Basic Information

Insect: Anopheles culicifacies
Gene Symbol: Zfy2
Assembly: GCA_000473375.1
Location: AXCM01000793:12811-24276[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 2 1.1e+02 3.2 0.3 3 23 257 278 257 278 0.96

2 19 4.5 2.6e+02 2.1 0.4 6 23 287 304 287 304 0.91

3 19 0.00044 0.026 14.7 0.2 2 23 309 330 308 330 0.93

4 19 0.0086 0.5 10.6 9.2 1 23 338 360 338 360 0.99

5 19 0.0061 0.36 11.1 0.1 2 23 364 386 363 386 0.96

6 19 0.014 0.8 10.0 0.7 3 23 394 414 392 414 0.95

7 19 0.02 1.2 9.4 0.9 2 23 424 446 423 446 0.96

8 19 0.16 9.6 6.6 1.4 2 23 453 475 452 475 0.92

9 19 9e-05 0.0052 16.9 0.7 1 23 481 503 481 503 0.98

10 19 0.0015 0.085 13.0 1.5 1 23 509 532 509 532 0.97

11 19 4 2.3e+02 2.2 0.1 6 23 804 821 804 821 0.93

12 19 7.4e-05 0.0043 17.1 1.3 2 23 826 848 825 848 0.95

13 19 0.0012 0.068 13.3 1.3 1 23 856 878 856 878 0.96

14 19 0.00031 0.018 15.2 1.1 2 23 882 904 881 904 0.93

15 19 7e-06 0.00041 20.3 0.5 1 23 910 932 910 932 0.96

16 19 0.0014 0.079 13.2 4.4 2 23 942 964 941 964 0.94

17 19 0.012 0.69 10.2 0.5 1 23 971 994 971 994 0.96

18 19 6.2e-08 3.6e-06 26.8 0.7 1 23 999 1021 999 1021 0.98

19 19 0.019 1.1 9.6 2.5 1 23 1027 1051 1027 1051 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	2	1.1e+02	3.2	0.3	3	23	257	278	257	278	0.96
2	19	4.5	2.6e+02	2.1	0.4	6	23	287	304	287	304	0.91
3	19	0.00044	0.026	14.7	0.2	2	23	309	330	308	330	0.93
4	19	0.0086	0.5	10.6	9.2	1	23	338	360	338	360	0.99
5	19	0.0061	0.36	11.1	0.1	2	23	364	386	363	386	0.96
6	19	0.014	0.8	10.0	0.7	3	23	394	414	392	414	0.95
7	19	0.02	1.2	9.4	0.9	2	23	424	446	423	446	0.96
8	19	0.16	9.6	6.6	1.4	2	23	453	475	452	475	0.92
9	19	9e-05	0.0052	16.9	0.7	1	23	481	503	481	503	0.98
10	19	0.0015	0.085	13.0	1.5	1	23	509	532	509	532	0.97
11	19	4	2.3e+02	2.2	0.1	6	23	804	821	804	821	0.93
12	19	7.4e-05	0.0043	17.1	1.3	2	23	826	848	825	848	0.95
13	19	0.0012	0.068	13.3	1.3	1	23	856	878	856	878	0.96
14	19	0.00031	0.018	15.2	1.1	2	23	882	904	881	904	0.93
15	19	7e-06	0.00041	20.3	0.5	1	23	910	932	910	932	0.96
16	19	0.0014	0.079	13.2	4.4	2	23	942	964	941	964	0.94
17	19	0.012	0.69	10.2	0.5	1	23	971	994	971	994	0.96
18	19	6.2e-08	3.6e-06	26.8	0.7	1	23	999	1021	999	1021	0.98
19	19	0.019	1.1	9.6	2.5	1	23	1027	1051	1027	1051	0.96

Sequence Information

Coding Sequence: ATGTTTGTTCATCGAACCCTGCACAACAATAACAAACAGCTGTCAAACAATTGTCAGCGCTGTTGTTGTTGGTACTTGCCCAAGCTCCAAACAAGCCAGGAATGCGTTTTATTGGTTTTATTCATTTTCACAATGAGTAGCGTAGACGAAGTTTGTCGCCTTTGTTTGCGTACATTTGCCCGAGTTGCCAGAGGAAGAATCGCCATCACAAATGAAGTGTTTCAGCCAAAGTTGCAAGCGGTATTTCCGTTTCCCATATTACCAACGGAAACCCTTCCGAGTGATGCCTGCCGTGGATGCCGTGTGATGGTAGAACAATTTTTCGAATACAGTGAAAAGGTCCGATCCAATCAGGCAGATTTAGATGCGGCATTGCCAAACAATGATGAACCCGATTCAGTTGAAGAGGTTAAAGCGGAATTTACCGATACGGCTGCAAGAACACTTTCGGTTGAGACTGACTCCGTCGCGTCCAACGAACATTTACACATCGAACTGCTGAAAGTGGAACCTTTGGTGCAAAGTGCACAACGGGAAGAAAATGCCGAAACAGAGCTCTCAGAACATTTAATTAAATCGGAATCAAACGAAAGTTTGGACGATGATTTCGACGATAATCAAGTTGATGCGCTAACAATGTCCCCGAACGAACAGCCCTGGGACAGTCCGCGTAGGAAGGAACGGAAAGCTCTGGAACCGGTTGCAAGGAAAAAGAAAAGACCCCGAGCTGAGGACGAAATACTGTTGCGCGAACATTTCCATCTTGGGTGTGAAATGTGCACGTTTATGTCAGACACGGTTCCCGATCTCTTTCAGCATTATCGCCAGGAGCACAAAACCGCGGGTTACATTCAGTGCTGCAATCGAAAGTTCTTTCGGCGTGCGCGTTTACTAGAACATCTCGGAGCGCACCTGGGTTCGATAGTGTGCGACATCTGCGGCAAAGTGTTCCGGAATACCTTCTCGCTCGATCTACACAAACTAGACCATGAAGCACCGGATGCGAGACAGTTCAAGTGTGACCAGTGCAGTTTTTCGTTCCACAAACTGTATCATCTGAAGCAGCACCAAAAGCGTCACGAGCGCGTACGCTGCACTATCTGCGATAAGGTGCTGGCGGGTGAGAACGGACTGAAAGGGCATATGCAGAAGATGCACGGAAACGACAACAAACAGATCTGCCCAACCTGTGGGAAAGAGTTTCGTTGCAGTTTGGCGATGGAACGGCACATTAAGGCACACTTGGGCCTTTTAAAGATCGAACGTGTGCAATGTGACCGGTGTGATAAGTGGTTCGGCAGTAAGCTTAACCTCCGGAATCACTTCAAGCGCGTGCATGACGAAGCGGGACCGATTCAGTGTGACGAATGTCAGCACGTAAGTCCCAATCGGAGGGCGCTTCACAATCACAAGGTACGTGCGCATGGCCAgaaacaatcgtacgagtgtgagtactgcggcaagaaactcaacacgaagctcacactgaaggaacacttgtctatacacacgaatattccgctctactcgtgcgagttttgcggcaTCACTTTCAATTCCAACGCGAACAAGTATGTCCATCGTAAGAGCAAACATCCGAAAGAATGGGAGGCTCAAAAGCAACAGAAGCTGTTGAAAAGAATGAGTGCGCCCCGGCGGCCGCTTGCAAACAATGGTGTTCGTCGTAAAAAGCTGTGCACCACAACAGTATCCAAGCGTAAAATGAATGAAAAATGCCGCCTCTGTCTCGGAAATGTATCGAACGAAACGCAAATATCTATACGGGATGCCGCCTTTCACGTGGAATTGAAAAATGTGTTCCATTTTGAGATCGGGCACGACCTGCAACTGCCGCAATACGTGTGCGGTGAATGCAGAGGAACGGTAGCATACATCGACTCATACTGTCAGCAGGTGCAAAACAATCAGGCGCAGCTGATCGGCCAAGCAAAGGAATGCATTCTTCAACCGGTGGAAAATGTAAAAGTGGAATCCCTTCACGATGCTGACTGTTTCGAAGCGGAAGAAAACAATTCAAAAAATGAGCCTAAATTTGGTCGGGATATTCAAACAGCTGTACCGGATAGAACGGTTGGTTCTAATGATGAGAAAGCAGTGAAACAAGCGACAAGGAAAGTTGCAAACTGTGTGGATAAACACAGAACAGGACAAGAAAAATCGTGGCGACGGGATCGCCGAAATATTAGAGAAAAAATAATCATAAGCAGAGAAAATACAGAGCAGGACAGCTCGACGCTAAATGGCCATTCAAAGCAGCTAGAAAATGATCAACTTATAAAAGACTTCTTCACCCTTGAGTGTGAGATCTGTTCTGCACCATTGGAAAGCTTCGTAATGCTGCTGGACCATTATCGGTGTGCACACGATACGAGGGGCTACGTACGCTGCTGTGGTAAGCAATTCTTTCGTCGCTACATACTAGTGGACCATATTGCAGCACACCGTGGGTCAACTCGTTGTGAAATTTGCCAGAAAACGTACAAAACCAAACGCTATCTTATGCTGCATATAGCCAAAAGTCATAGCAGCGAAGAGGAACGACCATTCAAATGTGCCAAGTGTCACATTTCCTATCCCAAACAGTACTTGCTTCGAGCACACGAGCTGCTACACGTCCAGCAACAGTGCCACATTTGCCAGAAGGTGCTCTCGAACAACCAGTCGCTTAAGGTACATCTCGCCCAAATGCACAGTGATGATGGAAATCACATTTGTGACACGTGCGGCAAGGTGTTTCGCACCAAACCGGCCATGGAACGGCACATCAACGAGCATCAAGGGTTGGATGTGGTCGAGCGACTGCAATGCGAGCACTGCCATAAGTGGTTCAGCGGCAAGTACAATCTGAACAAGCATGTACGCTTTCTGCACATGCAAGATGGGCAAGTGTTTCGGTGCGATGTTTGCCAACATGTTAGTCCGAATAGTCGCGCCCTAGCGAATCACAAGCTGCGGATACACGTGGAGGAAAGATTTGAATGTGAGTACTGCGGGAAACGGTTCAAGCGAAGACCGAACTTGCGGGAGCACATTGCAACACACACGAACGTTCCGTTGTATTCGTGTGAAATCTGCGAGAATCGTACATTCAATTCGAAGGCGAATTATTTTACACATCGGAAAAACAAACACCCCCAGGAATGGGAAGCACGTCTTGACAGCTATAGTTGA
Protein Sequence: MFVHRTLHNNNKQLSNNCQRCCCWYLPKLQTSQECVLLVLFIFTMSSVDEVCRLCLRTFARVARGRIAITNEVFQPKLQAVFPFPILPTETLPSDACRGCRVMVEQFFEYSEKVRSNQADLDAALPNNDEPDSVEEVKAEFTDTAARTLSVETDSVASNEHLHIELLKVEPLVQSAQREENAETELSEHLIKSESNESLDDDFDDNQVDALTMSPNEQPWDSPRRKERKALEPVARKKKRPRAEDEILLREHFHLGCEMCTFMSDTVPDLFQHYRQEHKTAGYIQCCNRKFFRRARLLEHLGAHLGSIVCDICGKVFRNTFSLDLHKLDHEAPDARQFKCDQCSFSFHKLYHLKQHQKRHERVRCTICDKVLAGENGLKGHMQKMHGNDNKQICPTCGKEFRCSLAMERHIKAHLGLLKIERVQCDRCDKWFGSKLNLRNHFKRVHDEAGPIQCDECQHVSPNRRALHNHKVRAHGQKQSYECEYCGKKLNTKLTLKEHLSIHTNIPLYSCEFCGITFNSNANKYVHRKSKHPKEWEAQKQQKLLKRMSAPRRPLANNGVRRKKLCTTTVSKRKMNEKCRLCLGNVSNETQISIRDAAFHVELKNVFHFEIGHDLQLPQYVCGECRGTVAYIDSYCQQVQNNQAQLIGQAKECILQPVENVKVESLHDADCFEAEENNSKNEPKFGRDIQTAVPDRTVGSNDEKAVKQATRKVANCVDKHRTGQEKSWRRDRRNIREKIIISRENTEQDSSTLNGHSKQLENDQLIKDFFTLECEICSAPLESFVMLLDHYRCAHDTRGYVRCCGKQFFRRYILVDHIAAHRGSTRCEICQKTYKTKRYLMLHIAKSHSSEEERPFKCAKCHISYPKQYLLRAHELLHVQQQCHICQKVLSNNQSLKVHLAQMHSDDGNHICDTCGKVFRTKPAMERHINEHQGLDVVERLQCEHCHKWFSGKYNLNKHVRFLHMQDGQVFRCDVCQHVSPNSRALANHKLRIHVEERFECEYCGKRFKRRPNLREHIATHTNVPLYSCEICENRTFNSKANYFTHRKNKHPQEWEARLDSYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -