Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI422464:58-8692[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.1 1.8e+02 2.6 0.0 2 23 4 25 3 25 0.95

2 14 0.0014 0.083 13.1 1.1 1 23 1572 1595 1572 1595 0.97

3 14 0.0095 0.55 10.5 1.4 1 23 1734 1756 1734 1756 0.97

4 14 0.001 0.059 13.5 2.3 2 23 1759 1780 1758 1780 0.95

5 14 0.0007 0.041 14.1 1.8 1 23 1786 1808 1786 1808 0.98

6 14 3e-05 0.0018 18.3 3.4 2 23 1815 1837 1814 1837 0.96

7 14 0.0046 0.26 11.5 1.8 1 23 1847 1869 1847 1869 0.98

8 14 0.00015 0.0087 16.2 2.8 2 23 1875 1897 1874 1897 0.96

9 14 0.0086 0.5 10.6 0.6 3 23 1911 1930 1910 1930 0.97

10 14 5.8e-05 0.0034 17.4 0.9 1 20 1937 1956 1937 1959 0.92

11 14 0.00096 0.056 13.6 0.2 1 23 1967 1989 1967 1989 0.97

12 14 9.3e-05 0.0054 16.8 3.1 1 23 1995 2017 1995 2017 0.98

13 14 0.0005 0.029 14.5 5.8 1 23 2023 2045 2023 2045 0.98

14 14 0.0032 0.19 12.0 3.5 1 23 2051 2073 2051 2074 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.1	1.8e+02	2.6	0.0	2	23	4	25	3	25	0.95
2	14	0.0014	0.083	13.1	1.1	1	23	1572	1595	1572	1595	0.97
3	14	0.0095	0.55	10.5	1.4	1	23	1734	1756	1734	1756	0.97
4	14	0.001	0.059	13.5	2.3	2	23	1759	1780	1758	1780	0.95
5	14	0.0007	0.041	14.1	1.8	1	23	1786	1808	1786	1808	0.98
6	14	3e-05	0.0018	18.3	3.4	2	23	1815	1837	1814	1837	0.96
7	14	0.0046	0.26	11.5	1.8	1	23	1847	1869	1847	1869	0.98
8	14	0.00015	0.0087	16.2	2.8	2	23	1875	1897	1874	1897	0.96
9	14	0.0086	0.5	10.6	0.6	3	23	1911	1930	1910	1930	0.97
10	14	5.8e-05	0.0034	17.4	0.9	1	20	1937	1956	1937	1959	0.92
11	14	0.00096	0.056	13.6	0.2	1	23	1967	1989	1967	1989	0.97
12	14	9.3e-05	0.0054	16.8	3.1	1	23	1995	2017	1995	2017	0.98
13	14	0.0005	0.029	14.5	5.8	1	23	2023	2045	2023	2045	0.98
14	14	0.0032	0.19	12.0	3.5	1	23	2051	2073	2051	2074	0.95

Sequence Information

Coding Sequence: ATGGCTATCGAATGTCCCGTCTGTACGCTGTACCTGCGGTCTGGCATGACCCTGGCCGAGCATTTAGACACCCACCCGAAGGAGAATGTGATAAAGGCGTTGGTGAACAGAGTAGTTAAGCAAGATGCTGTGGGCTTCTTTCCTGGCTCGCTGGAAGAGCTGGGCTCAGACGAAATCCTTCCGGTGGAGGGCAGCACGCCTAGTATCGATAACGGCGCCGTCAGCAACACTCTGACCATCAGAACAAATGAGCGTACAACCGCACTAGGCATTTACGAGGCGCAACCAATGTACATGGACAACACTATACTAGCGTCATCCAGCAACACGGTACAAGCTTCAGTTAGCCAACCGTCCCAGTTTGCGGTGGTAAAAGCGATCGATGCACATGGTATTCCCAGCTTTCAGTTGAACAATGTGACGCTTATAAAGCGGGAAATAGTACAGCCGGTCGTGACGGTGGCTGGTGTGTCGTCGATATCAACGGTCGCTGCCGCAGCACCACCTGCCACCATTGGACCGGTGCAAAACGAATTGTCCGGAATTGGTTCCATGGGTGAAGATTACCTCGAACCGAGTGGGAATGGAACCGGTGAAGCAGGCTGCTCCCGTGTGGTAGGCCCGGCCGTTGCCTCTACCACCGTGTTTCCGCGTTACACCAATGAACTATATTCTGGACCACCGCCACCGTACAGTCGGGCCATATCCTCTACGGTTGCTACGAACACACAGATAACACCAATGCAACAGCAACAGCAAACCGTACAACTAAACCTACCGAAAAGCACAATCAGTGGTAGTGTGAGCGTTATCGGCCAGCAGATACAGCTACTTCCCAAGATTCACACCGAAACAACTAATTCCGCGTTCAAGCAGTATCCAACAGTGCAACCCGAACGCAGTGGGGATGAGTCGGCAAACCAATCGTCAGCTGCGTCAGCTCCAAAATCTGGTTACAGCGGAACAGCAACAACCATCGCTACAAGAATGGTTACGACGACGGCTATCACCACGACATGCAGCACCAGCTCGACGGCTACCGCAATCGAACAACCATCAACCGTCAGCACACCAGTAACAACGGCTTCAAAGAGCGCACAAAACGTGTCTAACTCATCGAAGGCGAACGTTGTAAAAGTAATAAGCAACGTCAAGGTGCAGAGTAAGCTGAAGGATATTCAGGAAATTATACTCCAGCTAAACGCCGGCCAGATGTCGATTGTCGGTGACAAGACGACGCTGATACCACCCACAACCGAACGCCGTGCATCAGCGTTTGCCTCGAGCGGTTCCGGTCGCTCTTTGCTAGCGATAGCACCTGCCAAAGTTGAATGCTCCAGCGAGGAACAGCTTCAGGAGCAGCAGCAGCAGGTTCAGTTGCCTGTTGTCAATAACAGAATGGAACAGGCGGAGCAGAACGGTATGGAACAGATGGCAGGTGATTACGATCACGAGGAGGAGTACAGCGATGCTTGGCAGGATGACGATAACTACGCAGACGATGAAATTCGTGAGCAATGGGAAGAGGCACCGGGTGCAAAGCGTTTTGCTAGCGGTAACGAACAATGTGAACTACATCCCGGTCAGCCTGTTGCACAAGATAAGACAGCATTAGCTACGATTTCCACCGGCATTGAGCCCAGCACCAACAGTACGAGTAGCGGTAATGCGATGGTCACTAGCGTTATCCGGAAAACACCCCAACCACTGCCATGTCTACCGTCACCCGTACAGCAGGATTCGAAGACACAAATAAAGCGGCTAGTATTTAGGGTGGCAGGTAATGCAACACCCACCACCGTCACAATATCTCCGGCCGGGCCGTCAACCTCGCCGAAAATTGTTCGTGCCTGGCAGGGTATCAAACTGGAATGCTCAACAGAAGATACGGGCGTCGCCAATGACGCAAATTGCGCTCCTGCCGATGAAGAGCCAGCAAAGCCGATGTCTTGTGCATCGTCTGCCTTGGCCGGTAGCGATTATGCGGCTAGGCAGAAGCAACGCTTTAGGCCACCaaaaaaaTTAGCAATCAAGCCAAAGCGTACCCATGCAGAAGGATGCAACTTTCCAAATCAGCATCCGGACGATTGTGTGCAAGGAAACGAGCCGATGACGAGTACAAACTCGCCCTGGACAAGCACACCATCGACTACGATCCCGCTGGCCACCGCACTTACTACATTGGCGGAAGTTGTGTGCACGAGCGCTGCACAACAACAGCAACAACCGAGCACGGAAACTTTTTCTTCCACGTCGTTCAACGGCATTACGGCCGTTATACAAAAGACTGACACTAACAGCGGGATTGCAGCCATTAGCCCTACGGTCCCGAGCCAAACTTACCAGTGTGCGGATCGCGAAACGATGGAGTATTCTCACCCTTCTACCACCCCACCGAAGGGTTACGTAAGCAGCCAGCAACTATTGATGGCTCCCATCAAGCAAGAGTATTCTCGTCCGGTAGACTCATCAATTCCCGATGTGCCACTGAACTCAACAAACAAAGCGAACCAAATGCTGCATGGCGGTGTCCGTGCGCCGTACACATTCGGCACACCCGAAACCGGTACTGCTACAAACGCTGGCCACAAACCGTTGCACCCTACCGACGAGATTGACGTCGGTGCGTACAATATTTCCTACGTCAGCGAAACGGGTGAAACGATCTACCATCCGTTGCCAAAGAAAGTCAAAAGAACGCCCAGAAGCGAGGACGACTGTTCAACCAGCCGGTCGGGTGGTGAAAATATGAACGTAGACCACGCCAACAGCCGTGCGATGGACAACAGGGATGGAAGTATGGAACTGATAGTGGAGGATGTGAAGGTATGTGGCGCAATACAGGGAGAGGATTTGCATGATCATTCAAACGCGTTGAATGAGAATGAGGAGATGATCCAGACAGAAGAGGATGAGAAGGAAACAACTGATGAAATGGATCAGGATGTAAGTGTAGTGCACGAGGACAGCGAGGAAGATGAGAATGATGATGATGTGTTCGAAGTGGAAGCTGTAAAGCACGAACAAAATCCATCCCCGATATCTTTAGCGTCCGAGCAGCCTTCACATCAACGCTTGCTAATGGTGTTGACTAGGGTGAACAACACTGTACCGACCGATACGCCTGAGCAGGATGCACATCCAACGTTCCTAAAGGATGCAGTGGAGACAGTCTTCGAGAGAGATTCGAAGGATAGTAGCTTGGTGCAGCAGGTCATCGAGAACAATACCATCCCGCCCGAAGAAGGTTTAGCACAGCCGTACTGCAAATCGGAAGGATCAATGAAATTGCCTGCAAATCTAGTGATGAAACGTTTGCATACCGAAATGATTTTTACCGCTGAGGAGAAGGATCTGCTTGAGGCTGGTCCTTCCTCTCGCGCTATCGTTCATGTTGGTGTGCCGCGGCCGAATGTTCGTGTTACGAATGCGGGACCATTCCAAATGTCTAGCCGCGCGATCCCTCGCAAGGCGGAAAAGGATGAACGAAAAAAGTCGGACACAGCGAAAAGAAGGTGTGGAAAAGATTTCCTCGAGGCAGGACCTCCAACCACGTCGTCCTCCACGTCGCTTGGGTTTGCGGCGGTCGGTCCCATATATGAGCAGAGGGAGGAGGGAAGTTGCTTTGATCATCATAGTTTCAACAGTCAATCCAACACTGCCAGCACCACCACCATGGTCGATGAACAGGTGCAACTATTGCCGGAATCGATCGTTGAACTGAAGCAAGCTAAAACAGAACCGTATATGGAAGATGAACAGGAGGAGGACACATCAACTTCGTCATTTCTGGATCTGAGCACGATACCGAAAAACAGCCTTGACGGTATGACAACCGATACAGCGAGCATCACAAGCCATAGCAGCAGTCACAGTGCCGGCCTAGGGAAGGACAATGGCGAGGGGAGCGGTGGAACACGATCACTGCTACCGTCCGGCTCATCGATCACATCCACCAGCATGGAACGGGCACCATCAACCGAAAGTCTTAACATACGCACTGACGAAAAGATGCCGGCAAAGGGTGAAATTTCTGAACAGGAAAGCAACGGCGATATGGATGTCACTTCCTGGAACCATCGGATGTACGCGGTCGGTGAGAACATGCCTATATATCCGAGCTCATACGATTTGTCGACGGCACAGGAGTGCTGGAATTTGAGCAGCCGGAATCAGGGCATGTTTGCAGTAACGGATCATTTCTACCATCAACAGCAGCACAGCGGTGGTAACAATACGCACGGAAACACTGTCAGCAACCAATACATGCATTCACATGTTGCATTCCAATTTTCGTCCAATTCACATCAACAGTTGCAGCAGCATGGGCCAGATATGCAGTTCGGTAGCAGCATTATAACGAGCAAAGTTGAGCCACACCAGGACGACGACAATGATAGTGATGATGTGGACGAGCAGGCGGAGGGACGCCGGTTGAAGAACGCCATTCCCAAATTGCCGTTCGCTGACATGATGGTGGCACGGATGCATGAACCACCCGGTGCTTATGACGAGGTGGTCACCCAACACCATCACCAGCAGCAGCCACTGCAGCAGCAACAATCGTGTGAAATGAAGTATGATGATCCCGTCGGTACCACGTCGTACTTCGGTGTTGCGGTAGCTACGTGTTCTACCTTGCCGCTAATGTCCTCGGAGCAACCGGTATTGCCCAGCCGTCCGAAACCATCCGGCAGTGGGGTTACACGCACCTTCCGCTGCACACTCTGCCCGAAGGTGTTCGATACGATCAAGCAACGCCGAGTGCATCAGCAACGAGAACATGCGAACGAACTGCTGTCGTTGTCATCCCACACACAGAACGGGCACGGTGTTGATCGAAGCGGTGAGGGAcagcagcaacagcagcagcagcagcagGTGTACAAGAAGCAACCGATACCGGTCGTAATGAACTACGATTGGATGAAGCAGGAAATTGAACGTAAAAGCGAAGCTTCGCTGAGGAGTAGCCGTATGCTGATGCAGGGCTGCAGTAGCAGTACTAGCAATGTTGCCGTGCCAGGTACGAGTGGGGAAGAGATGCAACAAGAGCAGAAGCTCTTAGTGGCACAGGTACAGATGGCCGAAGGGAGTGCGATAGTTGGTAGTAGTAGTGGTGGTGGTATCGCACCATCGATGATGCGAGATGAAGGTATGTTGTCGACCGCATGTACGGTAGCAGCACGCAATCGTTCGTATGTGTGCAGCACCTGCAACCAAAAGTTCGATCGGTTCAACCTGTTCAATGAACATTTGCTCGAGCATCCAGTTGAGTGTTTTGCCTGTGGACGTCACTTTAAGCAATGGCGTAACTTTTCACTCCATATTAAGCGCCATCTCGGCATTAAGGAACATCAGTGCCGGAGCTGTGGTAAACAGTTCGTGATCAAGCAGAAGCTGATAGAGCATATGCGGGTGCATACAGGCCATGCACCGATCAAGTGCAAGCTGTGCAATCGCTCGTTCAAGCGATTCTCCAATCTGGCCCAGCACCGGAAGCGATACCATCTGAACCGAACCGTAACAAAAGAGGATTACGTGTGTCAGCTGTGTGGGGAGGTGTTTCACACCCATGCCAAAATGGAATGGCACAAGGAAACGCATGAGAAAAAGCCCAAATCTTGCCCATACTGTCGGGAAAAGTTCATACATAGGAACAGCTTAACGCGTCACATACGTCTGTCGCACACGGATAAGTATGCGAAGCTGGAGAACAAAACCGAACCGTGCAGCATCTGCCAGCAGCCGTACACGAAGACTAGCATGCGACGTCACATGGAAACGCACACCAAGGAACGGATGGCGTATGCGTGCGGTATCTGCAACAAGCGGTTTACGACGAACTGGAACCTGAAGCAGCACAAATGGACGCATGCGAACCCGACAATGAAACCGTTCCAGTGCACGTACTGTCCGAGTGCGTTCGTGCGCGAATCGGACTTTGTGACGCACGTGAATGCGCACCGGTCCATTCGGCCATACACGTGCAACCATTGCGGAAGTCAATTCATACGGAAGTACAACTGGATAAGACATACGCGCGAGCACGAAATTGACAAGGGCCACCGGTGCGATGTGTGCGGCCGTCAGTTCCACCGGAAGTATTACCTGACGGAGCACAAGCGCATCCATACGGGCGAGCGACCGTTTGCGTGTAATATCTGTGGTAAAACATCCGCCACCAAGACAAACCATAACAAGCACGTACGAATCCATCATGCGCGGGATCCTCTTACGGCAGAAGGTTAA
Protein Sequence: MAIECPVCTLYLRSGMTLAEHLDTHPKENVIKALVNRVVKQDAVGFFPGSLEELGSDEILPVEGSTPSIDNGAVSNTLTIRTNERTTALGIYEAQPMYMDNTILASSSNTVQASVSQPSQFAVVKAIDAHGIPSFQLNNVTLIKREIVQPVVTVAGVSSISTVAAAAPPATIGPVQNELSGIGSMGEDYLEPSGNGTGEAGCSRVVGPAVASTTVFPRYTNELYSGPPPPYSRAISSTVATNTQITPMQQQQQTVQLNLPKSTISGSVSVIGQQIQLLPKIHTETTNSAFKQYPTVQPERSGDESANQSSAASAPKSGYSGTATTIATRMVTTTAITTTCSTSSTATAIEQPSTVSTPVTTASKSAQNVSNSSKANVVKVISNVKVQSKLKDIQEIILQLNAGQMSIVGDKTTLIPPTTERRASAFASSGSGRSLLAIAPAKVECSSEEQLQEQQQQVQLPVVNNRMEQAEQNGMEQMAGDYDHEEEYSDAWQDDDNYADDEIREQWEEAPGAKRFASGNEQCELHPGQPVAQDKTALATISTGIEPSTNSTSSGNAMVTSVIRKTPQPLPCLPSPVQQDSKTQIKRLVFRVAGNATPTTVTISPAGPSTSPKIVRAWQGIKLECSTEDTGVANDANCAPADEEPAKPMSCASSALAGSDYAARQKQRFRPPKKLAIKPKRTHAEGCNFPNQHPDDCVQGNEPMTSTNSPWTSTPSTTIPLATALTTLAEVVCTSAAQQQQQPSTETFSSTSFNGITAVIQKTDTNSGIAAISPTVPSQTYQCADRETMEYSHPSTTPPKGYVSSQQLLMAPIKQEYSRPVDSSIPDVPLNSTNKANQMLHGGVRAPYTFGTPETGTATNAGHKPLHPTDEIDVGAYNISYVSETGETIYHPLPKKVKRTPRSEDDCSTSRSGGENMNVDHANSRAMDNRDGSMELIVEDVKVCGAIQGEDLHDHSNALNENEEMIQTEEDEKETTDEMDQDVSVVHEDSEEDENDDDVFEVEAVKHEQNPSPISLASEQPSHQRLLMVLTRVNNTVPTDTPEQDAHPTFLKDAVETVFERDSKDSSLVQQVIENNTIPPEEGLAQPYCKSEGSMKLPANLVMKRLHTEMIFTAEEKDLLEAGPSSRAIVHVGVPRPNVRVTNAGPFQMSSRAIPRKAEKDERKKSDTAKRRCGKDFLEAGPPTTSSSTSLGFAAVGPIYEQREEGSCFDHHSFNSQSNTASTTTMVDEQVQLLPESIVELKQAKTEPYMEDEQEEDTSTSSFLDLSTIPKNSLDGMTTDTASITSHSSSHSAGLGKDNGEGSGGTRSLLPSGSSITSTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDVTSWNHRMYAVGENMPIYPSSYDLSTAQECWNLSSRNQGMFAVTDHFYHQQQHSGGNNTHGNTVSNQYMHSHVAFQFSSNSHQQLQQHGPDMQFGSSIITSKVEPHQDDDNDSDDVDEQAEGRRLKNAIPKLPFADMMVARMHEPPGAYDEVVTQHHHQQQPLQQQQSCEMKYDDPVGTTSYFGVAVATCSTLPLMSSEQPVLPSRPKPSGSGVTRTFRCTLCPKVFDTIKQRRVHQQREHANELLSLSSHTQNGHGVDRSGEGQQQQQQQQQVYKKQPIPVVMNYDWMKQEIERKSEASLRSSRMLMQGCSSSTSNVAVPGTSGEEMQQEQKLLVAQVQMAEGSAIVGSSSGGGIAPSMMRDEGMLSTACTVAARNRSYVCSTCNQKFDRFNLFNEHLLEHPVECFACGRHFKQWRNFSLHIKRHLGIKEHQCRSCGKQFVIKQKLIEHMRVHTGHAPIKCKLCNRSFKRFSNLAQHRKRYHLNRTVTKEDYVCQLCGEVFHTHAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHMETHTKERMAYACGICNKRFTTNWNLKQHKWTHANPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -