Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI422699:32015-35843[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00075 0.043 14.0 3.0 1 23 163 185 163 185 0.98

2 11 3.7e-05 0.0022 18.1 1.0 1 23 191 213 191 213 0.98

3 11 4.4e-05 0.0025 17.8 7.4 1 23 219 242 219 242 0.97

4 11 3.9e-05 0.0022 18.0 1.8 1 23 248 270 248 270 0.98

5 11 1.1e-05 0.00067 19.7 2.2 1 23 276 298 276 298 0.99

6 11 0.0001 0.0058 16.7 0.7 1 23 304 326 304 326 0.98

7 11 0.00059 0.034 14.3 1.8 1 23 334 357 334 357 0.96

8 11 0.0004 0.023 14.8 1.2 2 23 364 385 363 385 0.97

9 11 0.002 0.12 12.6 0.7 1 23 391 413 391 413 0.97

10 11 2.2e-05 0.0013 18.8 2.6 1 23 419 442 419 442 0.97

11 11 5.9e-06 0.00034 20.6 3.3 1 23 456 478 456 478 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00075	0.043	14.0	3.0	1	23	163	185	163	185	0.98
2	11	3.7e-05	0.0022	18.1	1.0	1	23	191	213	191	213	0.98
3	11	4.4e-05	0.0025	17.8	7.4	1	23	219	242	219	242	0.97
4	11	3.9e-05	0.0022	18.0	1.8	1	23	248	270	248	270	0.98
5	11	1.1e-05	0.00067	19.7	2.2	1	23	276	298	276	298	0.99
6	11	0.0001	0.0058	16.7	0.7	1	23	304	326	304	326	0.98
7	11	0.00059	0.034	14.3	1.8	1	23	334	357	334	357	0.96
8	11	0.0004	0.023	14.8	1.2	2	23	364	385	363	385	0.97
9	11	0.002	0.12	12.6	0.7	1	23	391	413	391	413	0.97
10	11	2.2e-05	0.0013	18.8	2.6	1	23	419	442	419	442	0.97
11	11	5.9e-06	0.00034	20.6	3.3	1	23	456	478	456	478	0.96

Sequence Information

Coding Sequence: ATGAGTGCAAAACGCATCAAACAGGAATCAAACGCCAAGAAAAGGGTACCGCAAGAACCAATGCAAATACTGCTTAAGGAAGCTAAGCAAGAGAAGCTGGACATCGATGAGTTGGAGCTTATGACAGCGGGACTGGAGGATGATGACGAAGGCGGATGCTACTTTGTGGATCAGAAGGGCAATTACTACTTTCAGGCCAGTGAAGATGCAGAGCTAAGGGCAGTGGAAAATGGGCCGATCGAATATGAAGCTTTTAATGGCGATCAGGAAAAGGCTGAGGAAGAAGTCAGCTACGTCCTTGTAATGAACGATGGTGACAACAAATCCACAATTGTAGTAAACAACGCCGAAGAGACGAACCTGGAGGAAGCGAAGGACAACGAGATTTACGACTTCGAAGATCCGGATTACATAGTACCGGATCAAACAACCGGCAAAAAGAATACAACACGGGGCAAACGTGGCCAGTCGAGCTCTGGCTCGACGTACATGTGCAATTACTGTAACTACACCAGTAATAAGCTGTTCCTGCTGTCGCGCCATCTGAAAACTCACTCCGATGATCGGCCACACAAGTGCGTTGTGTGCGAGCGAGGCTTTAAAACGCTAGCTTCCTTGCAGAACCACGTAAACACGCACACGGGCACCAAGCCACACCGGTGCAAACATTGCGACAACTGTTTCACGACTTCCGGCGAACTCATCCGGCACATCCGCTATCGACACACGCACGAGCGTCCACACAAGTGCACGGAATGTGACTACGCTAGTGTGGAGTTGAGCAAGCTGAAGCGTCACATCCGTACGCATACCGGTGAAAAGCCGTTCCAGTGTCCGCACTGTACGTACGCATCGCCGGACAAGTTCAAGCTGACGAGACACATGCGAATCCACACCGGCGAGAAGCCTTATTCTTGTGACGTTTGTTTTGCCCGTTTCACTCAGTCCAATTCATTGAAGGCCCACAAAATGATACACCAAGTTGGCAACAAGCCAGTTTTCCAATGCAAACTGTGTCCGACGACCTGCGGTCGCAAAACGGATTTACGCATCCATGTGCAGAACTTACACACGGCCGACAAACCGATCAAGTGCAAGCGCTGTGACAATACCTTCCCCGATCGGTACAGCTACAAAATACACGCGAAAACGCATGAAGGTGAAAAGTGTTACCGGTGCGACTACTGTCCATACGCCTCGATATCGATGCGCCATCTGGAATCGCATCTGCTGCTCCACACGGATCAAAAACCCTACAAGTGTGATCAATGTGCACAGACGTTCCGACAGAAGCAGCTGCTGAAACGGCACATCAACTACTACCACAATCCGGAATACGTTGCACCGACACCGAAAGCGAAAACGCACTCCTGTCCGAGCTGTACGCGATCCTTCCGGCACAAGGGCAACCTCATCCGTCACATGGCGCTGCACGATCCCGACTCGACCATGAGCAAAGAGCTGGAAGCTTTGCGCGAGGGTCGCCAGAAGAAGGTGCAGATCACGTTTGAGGATGAAATGATGTACaagggcgaggaagactacgaaggggaagaagatgaagaggaagaggaggacgaagaagacgaagacgaggaggacgaggagatgggagaggaggaagacgaaTCTCCCGTTCCGATGCAAACGAGTGATGTAGTAACGGTCGAGGATGAGGATGGCCAATACGTGGTGTTGGAAGTGATACAGCTGCAGGATAAAGATAATAAGGCTGCCGATAAGACACCAAAGAAGAGAGCAGCTTCCAAACGTAAGGCAACAGCCACGGTGTTGCCGCAGACGAGTTCCAAACCGACGACATCAGCCGCTGTGGCAACATCATCCCGCGTAACGCGAAGTGTGAAAAAAGAACCAGCAGAAGTGCTTCCGCAACCGGATCCGACACTCGATATGGATGGCATCAATCTGGTGCTGGTGGAGGGTAGCGATGGTGTCCACGATGCACATGAGATTGTGATCGAGCAGGAAAGTGCCGATTCGGGTGATGAGTTCCTTCTCTCCACAGAAGATTTGCAACACACGGAAATGCTGATGTCTTCGCTTAATAACGCAAAACGATCACGCTATGACGTTACCATAAGCCAGGAAGAGTTGGAGAAAAATATGAGCAATTGCTTCGGATTCGATGATGAAGACGATGAAGACTTGGACACCAAAGCAACTATAACGATGCTAAACTAG
Protein Sequence: MSAKRIKQESNAKKRVPQEPMQILLKEAKQEKLDIDELELMTAGLEDDDEGGCYFVDQKGNYYFQASEDAELRAVENGPIEYEAFNGDQEKAEEEVSYVLVMNDGDNKSTIVVNNAEETNLEEAKDNEIYDFEDPDYIVPDQTTGKKNTTRGKRGQSSSGSTYMCNYCNYTSNKLFLLSRHLKTHSDDRPHKCVVCERGFKTLASLQNHVNTHTGTKPHRCKHCDNCFTTSGELIRHIRYRHTHERPHKCTECDYASVELSKLKRHIRTHTGEKPFQCPHCTYASPDKFKLTRHMRIHTGEKPYSCDVCFARFTQSNSLKAHKMIHQVGNKPVFQCKLCPTTCGRKTDLRIHVQNLHTADKPIKCKRCDNTFPDRYSYKIHAKTHEGEKCYRCDYCPYASISMRHLESHLLLHTDQKPYKCDQCAQTFRQKQLLKRHINYYHNPEYVAPTPKAKTHSCPSCTRSFRHKGNLIRHMALHDPDSTMSKELEALREGRQKKVQITFEDEMMYKGEEDYEGEEDEEEEEDEEDEDEEDEEMGEEEDESPVPMQTSDVVTVEDEDGQYVVLEVIQLQDKDNKAADKTPKKRAASKRKATATVLPQTSSKPTTSAAVATSSRVTRSVKKEPAEVLPQPDPTLDMDGINLVLVEGSDGVHDAHEIVIEQESADSGDEFLLSTEDLQHTEMLMSSLNNAKRSRYDVTISQEELEKNMSNCFGFDDEDDEDLDTKATITMLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101849;
90% Identity: iTF_00105298;
80% Identity: -