAAGCCTTCGGAACTCCACCTCCGTACCGTGCACAATATGTGGACAGGTGATGCGTGACAAGTACATTCTTACCAGGCACATCAAACTAATGCACACCGTACAGCCGTCGGTGAGCTGTACTACATGCGGGAAAACGTTCAAATGCAAACGCAATCTTTCAGTGCACATGACAAACGTGTGTATGGAACCAACGCGACTTTTTCCCTGTACAATCTGTGGCAAAGAGTTCCGGCGAAGGAATAAACTGAAAGAACACGTGTCTACGCACACCGGTAAGCCGGTGTACAAATGTTCGTTCTGTCCAGAGACATTTCGTCAAGATACGCACCTGTACTACCATCGGAAGAATGCACACTACGAGCAGTGGCTGGAGATGCAGCAACAGCGCAAAGAAGGTGTCATTGGCACAGAAGAATGTAAATGGATATGCCAGAGCTGTTGGTCTAAACTGGAGGAGTTTCACCAATTCTATGTCACTATCCAAGAGACGCATAAACAACAAGCTATCGTCGACGAAAGTGAAAAGGTCAACGCCAAAGCGTCTTCGGATTCACCGACGATATGCAACGGTCCGGCATACAGTACGGAGTTCTTGGAGATAAAAGAAGAACCTTTCGATATCGAGGACGAATACAATGACGATGCATTTAGTTTGGAAGGGAGCAGTCCACAATGTGACAAGATATTATCCTGCGATGACATCAAGAGTGAGGAATCGGAAGAGAGCGAAAGCGATTCATCACAACCACCGGATAGACGAAAGAGAAGGGAAAAATCCACCCGATCGAGTGAACGACCAAGAAGCTCGAAGCAGTCGGCCGGTGAACGGCTTGCAAAGCGAAAGGCTGGCGGGCGCTTTCCCGCCGATCCGGAGGAGGATAAGAATATATTGCAATTCTACAAGCGCATTGTGTGTGAGGTGTGCGATAACAAGCGTATGATGGTCGGGGAACCACTGATAGAGTATGCGACCTGGGGCGAATTGTTGCGGCACACGAAGGAACAGCACGGCCATTATAAAATCTTCGTTCAATGTCCCGTGTGTGAGATGAAGCTGCGCACGAAGGTGACACTAGTGCAGCACATGGATATGCATCAGAATCCGGACAAGTACCGGTGTGAAGTGTGTGGCGAGGTGTTCCAGAACATGAAGGAACACATGCAGAACAAGCACGAAGAGCGACAGTTTAGCTGCGATTTGTGTGGCAGCAAGTTCCCCTTTAAAAAGCGGCTCGTAGTACACATGAAAAAGATGCACGCCGAGAAGAACGTCACGTGTGATCAATGCCAGAAATCCTTCACGAGATACACAATCGAAGACCATCGACGATCGGTGCACATGGCTCGGTTTGTGTGTGAACACTGCCCGAAGACGTTCAAGATTCGGTTCCGGCTGCATAAGCACATGCAGGAACACGATAAAAGCTTGCGCGTTTCCACGTCCGTGCCTTGTCCGACCTGTGGACAGGTGATGGGCGATAAGTACATTCTCCGTCAGCATATCAAGCACATGCACAACGAGCAGCAGGCCGTCGACTGTGAGACATGTGGCAAGACATTCAAGAACTATCGCAACCTGAAGATACATCTGACGAACGTGTGCATGAAACCGATCCAGCTGCATTCGTGTGCGATCTGTGCGAAGCAGTTCCGACACAAGAACAAGCTAAAAGATCACATGGCGTCCTGCATGCCGAATTGA
- Protein Sequence
- MATKCEVCFSRTEGNAKEIFTDENKHIVGIVEKHLGFEVQQTAENSWLCIKCWDALNEFHKFYCEVKIARQRETETLDENDEDDVAGSLEPKYHTEFFEVKVEPLELMGTIEQEDANCTDEKALHCAFVKCEDSIEIDPTAPTSDEEALQGSKSDSSSADGGKNQLKKRSKKPHTDEEAKQNKSIAQKEEDESLISFYKRIVCEECDQQRMMVGEPQIDFGTWRALLRHTKEVHKHDKVYVKCPLCELKLRTKQTLIQHKDCHENPEKYRCALCNEIHQNMKEHLQNKHQERQFCCDVCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHTVQPSVSCTTCGKTFKCKRNLSVHMTNVCMEPTRLFPCTICGKEFRRRNKLKEHVSTHTGKPVYKCSFCPETFRQDTHLYYHRKNAHYEQWLEMQQQRKEGVIGTEECKWICQSCWSKLEEFHQFYVTIQETHKQQAIVDESEKVNAKASSDSPTICNGPAYSTEFLEIKEEPFDIEDEYNDDAFSLEGSSPQCDKILSCDDIKSEESEESESDSSQPPDRRKRREKSTRSSERPRSSKQSAGERLAKRKAGGRFPADPEEDKNILQFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKEQHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPDKYRCEVCGEVFQNMKEHMQNKHEERQFSCDLCGSKFPFKKRLVVHMKKMHAEKNVTCDQCQKSFTRYTIEDHRRSVHMARFVCEHCPKTFKIRFRLHKHMQEHDKSLRVSTSVPCPTCGQVMGDKYILRQHIKHMHNEQQAVDCETCGKTFKNYRNLKIHLTNVCMKPIQLHSCAICAKQFRHKNKLKDHMASCMPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -