Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI424184:12362-14783[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.7e-05 0.0021 18.1 3.3 2 23 358 379 357 379 0.97

2 9 0.0033 0.19 11.9 0.3 1 23 385 409 385 409 0.97

3 9 4.6e-05 0.0027 17.8 2.2 1 23 415 437 415 437 0.98

4 9 0.00019 0.011 15.8 1.9 1 23 443 466 443 466 0.97

5 9 0.00015 0.009 16.1 0.7 1 23 472 495 472 496 0.94

6 9 2.2e-07 1.3e-05 25.1 2.5 1 23 506 528 506 528 0.98

7 9 1.8e-05 0.001 19.1 0.2 1 23 534 556 534 556 0.98

8 9 0.00084 0.049 13.8 1.1 2 23 563 584 562 584 0.97

9 9 2.3e-06 0.00014 21.8 0.2 1 23 590 612 590 612 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.7e-05	0.0021	18.1	3.3	2	23	358	379	357	379	0.97
2	9	0.0033	0.19	11.9	0.3	1	23	385	409	385	409	0.97
3	9	4.6e-05	0.0027	17.8	2.2	1	23	415	437	415	437	0.98
4	9	0.00019	0.011	15.8	1.9	1	23	443	466	443	466	0.97
5	9	0.00015	0.009	16.1	0.7	1	23	472	495	472	496	0.94
6	9	2.2e-07	1.3e-05	25.1	2.5	1	23	506	528	506	528	0.98
7	9	1.8e-05	0.001	19.1	0.2	1	23	534	556	534	556	0.98
8	9	0.00084	0.049	13.8	1.1	2	23	563	584	562	584	0.97
9	9	2.3e-06	0.00014	21.8	0.2	1	23	590	612	590	612	0.98

Sequence Information

Coding Sequence: ATGAGTAACGTGTTGTGTAGATTGTGCTTAATCAAGTGTGAAGAATTGTTCGGAATGTACATCACCTCGCCTAGCGGTGTACTGCGTAGTCTGCCGAAAATCATACGAGAATGCATCTCCATCGAGGTAAACGATCTCGAGCCGAACTTTTTCTCAAAGTTCGTATGCAACGAGTGTGTCTACAAGCTGGAATTGTTCTATGCCTTTCGGCAACAGAGTCTCAAGAGCCAGGATTACTACAATGGCCTAATACAATACTACCAGCAATCAGTGCCTTGCTCCAGTAAGATATCACTGGATCATACAGCTAACGCCGATCAGGTGCCTGGATCGGTAGATAGTGTATTCGAACCAGAGCAGTCAGTTCATTCAAACAACGAGCTGGCGGACATAAACTTTTCCGGTAATGAGTTTATGATGGATGAGTCGGaaaaaaaTCAGCTAAGCAAGGATTATGATGATATAATTCGCAACTTGCAGAAAGAAGACCTCGATTTTACAACAAATGATGGTGAACTAGCGATGAAGCATGAATTGGGAATCTCAATATCGACGAACGATACCAGAATGAACAAGGACGTTGCGCTACAGCAAGAATGTCCGAGCTACCTTCCACACGTGGATGATGTCGTGGTAAATATTGCGCAACCTACGGAGCCTGGTGACAACAATTGCTTCGACCCATACAATACGATGAGCGTAGCGTGTGATAAGGATATGATCAACAGTAGTACGCTTTCCGTCGAACAGGACGATGATCTTAACTATGATGATTTTGTGGGCATCCAAACGTCACCGTTAGAGGATAATCGAGATATGTCACTATCAGAAGTGCACGTGCAAGACATAATAGCGGACGTGTACAATGTACATCCACCAGACAAGGTACAGGCAACGGATACCGTTTCATCCTCACAACCAATGGCTGACGTTCAGTGTAGTGAAATATCGGCTCTGCAGCAGAATGATGGTTCGTACTTTTCCTTGGTTGACTTCAGCGAAACCGAACTAGCGGGCGCCAGCAGCAGTACAACTTGTGCGAACGGAACAACCGAGTTAGCAAATGATAAAACGTGCGAGATTTGCTTTAAAACGTTCCGCACCAGGCAAAAGCTTACCATCCACCGTAACACGCACCTCCGATTGGCACCGTTCAAATGTACGTTTGAAGGATGCACCAAAGCGTTCAAGTCACGCATCGGGCTCGACGAACATGTGGCCCGCCACACGAACAGCTTCGAGTTTAGCTGTGACATTTGCTCGAAGGGATTCCAGCACCGTAGCTATCTGTCCGCCCATCGACGAGCGCACAATACCGAGCGAAACTTCCAGTGTTCGCTGTGCGAACAAACGTTCAAGTCGAAGCAAGCGTTACTAGATCACAAAAACCGTCGCCATCTCGGAGTGAAACCGTTCGCATGCGAACTGTGTGACAAGCAGTACACGAAGAATGCACTGTTGCGAGCGCACATTGAACAACAGCATCATGGCAAGCGGGAAGATGTGAGTACGCGCTATCCATGCCAGGAGTGTGGGAAACATTTCACTTCCAAAAGCTACCTGAACGTACACAAGCGAATACACCGGAATGAGCGACCGTTCGTGTGTGAGGTCTGTAATAAGGGGTACATCACGCGGAAAGATCTTGCCGTTCACATGACAAGCcacacgggcgagaaaccgcttacctgtgacatttgcggcaaggcgtatgctcgtcgtaacgccttagactgtcatcgccggacgcatactaacgaacgtccatacgtctgtgatatctgtggtcaatcgtttacTCAGCCCACACCGTTAAGGGTACATCGGAAACTACACGAAACGGTGGATGGTCATAACAAAAGCTTGAAGCAATCACCGATGGGAGTCATTGATGGTACGTCAGCACAGAACCGGCAATAG
Protein Sequence: MSNVLCRLCLIKCEELFGMYITSPSGVLRSLPKIIRECISIEVNDLEPNFFSKFVCNECVYKLELFYAFRQQSLKSQDYYNGLIQYYQQSVPCSSKISLDHTANADQVPGSVDSVFEPEQSVHSNNELADINFSGNEFMMDESEKNQLSKDYDDIIRNLQKEDLDFTTNDGELAMKHELGISISTNDTRMNKDVALQQECPSYLPHVDDVVVNIAQPTEPGDNNCFDPYNTMSVACDKDMINSSTLSVEQDDDLNYDDFVGIQTSPLEDNRDMSLSEVHVQDIIADVYNVHPPDKVQATDTVSSSQPMADVQCSEISALQQNDGSYFSLVDFSETELAGASSSTTCANGTTELANDKTCEICFKTFRTRQKLTIHRNTHLRLAPFKCTFEGCTKAFKSRIGLDEHVARHTNSFEFSCDICSKGFQHRSYLSAHRRAHNTERNFQCSLCEQTFKSKQALLDHKNRRHLGVKPFACELCDKQYTKNALLRAHIEQQHHGKREDVSTRYPCQECGKHFTSKSYLNVHKRIHRNERPFVCEVCNKGYITRKDLAVHMTSHTGEKPLTCDICGKAYARRNALDCHRRTHTNERPYVCDICGQSFTQPTPLRVHRKLHETVDGHNKSLKQSPMGVIDGTSAQNRQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101846;
90% Identity: iTF_00105302;
80% Identity: -